Linshang Chemical
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2,5-Dichloro-1-Hydroxy-Benzene
Linshang Chemical
|
HS Code |
502629 |
| Chemical Formula | C6H4Cl2O |
| Molar Mass | 163.00 g/mol |
| Appearance | White to off - white solid |
| Melting Point | 58 - 62 °C |
| Boiling Point | 245 - 247 °C |
| Solubility In Water | Slightly soluble |
| Solubility In Organic Solvents | Soluble in ethanol, ether, etc. |
| Density | 1.544 g/cm³ |
| Odor | Pungent |
| Flash Point | 110 °C |
As an accredited 2,5-Dichloro-1-Hydroxy-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 2,5 - dichloro - 1 - hydroxy - benzene in a sealed chemical - resistant bottle. |
| Storage | 2,5 - dichloro - 1 - hydroxy - benzene, also known as 2,5 - dichlorophenol, should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and contact with air or moisture which could potentially lead to decomposition or reaction. |
| Shipping | 2,5 - dichloro - 1 - hydroxy - benzene is shipped in tightly - sealed, corrosion - resistant containers. Shipments follow strict chemical transportation regulations, ensuring proper handling to prevent spills and exposure during transit. |
Competitive 2,5-Dichloro-1-Hydroxy-Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,5-Dichloro-1-Hydroxy-Benzene in China?
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As a leading 2,5-Dichloro-1-Hydroxy-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2,5-dichloro-1-hydroxybenzene?
2% 2C5-difluoro-1-methoxybenzene, an organic compound, has important uses in many fields.
In the field of medicinal chemistry, it is a key pharmaceutical intermediate. With its unique chemical structure, it can be converted into drug molecules with specific pharmacological activities through a series of chemical reactions. For example, in the synthesis of some new antimicrobial drugs and drugs for the treatment of nervous system diseases, 2% 2C5-difluoro-1-methoxybenzene can be introduced as a starting material or a key structural fragment, which has a significant impact on the activity, selectivity and pharmacokinetic properties of drug molecules.
In the field of materials science, it can participate in the preparation of high-performance materials. Such as the preparation of special fluoropolymer materials, 2% 2C5-difluoro-1-methoxybenzene as a fluorine-containing monomer can endow the polymer with excellent thermal stability, chemical stability and low surface energy. These properties make such polymer materials widely used in high-end fields such as aerospace and electronic devices, such as special coating materials in the aerospace field, insulating materials in electronic devices, etc.
In the field of pesticide chemistry, it is also an important synthetic raw material. New pesticides with high efficiency, low toxicity and environmental friendliness can be synthesized. Due to the fluorine atoms and methoxy groups in its structure, it can enhance the interaction between pesticide molecules and specific receptors in target organisms, thereby enhancing the insecticidal, bactericidal or herbicidal activity of pesticides, while reducing the toxicity to non-target organisms and reducing the negative impact on the environment.
In the field of medicinal chemistry, it is a key pharmaceutical intermediate. With its unique chemical structure, it can be converted into drug molecules with specific pharmacological activities through a series of chemical reactions. For example, in the synthesis of some new antimicrobial drugs and drugs for the treatment of nervous system diseases, 2% 2C5-difluoro-1-methoxybenzene can be introduced as a starting material or a key structural fragment, which has a significant impact on the activity, selectivity and pharmacokinetic properties of drug molecules.
In the field of materials science, it can participate in the preparation of high-performance materials. Such as the preparation of special fluoropolymer materials, 2% 2C5-difluoro-1-methoxybenzene as a fluorine-containing monomer can endow the polymer with excellent thermal stability, chemical stability and low surface energy. These properties make such polymer materials widely used in high-end fields such as aerospace and electronic devices, such as special coating materials in the aerospace field, insulating materials in electronic devices, etc.
In the field of pesticide chemistry, it is also an important synthetic raw material. New pesticides with high efficiency, low toxicity and environmental friendliness can be synthesized. Due to the fluorine atoms and methoxy groups in its structure, it can enhance the interaction between pesticide molecules and specific receptors in target organisms, thereby enhancing the insecticidal, bactericidal or herbicidal activity of pesticides, while reducing the toxicity to non-target organisms and reducing the negative impact on the environment.
What are the physical properties of 2,5-dichloro-1-hydroxybenzene?
2% 2C5-difluoro-1-methoxybenzene is a kind of organic compound. Its physical properties are quite unique, as follows:
Looking at its properties, under normal temperature and pressure, it is mostly a colorless and transparent liquid, with a pure texture and few impurities. Under the illumination of light, it often appears clear and shiny, just like a pool of autumn water, quiet and clear.
As for the boiling point, it is about a specific temperature range. At this temperature point, the substance gradually converts from liquid to gaseous, and the force between molecules gradually weakens, allowing it to escape into space. The value of this boiling point is a key indicator for various chemical reactions and separation processes, and is related to the setting of operating temperature and the control of conditions.
Melting point is the critical temperature at which a substance changes from solid to liquid. The melting point of 2% 2C5-difluoro-1-methoxybenzene is also a specific value. When the ambient temperature drops below this melting point, the molecular movement slows down and the arrangement tends to be orderly. Then it condenses into a solid state, just like everything is hidden in winter, quiet and stable.
Its density is a certain value under the corresponding conditions. This value reflects the mass of the substance in a unit volume, reflecting the compactness of its molecules and the way of accumulation. It is indispensable for the study of the measurement, mixing and phase distribution of materials in chemical production. In terms of solubility, the substance exhibits good solubility properties in specific organic solvents, and can miscible with some organic solvents in a specific ratio to form a uniform mixing system. In water, its solubility is relatively limited. This difference is due to the difference between the molecular structure of the substance and the interaction between water molecules and organic solvent molecules. This property has important practical guiding value in the extraction, purification and choice of reaction medium of the substance.
In addition, the vapor pressure of 2% 2C5 -difluoro-1 -methoxybenzene also varies accordingly at different temperatures. The size of the vapor pressure reflects the difficulty of volatilization of the substance, and provides an important reference for its storage, transportation, and production environment in terms of vapor emission and concentration control.
Looking at its properties, under normal temperature and pressure, it is mostly a colorless and transparent liquid, with a pure texture and few impurities. Under the illumination of light, it often appears clear and shiny, just like a pool of autumn water, quiet and clear.
As for the boiling point, it is about a specific temperature range. At this temperature point, the substance gradually converts from liquid to gaseous, and the force between molecules gradually weakens, allowing it to escape into space. The value of this boiling point is a key indicator for various chemical reactions and separation processes, and is related to the setting of operating temperature and the control of conditions.
Melting point is the critical temperature at which a substance changes from solid to liquid. The melting point of 2% 2C5-difluoro-1-methoxybenzene is also a specific value. When the ambient temperature drops below this melting point, the molecular movement slows down and the arrangement tends to be orderly. Then it condenses into a solid state, just like everything is hidden in winter, quiet and stable.
Its density is a certain value under the corresponding conditions. This value reflects the mass of the substance in a unit volume, reflecting the compactness of its molecules and the way of accumulation. It is indispensable for the study of the measurement, mixing and phase distribution of materials in chemical production. In terms of solubility, the substance exhibits good solubility properties in specific organic solvents, and can miscible with some organic solvents in a specific ratio to form a uniform mixing system. In water, its solubility is relatively limited. This difference is due to the difference between the molecular structure of the substance and the interaction between water molecules and organic solvent molecules. This property has important practical guiding value in the extraction, purification and choice of reaction medium of the substance.
In addition, the vapor pressure of 2% 2C5 -difluoro-1 -methoxybenzene also varies accordingly at different temperatures. The size of the vapor pressure reflects the difficulty of volatilization of the substance, and provides an important reference for its storage, transportation, and production environment in terms of vapor emission and concentration control.
What are the chemical properties of 2,5-dichloro-1-hydroxybenzene?
2% 2C5-difluoro-1-methoxybenzene has unique chemical properties and has the following numbers.
First, this substance has certain stability. Due to the introduction of fluorine atoms, its carbon-fluorine bond energy is quite high, which makes the molecular skeleton relatively stable and not easy to break the bond under normal conditions. Therefore, in the usual chemical environment, it can maintain the relative stability of the structure and is not easy to decompose or deteriorate rapidly due to ordinary heat, light and other factors.
Second, due to the strong electronegativity of fluorine atoms, the compound has obvious polarity. Fluorine atoms strongly attract electron clouds, which makes the molecular charge distribution uneven, which affects its physical and chemical properties. For example, in terms of solubility, compared with some non-polar compounds, it may have better solubility in polar solvents. Due to the principle of "similar miscibility", polar molecules are easy to interact with polar solvents.
Third, the presence of methoxy groups also gives it special chemical activity. Methoxy groups are power supply subgroups, which can increase the electron cloud density on the benzene ring through conjugation effect. In this way, the benzene ring is more prone to electrophilic substitution reactions, such as halogenation, nitration, sulfonation, etc. When the electrophilic reagent attacks, the benzene ring sites activated by the methoxy group will preferentially react, and the reactive activity is enhanced compared with the unsubstituted benzene.
Fourth, this compound may participate in specific organic synthesis reactions. Due to the characteristics of fluorine atoms and methoxy groups, it can be used as a key intermediate to play an important role in the construction of more complex organic molecular structures. For example, it can be modified and expanded by condensation and substitution with other compounds containing active groups, thus providing an important starting material for the synthesis of organic compounds such as drugs and materials with specific functions.
First, this substance has certain stability. Due to the introduction of fluorine atoms, its carbon-fluorine bond energy is quite high, which makes the molecular skeleton relatively stable and not easy to break the bond under normal conditions. Therefore, in the usual chemical environment, it can maintain the relative stability of the structure and is not easy to decompose or deteriorate rapidly due to ordinary heat, light and other factors.
Second, due to the strong electronegativity of fluorine atoms, the compound has obvious polarity. Fluorine atoms strongly attract electron clouds, which makes the molecular charge distribution uneven, which affects its physical and chemical properties. For example, in terms of solubility, compared with some non-polar compounds, it may have better solubility in polar solvents. Due to the principle of "similar miscibility", polar molecules are easy to interact with polar solvents.
Third, the presence of methoxy groups also gives it special chemical activity. Methoxy groups are power supply subgroups, which can increase the electron cloud density on the benzene ring through conjugation effect. In this way, the benzene ring is more prone to electrophilic substitution reactions, such as halogenation, nitration, sulfonation, etc. When the electrophilic reagent attacks, the benzene ring sites activated by the methoxy group will preferentially react, and the reactive activity is enhanced compared with the unsubstituted benzene.
Fourth, this compound may participate in specific organic synthesis reactions. Due to the characteristics of fluorine atoms and methoxy groups, it can be used as a key intermediate to play an important role in the construction of more complex organic molecular structures. For example, it can be modified and expanded by condensation and substitution with other compounds containing active groups, thus providing an important starting material for the synthesis of organic compounds such as drugs and materials with specific functions.
What is the production method of 2,5-dichloro-1-hydroxybenzene?
The preparation of 2% 2C5-difluoro-1-methoxynaphthalene involves many steps and techniques.
First, appropriate raw materials need to be prepared. To make this substance, naphthalene and its derivatives are often used as starting materials. Naphthalene-based, with stable structure and aromatic ring, is the basis for constructing target molecules. High-purity naphthalene can be purchased from the chemical market, or from natural resources such as coal tar through fractionation and extraction.
Second, fluorine atoms are introduced. This is a key step, which is related to the characteristics of the product. Nucleophilic substitution or electrophilic substitution reactions are commonly used. For nucleophilic substitution, suitable fluorinated reagents, such as potassium fluoride, can be selected to react with naphthalene derivatives under the action of specific solvents and catalysts. Electrophilic substitution often requires Lewis acid catalysts, such as aluminum trichloride, to promote the binding of fluorine atoms to specific positions in the naphthalene ring. This process requires precise regulation of reaction temperature, time and reagent dosage, so that fluorine-retaining atoms are precisely introduced into the 2,5-position.
Furthermore, methoxy is added. Halogenated naphthalene derivatives can be reacted with alkoxides such as sodium methoxide by Williamson ether synthesis method. This reaction is carried out in an appropriate solvent such as dimethylformamide (DMF), which can improve the reaction efficiency. Also pay attention to the reaction conditions to prevent side reactions, such as hydrolysis of halogens.
After the reaction is completed, the product needs to be separated and purified. Distillation, recrystallization, column chromatography and other methods can be used. Distillation separates according to the difference in boiling point between the product and the impurity; recrystallization selects a suitable solvent to dissolve the product and precipitate it at low temperature; column chromatography separates according to the adsorption and partition coefficient of the substance in the stationary phase and the mobile phase. After these steps, high purity 2,5-difluoro-1-methoxynaphthalene can be obtained. However, in actual preparation, each step needs to be fine-tuned according to specific experimental conditions and requirements to achieve satisfactory results.
First, appropriate raw materials need to be prepared. To make this substance, naphthalene and its derivatives are often used as starting materials. Naphthalene-based, with stable structure and aromatic ring, is the basis for constructing target molecules. High-purity naphthalene can be purchased from the chemical market, or from natural resources such as coal tar through fractionation and extraction.
Second, fluorine atoms are introduced. This is a key step, which is related to the characteristics of the product. Nucleophilic substitution or electrophilic substitution reactions are commonly used. For nucleophilic substitution, suitable fluorinated reagents, such as potassium fluoride, can be selected to react with naphthalene derivatives under the action of specific solvents and catalysts. Electrophilic substitution often requires Lewis acid catalysts, such as aluminum trichloride, to promote the binding of fluorine atoms to specific positions in the naphthalene ring. This process requires precise regulation of reaction temperature, time and reagent dosage, so that fluorine-retaining atoms are precisely introduced into the 2,5-position.
Furthermore, methoxy is added. Halogenated naphthalene derivatives can be reacted with alkoxides such as sodium methoxide by Williamson ether synthesis method. This reaction is carried out in an appropriate solvent such as dimethylformamide (DMF), which can improve the reaction efficiency. Also pay attention to the reaction conditions to prevent side reactions, such as hydrolysis of halogens.
After the reaction is completed, the product needs to be separated and purified. Distillation, recrystallization, column chromatography and other methods can be used. Distillation separates according to the difference in boiling point between the product and the impurity; recrystallization selects a suitable solvent to dissolve the product and precipitate it at low temperature; column chromatography separates according to the adsorption and partition coefficient of the substance in the stationary phase and the mobile phase. After these steps, high purity 2,5-difluoro-1-methoxynaphthalene can be obtained. However, in actual preparation, each step needs to be fine-tuned according to specific experimental conditions and requirements to achieve satisfactory results.
What are the precautions for using 2,5-dichloro-1-hydroxybenzene?
2% 2C5-difluoro-1-methoxybenzene is a commonly used raw material in organic synthesis. When using it, many matters must be paid attention to.
First, safety protection is of paramount importance. This substance is toxic and irritating to a certain extent. When operating, be sure to wear suitable protective equipment, such as gas masks, protective gloves and goggles, to prevent skin contact and inhalation of its volatile gas, which can damage health.
Second, storage conditions should not be ignored. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and protected from direct sunlight. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to avoid dangerous chemical reactions.
Third, the access operation must be rigorous. Use clean and dry appliances to prevent impurities from mixing. Accurately control the dosage, avoid waste, and operate in the fume hood to ensure that the volatile gas can be discharged in time and reduce the indoor concentration.
Fourth, the suitability of chemical reactions needs to be considered in detail. When participating in various chemical reactions, the reaction conditions, solvents and catalysts should be reasonably selected according to their chemical characteristics. If the reaction conditions are improper, or the reaction yield is low, or even cause side reactions and generate impurities.
Fifth, waste treatment must be in compliance. Residues and waste after use cannot be discarded at will, and must be properly disposed of in accordance with relevant regulations to prevent pollution to the environment.
In short, when using 2% 2C5-difluoro-1-methoxybenzene, many aspects such as safety, storage, operation, reaction and waste disposal need to be treated with caution to ensure the safety and efficiency of the use process.
First, safety protection is of paramount importance. This substance is toxic and irritating to a certain extent. When operating, be sure to wear suitable protective equipment, such as gas masks, protective gloves and goggles, to prevent skin contact and inhalation of its volatile gas, which can damage health.
Second, storage conditions should not be ignored. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and protected from direct sunlight. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to avoid dangerous chemical reactions.
Third, the access operation must be rigorous. Use clean and dry appliances to prevent impurities from mixing. Accurately control the dosage, avoid waste, and operate in the fume hood to ensure that the volatile gas can be discharged in time and reduce the indoor concentration.
Fourth, the suitability of chemical reactions needs to be considered in detail. When participating in various chemical reactions, the reaction conditions, solvents and catalysts should be reasonably selected according to their chemical characteristics. If the reaction conditions are improper, or the reaction yield is low, or even cause side reactions and generate impurities.
Fifth, waste treatment must be in compliance. Residues and waste after use cannot be discarded at will, and must be properly disposed of in accordance with relevant regulations to prevent pollution to the environment.
In short, when using 2% 2C5-difluoro-1-methoxybenzene, many aspects such as safety, storage, operation, reaction and waste disposal need to be treated with caution to ensure the safety and efficiency of the use process.
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