2,6-Dichlorobenzenesulphonyl Chloride
Linshang Chemical
HS Code |
930707 |
Chemical Formula | C6H3Cl3O2S |
Molar Mass | 245.51 g/mol |
Appearance | White to off - white solid |
Melting Point | 75 - 78 °C |
Boiling Point | Decomposes before boiling |
Solubility In Water | Reacts with water |
Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, chloroform |
Density | Approx. 1.66 g/cm³ |
Vapor Pressure | Low at room temperature |
Odor | Pungent odor |
Hazard Class | Corrosive |
As an accredited 2,6-Dichlorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 2,6 - dichlorobenzenesulphonyl Chloride packaged in a sealed glass bottle. |
Storage | 2,6 - dichlorobenzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances such as strong oxidizers, bases, and moisture. Store it in tightly - sealed containers made of corrosion - resistant materials to prevent leakage and reaction with the environment. |
Shipping | 2,6 - dichlorobenzenesulphonyl chloride is a hazardous chemical. It should be shipped in accordance with strict regulations, using specialized containers to prevent leakage. Shipments must be clearly labeled and handled by trained personnel. |
Competitive 2,6-Dichlorobenzenesulphonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 2,6-Dichlorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
This is a crucial raw material in organic synthesis. In the field of medicine, it is often used as a starting material to synthesize various drugs through multi-step reactions. For example, in the synthesis of some antibacterial drugs, 2% 2C6-difluorobenzoyl chloride can acylate with specific amine compounds to form key intermediates, and then be modified to obtain the final drug with antibacterial activity.
In the field of pesticides, it also plays an important role. It can react with nucleophiles containing nitrogen and sulfur to prepare efficient pesticides. For example, by combining with specific heterocyclic compounds, pesticides that are highly harmful to pests and environmentally friendly are synthesized, and their unique structures endow pesticides with good biological activity and selectivity.
In the field of materials science, 2% 2C6-difluorobenzoyl chloride can participate in the synthesis of polymers. Polymer materials with special properties, such as some high-performance engineering plastics, are prepared by polymerizing with compounds containing hydroxyl groups, amino groups and other functional groups. Due to the introduction of fluorine atoms, the materials have excellent chemical resistance and low dielectric constant.
In addition, in the dye industry, it is also used. It can be used as an important intermediate for the synthesis of new dyes. By reacting with different aromatic amines, phenols and other compounds, dye molecules with diverse structures can be constructed, which brings unique improvements to the color and fastness of dyes.
In summary, 2% 2C6-difluorobenzoyl chloride has a wide range of key uses in many fields, and is of great significance to promote the development of related industries.
First, 2,6-difluorobenzoic acid is used as the starting material. Place 2,6-difluorobenzoic acid in a clean reactor and slowly add sulfoxide chloride in an appropriate proportion. This sulfoxide chloride is used as a chlorination reagent in the reaction, which can convert the carboxyl group into an acyl chloride group. When reacting, pay attention to the control of temperature, and maintain the reaction temperature in a moderate hot bath at a suitable range, usually 50 to 80 degrees Celsius. At the same time, stirring is applied to fully mix the materials and accelerate the reaction. After the reaction is completed, the unreacted sulfoxide chloride and other impurities are removed by vacuum distillation to obtain pure 2,6-difluorobenzoyl chloride. The principle of the chemical reaction is that the carboxyl group of benzoic acid reacts with the chlorine atom of sulfoxide chloride, resulting in the escape of acid chloride, sulfur dioxide and hydrogen chloride gas.
Second, 2,6-difluorotoluene is used as the starting material. First, 2,6-difluorotoluene is placed in a reaction vessel with an appropriate amount of catalyst, such as specific transition metal salts. An appropriate amount of chlorine gas is introduced, and the reaction is initiated by light or heat. In this reaction, chlorine gas replaces the hydrogen atom on the methyl group of toluene under the action of a catalyst, and gradually chlorinates to form 2,6-difluorobenzyl chloride. Then, with a suitable oxidizing agent, such as potassium permanganate, the chloromethyl group of benzyl chloride is oxidized to a carboxyl group to obtain 2,6-difluorobenzoic acid. As mentioned earlier, it is reacted with sulfoxide chloride to convert to 2,6-difluorobenzoyl chloride. This synthesis path step is slightly complicated, but the raw material 2,6-difluorotoluene is more common and cost-effective. When operating, the use of chlorine should be cautious, because it is very toxic, and the control of reaction conditions is related to the purity and yield of the product.
Looking at its properties, it shows a flowing state under normal conditions, such as clear oil, but its color may be slightly yellowish due to some impurities, just like morning light dyed in thin oil. Smell it, the stench is pungent, making people cover their noses. This smell is like a rancid hybrid, with stimulating power, and can penetrate directly into the heart and lungs.
In terms of its chemical activity, it is extremely lively. In contact with water, it is like encountering an enemy, reacting quickly, like water and fire are incompatible, intense and smoke, and release hydrogen chloride gas at the same time. This hydrogen chloride is also highly irritating. It can form a white mist in the air, just like light smoke. If you touch it, it will hurt, and you must not approach it.
Its boiling point has a fixed number, about a specific temperature. At this time, the liquid turns into a gas, such as a rising state. The melting point also has its value. When the temperature drops to a certain point, it will turn from liquid to solid, like sleeping.
2% 2C6-difluorobenzoyl chloride has a density heavier than water. If it enters water, it will sink to the bottom, such as a stone falling into the abyss. Its solubility also has characteristics. It is soluble in many organic solvents, like a fish in water, and it is immiscible. It can blend with organic solvents without distinction.
Because of its strong corrosiveness, it can be damaged by touching objects, whether it is the softness of the skin or the quality of the clothes. And with high chemical activity, it often reacts violently when encountering improper objects. Therefore, when storing and using, it is necessary to be careful and strictly follow the procedures to ensure safety.
In terms of storage, the first choice of environment. It should be placed in a cool and ventilated warehouse. This is dangerous due to heat, and a cool and ventilated place can reduce its risk. The warehouse temperature should be controlled in a specific range. If it is too high, it may cause a reaction. And it should be kept away from fire and heat sources. Open flames and hot topics can cause 2% 2C6-difluorobenzoyl chloride to react violently and cause explosions and other disasters.
Furthermore, it is corrosive and toxic, and must be stored separately from oxidants, alkalis, and edible chemicals when stored. Contact with oxidants or promote chemical reactions, and alkalis meet with them, and they are prone to violent reactions. Mixed storage with edible chemicals is more likely to cause serious consequences such as accidental ingestion.
In packaging, it should not be ignored. Make sure that the packaging is complete and sealed to prevent leakage. If the packaging is damaged, 2% 2C6-difluorobenzoyl chloride escapes, which not only damages the environment, but also poses a threat to those who come into contact.
As for transportation, the transportation vehicle must have the corresponding qualifications, and the escort personnel also need to undergo professional training, familiar with the characteristics of 2% 2C6-difluorobenzoyl chloride and emergency treatment methods. During transportation, it is necessary to prevent exposure to the sun, rain, and high temperature. Summer transportation should be selected when it is cool in the morning and evening, and avoid the high temperature at noon.
When loading and unloading, the operation must be light, and it is strictly forbidden to drop, bump, or collide. Because of its strong corrosiveness, careless loading and unloading can cause package damage, and corrosive liquids can flow out, which can corrode surrounding objects and injure personnel. After the transportation vehicle is used, it should be thoroughly cleaned and disinfected to remove the remaining 2% 2C6-difluorobenzoyl chloride, so as to avoid contaminating other goods during the next transportation or causing damage to the transportation vehicle itself.
1. Toxicity Hazards
This substance has certain toxicity. If inhaled through the respiratory tract, it will cause strong irritation to the respiratory mucosa, causing symptoms such as cough, asthma, breathing difficulties, etc. If accidentally exposed to the skin, it can cause skin burns, redness, swelling, pain, and even affect the nervous system, liver, kidney and other important organ functions after absorption. Once taken by mistake, it will seriously damage the mouth, throat, gastrointestinal tract and other parts, cause corrosive damage, nausea, vomiting, abdominal pain, diarrhea and other conditions, endangering life and health.
II. Fire and explosion hazard
2% 2C6-difluorobenzoyl chloride is flammable, and it is very easy to burn in case of open flames and hot topics. Its vapor and air can form an explosive mixture. In a certain space, when the concentration reaches the explosion limit, it will cause an explosion in case of a fire source. Moreover, during the combustion process, toxic gases such as hydrogen chloride will be released, which will not only exacerbate the fire, but also cause further harm to the environment and human body.
III. Risk of reactivity
This substance is chemically active and can react chemically with a variety of substances. For example, when it comes into contact with water, it will react violently to produce hydrogen chloride gas, which is corrosive and irritating. Encounters with alkalis, alcohols and other substances may also cause violent reactions, or even lead to loss of control, resulting in dangerous consequences.
Fourth, environmental hazards
If 2% 2C6-difluorobenzoyl chloride enters the environment, it will cause pollution to water bodies, soil and atmosphere. The chlorides and other substances produced by its decomposition may change the pH of soil and water bodies, affect the balance of ecosystems, and pose a threat to the survival and reproduction of animals and plants.

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