2,5-Dichloro-Benzeneethanamine

Linshang Chemical

Specifications

HS Code

710389

Chemical Formula C8H7Cl2N
Molecular Weight 188.05
Appearance Solid (usually white or off - white)
Odor Characteristic organic odor
Melting Point Data needed
Boiling Point Data needed
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, chloroform
Density Data needed
Vapor Pressure Data needed
Stability Stable under normal conditions
Hazard Class Toxic, harmful to the environment (data for specific hazards needed)

As an accredited 2,5-Dichloro-Benzeneethanamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,5 - dichloro - benzeneethanamine packaged in a sealed chemical - grade bottle.
Storage 2,5 - dichloro - benzeneethanamine should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents, acids, and bases to avoid chemical reactions. Label the storage container clearly for easy identification and safety.
Shipping 2,5 - dichloro - benzeneethanamine is a chemical. Shipping should follow strict regulations. It must be properly packaged in corrosion - resistant containers, labeled clearly, and transported by carriers licensed for hazardous chemicals to ensure safety.
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2,5-Dichloro-Benzeneethanamine 2,5-Dichloro-Benzeneethanamine
General Information
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Frequently Asked Questions

As a leading 2,5-Dichloro-Benzeneethanamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2,5-dichlorophenethylamine?
2% 2C5-difluorobenzyl bromide is a commonly used chemical substance in organic synthesis. It has active chemical properties and many unique performances.
Looking at its chemical activity, its properties are special due to the presence of fluorine atoms and bromine atoms in the molecule. Fluorine atoms have strong electronegativity, which can change the electron cloud distribution of molecules and enhance the stability and reactivity of molecules. Bromine atoms are good leaving groups and are prone to nucleophilic substitution reactions. In this reaction, nucleophiles are prone to attack carbon atoms connected to bromine, and bromine ions leave to form new compounds. This property makes 2% 2C5-difluorobenzyl bromide a key intermediate in the synthesis of complex organic molecules.
In addition to its physical properties, at room temperature, 2% 2C5-difluorobenzyl bromide is often a colorless to light yellow liquid with certain volatility. Its density is greater than that of water, and it is difficult to dissolve in water, but it is easily soluble in common organic solvents such as ethanol, ether, dichloromethane, etc. This solubility provides convenience for its organic synthesis operation. According to the needs of the reaction, a suitable solvent can be selected to facilitate the reaction.
However, it should be noted that 2% 2C5-difluorobenzyl bromide is toxic and corrosive. During operation, strict protective measures must be taken, such as protective clothing, gloves and goggles, to prevent contact with the skin and eyes. Inhalation of its volatile gases will also endanger health. And because of its active chemical properties, it needs to be properly stored during storage to avoid contact with oxidants, strong bases and other substances to prevent dangerous chemical reactions. In short, it is extremely important to understand the chemical properties of 2% 2C5-difluorobenzyl bromide for the rational and safe use of this compound.
What are the main uses of 2,5-dichlorophenethylamine?
2% 2C5-difluoroacetophenone has the following main uses:
First, in the field of pharmaceutical synthesis, this is a key intermediate. It can be used to create a variety of effective drugs, such as some antidepressants. Due to its unique chemical structure, it can give specific activities and properties to drug molecules, helping drugs to better act on human targets and achieve the purpose of treating diseases. In the process of drug development, it is used as a starting material, and through many chemical reaction steps, it gradually builds a complex drug molecular structure, making great contributions to human health.
Second, in the field of pesticide synthesis, 2% 2C5-difluoroacetophenone also plays an important role. It can be used to prepare high-efficiency and low-toxicity pesticide products. With the help of its participation in the reaction, compounds with special insecticidal, bactericidal or herbicidal properties can be generated. The prepared pesticides can precisely act on pests, and have significant protection effects on crops. At the same time, the adverse impact on the environment is minimized, and the efficient and sustainable development of agricultural production is effectively guaranteed.
Third, in the academic research and industrial production practice of organic synthetic chemistry, 2% 2C5-difluoroacetophenone is often used as an important synthetic building block. Due to the fact that the functional groups it contains are prone to various chemical reactions, such as nucleophilic addition and substitution, chemists can use this to construct organic compounds with diverse structures, greatly enriching the variety of organic compounds, expanding the development of organic synthetic chemistry and laying the foundation for the development of new materials and fine chemicals.
What are the precautions in the synthesis of 2,5-dichlorophenethylamine?
2% 2C5 -difluorobenzyl bromide in the process of organic synthesis, there are many things to pay attention to.
bear the brunt, and the safety must not be forgotten. This compound has considerable activity, and may have certain toxicity and irritation. When taking and handling, you must strictly follow safety regulations, wear protective clothing, goggles, gloves and other protective equipment, and work in a well-ventilated environment, such as a fume hood, to prevent its volatilization from affecting human health.
Furthermore, the control of reaction conditions is crucial. Temperature, time, and the proportion of reactants will all affect the process and yield of the reaction. For example, if you want to make the reaction proceed in the expected direction to obtain a good yield, you must precisely control the temperature. If the temperature is too high, or side reactions will occur, and the purity of the product will be damaged; if the temperature is too low, the reaction rate will be slow and time-consuming. At the same time, precise control of the proportion of reactants can make the reaction fully proceed, and avoid the trouble of excessive amounts of a reactant and subsequent separation.
Repeat, separation and purification are also important. After the reaction is completed, the product is often mixed with impurities such as unreacted raw materials and by-products. According to the physical and chemical properties of the product and impurities, appropriate separation and purification methods, such as distillation, recrystallization, column chromatography, etc., must be selected to obtain high-purity products.
In addition, storage should not be neglected. 2% 2C5-difluorobenzyl bromide should be stored in a cool, dry and ventilated place, away from fire sources and oxidants, and properly sealed to prevent it from deteriorating with air, moisture, etc., affecting subsequent use.
What is the market outlook for 2,5-dichlorophenethylamine?
In today's world, the market prospect of 2,5-difluoroacetophenone is related to many parties and is complex.
In the field of Guanfu Chemical Industry, 2,5-difluoroacetophenone has a wide range of uses. It is a key raw material in the synthesis of medicine. The development of many new drugs depends on its participation in the reaction to become a special drug and solve everyone's pain. Nowadays, the demand for medicine is increasing day by day, and the demand for its quality and quantity is also increasing. Therefore, in the corner of the pharmaceutical market, 2,5-difluoroacetophenone has a bright future and is expected to expand to a wider world with the advance of pharmaceutical technology.
As for the field of materials science, 2,5-difluoroacetophenone is also emerging. In the preparation of special materials, it can improve their properties and make them have excellent properties. Such as electronic materials, optical materials, etc., all have their place. Today's rapid technology, the demand for high-performance materials is eager, and 2,5-difluoroacetophenone has been given the opportunity to develop.
However, the market prospect does not depend solely on the demand side. The supply situation also affects its trend. The difficulty of its preparation process and the level of cost all affect the supply. If the process is complicated and the cost is high, the output is limited and the market expansion is also hindered. Although new processes have emerged today to reduce costs and increase output, it still takes time to improve and promote.
Furthermore, market competition is also an element that cannot be ignored. As its prospects gradually brighten, more and more entrants enter the market. Everyone strives for profits and applies their own means. Either seek to improve the process, or reduce the cost, or focus on quality improvement. Only those who stand out in the competition can take the lead in the market and enjoy the beauty of the prospect.
To sum up, although the market prospect of 2,5-difluoroacetophenone has potential, opportunities and challenges coexist. Industry players need to gain insight into the market, refine the process, and improve quality in order to seize the lead in the ever-changing market and open up a bright future.
What are the preparation methods of 2,5-dichlorophenethylamine?
To prepare 2,5-difluorobenzyl bromide, the methods are as follows:
First, start with 2,5-difluorotoluene and brominate it under light. In the reactor, set 2,5-difluorotoluene, remove oxygen through nitrogen, heat up to a suitable temperature, slowly add bromine dropwise, and at the same time irradiate with strong light. Bromine is active, and under light, it undergoes a free radical substitution reaction with the benzyl hydrogen of toluene to obtain 2,5-difluorobenzyl bromide. This reaction condition is mild, but it is necessary to strictly control the light intensity and bromine dropwise rate to prevent the formation of polybrominates.
Second, start with 2,5-difluorobenzoic acid, first reduce to 2,5-difluorobenzyl alcohol, and then react with hydrobromic acid. First react 2,5-difluorobenzyl acid with a strong reducing agent, such as lithium aluminum hydride, in anhydrous ether and other solvents, and carefully hydrolyze to obtain 2,5-difluorobenzyl alcohol. Next, mix 2,5-difluorobenzyl alcohol with hydrobromic acid, add an appropriate amount of sulfuric acid as a catalyst, and heat to reflux. In this process, the alcohol hydroxyl group is replaced by bromine atoms to obtain the target product. However, lithium aluminum hydride is dangerous, and the operation needs to be cautious, and there are many reaction steps.
Third, 2,5-difluorobenzaldehyde is used as the starting point, and 2,5-difluorobenzoic acid is obtained by haloform reaction, and then converted to 2,5-difluorobenzyl bromide as described above. 2,5-Difluorobenzaldehyde is co-heated with sodium hypohalite solution, and haloform reaction occurs to generate 2,5-difluorocarboxylate and haloform, and acidize to obtain 2,5-difluorobenzoic acid. Subsequent treatment is the same as the previous method. This route step is slightly complicated, but the raw material 2,5-difluorobenzaldehyde may be easily obtained.