2,5-Dichlorobenzeneacetonitrile
Linshang Chemical
HS Code |
350611 |
Chemical Formula | C8H3Cl2N |
Molecular Weight | 186.02 g/mol |
Appearance | White to off - white solid |
Melting Point | 52 - 56 °C |
Boiling Point | 275 - 277 °C |
Density | 1.42 g/cm³ (estimated) |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, acetone |
Vapor Pressure | Low vapor pressure |
Flash Point | 127 °C |
As an accredited 2,5-Dichlorobenzeneacetonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 2,5 - dichlorobenzeneacetonitrile packaged in a sealed plastic bottle. |
Storage | 2,5 - dichlorobenzeneacetonitrile should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and vapor release. Separate it from incompatible substances like acids and bases. Adhere to local safety regulations for proper storage. |
Shipping | 2,5 - dichlorobenzeneacetonitrile is shipped in sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper handling, storage, and transportation to prevent any environmental or safety risks. |
Competitive 2,5-Dichlorobenzeneacetonitrile prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 2,5-Dichlorobenzeneacetonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicine, this compound is often used as a key intermediate in the synthesis of many drugs. Due to the unique properties of fluorine atoms, it can change the physical and chemical properties of drug molecules, such as improving fat solubility, making it easier for drugs to penetrate biofilms and enhance their bioavailability. It can also enhance the interaction between drugs and targets, improve the activity and selectivity of drugs. Based on this, a variety of drugs such as antibacterial, antitumor, and antiviral can be synthesized, making great contributions to human health and well-being.
In the field of pesticides, 2% 2C5-difluorobenzyl acid is also of great value. With its unique chemical structure and the characteristics of fluorine atoms, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed. Such pesticides are highly selective to pests, can precisely attack target pests, while reducing the impact on non-target organisms, reducing environmental pollution, and meet the needs of the current development of green agriculture.
In the field of materials science, this compound can be used as an important raw material for the construction of special functional materials. Through chemical modification and polymerization, it can be introduced into polymer materials, giving materials such as weather resistance, chemical corrosion resistance, and special optical and electrical properties. In this way, it can be widely used in the modification of coatings, plastics, fibers and other materials to improve the performance and quality of materials and expand the application range of materials.
In summary, 2% 2C5-difluorobenzyl acid has significant uses in the fields of medicine, pesticides and materials science due to its unique chemical structure and fluorine atomic properties, and is of great significance to promote the development of related industries.
** Using 2% 2C5-difluorotoluene as raw material **:
Can be prepared by side chain chlorination reaction. Free radical substitution reaction of 2% 2C5-difluorotoluene with chlorine gas in the presence of light or initiator. The process is similar to a chain change triggered by a spark in the dark night. The chlorine molecules are homogenized into chlorine radicals under the action of light or initiators. The active chlorine radicals attack the hydrogen atoms on the 2% 2C5-difluorotoluene side chain methyl group to generate benzyl radicals. The benzyl radicals then react with chlorine to obtain 2% 2C5-difluorobenzyl chloride. This reaction condition is relatively mild and the operation is relatively simple, but the reaction temperature and the amount of chlorine gas introduced need to be precisely controlled, otherwise it is easy to produce polychlorinated by-products.
** Using 2% 2C5-difluorobenzoic acid as raw material **:
First reduce 2% 2C5-difluorobenzoic acid to 2% 2C5-difluorobenzyl alcohol, and choose a suitable reducing agent, such as sodium borohydride-zinc chloride system. This step is like turning the "mountain" into "flat ground" and converting the carboxyl group into a hydroxyl group. Then, 2% 2C5-difluorobenzyl alcohol reacts with chlorinated reagents, such as sulfoxide chloride and phosphorus trichloride, to achieve the replacement of the hydroxyl group by the chlorine atom to generate 2% 2C5-difluorobenzyl chloride. This path has a little more steps, but it can ensure higher product purity, requires high reaction equipment and operation, and some reagents have certain toxicity and corrosiveness, so careful operation is required.
** Using 2% 2C5-difluorobenzaldehyde as raw material **:
First, 2% 2C5-difluorobenzaldehyde is converted into 2% 2C5-difluorobenzyl alcohol by reduction reaction, and the subsequent steps are consistent with the process of using 2% 2C5-difluorobenzyl acid as raw material to obtain 2% 2C5-difluorobenzyl alcohol. The starting material of this route, 2% 2C5-difluorobenzaldehyde, is relatively easy to obtain, but there are many reaction steps, and the reaction conditions of each step need to be carefully controlled to improve the yield and purity of the product.
Looking at its physical properties, at room temperature and pressure, it is mostly colorless to light yellow liquid, or a crystalline solid, depending on its specific purity and environmental conditions. Its melting point and boiling point vary due to the presence of fluorine atoms in the molecular structure. Fluorine atoms have high electronegativity, which can strengthen intermolecular forces, resulting in higher melting points and boiling points than conventional similar compounds. For example, compared with similar benzyl acids without fluorine substitution, their boiling point may increase by tens of degrees Celsius. Its density is greater than that of water, and it has good solubility in organic solvents. For example, it can be miscible with common organic solvents such as ethanol, ethyl ether, and dichloromethane in any ratio. Due to the principle of similar miscibility, its organic structure is compatible with the structure of organic solvents.
When it comes to chemical properties, the benzyl group in the compound has certain reactivity. The benzene ring can undergo electrophilic substitution reaction, such as under the action of suitable catalysts, it can react with bromine, nitric acid and other reagents, and introduce a substituent at a specific position in the benzene ring. The acidity of the carboxyl group makes it possible to neutralize and react with bases to form corresponding carboxylates. In particular, the fluorine atom in the molecule gives it Fluorine atoms can enhance the oxidation resistance and corrosion resistance of molecules. At the same time, under certain specific reaction conditions, they can participate in the reaction as a leaving group and open a variety of chemical transformation pathways.
2% 2C5 -difluorobenzyl acid is widely used in the fields of medicine and pesticides. In the field of medicine, due to the unique influence of fluorine atoms on the metabolism and activity of drug molecules, it can be used as raw materials to synthesize drugs with unique pharmacological activities; in the field of pesticides, it can be used to prepare high-efficiency, low-toxicity and environmentally friendly pesticides, which can contribute to agricultural pest control.
First, when storing, it should be placed in a cool, dry and well-ventilated place. Because it may be more sensitive to humidity and temperature, high temperature and humid environment are prone to chemical reactions, resulting in damage to quality. This is just like an ancient treasure, it must choose a dry and cool place to prevent it from spoiling and deteriorating.
Second, it should be stored separately from oxidants, acids, bases and other substances. These substances may react chemically with 2% 2C5-difluorophenylacetic acid, causing danger. Just like the ancients kept things, water and fire different devices to prevent accidents.
Third, the storage area should be equipped with suitable materials for containing and handling leaks. If a leak occurs, it can be properly handled in time to avoid greater harm. This includes sand buckets, felt cloth, etc., to deal with sudden leaks.
Fourth, during transportation, ensure that the container is sealed to prevent leakage. The container must be sturdy and durable, able to withstand bumps and vibrations during transportation. Just like a long-distance load, it must be firmly equipped to keep it intact.
Fifth, the transportation vehicle should be equipped with corresponding fire equipment and leakage emergency treatment equipment. In case of an accident, it can be responded to in time to reduce losses. This is like marching to war, necessary weapons and rescue tools.
Sixth, transportation personnel need to be professionally trained to be familiar with the characteristics and emergency treatment methods of 2% 2C5-difluorophenylacetic acid. In this way, in case of emergencies, they can remain calm and deal with them properly. Just like craftsmen who are familiar with skills, they can deal with various problems.
If this thing is released indiscriminately in the environment, it may cause environmental pollution. Its chemical properties are relatively stable or difficult to degrade naturally, and it accumulates in soil and water bodies, which in turn affects the balance of the ecosystem. For example, it may affect the activity of soil microorganisms, damage soil fertility and hinder crop growth; in water bodies, it may affect the survival and reproduction of aquatic organisms, resulting in biodiversity loss.
As for human health, this thing may be ingested by the respiratory tract, skin contact or diet. If it enters the human body, it may interfere with the normal physiological functions of the human body. Modern research may show that such fluorinated organic compounds may affect the human endocrine system, similar to the ancient yin and yang imbalance, causing hormone secretion disorders, and affecting many physiological processes such as growth and development, metabolism, etc. Or it may have potential harm to the nervous system, making people prone to dizziness, fatigue, and memory loss, just like the ancient qi and blood, and spiritual consciousness disturbed. And this thing may have the risk of carcinogenesis and teratogenesis, although it is not completely conclusive, it must not be ignored. It is like walking on thin ice in the abyss to prevent problems before they occur. Therefore, the use and discharge of 2% 2C5-difluorophenylacetic acid should be handled with caution to protect the environment and human health.

Scan to WhatsApp