2,5-Dichlorobenzene-1,4-Dicarboxylic Acid
Linshang Chemical
HS Code |
666691 |
Chemical Formula | C8H4Cl2O4 |
Molar Mass | 235.02 g/mol |
Appearance | White to off - white solid |
Melting Point | 295 - 298 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in some polar organic solvents like DMSO |
Pka1 | 2.95 |
Pka2 | 4.25 |
Density | 1.66 g/cm³ |
Crystal Structure | Orthorhombic |
Cas Number | 50446-44-1 |
As an accredited 2,5-Dichlorobenzene-1,4-Dicarboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 250g of 2,5 - dichlorobenzene - 1,4 - dicarboxylic acid packaged in a sealed plastic bag. |
Storage | 2,5 - dichlorobenzene - 1,4 - dicarboxylic acid should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances like strong oxidizing agents. Store it in a tightly closed container to prevent moisture absorption and potential contamination. Avoid exposure to sunlight. |
Shipping | 2,5 - dichlorobenzene - 1,4 - dicarboxylic acid is shipped in sealed, corrosion - resistant containers. These are carefully packed to prevent breakage during transit, following strict hazardous chemical shipping regulations. |
Competitive 2,5-Dichlorobenzene-1,4-Dicarboxylic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 2,5-Dichlorobenzene-1,4-Dicarboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of materials science, this compound is often a key monomer in the synthesis of high-performance polymers. By carefully regulating the polymerization reaction, it can be ingeniously integrated into the polymer backbone chain, which greatly enhances the thermal stability, mechanical properties and chemical stability of the material. For example, in aerospace engineering, the synthesized polymer materials may be used to make structural components of aircraft, helping them withstand extreme environments and stresses and ensuring flight safety.
In the field of medicinal chemistry, 2% 2C5-difluorobenzene-1% 2C4-dicarboxylic acid can be used as a key building block for the construction of new drug molecules. Due to its unique chemical structure, it may endow drugs with specific biological activities and pharmacological properties. Researchers can design highly effective drugs targeting specific disease targets, such as anti-tumor and anti-viral drugs, to contribute to human health and well-being.
Furthermore, in the field of organic synthetic chemistry, this compound, as an important synthesis intermediate, can participate in a variety of chemical reactions, assist in the synthesis of a series of complex and functional organic compounds, and promote the vigorous development of organic synthetic chemistry. It provides rich materials and possibilities for the development of innovative compounds.
Looking at its properties, it usually shows the appearance of white crystalline powder, which is easy to identify and easy to operate. Its melting point is about 300 degrees Celsius, and its melting point is quite high. This characteristic makes it easy to melt in high temperature environments and has good stability.
At the end of solubility, this compound has limited solubility in common organic solvents, such as methanol, ethanol, acetone, etc. However, it can be better dissolved in strong polar solvents, such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF). This difference in solubility is extremely critical in chemical preparation and separation and purification, and can be treated according to its characteristics.
In addition, the density of the substance is about 1.65 g/cm ³, which is relatively high. Compared with water, it sinks underwater. Its stability is quite good. Under normal environmental conditions, it is not easy to react with common components in the air, such as oxygen and carbon dioxide. However, under extreme conditions such as strong acids and bases, there may be chemical changes.
Furthermore, the sublimation of 2% 2C5-difluorobenzene-1% 2C4-dicarboxylic acid is negligible. Under normal temperature and pressure, it is difficult to see the appearance of sublimation, which makes its storage and transportation relatively convenient, without special consideration of the factors causing damage due to sublimation.
The physical properties of this compound are of great significance in many fields such as chemical synthesis and material preparation. It provides a basic basis for related research and production. Practitioners can make good use of it according to its characteristics.
2% 2C5-difluorobenzene-1% 2C4-dicarboxylic acid has different solubility in organic solvents. It is slightly soluble in common organic solvents such as ethanol and acetone; it is difficult to dissolve in polar strong solvents such as water. This solubility is due to the interaction between its own molecular structure and the solvent molecules.
The chemical activity of this compound is also very important. Its carboxyl group can neutralize with the base to form the corresponding carboxylate and water. If reacted with sodium hydroxide, 2% 2C5-difluorobenzene-1% 2C4-dicarboxylate sodium salt and water will be formed. At the same time, the carboxyl group can also participate in the esterification reaction, and react with alcohols under acid catalysis to form esters and water.
2% 2C5-difluorobenzene-1% 2C4-dicarboxylic acid The fluorine atom also gives it special chemical properties. The high electronegativity of fluorine atoms makes some reactivity of this compound different from that of unfluorinated analogs, and can participate in specific nucleophilic substitution reactions. It has important application value in the field of organic synthesis and can be used as a key intermediate for the preparation of more complex organic compounds.
Take an appropriate amount of p-xylene, place it in a reactor, and use an appropriate amount of fluorine-containing reagents, such as hydrogen fluoride, under specific temperature and pressure conditions, the p-xylene is fluorinated, and fluorine atoms are introduced at the 2nd and 5th positions of the benzene ring to obtain 2% 2C5-difluoro p-xylene. This reaction requires strict temperature control. If the temperature is too high, side reactions will easily occur, and if it is too low, the reaction rate will be slow.
Then, the obtained 2% 2C5-difluoro-p-xylene is heated and refluxed in a suitable solvent environment, such as an alkaline aqueous solution, with a strong oxidant, such as potassium permanganate. This step aims to oxidize two methyl groups of p-xylene to carboxyl groups to obtain 2% 2C5-difluorobenzene-1% 2C4-dicarboxylic acid. During the reaction process, it is necessary to pay attention to observe the color change and temperature change of the reaction to ensure that the reaction is fully carried out. After the reaction is completed, through cooling, filtration, washing, drying and other post-processing steps, a pure 2% 2C5-difluorobenzene-1% 2C4-dicarboxylic acid product can be obtained.
Another method is to use 2% 2C5-difluorobenzaldehyde as the starting material, first oxidize it with a suitable oxidant, such as Jones reagent, to 2% 2C5-difluorobenzoic acid, and then through a specific carboxylation reaction, the carboxyl group is introduced into the 4 position of the benzene ring to obtain the target product. In this way, the precise control of the reaction conditions at each step is crucial. Factors such as the pH, temperature, and time of the reaction have a significant impact on the yield and purity of the product. During the operation, relevant safety procedures must also be followed, and various chemical reagents must be properly handled to ensure the safety and efficiency of the preparation process.
First, the situation of supply and demand is related to the price. If there are many people who want it, but the supply is small, the price will increase; if the supply exceeds the demand, the price will drop automatically. Second, the manufacturing cost is also the key. Its preparation requires specific raw materials and processes. The price of raw materials fluctuates, or the cost increases due to the complexity of the process, which can change the price of the product. Third, the quality also affects the price. High purity, high quality, the price may be higher than usual.
Although the price range cannot be clearly stated, if you want to know the exact price of this compound, you can visit the chemical raw material trading platform, or consult the relevant chemical product suppliers, who may be able to tell the exact price. In this way, you can know the true price range in the market.

Scan to WhatsApp