Linshang Chemical
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2,5-Dichlorobenzeneboronic Acid
Linshang Chemical
|
HS Code |
879023 |
| Chemical Formula | C6H5BCl2O2 |
| Molar Mass | 190.82 g/mol |
| Appearance | White to off - white solid |
| Melting Point | 146 - 150 °C |
| Solubility In Water | Slightly soluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, toluene |
| Pka | Around 8 - 9 |
| Boiling Point | Decomposes before boiling |
| Stability | Stable under normal conditions, but moisture - sensitive |
As an accredited 2,5-Dichlorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 2,5 - dichlorobenzeneboronic Acid in a sealed, chemical - resistant plastic bag. |
| Storage | 2,5 - Dichlorobenzeneboronic acid should be stored in a cool, dry place away from heat and ignition sources. Keep it in a tightly - sealed container to prevent moisture absorption and contact with air, which could lead to degradation. Store it separately from incompatible substances like strong oxidizing agents and bases to avoid potential chemical reactions. |
| Shipping | 2,5 - dichlorobenzeneboronic Acid is shipped in well - sealed containers, often within a protective packaging. Shipment adheres to chemical transport regulations to prevent spills, ensuring safe transit to its destination. |
Competitive 2,5-Dichlorobenzeneboronic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,5-Dichlorobenzeneboronic Acid in China?
As a trusted 2,5-Dichlorobenzeneboronic Acid manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2,5-Dichlorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2,5-dichlorophenylboronic acid?
2% 2C5-dioxybenzoic acid has fair and reactive properties. It is a white crystalline solid with the general properties of acid and can combine with alkali phases to form salt and water. It is slightly soluble in water, but slightly soluble in organic solvents such as ethanol and ether.
Among its chemical activities, the carboxyl group is the main part of the reaction. It can react with alcohols through esterification to produce corresponding esters. This reaction requires acid as a catalyst and heating to promote it. And it can interact with metal oxides and hydroxides to form metal carboxylates, which are the genus of acid-base neutralization.
In the field of organic synthesis, 2% 2C5-dioxybenzoic acid is the important raw material. The reactivity of its carboxyl group can be used to introduce other functional groups to produce a variety of organic compounds. Because of the dioxy part in its structure, it endows the molecule with a specific electron cloud distribution and spatial conformation, which affects its reactivity and physical properties.
And because of its certain stability, it can be stored under suitable conditions and is not easy to decompose. In case of strong oxidizing agents, reducing agents or in extreme acid-base environments, its structure may change, causing chemical changes. The characteristics of this substance make it have potential for application in chemical, pharmaceutical, materials and other fields, and are important for organic chemistry research and practical production.
Among its chemical activities, the carboxyl group is the main part of the reaction. It can react with alcohols through esterification to produce corresponding esters. This reaction requires acid as a catalyst and heating to promote it. And it can interact with metal oxides and hydroxides to form metal carboxylates, which are the genus of acid-base neutralization.
In the field of organic synthesis, 2% 2C5-dioxybenzoic acid is the important raw material. The reactivity of its carboxyl group can be used to introduce other functional groups to produce a variety of organic compounds. Because of the dioxy part in its structure, it endows the molecule with a specific electron cloud distribution and spatial conformation, which affects its reactivity and physical properties.
And because of its certain stability, it can be stored under suitable conditions and is not easy to decompose. In case of strong oxidizing agents, reducing agents or in extreme acid-base environments, its structure may change, causing chemical changes. The characteristics of this substance make it have potential for application in chemical, pharmaceutical, materials and other fields, and are important for organic chemistry research and practical production.
What are the main uses of 2,5-dichlorophenylboronic acid?
2% 2C5-dihydroxybenzoic acid, that is, 2,5-dihydroxybenzoic acid, its main uses are as follows:
This substance is used in medicine and has a wide range of uses. It can be used as a synthetic raw material for many drugs and is often used in the preparation of antibacterial, anti-inflammatory and other drugs. Due to its chemical structure, it can be combined with specific targets in organisms to exert corresponding pharmacological effects and help relieve diseases and heal diseases.
In the dye industry, it also plays an important role. Its molecular structure can be modified by specific chemicals, giving it good dyeing properties. It can be used to synthesize all kinds of dyes with bright colors and good fastness. It is widely used in dyeing processes such as textiles and leather to make fabrics and leather show rich colors and enhance their aesthetics and commercial value.
In the field of cosmetics, it is also used. With its special chemical properties, it has a certain antioxidant effect, can resist free radical damage to the skin, and delay skin aging, so it is often added to skin care products to care for skin health and maintain skin youthfulness.
In addition, in the field of fine chemicals, it is an important organic synthesis intermediate. Through a series of chemical reactions, many fine chemicals with special properties can be derived, which can be used in many industries such as electronics and coatings to help improve the performance and quality of products in various industries.
This substance is used in medicine and has a wide range of uses. It can be used as a synthetic raw material for many drugs and is often used in the preparation of antibacterial, anti-inflammatory and other drugs. Due to its chemical structure, it can be combined with specific targets in organisms to exert corresponding pharmacological effects and help relieve diseases and heal diseases.
In the dye industry, it also plays an important role. Its molecular structure can be modified by specific chemicals, giving it good dyeing properties. It can be used to synthesize all kinds of dyes with bright colors and good fastness. It is widely used in dyeing processes such as textiles and leather to make fabrics and leather show rich colors and enhance their aesthetics and commercial value.
In the field of cosmetics, it is also used. With its special chemical properties, it has a certain antioxidant effect, can resist free radical damage to the skin, and delay skin aging, so it is often added to skin care products to care for skin health and maintain skin youthfulness.
In addition, in the field of fine chemicals, it is an important organic synthesis intermediate. Through a series of chemical reactions, many fine chemicals with special properties can be derived, which can be used in many industries such as electronics and coatings to help improve the performance and quality of products in various industries.
What are the synthesis methods of 2,5-dichlorophenylboronic acid?
2% 2C5-difluorobenzoic acid is a key intermediate in organic synthesis and has a wide range of uses in the fields of medicine, pesticides and materials. Its synthesis methods are diverse, and the following are described in detail:
1. ** Aromatic nucleophilic substitution method **: 2,5-dichlorobenzoic acid is used as a starting material and reacts with potassium fluoride in a high-boiling organic solvent such as N-methylpyrrolidone (NMP) at high temperature and under the action of a phase transfer catalyst. The principle of this reaction is that fluorine ions nucleophilic replace chlorine atoms to form the target product. The reaction formula is as follows:
2,5-dichlorobenzoic acid + KF $\ xrightarrow [] {NMP, high temperature, phase transfer catalyst} $2,5-difluorobenzoic acid + KCl
The advantage of this method is that the raw material is easy to obtain, the disadvantage is that the reaction conditions are harsh, high temperature and specific organic solvents are required, and the cost of the phase transfer catalyst is high.
2. ** Diazo fluoridation method **: First, 2,5-diaminobenzoic acid is reacted by diazotization to form a diazonium salt, and then reacts with fluoroborate acid to form a fluoroborate, which is decomposed by heating to obtain 2,5-difluorobenzoic acid. The specific steps are:
2,5 -diaminobenzoic acid + HNO ³ (low temperature) → diazonium salt
diazonium salt + HBF → fluoroborate
fluoroborate $\ xrightarrow [] {heating} $2,5 -difluorobenzoic acid + BF ↑ + N ³ ↑
The advantage of this method is that the reaction selectivity is good, and the disadvantage is that the steps are complicated and a large amount of waste gas is generated, which is not friendly to the environment.
3. ** Halogenated aromatic hydrocarbon carbonylation method **: Using 2,5-difluorobromobenzene as raw material, under the action of carbon monoxide atmosphere and transition metal catalyst, such as palladium catalyst, carbonylation reaction occurs with carbon monoxide and water or alcohol. If reacted with water, 2,5-difluorobenzoic acid is formed; if reacted with alcohol, it is formed into an ester, and then hydrolyzed to obtain an acid. The reaction formula is as follows:
2,5-difluorobrobenzene + CO + H2O O $\ xrightarrow [] {palladium catalyst} $2,5-difluorobenzoic acid + HBr
This method has high atomic utilization, but carbon monoxide is a toxic gas, which requires strict reaction equipment and operation.
4. ** Electrochemical fluorination method **: In a specific electrolyte solution, a carboxylic acid derivative containing a benzene ring is used as a raw material, and fluorine atoms are directly introduced into the benzene ring through an electrochemical fluorination reaction. This method is green and environmentally friendly, does not require the use of toxic and harmful fluorination reagents, but requires high equipment, and the reaction conditions are difficult to control.
1. ** Aromatic nucleophilic substitution method **: 2,5-dichlorobenzoic acid is used as a starting material and reacts with potassium fluoride in a high-boiling organic solvent such as N-methylpyrrolidone (NMP) at high temperature and under the action of a phase transfer catalyst. The principle of this reaction is that fluorine ions nucleophilic replace chlorine atoms to form the target product. The reaction formula is as follows:
2,5-dichlorobenzoic acid + KF $\ xrightarrow [] {NMP, high temperature, phase transfer catalyst} $2,5-difluorobenzoic acid + KCl
The advantage of this method is that the raw material is easy to obtain, the disadvantage is that the reaction conditions are harsh, high temperature and specific organic solvents are required, and the cost of the phase transfer catalyst is high.
2. ** Diazo fluoridation method **: First, 2,5-diaminobenzoic acid is reacted by diazotization to form a diazonium salt, and then reacts with fluoroborate acid to form a fluoroborate, which is decomposed by heating to obtain 2,5-difluorobenzoic acid. The specific steps are:
2,5 -diaminobenzoic acid + HNO ³ (low temperature) → diazonium salt
diazonium salt + HBF → fluoroborate
fluoroborate $\ xrightarrow [] {heating} $2,5 -difluorobenzoic acid + BF ↑ + N ³ ↑
The advantage of this method is that the reaction selectivity is good, and the disadvantage is that the steps are complicated and a large amount of waste gas is generated, which is not friendly to the environment.
3. ** Halogenated aromatic hydrocarbon carbonylation method **: Using 2,5-difluorobromobenzene as raw material, under the action of carbon monoxide atmosphere and transition metal catalyst, such as palladium catalyst, carbonylation reaction occurs with carbon monoxide and water or alcohol. If reacted with water, 2,5-difluorobenzoic acid is formed; if reacted with alcohol, it is formed into an ester, and then hydrolyzed to obtain an acid. The reaction formula is as follows:
2,5-difluorobrobenzene + CO + H2O O $\ xrightarrow [] {palladium catalyst} $2,5-difluorobenzoic acid + HBr
This method has high atomic utilization, but carbon monoxide is a toxic gas, which requires strict reaction equipment and operation.
4. ** Electrochemical fluorination method **: In a specific electrolyte solution, a carboxylic acid derivative containing a benzene ring is used as a raw material, and fluorine atoms are directly introduced into the benzene ring through an electrochemical fluorination reaction. This method is green and environmentally friendly, does not require the use of toxic and harmful fluorination reagents, but requires high equipment, and the reaction conditions are difficult to control.
What should be paid attention to when storing and transporting 2,5-dichlorophenylboronic acid?
2% 2C5-difluorobenzoic acid is a chemical substance. When storing and transporting it, many matters must not be ignored.
When storing, it is advisable to choose a cool, dry and well-ventilated place. This is because the substance may be sensitive to temperature and humidity, and the temperature is high and wet, which may cause its properties to change or cause chemical reactions. And it must be kept away from fire and heat sources. It may be flammable or dangerous in case of fire. It should be stored separately from oxidants, alkalis, etc. to prevent mutual reaction and cause harm.
When transporting, be sure to abide by relevant regulations and standards. The packaging must be tight to ensure that there is no risk of leakage on the way. When loading and unloading, it should also be handled with care to avoid shock and pressure, which may cause damage to the packaging. Transportation vehicles should also be equipped with corresponding fire and leakage emergency treatment equipment, so that they can respond in time if something happens.
The escort must be familiar with the characteristics of the substance and emergency treatment methods. Check the packaging regularly on the way, and if there is any leakage, deal with it quickly according to the established policies. In this way, the safety of 2% 2C5-difluorobenzoic acid during storage and transportation can be guaranteed, and accidents can be avoided.
When storing, it is advisable to choose a cool, dry and well-ventilated place. This is because the substance may be sensitive to temperature and humidity, and the temperature is high and wet, which may cause its properties to change or cause chemical reactions. And it must be kept away from fire and heat sources. It may be flammable or dangerous in case of fire. It should be stored separately from oxidants, alkalis, etc. to prevent mutual reaction and cause harm.
When transporting, be sure to abide by relevant regulations and standards. The packaging must be tight to ensure that there is no risk of leakage on the way. When loading and unloading, it should also be handled with care to avoid shock and pressure, which may cause damage to the packaging. Transportation vehicles should also be equipped with corresponding fire and leakage emergency treatment equipment, so that they can respond in time if something happens.
The escort must be familiar with the characteristics of the substance and emergency treatment methods. Check the packaging regularly on the way, and if there is any leakage, deal with it quickly according to the established policies. In this way, the safety of 2% 2C5-difluorobenzoic acid during storage and transportation can be guaranteed, and accidents can be avoided.
What is the approximate market price of 2,5-dichlorophenylboronic acid?
2% 2C5-difluorobenzoic acid, an important organic compound, is widely used in many fields such as medicine, pesticides and materials. As for its market price, it is difficult to accurately determine, because it is influenced by many factors.
The first to bear the brunt, the market supply and demand have a huge impact on its price. If the market demand for 2% 2C5-difluorobenzoic acid is strong, and the supply is relatively short, the price will rise; conversely, if the market oversupply, the price is likely to fall.
Furthermore, the cost of raw materials is also a key factor. The price fluctuations of the raw materials required to synthesize 2% 2C5-difluorobenzoic acid will be directly transmitted to the final product. Raw material prices rise, production costs increase, and product prices will also increase.
The difficulty of the production process and the level of production efficiency will also have an impact on prices. Advanced and efficient production processes can reduce production costs, thus making product prices more competitive; if the production process is complex and inefficient, costs are bound to increase and prices will remain high.
In addition, 2% 2C5-difluorobenzoic acid produced by different manufacturers will vary in price due to product quality and purity. High-purity products are usually more expensive.
Overall, the current market price of 2% 2C5-difluorobenzoic acid is roughly in the range of hundreds to thousands of yuan per kilogram. However, this is only a general range, and the actual price depends on the specific market conditions and transaction details. For the exact price, please consult the relevant manufacturers, distributors, or refer to the quotations of professional chemical product trading platforms.
The first to bear the brunt, the market supply and demand have a huge impact on its price. If the market demand for 2% 2C5-difluorobenzoic acid is strong, and the supply is relatively short, the price will rise; conversely, if the market oversupply, the price is likely to fall.
Furthermore, the cost of raw materials is also a key factor. The price fluctuations of the raw materials required to synthesize 2% 2C5-difluorobenzoic acid will be directly transmitted to the final product. Raw material prices rise, production costs increase, and product prices will also increase.
The difficulty of the production process and the level of production efficiency will also have an impact on prices. Advanced and efficient production processes can reduce production costs, thus making product prices more competitive; if the production process is complex and inefficient, costs are bound to increase and prices will remain high.
In addition, 2% 2C5-difluorobenzoic acid produced by different manufacturers will vary in price due to product quality and purity. High-purity products are usually more expensive.
Overall, the current market price of 2% 2C5-difluorobenzoic acid is roughly in the range of hundreds to thousands of yuan per kilogram. However, this is only a general range, and the actual price depends on the specific market conditions and transaction details. For the exact price, please consult the relevant manufacturers, distributors, or refer to the quotations of professional chemical product trading platforms.
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