Linshang Chemical
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2,5-Dichlorobromobenzene
Linshang Chemical
|
HS Code |
650558 |
| Chemical Formula | C6H3BrCl2 |
| Molar Mass | 225.899 g/mol |
| Appearance | Colorless to light - yellow liquid |
| Density | 1.719 g/cm³ |
| Boiling Point | 220 - 222 °C |
| Melting Point | 10 - 12 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 96 °C |
| Vapor Pressure | Low vapor pressure at room temperature |
| Odor | Characteristic aromatic odor |
As an accredited 2,5-Dichlorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2,5 - dichlorobromobenzene packaged in a sealed glass bottle. |
| Storage | 2,5 - dichlorobromobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances like strong oxidizers. Store it in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and maintain its chemical integrity. |
| Shipping | 2,5 - dichlorobromobenzene is shipped in tightly - sealed, corrosion - resistant containers. It is transported under conditions avoiding heat, ignition sources, and incompatible substances to ensure safe delivery. |
Competitive 2,5-Dichlorobromobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,5-Dichlorobromobenzene in China?
As a trusted 2,5-Dichlorobromobenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2,5-Dichlorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2,5-dichlorobromobenzene?
2% 2C5-difluorobenzoic acid, which was not well known in the era of "Tiangong Kaiwu", but now it has a wide range of uses.
In the field of medicinal chemistry, it is an important synthetic raw material. It covers the construction of many drug molecules and needs to be based on it. For example, in the preparation of some antibacterial and anti-inflammatory drugs, 2% 2C5-difluorobenzoic acid can introduce specific functional groups through a series of reactions, giving the drug the desired activity and characteristics to help fight diseases and heal diseases.
In the creation of pesticides, it also plays an important role. Can derive high-efficiency, low-toxicity and environmentally friendly pesticide ingredients. After chemical modification, it can target specific pests or diseases, precisely exert medicinal effects, protect crops and fruits, increase the hope of harvest, and reduce ecological harm.
In the field of materials science, there are also many uses. First, it can be used to synthesize special polymer materials. Polymerize with specific monomers to form polymers with unique properties, such as high heat resistance and chemical corrosion resistance materials, which are very useful in fields such as aerospace and electronics industries that require strict material properties. Second, it can be used as an intermediate in the synthesis of liquid crystal materials to improve the physical properties of liquid crystal materials, such as phase transition temperature, optical anisotropy, etc., for display screen manufacturing to improve display effect and performance.
Furthermore, it is a commonly used reagent in organic synthesis chemistry research. Due to its unique fluorine atom substitution, it affects the reactivity and selectivity, assisting chemists in exploring novel reaction pathways and synthesis strategies, providing more possibilities and ideas for the creation of organic compounds, and promoting the development of organic chemistry.
In the field of medicinal chemistry, it is an important synthetic raw material. It covers the construction of many drug molecules and needs to be based on it. For example, in the preparation of some antibacterial and anti-inflammatory drugs, 2% 2C5-difluorobenzoic acid can introduce specific functional groups through a series of reactions, giving the drug the desired activity and characteristics to help fight diseases and heal diseases.
In the creation of pesticides, it also plays an important role. Can derive high-efficiency, low-toxicity and environmentally friendly pesticide ingredients. After chemical modification, it can target specific pests or diseases, precisely exert medicinal effects, protect crops and fruits, increase the hope of harvest, and reduce ecological harm.
In the field of materials science, there are also many uses. First, it can be used to synthesize special polymer materials. Polymerize with specific monomers to form polymers with unique properties, such as high heat resistance and chemical corrosion resistance materials, which are very useful in fields such as aerospace and electronics industries that require strict material properties. Second, it can be used as an intermediate in the synthesis of liquid crystal materials to improve the physical properties of liquid crystal materials, such as phase transition temperature, optical anisotropy, etc., for display screen manufacturing to improve display effect and performance.
Furthermore, it is a commonly used reagent in organic synthesis chemistry research. Due to its unique fluorine atom substitution, it affects the reactivity and selectivity, assisting chemists in exploring novel reaction pathways and synthesis strategies, providing more possibilities and ideas for the creation of organic compounds, and promoting the development of organic chemistry.
What are the physical properties of 2,5-dichlorobromobenzene?
2% 2C5-difluorobenzoic acid is an organic compound. Its physical properties are as follows:
The appearance is mostly white to light yellow crystalline powder, which is easy to observe and handle. Its melting point is between 155-158 ° C. Within this temperature limit, the substance gradually changes from solid to liquid. This characteristic is quite critical in the separation, purification and identification of substances. The boiling point is about 270 ° C. When the temperature reaches this point, the substance changes sharply from liquid to gaseous state. This boiling point data can be used as an important reference in operations such as distillation.
In terms of solubility, it is slightly soluble in water, which indicates that it interacts weakly with water molecules. However, it can be soluble in some organic solvents, such as ethanol, ether, etc. In these organic solvents, 2% 2C5-difluorobenzoic acid can be uniformly dispersed in molecular state. This solubility characteristic makes it possible to select suitable solvents according to different needs in organic synthesis reactions to ensure the smooth progress of the reaction. In addition, because of its certain stability, it is not easy to chemically react quickly with common substances such as oxygen and carbon dioxide in the air under conventional conditions, so there is no need for extreme harsh conditions during storage and use. However, in specific chemical reaction scenarios, it can demonstrate corresponding chemical activity by virtue of its own structural characteristics and participate in various organic synthesis reactions to prepare more complex and functional organic compounds.
The appearance is mostly white to light yellow crystalline powder, which is easy to observe and handle. Its melting point is between 155-158 ° C. Within this temperature limit, the substance gradually changes from solid to liquid. This characteristic is quite critical in the separation, purification and identification of substances. The boiling point is about 270 ° C. When the temperature reaches this point, the substance changes sharply from liquid to gaseous state. This boiling point data can be used as an important reference in operations such as distillation.
In terms of solubility, it is slightly soluble in water, which indicates that it interacts weakly with water molecules. However, it can be soluble in some organic solvents, such as ethanol, ether, etc. In these organic solvents, 2% 2C5-difluorobenzoic acid can be uniformly dispersed in molecular state. This solubility characteristic makes it possible to select suitable solvents according to different needs in organic synthesis reactions to ensure the smooth progress of the reaction. In addition, because of its certain stability, it is not easy to chemically react quickly with common substances such as oxygen and carbon dioxide in the air under conventional conditions, so there is no need for extreme harsh conditions during storage and use. However, in specific chemical reaction scenarios, it can demonstrate corresponding chemical activity by virtue of its own structural characteristics and participate in various organic synthesis reactions to prepare more complex and functional organic compounds.
What are the chemical properties of 2,5-dichlorobromobenzene?
2% 2C5-difluorobenzoic acid is an organic compound. Its properties are as follows:
This substance is in the state of white to light yellow crystalline powder. The melting point is between 160-163 ° C. This characteristic makes it possible to change from solid to liquid at a specific temperature. In chemical synthesis and other processes, the reaction process and conditions can be controlled according to its melting point.
From the perspective of chemical activity, the carboxyl group in the structure of benzoic acid is acidic and can neutralize with bases. If it encounters sodium hydroxide, the corresponding carboxylate and water are formed. The presence of two fluorine atoms on the benzene ring greatly affects the distribution of molecular electron clouds. Fluorine atoms are highly electronegative and have a strong electron-absorbing effect, which reduces the electron cloud density of the benzene ring, and then enhances the acidity of the carboxyl group. This property is of great significance in organic synthesis and can be used as a unique reaction check point. Through various reactions such as nucleophilic substitution and electrophilic substitution, other functional groups are introduced to prepare various derivatives, which are widely used in medicine, pesticides, materials and many other fields.
In terms of solubility, 2% 2C5-difluorobenzoic acid is slightly soluble in water, but soluble in some organic solvents, such as ethanol and ether. This difference in solubility is crucial in separation, purification and solvent selection. In organic synthesis reactions, selecting a suitable organic solvent can improve the solubility of the reactants, increase the contact probability of the reaction, and make the reaction easier to proceed. In terms of stability, it is usually relatively stable under normal conditions, but under extreme conditions such as high temperature and strong oxidants, reactions such as oxidation and decomposition may occur. Therefore, storage should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, to ensure its chemical stability and avoid deterioration affecting use.
This substance is in the state of white to light yellow crystalline powder. The melting point is between 160-163 ° C. This characteristic makes it possible to change from solid to liquid at a specific temperature. In chemical synthesis and other processes, the reaction process and conditions can be controlled according to its melting point.
From the perspective of chemical activity, the carboxyl group in the structure of benzoic acid is acidic and can neutralize with bases. If it encounters sodium hydroxide, the corresponding carboxylate and water are formed. The presence of two fluorine atoms on the benzene ring greatly affects the distribution of molecular electron clouds. Fluorine atoms are highly electronegative and have a strong electron-absorbing effect, which reduces the electron cloud density of the benzene ring, and then enhances the acidity of the carboxyl group. This property is of great significance in organic synthesis and can be used as a unique reaction check point. Through various reactions such as nucleophilic substitution and electrophilic substitution, other functional groups are introduced to prepare various derivatives, which are widely used in medicine, pesticides, materials and many other fields.
In terms of solubility, 2% 2C5-difluorobenzoic acid is slightly soluble in water, but soluble in some organic solvents, such as ethanol and ether. This difference in solubility is crucial in separation, purification and solvent selection. In organic synthesis reactions, selecting a suitable organic solvent can improve the solubility of the reactants, increase the contact probability of the reaction, and make the reaction easier to proceed. In terms of stability, it is usually relatively stable under normal conditions, but under extreme conditions such as high temperature and strong oxidants, reactions such as oxidation and decomposition may occur. Therefore, storage should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, to ensure its chemical stability and avoid deterioration affecting use.
What is the production method of 2,5-dichlorobromobenzene?
2% 2C5-difluorobenzoic acid is an important intermediate in organic synthesis and has a wide range of uses in the fields of medicine, pesticides, materials, etc. The common methods for its preparation are as follows:
First, the halogenation method using 2,5-dimethylbenzoic acid as raw material. This is the halogenation reaction between 2,5-dimethylbenzoic acid and halogenating reagents, such as chlorine, bromine gas or hydrogen halide, under appropriate reaction conditions. Halogen atoms are introduced at specific positions in the benzene ring, and then the subsequent fluorination reaction is carried out to obtain 2,5-difluorobenzoic acid. The reaction steps are roughly as follows: first place 2,5-dimethylbenzoic acid in a suitable reaction vessel, add an appropriate amount of solvent and catalyst, pass in a halogenated reagent, control the reaction temperature and time, and make the halogenation reaction fully proceed. After the reaction is completed, the halogenated 2,5-dimethylbenzoic acid is obtained through separation, purification and other operations. Then, the halogenated product is reacted with fluorinated reagents, such as potassium fluoride, cesium fluoride, etc., in a specific reaction medium. After heating and stirring, fluorine atoms are replaced by halogen atoms, and finally refined to obtain 2,5-difluorobenzoic acid. The advantage of this method is that the raw materials are relatively easy to obtain and the reaction route is relatively mature; however, the disadvantage is that there are many reaction steps, and halogenated reagents are required, which may cause certain environmental pollution.
Second, the fluorination method using 2,5-dichlorobenzoic acid as the raw material. This is to use 2,5-dichlorobenzoic acid as the starting material, and through the nucleophilic substitution reaction with the fluorination reagent, the chlorine atom is replaced with a fluorine atom to obtain the target product. Usually, a fluorination reagent with higher activity is selected, and suitable catalysts and auxiliaries are added to improve the reaction efficiency and selectivity. For example, in a polar aprotic solvent, 2,5-dichlorobenzoic acid and potassium fluoride can be used as reactants, and an appropriate amount of phase transfer catalyst, such as tetrabutylammonium bromide, can be added, heated and stirred to carry out the reaction. During the reaction process, the reaction temperature, pressure and material ratio should be strictly controlled. After the reaction, 2,5-difluorobenzoic acid is separated by filtration, washing, distillation and other operations. The advantage of this method is that there are relatively few reaction steps and the product purity is high; however, attention should be paid to the corrosiveness and toxicity of fluorinated reagents, and the reaction equipment requirements are high.
Third, the method of constructing the structure of the difluorobenzene ring through multi-step reaction with benzoic acid derivatives as raw materials. This method is more complicated and requires multiple steps such as substitution, cyclization, and fluorination in sequence according to the specific reaction design. For example, a specific benzoic acid derivative is used as the starting material, and a specific substituent is introduced through a nucleophilic substitution reaction to form an intermediate with a specific structure. Then, the cyclization reaction is used to construct the benzene ring structure, and then the fluorine atom is introduced at the 2,5 position of the benzene ring through a selective fluorination reaction. Although this method can flexibly design the reaction route and prepare the 2,5-difluorobenzoic acid derivative with a special structure, the reaction steps are cumbersome, the reaction conditions and operation techniques are extremely demanding, and the yield is often low.
First, the halogenation method using 2,5-dimethylbenzoic acid as raw material. This is the halogenation reaction between 2,5-dimethylbenzoic acid and halogenating reagents, such as chlorine, bromine gas or hydrogen halide, under appropriate reaction conditions. Halogen atoms are introduced at specific positions in the benzene ring, and then the subsequent fluorination reaction is carried out to obtain 2,5-difluorobenzoic acid. The reaction steps are roughly as follows: first place 2,5-dimethylbenzoic acid in a suitable reaction vessel, add an appropriate amount of solvent and catalyst, pass in a halogenated reagent, control the reaction temperature and time, and make the halogenation reaction fully proceed. After the reaction is completed, the halogenated 2,5-dimethylbenzoic acid is obtained through separation, purification and other operations. Then, the halogenated product is reacted with fluorinated reagents, such as potassium fluoride, cesium fluoride, etc., in a specific reaction medium. After heating and stirring, fluorine atoms are replaced by halogen atoms, and finally refined to obtain 2,5-difluorobenzoic acid. The advantage of this method is that the raw materials are relatively easy to obtain and the reaction route is relatively mature; however, the disadvantage is that there are many reaction steps, and halogenated reagents are required, which may cause certain environmental pollution.
Second, the fluorination method using 2,5-dichlorobenzoic acid as the raw material. This is to use 2,5-dichlorobenzoic acid as the starting material, and through the nucleophilic substitution reaction with the fluorination reagent, the chlorine atom is replaced with a fluorine atom to obtain the target product. Usually, a fluorination reagent with higher activity is selected, and suitable catalysts and auxiliaries are added to improve the reaction efficiency and selectivity. For example, in a polar aprotic solvent, 2,5-dichlorobenzoic acid and potassium fluoride can be used as reactants, and an appropriate amount of phase transfer catalyst, such as tetrabutylammonium bromide, can be added, heated and stirred to carry out the reaction. During the reaction process, the reaction temperature, pressure and material ratio should be strictly controlled. After the reaction, 2,5-difluorobenzoic acid is separated by filtration, washing, distillation and other operations. The advantage of this method is that there are relatively few reaction steps and the product purity is high; however, attention should be paid to the corrosiveness and toxicity of fluorinated reagents, and the reaction equipment requirements are high.
Third, the method of constructing the structure of the difluorobenzene ring through multi-step reaction with benzoic acid derivatives as raw materials. This method is more complicated and requires multiple steps such as substitution, cyclization, and fluorination in sequence according to the specific reaction design. For example, a specific benzoic acid derivative is used as the starting material, and a specific substituent is introduced through a nucleophilic substitution reaction to form an intermediate with a specific structure. Then, the cyclization reaction is used to construct the benzene ring structure, and then the fluorine atom is introduced at the 2,5 position of the benzene ring through a selective fluorination reaction. Although this method can flexibly design the reaction route and prepare the 2,5-difluorobenzoic acid derivative with a special structure, the reaction steps are cumbersome, the reaction conditions and operation techniques are extremely demanding, and the yield is often low.
What are the precautions for storing and transporting 2,5-dichlorobromobenzene?
2% 2C5-difluorobenzoic acid is an organic compound. When storing and transporting, many key matters need to be paid attention to. The details are as follows:
Storage
1. ** Dry environment **: This compound has certain hygroscopicity, so it should be stored in a dry place. If the environment is humid, it is easy to cause its moisture absorption and deterioration, which affects the quality and performance. If it is in the warehouse, the relative humidity must be kept within a specific range and moisture should not be invaded.
2. ** Temperature suitable **: 2% 2C5-difluorobenzoic acid is quite sensitive to temperature. High temperature is easy to cause decomposition or accelerate chemical reactions. Low temperature may cause it to solidify, which affects the use. It is usually advisable to store in a cool place with a temperature of 5 ° C - 25 ° C.
3. ** Isolated storage **: Do not mix with oxidants, alkalis and other substances. Because of its acidic nature, it will neutralize with alkalis; mix with oxidants, or cause violent chemical reactions, and even risk explosion. If it should be stored separately from sodium hydroxide, hydrogen peroxide, etc.
4. ** Packaging in good condition **: Before storage, be sure that the packaging is intact. If the packaging is damaged, it will not only cause product leakage and pollute the environment, but also make it contact with air, moisture, etc., accelerating deterioration.
Transportation regulations
1. ** Stable packaging **: Bumps and vibrations during transportation are inevitable, so stable packaging materials are required. For example, it is packed in strong plastic drums or iron drums lined with plastic bags, and fixed with fillers to prevent collision damage.
2. ** Follow regulations **: The transportation of such chemicals must be in strict accordance with relevant national and local regulations. The transporter must have professional qualifications, the transportation vehicle must meet safety standards, and the corresponding transportation license is required.
3. ** Prevent leakage **: Before transportation, carefully check the sealing of the package. During transportation, pay close attention to whether there are any signs of leakage. In the event of a leak, take emergency measures immediately, such as evacuating the crowd, sealing the scene, and collecting the leak with suitable materials.
4. ** Avoid mixed transportation **: As required by storage, it should not be mixed with contraindicated substances during transportation. If it cannot be transported with strong oxidants and strong alkalis, it will prevent reactions caused by vibration and temperature changes during transportation.
Storage
1. ** Dry environment **: This compound has certain hygroscopicity, so it should be stored in a dry place. If the environment is humid, it is easy to cause its moisture absorption and deterioration, which affects the quality and performance. If it is in the warehouse, the relative humidity must be kept within a specific range and moisture should not be invaded.
2. ** Temperature suitable **: 2% 2C5-difluorobenzoic acid is quite sensitive to temperature. High temperature is easy to cause decomposition or accelerate chemical reactions. Low temperature may cause it to solidify, which affects the use. It is usually advisable to store in a cool place with a temperature of 5 ° C - 25 ° C.
3. ** Isolated storage **: Do not mix with oxidants, alkalis and other substances. Because of its acidic nature, it will neutralize with alkalis; mix with oxidants, or cause violent chemical reactions, and even risk explosion. If it should be stored separately from sodium hydroxide, hydrogen peroxide, etc.
4. ** Packaging in good condition **: Before storage, be sure that the packaging is intact. If the packaging is damaged, it will not only cause product leakage and pollute the environment, but also make it contact with air, moisture, etc., accelerating deterioration.
Transportation regulations
1. ** Stable packaging **: Bumps and vibrations during transportation are inevitable, so stable packaging materials are required. For example, it is packed in strong plastic drums or iron drums lined with plastic bags, and fixed with fillers to prevent collision damage.
2. ** Follow regulations **: The transportation of such chemicals must be in strict accordance with relevant national and local regulations. The transporter must have professional qualifications, the transportation vehicle must meet safety standards, and the corresponding transportation license is required.
3. ** Prevent leakage **: Before transportation, carefully check the sealing of the package. During transportation, pay close attention to whether there are any signs of leakage. In the event of a leak, take emergency measures immediately, such as evacuating the crowd, sealing the scene, and collecting the leak with suitable materials.
4. ** Avoid mixed transportation **: As required by storage, it should not be mixed with contraindicated substances during transportation. If it cannot be transported with strong oxidants and strong alkalis, it will prevent reactions caused by vibration and temperature changes during transportation.
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