2-Amino-4-Chloro-5-Methylbenzenesulfonic Acid
Linshang Chemical
HS Code |
903338 |
Chemical Formula | C7H8ClNO3S |
Molecular Weight | 221.66 |
Appearance | Solid (usually a powder) |
Color | Typically white to off - white |
Solubility In Water | Moderate solubility |
Odor | Odorless or very faint odor |
Melting Point | Specific melting point data would depend on purity, but generally in a certain temperature range |
Pka Value | Characteristic pKa related to the acidic group |
Density | A specific density value based on experimental determination |
Stability | Stable under normal storage conditions |
As an accredited 2-Amino-4-Chloro-5-Methylbenzenesulfonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 25 - kg bag packaging for 2 - amino - 4 - chloro - 5 - methylbenzenesulfonic acid. |
Storage | 2 - amino - 4 - chloro - 5 - methylbenzenesulfonic acid should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, flames, and direct sunlight. Store in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Also, ensure it is separated from incompatible substances like strong oxidizers. |
Shipping | 2 - amino - 4 - chloro - 5 - methylbenzenesulfonic acid is shipped in well - sealed, corrosion - resistant containers. Packaging adheres to chemical transportation regulations to prevent leakage and ensure safe transit during handling and carriage. |
Competitive 2-Amino-4-Chloro-5-Methylbenzenesulfonic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 2-Amino-4-Chloro-5-Methylbenzenesulfonic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicine, 2-amino-4-chloro-5-methylbenzenesulfonic acid also has important applications. The synthesis of some drugs requires this as a raw material. Through a series of chemical reactions, molecular structures with specific pharmacological activities are constructed, which play a key role in the treatment of certain diseases.
In addition, in terms of pesticides, it can be used as a raw material for the synthesis of specific pesticides. The synthesized pesticides have significant control effects on crop diseases and pests, can effectively protect crop growth, improve crop yield and quality, and ensure the smooth progress of agricultural production.
Furthermore, in the field of organic synthetic chemistry research, 2-amino-4-chloro-5-methylbenzenesulfonic acid, as an important organic synthesis intermediate, provides an important foundation for researchers to explore the structure and properties of new organic compounds, and helps organic synthetic chemistry to continue to move forward.
Looking at its appearance, it often takes the form of white to off-white crystalline powder. This state makes it relatively stable during storage and transportation, and it is not easy to change the quality due to the morphology.
In terms of solubility, it is slightly soluble in water. This property determines its reaction and application in aqueous systems. In some chemical processes that need to be carried out in aqueous solution, the degree of solubility will affect the reaction rate, product purity and many other aspects.
In terms of melting point, there is a specific value, and this physical constant can be used to identify the purity of the compound. If the purity is quite high, the melting point will approach the theoretical value; conversely, if there are many impurities, the melting point will be shifted.
In terms of stability, under normal storage conditions, its properties are relatively stable. However, if it encounters specific conditions such as high temperature and strong oxidants, chemical reactions may occur, causing changes in its own structure and properties.
As for the density, it also has a corresponding value. This parameter is crucial when it comes to material measurement, mixing, etc., and is related to the accurate allocation of the proportions of each substance in actual production and experiments.
In terms of odor, there is generally no special and obvious odor, which is a more advantageous point in terms of its operating environment and use scenarios, and will not cause adverse effects on workers and the surrounding environment due to strong odor.
First, it can be started from the corresponding halogenated aromatic hydrocarbons. First, take a suitable halogenated benzene, whose halogen atom and methyl are already in an appropriate position. With a chlorination reagent, under appropriate reaction conditions, chlorine atoms are introduced into the benzene ring at a specific position to reach the state of 4-chloro-5-methylhalogenated benzene. Then, through an aminolysis reaction, the halogen atom is replaced by an amino group to obtain 2-amino-4-chloro-5-methylbenzene. Finally, a sulfonating reagent, such as concentrated sulfuric acid, is used to introduce the benzene ring into the sulfonic acid group at a suitable temperature and reaction time, and the final product is 2-amino-4-chloro-5-methylbenzenesulfonic acid. In this process, the reaction conditions of each step need to be carefully controlled, such as temperature, proportion of reactants, reaction time, etc., all of which are related to the yield and purity of the product.
Second, toluene derivatives are used as starting materials. First, the methyl ortho or para-position of toluene is chlorinated to obtain a chlorine-containing toluene derivative. After nitration, nitro is introduced at a specific position. Subsequently, the nitro group is reduced to an amino group to obtain a toluene derivative containing an amino group and chlorine. Finally, through the sulfonation step, the sulfonic acid group is introduced at a suitable position in the benzene ring, and the target product can also be obtained. In this route, the nitration step needs to pay attention to the regioselectivity of the reaction. When reducing the nitro group, select the appropriate reducing agent and reaction conditions to ensure the smooth formation of the amino group and do not affect other groups.
Third, aniline derivatives can be considered as starting materials. The amino group of the aniline is first protected to prevent it from overreacting in the subsequent reaction. After that, chlorination, methylation and other steps, chlorine atoms and methyl groups are introduced into the benzene ring. Finally, the amino protecting group is removed and a sulfonation reaction is carried out to obtain 2-amino-4-chloro-5-methylbenzenesulfonic acid. In this approach, the selection and removal conditions of the protecting group are crucial, not only to ensure the stability of the protecting group in the intermediate reaction step, but also to be able to gently remove it to obtain the target product.
All synthesis methods require detailed investigation of the reaction mechanism and precise control of the reaction conditions, so as to improve the quality and yield of the product and achieve good results in actual preparation.
The first to bear the brunt is the cost of raw materials. If the price of various raw materials required for the synthesis of this acid, such as specific chlorine substitutes, amines and sulfonating reagents, fluctuates due to supply and demand imbalances, changes in origin or changes in production processes, the cost of 2-amino-4-chloro-5-methylbenzenesulfonic acid will change, which in turn will affect the selling price.
Furthermore, the simplicity and advanced degree of the production process are also the key. A delicate and efficient process may reduce energy consumption and yield, so that costs can be controlled and prices can be reduced; however, if the process is crude, energy consumption is high and yield is low, prices are easy to rise.
The state of supply and demand in the market also affects its price. If many industries, such as dyes, pharmaceutical intermediate manufacturing, etc., have a large increase in demand for 2-amino-4-chloro-5-methylbenzenesulfonic acid, and the supply is difficult to respond, the price will rise; conversely, if the supply exceeds the demand, the price will decline.
In addition, regional differences cannot be ignored. Different places have different prices due to differences in transportation costs, tax policies, and market competition. In places with smooth transportation and concentrated chemical industries, the price may be more accessible to the people due to convenient logistics and intense competition; while in remote places, the price may be higher due to inconvenient transportation and reduced competition.
Looking at the previous "Tiangong Kaiwu", although there is no price of this specific compound, its "expensive grain but cheap gold jade" theory also depends on supply and demand and access. The price of 2-amino-4-chloro-5-methylbenzenesulfonic acid today also follows this principle. To sum up, in order to determine the price, it is necessary to monitor market dynamics in real time and consult relevant manufacturers or traders to obtain a near-real price.
In the past, there were many chemical giants in the land of Jiangnan, many of whom were involved in the production of this substance. For example, in the area of Suzhou and Hangzhou, there were factories with exquisite craftsmanship and careful preparation. Its local craftsmen have deeply studied chemical technology, and they strictly control the screening of raw materials and reaction conditions, and strive to produce high-quality products.
Qilu Dadi, there are also famous chemical companies participating in it. With its abundant resources and advanced technology, the manufacturers here have a considerable scale in the production of 2-amino-4-chloro-5-methylbenzenesulfonic acid. From raw material procurement to production processes, there are strict specifications to ensure high product quality.
Furthermore, there are also related manufacturers in Yanzhao Land. The manufacturers there focus on innovation, constantly improve the production process, and improve product quality. Its production of 2-amino-4-chloro-5-methylbenzenesulfonic acid has won many praise in the market.
However, the years pass, and the rise and fall of manufacturers are uncertain. Some manufacturers have either closed down or have been transformed due to market changes or technological innovation. To find a reliable manufacturer at the moment, it is necessary to check the chemical directory in detail, consult industry experts, and conduct on-the-spot inspections in order to obtain accurate information, find high-quality producers, and provide stable raw material support for the required industries.

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