2-Amino-4-Chlorobenzenethiol
Linshang Chemical
HS Code |
575584 |
Chemical Formula | C6H6ClNS |
Molar Mass | 159.64 g/mol |
Appearance | Solid (usually) |
Odor | Typical thiol - like, pungent sulfur - containing odor |
Solubility In Water | Poorly soluble in water |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Hazard Class | May be classified as harmful due to toxicity and flammability potential |
As an accredited 2-Amino-4-Chlorobenzenethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 2 - amino - 4 - chlorobenzenethiol packaged in 100 - gram vials for chemical use. |
Storage | 2 - amino - 4 - chlorobenzenethiol should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly closed container to prevent exposure to air and moisture, which could lead to decomposition or oxidation. Label the storage container clearly to avoid misuse. |
Shipping | 2 - amino - 4 - chlorobenzenethiol is shipped in tightly sealed, corrosion - resistant containers. It's transported under conditions that prevent exposure to heat, moisture, and incompatible substances, ensuring safe delivery. |
Competitive 2-Amino-4-Chlorobenzenethiol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 2-Amino-4-Chlorobenzenethiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Looking at its appearance, at room temperature, 2-amino-4-chlorothiophenol often appears as a white to light yellow crystalline powder. The characteristics of this color and morphology can be an important basis for the identification and preliminary judgment of the substance.
When it comes to melting point, this is a key indicator for measuring the physical properties of a substance. The melting point of 2-amino-4-chlorothiophenol is within a certain range. This value varies slightly due to experimental conditions, but the approximate range can provide a reference for studying its thermal stability and phase transition. The determination of the melting point can help chemists understand the change of the substance during heating, such as the temperature node where the solid state is converted to the liquid state, and then control the temperature conditions in synthesis and purification.
Solubility is also an important physical property. 2-amino-4-chlorothiophenol exhibits a certain solubility in some organic solvents. For example, in common organic solvents such as ethanol and acetone, a certain amount can be dissolved. This solubility characteristic helps to select the appropriate reaction medium in the organic synthesis reaction, so that the reactants can be fully contacted and the reaction can be promoted. In the separation and purification steps, according to the difference in solubility, suitable solvents can be selected for extraction, recrystallization and other operations to obtain high-purity products.
In addition, the substance has a certain odor. Although the odor description is difficult to accurately quantify, its special odor is also part of its physical properties. In actual operation and use, the presence or change of the substance can be preliminarily judged by the odor.
Overall, the physical properties of 2-amino-4-chlorothiophenol, including appearance, melting point, solubility, and odor, are of great significance in chemical research, industrial production, and other fields, providing a foundation for related operations and applications.
In terms of its chemical properties, the amino group (\ (- NH_ {2}\)), chlorine atom (\ (-Cl\)) and mercapto group (\ (-SH\)) in the molecule give it various activities. Amino groups are basic and can react with acids to form corresponding salts. For example, in the case of strong acids, the lone pair of electrons on the amino nitrogen atom can accept protons and form positively charged ammonium ions.
Although the chlorine atom is relatively stable, under certain conditions, such as the presence of strong nucleophiles and under suitable conditions such as temperature and catalyst, nucleophilic substitution reactions can occur. At this time, the nucleophilic reagent will attack the benzene ring carbon atom connected to the chlorine atom and replace the chlorine atom.
Mercapto is highly reactive and easy to be oxidized. In air, it can slowly oxidize to form disulfide bonds (\ (-S - S -\)). And it can complex with a variety of metal ions to form stable metal complexes. In addition, mercapto can also participate in nucleophilic addition reactions and react with compounds containing unsaturated bonds to form new compounds.
2-Amino-4-chlorothiophenol can be used as a synthetic pharmaceutical intermediate in the field of medicinal chemistry due to these chemical properties; in the field of materials science, it can be used to prepare materials with special properties.
In the field of medicinal chemistry, it can be used as a key intermediate for the preparation of a variety of specific drugs. The amino group and chlorine atoms in the Gain molecule endow it with unique reactivity and can undergo delicate chemical reactions with many compounds. By means of organic synthesis, complex molecular structures with specific biological activities can be constructed, such as some innovative drugs used to fight specific diseases.
In the field of materials science, 2-amino-4-chlorothiophenol also plays an important role. Due to the strong affinity of thiophenol groups to metal surfaces, it is often used to modify the surfaces of metal nanomaterials. After modification, metal nanomaterials can often be significantly optimized and improved in terms of optical, electrical and catalytic properties. For example, in catalytic reactions, metal nanocatalysts modified by it can exhibit higher catalytic activity and selectivity, which strongly promotes the efficient progress of specific chemical reactions.
Furthermore, in the dye industry, 2-amino-4-chlorothiophenol can be used as an important raw material for the synthesis of characteristic dyes. Its special molecular structure can introduce specific chromophore groups, so that the synthetic dyes show a unique color and good dyeing properties, which can be widely used in the dyeing process of fabrics, leather and other materials, giving these materials a rich and colorful color performance.
In summary, 2-amino-4-chlorothiophenol has indispensable and important uses in many key fields such as medicine, materials and dyes due to its unique chemical structure and reactivity, and plays a key role in promoting the development and progress of related industries.
In ancient chemical synthesis, the target product is often obtained by multi-step transformation of natural materials. To synthesize 2-amino-4-chlorothiophenol, it can be inferred that it starts from natural substances containing benzene rings. For example, natural benzene-containing aromatics are introduced by halogenation. First select a suitable aromatic hydrocarbon, use chlorine gas or chlorine-containing reagents, and under the action of light or catalyst, make chlorine atoms replace hydrogen atoms at specific positions in the benzene ring to obtain chlorine-containing aromatics.
Then try to introduce amino groups. The idea of converting nitrogen-containing materials can be learned from the ancient method. If ammonia or its derivatives are reacted with chlorinated aromatics, under suitable conditions, the amino group can replace the hydrogen atom at another position on the benzene ring. This step may require specific media and catalytic conditions to promote the reaction.
Finally, the mercaptan group is introduced. Although there is no modern precise organic sulfur synthesis reagent in ancient times, it may be extracted or converted from natural sulfur-containing substances. For example, sulfur-containing ores or plants are treated and converted into active sulfur reagents, which react with benzene ring compounds that already contain amino groups and chlorine, so that the mercaptan group is connected to the benzene ring to obtain 2-amino-4-chlorothiophenol. Although this is the synthesis path based on the thought of "Tiangong Kaiwu", which is different from modern precise synthesis, the concept of material selection and reaction transformation may be the origin of the synthesis idea.
First talk about storage. This compound should be stored in a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, high temperature and humid environment are easy to cause it to deteriorate. Be sure to keep away from fires and heat sources, because organic compounds are flammable, in case of open flames, hot topics or the risk of combustion. The storage area should also be equipped with suitable materials for containing leaks to prevent timely and proper handling in case of accidental leakage. And it should be stored separately from oxidants, acids, etc., to avoid mixed storage, because it may react violently with these substances and endanger safety.
As for transportation, it is necessary to ensure that the packaging is complete and sealed. During transportation, it should be shockproof, anti-collision, and anti-drop to prevent compound leakage due to package damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During driving, it should be protected from exposure to the sun, rain, and high temperature. It is best to transport in the morning and evening in summer to avoid high temperature periods. If transported by road, follow the specified route and do not stop in residential areas and densely populated areas.
In short, the storage and transportation of 2-amino-4-chlorothiophenol must be operated in strict accordance with regulations to ensure the safety of personnel and the environment in an all-round way and avoid accidents.

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