2,5-Dichloro-Benzenesulfonylchlorid
Linshang Chemical
HS Code |
651654 |
Chemical Formula | C6H3Cl3O2S |
Molar Mass | 245.51 g/mol |
Appearance | Solid |
Color | White to off - white |
Odor | Pungent |
Solubility In Water | Reacts with water |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane |
Melting Point | 63 - 65 °C |
Density | 1.65 g/cm³ (estimated) |
Stability | Unstable in the presence of moisture |
As an accredited 2,5-Dichloro-Benzenesulfonylchlorid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 2,5 - dichloro - benzenesulfonylchlorid packaged in a sealed glass bottle. |
Storage | 2,5 - dichloro - benzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be stored in a tightly - sealed container to prevent moisture and air exposure, as it can react with water. Keep it separate from incompatible substances like bases, reducing agents, and reactive metals to avoid potential hazardous reactions. |
Shipping | 2,5 - dichloro - benzenesulfonyl chloride is a chemical. Shipping requires proper packaging in corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, ensuring secure transport to prevent spills and environmental or safety risks. |
Competitive 2,5-Dichloro-Benzenesulfonylchlorid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 2,5-Dichloro-Benzenesulfonylchlorid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Its appearance is usually a colorless to light yellow liquid, which is clear and transparent in appearance, and has no visible impurities. Smell, or have a special smell, but this smell may be different due to individual differences in olfaction.
When it comes to melting point, it is in a specific low temperature range, and the specific value depends on accurate measurement. The boiling point is relatively high, which determines that it exists in liquid form at room temperature and pressure.
In terms of density, there is a certain value, which is different from or different from water or other common solvents. In common organic solvents, it exhibits specific solubility, or it can be well miscible with some organic solvents, but poorly soluble with others.
Its vapor pressure has a corresponding value at a specific temperature, which is related to its equilibrium between the gas phase and the liquid phase. In addition, the refractive index is also one of its important physical properties, reflecting the refraction characteristics of light when passing through the substance.
Many physical properties are of great significance for its application in chemical industry, medicine and other fields. For example, according to the boiling point, suitable conditions can be set in the distillation separation process; by virtue of the difference in solubility, the effective extraction and purification of the substance from the mixture can be achieved. This all depends on the precise grasp and rational application of its physical properties.
is the first to bear the brunt, and this substance has strong reactivity. The acyl chloride group is extremely active and easily reacts with many nucleophiles. In case of alcohols, alcoholysis can occur rapidly to generate corresponding ester compounds. This reaction can be carried out smoothly under mild conditions, and the yield is quite high. In case of amines, aminolysis is prone to occur to form amides, which is a key step in the synthesis of a variety of nitrogen-containing compounds.
Furthermore, it is corrosive to a certain extent. Due to its active chemical properties, it has an erosive effect on some metals, organics, etc. During storage and use, special attention should be paid to the use of suitable materials to prevent the container from being corroded and leaking, causing safety accidents.
In addition, the fluorine atom of 2% 2C5-difluorobenzoyl chloride confers its unique properties. The large electronegativity of fluorine atoms changes the distribution of molecular electron clouds, which in turn affects its physical and chemical properties. Fluorinated compounds often have special stability, biological activity, etc., which lays the foundation for their application in the fields of medicine, pesticides, etc. In organic synthesis, the fluorine-containing structure fragment can be introduced by ingeniously designing reactions to prepare compounds with specific properties.
In chemical reactions, its reaction selectivity is also worthy of attention. Through reasonable selection of reaction conditions and reactants, precise control of the reaction check point can be achieved, and the target product can be obtained, which is of great significance for the synthesis of complex organic compounds.
However, due to its certain toxicity and irritation, strict safety procedures must be followed when using, and protective measures must be taken to ensure the safety of personnel and the environment from pollution.
First, 2% 2C5-difluorobenzoic acid is used as the starting material to react with thionyl chloride (SOCl ²). In this reaction, thionyl chloride is a chlorination reagent. Under suitable reaction conditions, such as heating and the presence of a catalyst, the carboxyl group (-COOH) of benzoic acid will be substituted with thionyl chloride, and the hydroxyl group (-OH) in the carboxyl group will be replaced by the chlorine atom (-Cl), resulting in the generation of 2% 2C5-difluorobenzoyl chloride, and the escape of sulfur dioxide (SO2O) and hydrogen chloride (HCl) gas at the same time. The chemical equation of the reaction can be expressed as: $C H F ³ O ³ + SOCl ³\ stackrel {catalyst, heated }{=\!=\!=} C H 🥰 F ³ ClO + SO ³ ↑ + HCl ↑ $. The advantages of this method are that the raw materials are relatively easy to obtain, the reaction steps are relatively simple, and the yield is relatively considerable.
Second, starting from 2% 2C5-difluorotoluene, 2% 2C5-difluorobenzoic acid is first oxidized, and then the target product is obtained by reacting with thionyl chloride as described above. The methyl group of toluene can be oxidized to a carboxyl group (-COOH) under suitable reaction conditions by suitable oxidants, such as potassium permanganate (KMnO), to generate 2% 2C5-difluorobenzoic acid. Then it can be synthesized by reacting with thionyl chloride to synthesize 2% 2C5-difluorobenzoyl chloride. Although this path has a little more steps, 2% 2C5-difluorotoluene is widely sourced and cost-controllable, and is also a commonly used synthesis strategy.
Third, the structure of 2% 2C5-difluorobenzoyl chloride is gradually constructed by a series of reaction steps such as nucleophilic substitution and functional group conversion with suitable halogenated aromatics as starting materials. This method requires precise control of the reaction conditions, and the selectivity of each step of the reaction is relatively high, but it also has certain application value for specific raw material sources and reaction systems.
All kinds of synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to carefully select the appropriate synthesis path according to the availability of raw materials, cost considerations, difficulty in controlling reaction conditions, and requirements for product purity.
In the field of medicine, its role is significant. It can be used to synthesize a variety of drugs, such as some antibacterial drugs and antiviral drugs. By reacting with other organic compounds, molecular structures with specific pharmacological activities are constructed, which makes great contributions to human health. For example, in the development of new antifungal drugs, 2% 2C5-difluorobenzoyl chloride is a key starting material, participating in complex reaction steps, and finally synthesizing drug molecules with high antifungal activity to help treat various fungal infections.
In the field of pesticides, it is also indispensable. It can be used to prepare a variety of high-efficiency and low-toxicity pesticides. For example, by synthesizing new insecticides, 2% 2C5-difluorobenzoyl chloride is integrated into the molecular structure of the pesticide through ingenious design of chemical reactions, giving the pesticide unique insecticidal properties, which can precisely attack pests, reduce the impact on the environment, ensure the healthy growth of crops, and improve the yield and quality of agricultural products.
In the field of materials science, 2% 2C5-difluorobenzoyl chloride also has outstanding performance. It can be used to synthesize polymer materials with special properties. By polymerizing with suitable monomers, polymer polymers with excellent thermal stability and chemical stability are prepared. These materials can be used in high-end fields such as aerospace, electronics and electrical appliances. For example, in the aerospace industry, synthesized polymer materials can be used to make aircraft parts, ensuring the safe and stable flight of aircraft in complex environments with their outstanding performance.
First, the protection must be thorough. When handling this object, you must wear special protective clothing, a protective mask, and wear corrosion-resistant gloves on your hands. Do not let your skin and eyes come into contact with it. Because of its strong corrosive nature, a little carelessness can burn your skin and damage your eyes.
Second, the operating environment needs to be well ventilated. It should be administered in a fume hood. If it is in a closed space, its volatile gas can easily cause air pollution. After inhalation, it may damage the respiratory tract and nervous system, causing cough, dizziness and other diseases.
Third, the method of use must be accurate. Measure with special equipment, strictly according to the amount required for experiment or production, and do not take more to prevent waste and risk. And the measurement action should be stable and accurate, and do not let it spill.
Fourth, storage must be cautious. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Do not mix with alkalis, alcohols and other substances to prevent violent reactions. Storage containers must also be tightly sealed to prevent leakage.
Fifth, emergency measures should be well known. In the event of a leak, leave the scene quickly until it is well ventilated. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there are large leaks, it is necessary to build a dike or dig a pit for containment, and transfer it to a special container with an explosion-proof pump. If you accidentally come into contact with the skin, rinse quickly with a large amount of flowing water and seek medical attention; if you splash into the eyes, lift the eyelids, and rinse with flowing water or normal saline, you also need to seek medical attention.
In short, the use of 2% 2C5-difluorobenzoyl chloride is related to safety, and there must be no slack. Every step of operation should be carried out according to the specifications.

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