Linshang Chemical
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2-Amino-5-Chloronitrobenzene
Linshang Chemical
|
HS Code |
185703 |
| Chemical Formula | C6H5ClN2O2 |
| Molar Mass | 172.57 g/mol |
| Appearance | Yellow - brown crystals |
| Melting Point | 108 - 110 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, acetone |
| Odor | Characteristic odor |
| Hazard Class | Harmful if swallowed, inhaled or in contact with skin |
As an accredited 2-Amino-5-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 25 - kg drum packaging for 2 - amino - 5 - chloronitrobenzene chemical. |
| Storage | 2 - amino - 5 - chloronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure. Store separately from oxidizing agents and incompatible substances to avoid potential reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 2 - amino - 5 - chloronitrobenzene is a hazardous chemical. It should be shipped in accordance with strict regulations, using properly labeled, leak - proof containers, and transported by carriers licensed for hazardous materials. |
Competitive 2-Amino-5-Chloronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Amino-5-Chloronitrobenzene in China?
As a trusted 2-Amino-5-Chloronitrobenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Amino-5-Chloronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-amino-5-chloronitrobenzene?
2-% amino-5-bromopyridine, its main uses are as follows:
First, in the field of pharmaceutical synthesis, this is a key intermediate. It can be integrated into the molecular structure of many drugs through specific chemical reaction steps. For example, when developing some antibacterial drugs, 2-amino-5-bromopyridine can react with other organic compounds by nucleophilic substitution and condensation with its active chemical properties of amino and bromine groups, and then construct complex drug molecular structures with antibacterial activity, providing effective drug options for human resistance to bacterial infections.
Second, it also plays an indispensable role in the creation of pesticides. Through a reasonable design and synthesis path, it can be converted into pesticide ingredients with high insecticidal, bactericidal or herbicidal properties. Due to its special chemical structure, it can interfere with the physiological and metabolic processes of pests and pathogens, and has a relatively small impact on the environment. It is in line with the current trend of green pesticide development, and helps to ensure the yield and quality of crops and reduce the pressure on the environment caused by agricultural production.
Third, in the field of materials science, 2-amino-5-bromopyridine can be used as a starting material for the preparation of functional materials. For example, when synthesizing organic materials with photoelectric properties, they can be used as structural units to participate in the construction of polymers, endowing the materials with unique optical and electrical properties, such as good fluorescence emission properties or semiconductor properties, etc. The development of new optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells shows potential application value and promotes technological innovation and development in the field of materials science.
First, in the field of pharmaceutical synthesis, this is a key intermediate. It can be integrated into the molecular structure of many drugs through specific chemical reaction steps. For example, when developing some antibacterial drugs, 2-amino-5-bromopyridine can react with other organic compounds by nucleophilic substitution and condensation with its active chemical properties of amino and bromine groups, and then construct complex drug molecular structures with antibacterial activity, providing effective drug options for human resistance to bacterial infections.
Second, it also plays an indispensable role in the creation of pesticides. Through a reasonable design and synthesis path, it can be converted into pesticide ingredients with high insecticidal, bactericidal or herbicidal properties. Due to its special chemical structure, it can interfere with the physiological and metabolic processes of pests and pathogens, and has a relatively small impact on the environment. It is in line with the current trend of green pesticide development, and helps to ensure the yield and quality of crops and reduce the pressure on the environment caused by agricultural production.
Third, in the field of materials science, 2-amino-5-bromopyridine can be used as a starting material for the preparation of functional materials. For example, when synthesizing organic materials with photoelectric properties, they can be used as structural units to participate in the construction of polymers, endowing the materials with unique optical and electrical properties, such as good fluorescence emission properties or semiconductor properties, etc. The development of new optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells shows potential application value and promotes technological innovation and development in the field of materials science.
What are the physical properties of 2-amino-5-chloronitrobenzene?
2-% hydroxy-5-mercaptobenzimidazole is a unique organic compound. Its physical properties are quite special, let me tell you in detail.
This compound is mostly solid at room temperature. Looking at its appearance, it is usually a white to light yellow crystalline powder with a fine texture. As for the smell, it usually does not have a strong pungent smell and is relatively mild.
When it comes to solubility, the solubility of 2-% hydroxy-5-mercaptobenzimidazole in water is relatively limited, but it exhibits good solubility in some organic solvents. Organic solvents such as ethanol and acetone can dissolve it, which provides convenience for its use in many chemical experiments and industrial applications.
Its melting point is also one of the important physical properties. After precise determination, its melting point is in a specific temperature range, which is of great significance for identifying and purifying the compound. During the heating process, when the melting point is reached, 2-% hydroxy-5-mercaptobenzimidazole gradually changes from solid state to liquid state, and this phase transition process follows certain physical laws.
In addition, the stability of the compound is also worthy of attention. Under general environmental conditions, 2-% hydroxy-5-mercaptobenzimidazole has certain stability. When it encounters specific chemical substances, high temperature, strong light and other factors, its structure may change, which in turn affects its physical properties and chemical activities.
In summary, the physical properties of 2-% hydroxy-5-mercaptobenzimidazole, such as appearance, odor, solubility, melting point, and stability, are essential for in-depth understanding of the properties of this compound and its applications in chemical, pharmaceutical, and other fields.
This compound is mostly solid at room temperature. Looking at its appearance, it is usually a white to light yellow crystalline powder with a fine texture. As for the smell, it usually does not have a strong pungent smell and is relatively mild.
When it comes to solubility, the solubility of 2-% hydroxy-5-mercaptobenzimidazole in water is relatively limited, but it exhibits good solubility in some organic solvents. Organic solvents such as ethanol and acetone can dissolve it, which provides convenience for its use in many chemical experiments and industrial applications.
Its melting point is also one of the important physical properties. After precise determination, its melting point is in a specific temperature range, which is of great significance for identifying and purifying the compound. During the heating process, when the melting point is reached, 2-% hydroxy-5-mercaptobenzimidazole gradually changes from solid state to liquid state, and this phase transition process follows certain physical laws.
In addition, the stability of the compound is also worthy of attention. Under general environmental conditions, 2-% hydroxy-5-mercaptobenzimidazole has certain stability. When it encounters specific chemical substances, high temperature, strong light and other factors, its structure may change, which in turn affects its physical properties and chemical activities.
In summary, the physical properties of 2-% hydroxy-5-mercaptobenzimidazole, such as appearance, odor, solubility, melting point, and stability, are essential for in-depth understanding of the properties of this compound and its applications in chemical, pharmaceutical, and other fields.
What are the chemical properties of 2-amino-5-chloronitrobenzene?
2-% amino-5-bromopyridine is an organic compound with multiple unique chemical properties and an important position in the field of organic synthesis.
It is in the form of white to light yellow crystalline powder and is stable at room temperature. However, when it encounters strong oxidants, strong acids, and strong bases, it is easy to chemically react and change its structure or properties. This is because the amino group is alkaline and can form salts with acids; the bromine atom has a certain nucleophilic substitution activity.
The amino group of 2-% amino-5-bromopyridine can participate in many reactions. For example, it reacts with acyl chloride and acid anhydride to form amide compounds, which is an important path for the construction of organic molecules containing amide bonds. Amide bonds are widely found in drugs, natural products and materials. Schiff base is widely used in coordination chemistry and catalysis.
Its bromine atom also has high reactivity. Under appropriate conditions, nucleophilic substitution can occur, which is replaced by hydroxyl, amino, alkoxy and other nucleophilic reagents. If it reacts with alcohols under basic conditions, bromine atoms can be replaced by alkoxy groups to generate corresponding ether compounds. And it can participate in metal-catalyzed coupling reactions, such as Suzuki coupling reaction with borate esters catalyzed by palladium, to construct carbon-carbon bonds, realize the diversified modification of the structure of pyridine derivatives, and lay the foundation for the creation of new drugs and functional materials.
From the physical properties, 2-% amino-5-bromopyridine is slightly soluble in water, but it is more soluble in common organic solvents such as dichloromethane, chloroform, ethanol, ether, etc. This solubility is conducive to the separation and purification of it as a reactant or product in organic synthesis reactions.
It is in the form of white to light yellow crystalline powder and is stable at room temperature. However, when it encounters strong oxidants, strong acids, and strong bases, it is easy to chemically react and change its structure or properties. This is because the amino group is alkaline and can form salts with acids; the bromine atom has a certain nucleophilic substitution activity.
The amino group of 2-% amino-5-bromopyridine can participate in many reactions. For example, it reacts with acyl chloride and acid anhydride to form amide compounds, which is an important path for the construction of organic molecules containing amide bonds. Amide bonds are widely found in drugs, natural products and materials. Schiff base is widely used in coordination chemistry and catalysis.
Its bromine atom also has high reactivity. Under appropriate conditions, nucleophilic substitution can occur, which is replaced by hydroxyl, amino, alkoxy and other nucleophilic reagents. If it reacts with alcohols under basic conditions, bromine atoms can be replaced by alkoxy groups to generate corresponding ether compounds. And it can participate in metal-catalyzed coupling reactions, such as Suzuki coupling reaction with borate esters catalyzed by palladium, to construct carbon-carbon bonds, realize the diversified modification of the structure of pyridine derivatives, and lay the foundation for the creation of new drugs and functional materials.
From the physical properties, 2-% amino-5-bromopyridine is slightly soluble in water, but it is more soluble in common organic solvents such as dichloromethane, chloroform, ethanol, ether, etc. This solubility is conducive to the separation and purification of it as a reactant or product in organic synthesis reactions.
What are the synthesis methods of 2-amino-5-chloronitrobenzene?
The synthesis method of 2-% hydroxy-5-bromopyridyl naphthalene has been known for a long time. There are many methods, each has its advantages and disadvantages, and needs to be selected according to the actual situation.
First, with naphthalene as the group, the hydroxyl group is first introduced, and then the bromopyridyl group is added. The halogenation reaction can be used to add bromine to the specific position of the naphthalene with a suitable halogenating agent, and then the nucleophilic substitution is used to access the pyridyl group, and then the hydroxylation reaction is used to introduce the hydroxyl group. This process requires precise temperature control and the selection of a suitable catalyst to improve the reaction efficiency and reduce side reactions.
Second, pyridine is used as the starting point. Bromine is introduced at the 5-position The naphthalene group can be attached to pyridine by Fourier-gram reaction, and then hydroxylated to obtain the target product. This approach requires attention to the reaction conditions to prevent damage to the pyridine ring.
Third, palladium-catalyzed coupling reaction is used. Brominated pyridine derivatives and hydroxyl naphthalene derivatives are used as materials, and the power of palladium catalyst is used to couple the two. This method has high selectivity and mild reaction conditions, but the palladium catalyst is expensive and costly. During operation, the reaction system has strict requirements for anhydrous and oxygen-free.
And other heterocyclic compounds are used as starting materials, and the structure of 2-hydroxy-5-brominopyridine naphthalene is gradually constructed through multi-step reaction. Although this kind of method is complicated, it can obtain special structural products, which are suitable for specific needs.
Synthesis of this compound, the selection of raw materials and the control of reaction conditions are all crucial. It is necessary to comprehensively consider factors such as cost, yield, product purity, etc. After repeated tests, the best synthesis path is found to achieve the ideal synthesis effect.
First, with naphthalene as the group, the hydroxyl group is first introduced, and then the bromopyridyl group is added. The halogenation reaction can be used to add bromine to the specific position of the naphthalene with a suitable halogenating agent, and then the nucleophilic substitution is used to access the pyridyl group, and then the hydroxylation reaction is used to introduce the hydroxyl group. This process requires precise temperature control and the selection of a suitable catalyst to improve the reaction efficiency and reduce side reactions.
Second, pyridine is used as the starting point. Bromine is introduced at the 5-position The naphthalene group can be attached to pyridine by Fourier-gram reaction, and then hydroxylated to obtain the target product. This approach requires attention to the reaction conditions to prevent damage to the pyridine ring.
Third, palladium-catalyzed coupling reaction is used. Brominated pyridine derivatives and hydroxyl naphthalene derivatives are used as materials, and the power of palladium catalyst is used to couple the two. This method has high selectivity and mild reaction conditions, but the palladium catalyst is expensive and costly. During operation, the reaction system has strict requirements for anhydrous and oxygen-free.
And other heterocyclic compounds are used as starting materials, and the structure of 2-hydroxy-5-brominopyridine naphthalene is gradually constructed through multi-step reaction. Although this kind of method is complicated, it can obtain special structural products, which are suitable for specific needs.
Synthesis of this compound, the selection of raw materials and the control of reaction conditions are all crucial. It is necessary to comprehensively consider factors such as cost, yield, product purity, etc. After repeated tests, the best synthesis path is found to achieve the ideal synthesis effect.
What are the precautions for storing and transporting 2-amino-5-chloronitrobenzene?
When storing and transporting 2-% amino-5-bromopyridone, pay attention to many things.
Its properties are chemical substances, and when storing, the first environmental conditions. It must be placed in a cool, dry and well-ventilated place. Because if the substance is exposed to high temperature or humidity, it may cause deterioration. High temperature can cause its chemical structure to change, and humidity may cause it to absorb moisture, affecting purity. For example, if stored in a hot and humid place, it is still placed in a steamer, and its quality will gradually deteriorate.
Furthermore, the storage place should be kept away from fire and heat sources. Because it may be flammable or react violently in contact with fire or heat. Just like dry wood meets fire, the consequences are unimaginable. And it needs to be stored separately from oxidants, acids, alkalis, etc., and cannot be mixed. These types of substances come into contact with them, or react chemically, endangering safety.
When transporting, it should not be underestimated. The packaging must be tight and firm to ensure that no leakage occurs during transportation. If the packaging is omitted, the substance leaks out, or damages the environment, or endangers the safety of transporters. And the transportation process needs to follow relevant regulations and standards, and the transportation vehicle should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. In the event of an accident, it can be responded to in time.
The escort personnel must be familiar with the characteristics of the substance and emergency treatment methods. In case of leakage, do not panic, and take effective measures quickly according to the established procedures to avoid the expansion of harm. Transportation route planning should also be careful to avoid densely populated areas and environmentally sensitive areas to prevent serious losses in the event of an accident. In this way, the storage and transportation of 2-amino-5-bromopyridone should be ensured safely.
Its properties are chemical substances, and when storing, the first environmental conditions. It must be placed in a cool, dry and well-ventilated place. Because if the substance is exposed to high temperature or humidity, it may cause deterioration. High temperature can cause its chemical structure to change, and humidity may cause it to absorb moisture, affecting purity. For example, if stored in a hot and humid place, it is still placed in a steamer, and its quality will gradually deteriorate.
Furthermore, the storage place should be kept away from fire and heat sources. Because it may be flammable or react violently in contact with fire or heat. Just like dry wood meets fire, the consequences are unimaginable. And it needs to be stored separately from oxidants, acids, alkalis, etc., and cannot be mixed. These types of substances come into contact with them, or react chemically, endangering safety.
When transporting, it should not be underestimated. The packaging must be tight and firm to ensure that no leakage occurs during transportation. If the packaging is omitted, the substance leaks out, or damages the environment, or endangers the safety of transporters. And the transportation process needs to follow relevant regulations and standards, and the transportation vehicle should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. In the event of an accident, it can be responded to in time.
The escort personnel must be familiar with the characteristics of the substance and emergency treatment methods. In case of leakage, do not panic, and take effective measures quickly according to the established procedures to avoid the expansion of harm. Transportation route planning should also be careful to avoid densely populated areas and environmentally sensitive areas to prevent serious losses in the event of an accident. In this way, the storage and transportation of 2-amino-5-bromopyridone should be ensured safely.
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