Linshang Chemical
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2,4-Dichlorobenzeneacetyl Chloride
Linshang Chemical
|
HS Code |
895917 |
| Chemical Formula | C8H5Cl3O |
| Molar Mass | 223.485 g/mol |
| Appearance | Typically a colorless to light - yellow liquid |
| Odor | Pungent, irritating odor |
| Density | Data needed |
| Boiling Point | Data needed |
| Melting Point | Data needed |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like benzene, toluene |
| Flash Point | Data needed |
| Hazard Class | Corrosive, harmful if inhaled or in contact with skin |
As an accredited 2,4-Dichlorobenzeneacetyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 - gram bottle packaging for 2,4 - dichlorobenzeneacetyl Chloride chemical. |
| Storage | 2,4 - dichlorobenzeneacetyl Chloride should be stored in a cool, dry, well - ventilated area, away from sources of heat and ignition. It should be stored in tightly - sealed containers, preferably made of corrosion - resistant materials. Keep it separate from incompatible substances like bases, alcohols, and water to prevent dangerous reactions. |
| Shipping | 2,4 - dichlorobenzeneacetyl Chloride is a hazardous chemical. It must be shipped in accordance with strict regulations. Use specialized containers, ensure proper labeling, and transport with carriers licensed for hazardous substances to guarantee safety. |
Competitive 2,4-Dichlorobenzeneacetyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 2,4-Dichlorobenzeneacetyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2,4-dichlorophenylacetyl chloride?
2% 2C4-difluorophenylacetic acid is an organic compound with a wide range of main uses.
In the field of pharmaceutical synthesis, this compound is of great significance. It is often used as a key intermediate in the preparation of many drugs. For example, during the construction of some drug molecules with specific biological activities, 2% 2C4-difluorophenylacetic acid can skillfully connect other functional groups through specific chemical reactions, thus constructing complex drug structures with therapeutic effects. It is like an important cornerstone for building a drug building, providing an indispensable starting material for the development of new drugs, and helping medical workers create more innovative drugs with significant efficacy and few side effects.
In the field of pesticides, 2% 2C4-difluorophenylacetic acid also plays an important role. It can be used as an important part of the synthesis of high-efficiency pesticides. With its unique chemical structure, the synthesized pesticides often have excellent insecticidal, bactericidal or weeding properties. These pesticides can not only effectively resist the invasion of crop diseases and insect pests and improve crop yield, but also because of their structural characteristics, they have good degradability in the environment and relatively small negative impact on the ecological environment, which is conducive to the sustainable development of agriculture.
In addition, in the field of fine chemicals, 2% 2C4-difluorophenylacetic acid is also often used to synthesize various fine chemicals. These fine chemicals are widely used in flavors, coatings, plastic additives and other aspects, contributing to improving product performance and enriching product variety. For example, in the synthesis of fragrances, it can participate in the reaction to generate compounds with unique aromas, adding new aroma components to the fragrance industry; in the field of coatings, its derivatives can improve the adhesion, corrosion resistance and other properties of coatings, so that coatings can better protect the coated objects in various environments. In short, 2% 2C4-difluorophenylacetic acid plays a key role in many fields, promoting the continuous development and progress of related industries.
In the field of pharmaceutical synthesis, this compound is of great significance. It is often used as a key intermediate in the preparation of many drugs. For example, during the construction of some drug molecules with specific biological activities, 2% 2C4-difluorophenylacetic acid can skillfully connect other functional groups through specific chemical reactions, thus constructing complex drug structures with therapeutic effects. It is like an important cornerstone for building a drug building, providing an indispensable starting material for the development of new drugs, and helping medical workers create more innovative drugs with significant efficacy and few side effects.
In the field of pesticides, 2% 2C4-difluorophenylacetic acid also plays an important role. It can be used as an important part of the synthesis of high-efficiency pesticides. With its unique chemical structure, the synthesized pesticides often have excellent insecticidal, bactericidal or weeding properties. These pesticides can not only effectively resist the invasion of crop diseases and insect pests and improve crop yield, but also because of their structural characteristics, they have good degradability in the environment and relatively small negative impact on the ecological environment, which is conducive to the sustainable development of agriculture.
In addition, in the field of fine chemicals, 2% 2C4-difluorophenylacetic acid is also often used to synthesize various fine chemicals. These fine chemicals are widely used in flavors, coatings, plastic additives and other aspects, contributing to improving product performance and enriching product variety. For example, in the synthesis of fragrances, it can participate in the reaction to generate compounds with unique aromas, adding new aroma components to the fragrance industry; in the field of coatings, its derivatives can improve the adhesion, corrosion resistance and other properties of coatings, so that coatings can better protect the coated objects in various environments. In short, 2% 2C4-difluorophenylacetic acid plays a key role in many fields, promoting the continuous development and progress of related industries.
What are the physical properties of 2,4-dichlorophenylacetyl chloride?
2% 2C4-difluorobenzyl bromide is a commonly used reagent in organic synthesis. Its physical properties are quite unique and play a key role in many chemical synthesis reactions.
Looking at its properties, under room temperature and pressure, 2% 2C4-difluorobenzyl bromide is a colorless to light yellow liquid with a clear appearance and a certain fluidity. This substance has a special odor. However, because the smell is difficult to describe accurately in words, it is often perceived by smelling it yourself.
When it comes to density, its density is greater than that of water, about [specific value] g/cm ³. This property causes it to sink to the bottom when mixed with water. This density property is of great significance in many experimental operations or industrial production processes involving liquid-liquid separation. For example, in some reaction systems, the difference in density from water can be used to achieve preliminary separation by means of liquid separation, which in turn facilitates the purification and subsequent processing of the product.
The boiling point is also one of its important physical properties. The boiling point of 2% 2C4-difluorobenzyl bromide is about [specific value] ° C. Knowing the boiling point is crucial to controlling its state change during operations such as heating or distillation. In chemical synthesis experiments, the distillation process often achieves the purpose of separation and purification according to the different boiling points of substances. When a mixture containing 2% 2C4-difluorobenzyl bromide is distilled to its boiling point temperature, the substance will vaporize, and then it will be condensed and re-converted into a liquid state to achieve separation from other substances with different boiling points.
In addition, 2% 2C4-difluorobenzyl bromide has good solubility in organic solvents, such as common organic solvents such as ethanol, ether, and dichloromethane. This solubility property provides convenience for many organic synthesis reactions. When designing a synthesis route, a suitable organic solvent can be selected according to the reaction requirements to fully mix the reactants and promote the smooth progress of the reaction. For example, in the nucleophilic substitution reaction, selecting a suitable organic solvent to dissolve 2% 2C4-difluorobenzyl bromide and nucleophilic reagent can increase the probability of contact between the two, and improve the reaction rate and yield.
However, 2% 2C4-difluorobenzyl bromide is toxic and corrosive, and it is necessary to strictly follow safety procedures when operating, and take protective measures, such as wearing protective gloves, goggles, and operating in a well-ventilated environment, to prevent harm to the human body.
Looking at its properties, under room temperature and pressure, 2% 2C4-difluorobenzyl bromide is a colorless to light yellow liquid with a clear appearance and a certain fluidity. This substance has a special odor. However, because the smell is difficult to describe accurately in words, it is often perceived by smelling it yourself.
When it comes to density, its density is greater than that of water, about [specific value] g/cm ³. This property causes it to sink to the bottom when mixed with water. This density property is of great significance in many experimental operations or industrial production processes involving liquid-liquid separation. For example, in some reaction systems, the difference in density from water can be used to achieve preliminary separation by means of liquid separation, which in turn facilitates the purification and subsequent processing of the product.
The boiling point is also one of its important physical properties. The boiling point of 2% 2C4-difluorobenzyl bromide is about [specific value] ° C. Knowing the boiling point is crucial to controlling its state change during operations such as heating or distillation. In chemical synthesis experiments, the distillation process often achieves the purpose of separation and purification according to the different boiling points of substances. When a mixture containing 2% 2C4-difluorobenzyl bromide is distilled to its boiling point temperature, the substance will vaporize, and then it will be condensed and re-converted into a liquid state to achieve separation from other substances with different boiling points.
In addition, 2% 2C4-difluorobenzyl bromide has good solubility in organic solvents, such as common organic solvents such as ethanol, ether, and dichloromethane. This solubility property provides convenience for many organic synthesis reactions. When designing a synthesis route, a suitable organic solvent can be selected according to the reaction requirements to fully mix the reactants and promote the smooth progress of the reaction. For example, in the nucleophilic substitution reaction, selecting a suitable organic solvent to dissolve 2% 2C4-difluorobenzyl bromide and nucleophilic reagent can increase the probability of contact between the two, and improve the reaction rate and yield.
However, 2% 2C4-difluorobenzyl bromide is toxic and corrosive, and it is necessary to strictly follow safety procedures when operating, and take protective measures, such as wearing protective gloves, goggles, and operating in a well-ventilated environment, to prevent harm to the human body.
What are the chemical properties of 2,4-dichlorophenylacetyl chloride?
2% 2C4 -difluorobenzyl bromide is an organic compound with unique chemical properties and extraordinary effects in the field of organic synthesis. Although the traditional process involved in "Tiangong Kaiwu" is not directly recorded, it can be explained as follows in ancient Chinese:
This substance has active chemical activity, and its bromine atom is active and easy to nucleophilic substitution reaction. In case of nucleophilic reagents, bromine atoms are easily replaced, thereby forming new carbon-heteroatom bonds. This reaction process is just like the ancient craftsmen who used exquisite techniques to exert force in subtle places to reshape the structure of the substance.
The existence of fluorine atoms significantly affects the physical and chemical properties of molecules. The high electronegativity of fluorine atoms changes the polarity of molecules, which in turn affects their solubility and stability. In the reaction, fluorine atoms can use the induction effect and conjugation effect to affect the reactivity and selectivity, just like the art of war, strategizing and controlling the direction of the reaction.
In addition, the chemical properties of 2% 2C4-difluorobenzyl bromide make it very popular in the synthesis of fine chemicals such as medicine and pesticides. It can be converted into compounds with specific biological activities through a series of reactions. For example, the introduction of this structural unit into drug molecules may improve the pharmacological properties of drugs, just like injecting unique effects into drugs to achieve the purpose of treating patients and saving people.
When storing and using this substance, caution is required. Due to its lively chemical properties, in case of improper conditions or dangerous reactions, just like keeping flammable materials, it must be handled with caution to ensure safety.
This substance has active chemical activity, and its bromine atom is active and easy to nucleophilic substitution reaction. In case of nucleophilic reagents, bromine atoms are easily replaced, thereby forming new carbon-heteroatom bonds. This reaction process is just like the ancient craftsmen who used exquisite techniques to exert force in subtle places to reshape the structure of the substance.
The existence of fluorine atoms significantly affects the physical and chemical properties of molecules. The high electronegativity of fluorine atoms changes the polarity of molecules, which in turn affects their solubility and stability. In the reaction, fluorine atoms can use the induction effect and conjugation effect to affect the reactivity and selectivity, just like the art of war, strategizing and controlling the direction of the reaction.
In addition, the chemical properties of 2% 2C4-difluorobenzyl bromide make it very popular in the synthesis of fine chemicals such as medicine and pesticides. It can be converted into compounds with specific biological activities through a series of reactions. For example, the introduction of this structural unit into drug molecules may improve the pharmacological properties of drugs, just like injecting unique effects into drugs to achieve the purpose of treating patients and saving people.
When storing and using this substance, caution is required. Due to its lively chemical properties, in case of improper conditions or dangerous reactions, just like keeping flammable materials, it must be handled with caution to ensure safety.
What is the production method of 2,4-dichlorophenylacetyl chloride?
2% 2C4-difluorobenzyl bromide. There are several common methods for its preparation.
First, 2,4-difluorotoluene is used as the starting material. Under the condition of light or the presence of an initiator, 2,4-difluorotoluene undergoes a free radical substitution reaction with bromine. In this reaction, bromine radicals attack the hydrogen atom at the benzyl position, thereby generating 2,4-difluorobenzyl bromide. Pay attention to the reaction temperature, light intensity and the amount of bromine, because it has a great impact on the process of the reaction and the purity of the product. If the temperature is too high, it may cause the formation of polybrominated products; if the amount of bromine is not appropriate, it will also affect the yield of the product.
Second, it can be started from 2,4-difluorobenzoic acid. First, 2,4-difluorobenzoic acid is reduced to 2,4-difluorobenzyl alcohol. Commonly used reducing agents include lithium aluminum hydride. Then, 2,4-difluorobenzyl alcohol is reacted with reagents such as hydrobromic acid or phosphorus tribromide to replace the hydroxyl group with a bromine atom, and then 2,4-difluorobenzyl bromide is obtained. In this path, the reduction step needs to be carried out in an anhydrous and low temperature environment to ensure the smooth and safe reaction; the reaction of alcohol to bromide also needs to control the reaction conditions to improve the purity and yield of the product.
Alternatively, 2,4-difluorobenzaldehyde is used as raw material and prepared through a series of reactions. First, 2,4-difluorobenzaldehyde is reduced to 2,4-difluorobenzyl alcohol, and then the above steps are carried out to convert the alcohol into bromide. In this process, the control of the purity of the raw material, the amount of reaction reagents and the reaction conditions are all related to the quality and yield of the final product. The reaction parameters need to be fine-tuned according to the actual situation to achieve the desired preparation effect.
First, 2,4-difluorotoluene is used as the starting material. Under the condition of light or the presence of an initiator, 2,4-difluorotoluene undergoes a free radical substitution reaction with bromine. In this reaction, bromine radicals attack the hydrogen atom at the benzyl position, thereby generating 2,4-difluorobenzyl bromide. Pay attention to the reaction temperature, light intensity and the amount of bromine, because it has a great impact on the process of the reaction and the purity of the product. If the temperature is too high, it may cause the formation of polybrominated products; if the amount of bromine is not appropriate, it will also affect the yield of the product.
Second, it can be started from 2,4-difluorobenzoic acid. First, 2,4-difluorobenzoic acid is reduced to 2,4-difluorobenzyl alcohol. Commonly used reducing agents include lithium aluminum hydride. Then, 2,4-difluorobenzyl alcohol is reacted with reagents such as hydrobromic acid or phosphorus tribromide to replace the hydroxyl group with a bromine atom, and then 2,4-difluorobenzyl bromide is obtained. In this path, the reduction step needs to be carried out in an anhydrous and low temperature environment to ensure the smooth and safe reaction; the reaction of alcohol to bromide also needs to control the reaction conditions to improve the purity and yield of the product.
Alternatively, 2,4-difluorobenzaldehyde is used as raw material and prepared through a series of reactions. First, 2,4-difluorobenzaldehyde is reduced to 2,4-difluorobenzyl alcohol, and then the above steps are carried out to convert the alcohol into bromide. In this process, the control of the purity of the raw material, the amount of reaction reagents and the reaction conditions are all related to the quality and yield of the final product. The reaction parameters need to be fine-tuned according to the actual situation to achieve the desired preparation effect.
What should be paid attention to when storing and transporting 2,4-dichlorophenylacetyl chloride?
2% 2C4-difluorobenzyl bromide is a highly toxic product. Its storage and transportation are life-threatening, and it is necessary to be cautious and strictly follow the procedures.
When storing, first choose a cool, dry and well-ventilated place. This substance is easy to decompose when heated, causing increased toxicity, or the risk of ignition, so it is necessary to avoid heat sources and open flames. And it is necessary to keep away from oxidants, alkalis and other substances to prevent severe reactions. Because of its strong corrosiveness, the storage container should be made of corrosion-resistant materials, such as glass or specific plastics, to ensure a tight seal to prevent leakage. In addition, the warehouse should be clearly marked with warning signs, and unrelated people should be strictly prohibited from approaching.
When transporting, it is necessary to choose professional transportation tools and equip professional personnel in accordance with relevant regulations. Transportation vehicles should have perfect ventilation and fire protection facilities to prevent accidents. During loading and unloading, operators must wear professional protective equipment, such as gas masks, protective clothing and protective gloves, and operate strictly to prevent package damage. During transportation, the condition of the goods should be checked regularly. If there is any leakage, take emergency measures immediately, evacuate the surrounding people, and report to the relevant departments.
In short, the storage and transportation of 2% 2C4-difluorobenzyl bromide must not be slack at all, and must be treated in a professional and rigorous manner to ensure the safety of personnel and the environment.
When storing, first choose a cool, dry and well-ventilated place. This substance is easy to decompose when heated, causing increased toxicity, or the risk of ignition, so it is necessary to avoid heat sources and open flames. And it is necessary to keep away from oxidants, alkalis and other substances to prevent severe reactions. Because of its strong corrosiveness, the storage container should be made of corrosion-resistant materials, such as glass or specific plastics, to ensure a tight seal to prevent leakage. In addition, the warehouse should be clearly marked with warning signs, and unrelated people should be strictly prohibited from approaching.
When transporting, it is necessary to choose professional transportation tools and equip professional personnel in accordance with relevant regulations. Transportation vehicles should have perfect ventilation and fire protection facilities to prevent accidents. During loading and unloading, operators must wear professional protective equipment, such as gas masks, protective clothing and protective gloves, and operate strictly to prevent package damage. During transportation, the condition of the goods should be checked regularly. If there is any leakage, take emergency measures immediately, evacuate the surrounding people, and report to the relevant departments.
In short, the storage and transportation of 2% 2C4-difluorobenzyl bromide must not be slack at all, and must be treated in a professional and rigorous manner to ensure the safety of personnel and the environment.
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