Linshang Chemical
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2,5-Dichlorobenzenesulfonyl Chloride
Linshang Chemical
|
HS Code |
522656 |
| Chemical Formula | C6H3Cl3O2S |
| Molar Mass | 245.51 g/mol |
| Appearance | Colorless to light yellow solid |
| Odor | Pungent |
| Melting Point | 46 - 48 °C |
| Boiling Point | 154 - 156 °C (12 mmHg) |
| Density | 1.67 g/cm³ |
| Solubility In Water | Reacts with water |
| Solubility In Organic Solvents | Soluble in many organic solvents |
| Flash Point | 110 °C |
| Hazard Class | Corrosive |
| Cas Number | 88-43-7 |
As an accredited 2,5-Dichlorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 2,5 - dichlorobenzenesulfonyl chloride packaged in a sealed, corrosion - resistant container. |
| Storage | 2,5 - dichlorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It should be kept in a tightly - sealed container to prevent moisture ingress, as it is reactive with water. Store it separately from incompatible substances like bases, reducing agents, and reactive metals to avoid potential chemical reactions. |
| Shipping | 2,5 - dichlorobenzenesulfonyl chloride is a hazardous chemical. It should be shipped in accordance with strict regulations. Packed in suitable corrosion - resistant containers, transported by carriers approved for hazardous chemicals, ensuring proper labeling and documentation. |
Competitive 2,5-Dichlorobenzenesulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,5-Dichlorobenzenesulfonyl Chloride in China?
As a trusted 2,5-Dichlorobenzenesulfonyl Chloride manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2,5-Dichlorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2,5-dichlorobenzenesulfonyl chloride?
2% 2C5-difluorobenzoyl chloride is a crucial raw material in organic synthesis and is widely used in many fields. Its main uses are as follows:
** 1. Pharmaceutical synthesis field **
In the preparation of medicine, 2% 2C5-difluorobenzoyl chloride plays a key role. It can be used as a key intermediate for the synthesis of a variety of specific drugs. For example, some targeted therapeutic drugs for specific diseases require 2% 2C5-difluorobenzoyl chloride to participate in the reaction to construct a special chemical structure to give the drug precise therapeutic effect. Due to its unique chemical properties, it can react specifically with other organic compounds to generate molecules with biological activity, making outstanding contributions to human health.
** Second, pesticide research and development **
In the field of pesticides, this compound has a wide range of uses. It can be used to create new pesticides because of its good chemical activity, which can be combined with other substances to prepare pesticide products with efficient killing or inhibition of pests. And such pesticides based on the synthesis of 2% 2C5-difluorobenzoyl chloride often have environmentally friendly characteristics. Compared with traditional pesticides, they are less harmful to the ecological environment and have low residues. They can effectively protect the growth of crops while reducing the negative impact on the environment.
** III. Materials Science **
In the field of materials science, 2% 2C5-difluorobenzoyl chloride is also useful. It can participate in the synthesis process of polymer materials, and through clever design and reaction, it can be introduced into the polymer structure, thereby changing the properties of the material. Such as improving the stability, heat resistance, and chemical corrosion resistance of the material. These modified materials have important application value in high-end fields such as aerospace and electronics, and can meet the strict requirements of material properties in special environments.
In summary, 2% 2C5-difluorobenzoyl chloride, with its unique chemical properties, plays an indispensable role in many fields such as medicine, pesticides, and materials science, and promotes technological progress and industrial development in various fields.
** 1. Pharmaceutical synthesis field **
In the preparation of medicine, 2% 2C5-difluorobenzoyl chloride plays a key role. It can be used as a key intermediate for the synthesis of a variety of specific drugs. For example, some targeted therapeutic drugs for specific diseases require 2% 2C5-difluorobenzoyl chloride to participate in the reaction to construct a special chemical structure to give the drug precise therapeutic effect. Due to its unique chemical properties, it can react specifically with other organic compounds to generate molecules with biological activity, making outstanding contributions to human health.
** Second, pesticide research and development **
In the field of pesticides, this compound has a wide range of uses. It can be used to create new pesticides because of its good chemical activity, which can be combined with other substances to prepare pesticide products with efficient killing or inhibition of pests. And such pesticides based on the synthesis of 2% 2C5-difluorobenzoyl chloride often have environmentally friendly characteristics. Compared with traditional pesticides, they are less harmful to the ecological environment and have low residues. They can effectively protect the growth of crops while reducing the negative impact on the environment.
** III. Materials Science **
In the field of materials science, 2% 2C5-difluorobenzoyl chloride is also useful. It can participate in the synthesis process of polymer materials, and through clever design and reaction, it can be introduced into the polymer structure, thereby changing the properties of the material. Such as improving the stability, heat resistance, and chemical corrosion resistance of the material. These modified materials have important application value in high-end fields such as aerospace and electronics, and can meet the strict requirements of material properties in special environments.
In summary, 2% 2C5-difluorobenzoyl chloride, with its unique chemical properties, plays an indispensable role in many fields such as medicine, pesticides, and materials science, and promotes technological progress and industrial development in various fields.
What are the physical properties of 2,5-dichlorobenzenesulfonyl chloride?
2% 2C5-difluorobenzoyl chloride is an important compound in organic chemistry. Its physical properties are quite unique and it has a variety of uses.
Looking at its properties, under room temperature and pressure, 2% 2C5-difluorobenzoyl chloride is in a colorless to light yellow liquid state, with a clear appearance and occasionally a little irritating color. This substance has a pungent odor and is volatile in the air. The volatile gas is highly irritating and can cause damage to the eyes, respiratory mucosa, etc. It needs to be paid more attention when operating.
When it comes to melting point and boiling point, the melting point is about -34 ° C, and the boiling point is between 190 ° C and 192 ° C. Such melting and boiling point characteristics keep it in a liquid state at room temperature, and it is easier to gasify under heating and other conditions. This characteristic is of great significance in chemical operations such as separation, purification, and control of reaction conditions. It can be adjusted by temperature to achieve its phase change for the expected experimental or production purposes.
2% 2C5-difluorobenzoyl chloride has a density of about 1.45g/cm ³, which is heavier than water. If accidentally mixed with water, it will sink to the bottom. And it is insoluble in water, but soluble in most organic solvents such as ether, dichloromethane, and chloroform. This solubility characteristic is extremely critical in organic synthesis. Researchers can choose suitable organic solvents to dissolve according to the reaction requirements, so that they can participate in various chemical reactions and lay the foundation for the construction of complex organic molecular structures.
In addition, 2% 2C5-difluorobenzoyl chloride contains active acid chloride groups, which are chemically active and easily react with nucleophiles such as alcohols and amines to generate corresponding esters and amides. It is widely used in the synthesis of fine chemical products such as medicines, pesticides, and dyes. It is an important intermediate for the preparation of a variety of high value-added chemicals.
Looking at its properties, under room temperature and pressure, 2% 2C5-difluorobenzoyl chloride is in a colorless to light yellow liquid state, with a clear appearance and occasionally a little irritating color. This substance has a pungent odor and is volatile in the air. The volatile gas is highly irritating and can cause damage to the eyes, respiratory mucosa, etc. It needs to be paid more attention when operating.
When it comes to melting point and boiling point, the melting point is about -34 ° C, and the boiling point is between 190 ° C and 192 ° C. Such melting and boiling point characteristics keep it in a liquid state at room temperature, and it is easier to gasify under heating and other conditions. This characteristic is of great significance in chemical operations such as separation, purification, and control of reaction conditions. It can be adjusted by temperature to achieve its phase change for the expected experimental or production purposes.
2% 2C5-difluorobenzoyl chloride has a density of about 1.45g/cm ³, which is heavier than water. If accidentally mixed with water, it will sink to the bottom. And it is insoluble in water, but soluble in most organic solvents such as ether, dichloromethane, and chloroform. This solubility characteristic is extremely critical in organic synthesis. Researchers can choose suitable organic solvents to dissolve according to the reaction requirements, so that they can participate in various chemical reactions and lay the foundation for the construction of complex organic molecular structures.
In addition, 2% 2C5-difluorobenzoyl chloride contains active acid chloride groups, which are chemically active and easily react with nucleophiles such as alcohols and amines to generate corresponding esters and amides. It is widely used in the synthesis of fine chemical products such as medicines, pesticides, and dyes. It is an important intermediate for the preparation of a variety of high value-added chemicals.
Is the chemical properties of 2,5-dichlorobenzenesulfonyl chloride stable?
The chemical properties of 2% 2C5-difluorobenzoyl chloride are relatively stable. However, this does not mean that when it is absolutely inactive, it covers the chemical substance, and its properties often vary depending on the environment and the agent it encounters.
Under normal temperature and pressure, 2% 2C5-difluorobenzoyl chloride can be stable. In its molecular structure, the conjugate system of the benzene ring gives it a certain stability, and the introduction of fluorine atoms, although it has strong electronegativity, changes the distribution of the molecular electron cloud, but it has not caused it to be easily decomposed or reacted.
When it encounters water, 2% 2C5-difluorobenzoyl chloride is very active. Water can cause it to hydrolyze to produce 2% 2C5-difluorobenzoic acid and hydrogen chloride. The rate of hydrolysis is related to the amount of water, temperature and the environment of the reaction. In the environment of high temperature and water, the hydrolysis rate is even faster.
In case of alcohols, 2% 2C5-difluorobenzoyl chloride can also react to form esters. This reaction depends on the catalyst or suitable temperature and pressure conditions. The structure of the alcohol is different, and the difficulty and rate of the reaction are also different.
In an alkaline environment, 2% 2C5-difluorobenzoyl chloride is also unsafe. The base can promote its hydrolysis or react with the nucleophilic groups in the base, resulting in molecular structural changes. Therefore, the stability of 2% 2C5-difluorobenzoyl chloride can be said to be stable at room temperature and pressure without water and no special reagents. However, when exposed to water, alcohol, alkali, etc., its activity is obvious, and its structure changes and participates in various chemical reactions.
Under normal temperature and pressure, 2% 2C5-difluorobenzoyl chloride can be stable. In its molecular structure, the conjugate system of the benzene ring gives it a certain stability, and the introduction of fluorine atoms, although it has strong electronegativity, changes the distribution of the molecular electron cloud, but it has not caused it to be easily decomposed or reacted.
When it encounters water, 2% 2C5-difluorobenzoyl chloride is very active. Water can cause it to hydrolyze to produce 2% 2C5-difluorobenzoic acid and hydrogen chloride. The rate of hydrolysis is related to the amount of water, temperature and the environment of the reaction. In the environment of high temperature and water, the hydrolysis rate is even faster.
In case of alcohols, 2% 2C5-difluorobenzoyl chloride can also react to form esters. This reaction depends on the catalyst or suitable temperature and pressure conditions. The structure of the alcohol is different, and the difficulty and rate of the reaction are also different.
In an alkaline environment, 2% 2C5-difluorobenzoyl chloride is also unsafe. The base can promote its hydrolysis or react with the nucleophilic groups in the base, resulting in molecular structural changes. Therefore, the stability of 2% 2C5-difluorobenzoyl chloride can be said to be stable at room temperature and pressure without water and no special reagents. However, when exposed to water, alcohol, alkali, etc., its activity is obvious, and its structure changes and participates in various chemical reactions.
What is the preparation method of 2,5-dichlorobenzenesulfonyl chloride?
2% 2C5-difluorobenzoyl chloride, the preparation method is as follows:
First take 2,5-difluorobenzoic acid and place it in the reaction kettle, dissolve it with an appropriate amount of organic solvent such as dichloromethane and chloroform, and stir evenly to form a homogeneous solution. The choice of this organic solvent, depending on the reaction requirements and material characteristics, must have good solubility and stable chemical properties, and do not react adversely with reactants and products.
Then, slowly add chlorinated reagents, such as thionyl chloride, phosphorus trichloride or phosphorus pentachloride, etc. Taking thionyl chloride as an example, its reaction with benzoic acid is quite common. When adding thionyl chloride, it is appropriate to control the dripping speed and maintain a certain temperature. It is usually added dropwise at low temperature, such as 0-10 ° C, to prevent the reaction from being too violent. After the dropwise addition, gradually heat up to 40-80 ° C, and when the reaction number is refluxed. The control of this temperature and time is very important. If the temperature is too low, the reaction will be slow, and if it is too high, side reactions will easily occur. If the reaction is too short, the energy consumption will increase and the product may decompose.
During the reaction, the visible phenomenon is that the solution gradually boils and gas escapes. This is the sulfur dioxide, hydrogen chloride and other gases generated by the reaction. It must be captured with a suitable tail gas treatment device to prevent pollution of the environment.
After the reaction is completed, first distill under reduced pressure to remove the unreacted sulfoxide chloride and organic solvent. Then, the product is purified by distillation, and the distillate in a specific boiling point range can be collected to obtain a high purity of 2,5-difluorobenzoyl chloride. During distillation, precise temperature and pressure control are used to achieve the best separation effect.
During the preparation process, all details must be paid attention to. The proportion of materials, the temperature and time of the reaction, the treatment of the exhaust gas, and the purification process are all related to the purity and yield of the product, and should not be ignored.
First take 2,5-difluorobenzoic acid and place it in the reaction kettle, dissolve it with an appropriate amount of organic solvent such as dichloromethane and chloroform, and stir evenly to form a homogeneous solution. The choice of this organic solvent, depending on the reaction requirements and material characteristics, must have good solubility and stable chemical properties, and do not react adversely with reactants and products.
Then, slowly add chlorinated reagents, such as thionyl chloride, phosphorus trichloride or phosphorus pentachloride, etc. Taking thionyl chloride as an example, its reaction with benzoic acid is quite common. When adding thionyl chloride, it is appropriate to control the dripping speed and maintain a certain temperature. It is usually added dropwise at low temperature, such as 0-10 ° C, to prevent the reaction from being too violent. After the dropwise addition, gradually heat up to 40-80 ° C, and when the reaction number is refluxed. The control of this temperature and time is very important. If the temperature is too low, the reaction will be slow, and if it is too high, side reactions will easily occur. If the reaction is too short, the energy consumption will increase and the product may decompose.
During the reaction, the visible phenomenon is that the solution gradually boils and gas escapes. This is the sulfur dioxide, hydrogen chloride and other gases generated by the reaction. It must be captured with a suitable tail gas treatment device to prevent pollution of the environment.
After the reaction is completed, first distill under reduced pressure to remove the unreacted sulfoxide chloride and organic solvent. Then, the product is purified by distillation, and the distillate in a specific boiling point range can be collected to obtain a high purity of 2,5-difluorobenzoyl chloride. During distillation, precise temperature and pressure control are used to achieve the best separation effect.
During the preparation process, all details must be paid attention to. The proportion of materials, the temperature and time of the reaction, the treatment of the exhaust gas, and the purification process are all related to the purity and yield of the product, and should not be ignored.
What are the precautions for storing and transporting 2,5-dichlorobenzenesulfonyl chloride?
2% 2C5-difluorobenzoyl chloride is a chemical substance. During storage and transportation, the following rules should be followed:
First, when storing, choose a cool, dry and well-ventilated place. Because 2% 2C5-difluorobenzoyl chloride has a certain chemical activity, it is easy to chemically react in high temperature and humid environment, resulting in quality deterioration. And it should be kept away from fire and heat sources, because the substance is at risk of exposure to open flames, hot topics or combustion explosions.
Second, the storage container must be tightly sealed. 2% 2C5-difluorobenzoyl chloride is sensitive to water vapor, and contact with water can react violently to form harmful products. Therefore, glass bottles or metal drums lined with special anti-corrosion materials are commonly used for storage to prevent leakage and deterioration.
Third, during transportation, ensure that the container is stable and will not collide or pour. Because it is a dangerous chemical, once it leaks, it not only pollutes the environment, but also poses a threat to human health. Transportation vehicles also need to be equipped with corresponding emergency treatment equipment and protective equipment to deal with emergencies.
Fourth, storage and transportation should be strictly operated in accordance with regulations. Relevant personnel need to be professionally trained and familiar with the characteristics, hazards and emergency disposal methods of 2% 2C5-difluorobenzoyl chloride. At the same time, obvious warning signs should be set up in storage and transportation sites to indicate its danger. In conclusion, the storage and transportation of 2% 2C5-difluorobenzoyl chloride must be done with caution and strict safety regulations, so as to effectively avoid accidents and ensure the safety of personnel and the environment.
First, when storing, choose a cool, dry and well-ventilated place. Because 2% 2C5-difluorobenzoyl chloride has a certain chemical activity, it is easy to chemically react in high temperature and humid environment, resulting in quality deterioration. And it should be kept away from fire and heat sources, because the substance is at risk of exposure to open flames, hot topics or combustion explosions.
Second, the storage container must be tightly sealed. 2% 2C5-difluorobenzoyl chloride is sensitive to water vapor, and contact with water can react violently to form harmful products. Therefore, glass bottles or metal drums lined with special anti-corrosion materials are commonly used for storage to prevent leakage and deterioration.
Third, during transportation, ensure that the container is stable and will not collide or pour. Because it is a dangerous chemical, once it leaks, it not only pollutes the environment, but also poses a threat to human health. Transportation vehicles also need to be equipped with corresponding emergency treatment equipment and protective equipment to deal with emergencies.
Fourth, storage and transportation should be strictly operated in accordance with regulations. Relevant personnel need to be professionally trained and familiar with the characteristics, hazards and emergency disposal methods of 2% 2C5-difluorobenzoyl chloride. At the same time, obvious warning signs should be set up in storage and transportation sites to indicate its danger. In conclusion, the storage and transportation of 2% 2C5-difluorobenzoyl chloride must be done with caution and strict safety regulations, so as to effectively avoid accidents and ensure the safety of personnel and the environment.
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