Linshang Chemical
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2-Bromo-1,3-Dichlorobenzene
Linshang Chemical
|
HS Code |
756244 |
| Chemical Formula | C6H3BrCl2 |
| Molar Mass | 225.898 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 229 - 231 °C |
| Melting Point | -10 °C |
| Density | 1.729 g/cm³ (at 20 °C) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Flash Point | 104 °C |
| Odor | Pungent |
As an accredited 2-Bromo-1,3-Dichlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2 - bromo - 1,3 - dichlorobenzene packaged in a sealed glass bottle. |
| Storage | 2 - bromo - 1,3 - dichlorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources to prevent fire risks. Keep it in a tightly sealed container to avoid vapor leakage. Store it separately from oxidizing agents and reactive substances to prevent chemical reactions. Label the storage clearly for easy identification and safety management. |
| Shipping | 2 - bromo - 1,3 - dichlorobenzene is shipped in sealed, corrosion - resistant containers. These are carefully packed in sturdy outer boxes with appropriate cushioning to prevent breakage during transit, following strict hazardous chemical shipping regulations. |
Competitive 2-Bromo-1,3-Dichlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Bromo-1,3-Dichlorobenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Bromo-1,3-Dichlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-bromo-1,3-dichlorobenzene?
2-% cyanogen-1,3-dibromobenzene, also known as 2-cyano-1,3-dibromobenzene, has the following main uses:
First, in the field of organic synthesis, it is a very critical intermediate. A series of organic compounds with special structures and properties can be derived through various chemical reactions. For example, in the construction of complex cyclic structure compounds, the cyanyl group and bromine atoms can participate in different reaction pathways. Cyanyl groups can be converted into carboxyl groups by hydrolysis reaction, and then participate in esterification, amidation and other reactions; bromine atoms can introduce various functional groups, such as alkoxy groups and amino groups, through nucleophilic substitution reactions, so as to synthesize rich organic molecules, providing key synthetic building blocks for pharmaceutical chemistry, materials science and other fields.
Second, it shows important value in drug research and development. Due to the special structure of this compound, it can be used as a key structural fragment of the lead compound. Medicinal chemists can use it as a basis to carry out structural modification and optimization work to explore new drug molecules with specific biological activities. For example, by structural modification, it is expected to obtain drugs with high affinity and selectivity for specific disease targets, providing potential drug candidates for the treatment of difficult diseases such as tumors and neurological diseases.
Third, in the field of materials science, it can be used to prepare functional materials with unique optoelectronic properties. For example, by introducing it into the synthesis of polymer materials, the strong polarity of the cyanyl group and the influence of bromine atoms on the distribution of molecular electron clouds can be used to regulate the electrical and optical properties of the materials, and new functional materials suitable for organic light emitting diodes (OLEDs), organic solar cells, etc. can be prepared to improve the performance and efficiency of these devices.
First, in the field of organic synthesis, it is a very critical intermediate. A series of organic compounds with special structures and properties can be derived through various chemical reactions. For example, in the construction of complex cyclic structure compounds, the cyanyl group and bromine atoms can participate in different reaction pathways. Cyanyl groups can be converted into carboxyl groups by hydrolysis reaction, and then participate in esterification, amidation and other reactions; bromine atoms can introduce various functional groups, such as alkoxy groups and amino groups, through nucleophilic substitution reactions, so as to synthesize rich organic molecules, providing key synthetic building blocks for pharmaceutical chemistry, materials science and other fields.
Second, it shows important value in drug research and development. Due to the special structure of this compound, it can be used as a key structural fragment of the lead compound. Medicinal chemists can use it as a basis to carry out structural modification and optimization work to explore new drug molecules with specific biological activities. For example, by structural modification, it is expected to obtain drugs with high affinity and selectivity for specific disease targets, providing potential drug candidates for the treatment of difficult diseases such as tumors and neurological diseases.
Third, in the field of materials science, it can be used to prepare functional materials with unique optoelectronic properties. For example, by introducing it into the synthesis of polymer materials, the strong polarity of the cyanyl group and the influence of bromine atoms on the distribution of molecular electron clouds can be used to regulate the electrical and optical properties of the materials, and new functional materials suitable for organic light emitting diodes (OLEDs), organic solar cells, etc. can be prepared to improve the performance and efficiency of these devices.
What are the physical properties of 2-bromo-1,3-dichlorobenzene?
2-% chloro-1,3-dibromobenzene is an organic compound. Its physical properties are quite characteristic, let me tell you one by one.
Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid, with clear texture. This color characteristic can be directly observed in ordinary environments.
Smell its smell, often with a special aromatic smell, but this aroma is not pleasant fragrance, inhaling too much may have adverse effects on the human body, so it needs to be treated with caution.
Talking about the melting point, it is about -7 ° C. This value means that when the ambient temperature drops to about -7 ° C, the substance will gradually change from liquid to solid state. If you want to maintain its liquid state, you need to make the ambient temperature higher than this value.
In terms of boiling point, it is roughly in the range of 208-210 ° C. When the temperature rises to the boiling point, 2-% chlorine-1,3-dibromobenzene will quickly vaporize and convert from liquid to gaseous state.
When it comes to density, it is about 2.018g/cm ³, which is higher than the density of water. Therefore, when placed in water, it will sink to the bottom.
In terms of solubility, 2-% chlorine-1,3-dibromobenzene is insoluble in water, but soluble in most organic solvents, such as ethanol, ether, benzene, etc. This property is due to the difference in its molecular structure and the forces between water molecules and organic solvent molecules. In organic solvents, their molecules can form relatively stable interactions with solvent molecules, making them easy to dissolve.
Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid, with clear texture. This color characteristic can be directly observed in ordinary environments.
Smell its smell, often with a special aromatic smell, but this aroma is not pleasant fragrance, inhaling too much may have adverse effects on the human body, so it needs to be treated with caution.
Talking about the melting point, it is about -7 ° C. This value means that when the ambient temperature drops to about -7 ° C, the substance will gradually change from liquid to solid state. If you want to maintain its liquid state, you need to make the ambient temperature higher than this value.
In terms of boiling point, it is roughly in the range of 208-210 ° C. When the temperature rises to the boiling point, 2-% chlorine-1,3-dibromobenzene will quickly vaporize and convert from liquid to gaseous state.
When it comes to density, it is about 2.018g/cm ³, which is higher than the density of water. Therefore, when placed in water, it will sink to the bottom.
In terms of solubility, 2-% chlorine-1,3-dibromobenzene is insoluble in water, but soluble in most organic solvents, such as ethanol, ether, benzene, etc. This property is due to the difference in its molecular structure and the forces between water molecules and organic solvent molecules. In organic solvents, their molecules can form relatively stable interactions with solvent molecules, making them easy to dissolve.
What are the chemical properties of 2-bromo-1,3-dichlorobenzene?
2-% -1,3-dichlorobenzene, its chemical properties are very special. This substance is yellow to light-colored liquid, has an irritating taste, and is soluble in many kinds of water, but has little solubility in water.
Due to its chemical activity, the presence of a chlorine atom (-OH) makes it possible to reverse the reaction of the alkyl group. The alkyl group is nuclear and easily substituted for the alkyl group. For example, it can be substituted for the alkyl group to form an ether compound of the phase. The alkyl group can also be esterified and reacted, and the alkyl acid can form an ester under the action of catalysis.
Furthermore, the chlorine atom in the molecule, due to its chemical properties, changes the density of benzene, and affects the reactivity of benzene. The chlorine atom is the base group and the base group, so the substituted antigroup is mostly generated in the base group and the base group. If the nitrification is reversed, the nitro group (-NO ²) is oriented to the base group and the base group, and the nitro compound is formed.
In addition, 2-% -1,3-dichlorobenzene may also be oxidized. Under the action of suitable oxidation, the base group can be oxidized by an aldehyde group (-CHO) or a carboxyl group (-COOH), and the chlorine atom may also generate the base group and be replaced by other groups under specific conditions.
Therefore, the existence of 2-% -1,3-dichlorobenzene-based chlorine atoms shows rich chemical properties, which can be used for synthesis and chemical engineering, or for general purposes, and can be used for synthesis.
Due to its chemical activity, the presence of a chlorine atom (-OH) makes it possible to reverse the reaction of the alkyl group. The alkyl group is nuclear and easily substituted for the alkyl group. For example, it can be substituted for the alkyl group to form an ether compound of the phase. The alkyl group can also be esterified and reacted, and the alkyl acid can form an ester under the action of catalysis.
Furthermore, the chlorine atom in the molecule, due to its chemical properties, changes the density of benzene, and affects the reactivity of benzene. The chlorine atom is the base group and the base group, so the substituted antigroup is mostly generated in the base group and the base group. If the nitrification is reversed, the nitro group (-NO ²) is oriented to the base group and the base group, and the nitro compound is formed.
In addition, 2-% -1,3-dichlorobenzene may also be oxidized. Under the action of suitable oxidation, the base group can be oxidized by an aldehyde group (-CHO) or a carboxyl group (-COOH), and the chlorine atom may also generate the base group and be replaced by other groups under specific conditions.
Therefore, the existence of 2-% -1,3-dichlorobenzene-based chlorine atoms shows rich chemical properties, which can be used for synthesis and chemical engineering, or for general purposes, and can be used for synthesis.
What are the preparation methods of 2-bromo-1,3-dichlorobenzene?
The preparation method of 2-% pentyl-1,3-dibromobenzene is a very important topic in the field of organic chemical synthesis. The common methods for its preparation are as follows:
First, benzene is used as the starting material, and the pentyl group is introduced through the pentylation reaction. In this step, pentyl halide and benzene can be selected. Under the catalysis of Lewis acid such as aluminum trichloride, the Fu-gram alkylation reaction occurs. Subsequently, under suitable reaction conditions, the resulting pentyl benzene is brominated. Usually, liquid bromine can be used, and under the action of catalysts such as iron powder or iron tribromide, the bromine atom can selectively replace the hydrogen atom on the benzene ring in the ortho or para-position with the pentyl group. After separation and purification, 2-% pentyl-1,3-dibromobenzene can be obtained.
Second, benzene can also be brominated first to obtain 1,3-dibromobenzene. After that, the pentyl group is introduced through the Fu-gram alkylation reaction. In this process, suitable catalysts are also required, and attention should be paid to the control of reaction conditions to improve the yield and purity of the target product.
Third, if the aromatic compound containing pentyl group is used as the starting material, and the substituent localization effect on the benzene ring is conducive to the substitution of bromine atoms at a specific position, the bromination reaction can be directly carried out. For example, some pentylbenzene derivatives with guide groups can preferentially replace bromine atoms to the target position under appropriate bromination reagents and reaction conditions, and then obtain 2-% pentyl-1,3-dibromobenzene.
In the process of preparing 2-% pentyl-1,3-dibromobenzene, all steps need to be carefully handled. From the selection of raw materials, the amount of catalyst, the control of reaction temperature and time, to the separation and purification of the product, the quality and yield of the final product are all related. It is necessary to carefully optimize the synthesis route according to the specific experimental conditions and requirements in order to achieve the purpose of efficient preparation.
First, benzene is used as the starting material, and the pentyl group is introduced through the pentylation reaction. In this step, pentyl halide and benzene can be selected. Under the catalysis of Lewis acid such as aluminum trichloride, the Fu-gram alkylation reaction occurs. Subsequently, under suitable reaction conditions, the resulting pentyl benzene is brominated. Usually, liquid bromine can be used, and under the action of catalysts such as iron powder or iron tribromide, the bromine atom can selectively replace the hydrogen atom on the benzene ring in the ortho or para-position with the pentyl group. After separation and purification, 2-% pentyl-1,3-dibromobenzene can be obtained.
Second, benzene can also be brominated first to obtain 1,3-dibromobenzene. After that, the pentyl group is introduced through the Fu-gram alkylation reaction. In this process, suitable catalysts are also required, and attention should be paid to the control of reaction conditions to improve the yield and purity of the target product.
Third, if the aromatic compound containing pentyl group is used as the starting material, and the substituent localization effect on the benzene ring is conducive to the substitution of bromine atoms at a specific position, the bromination reaction can be directly carried out. For example, some pentylbenzene derivatives with guide groups can preferentially replace bromine atoms to the target position under appropriate bromination reagents and reaction conditions, and then obtain 2-% pentyl-1,3-dibromobenzene.
In the process of preparing 2-% pentyl-1,3-dibromobenzene, all steps need to be carefully handled. From the selection of raw materials, the amount of catalyst, the control of reaction temperature and time, to the separation and purification of the product, the quality and yield of the final product are all related. It is necessary to carefully optimize the synthesis route according to the specific experimental conditions and requirements in order to achieve the purpose of efficient preparation.
What are the precautions for the use of 2-bromo-1,3-dichlorobenzene?
2-% -1,3-dichlorobenzene is an important chemical substance. During use, it is important to pay attention to the problem.
First, safety and prevention are of paramount importance. This compound is toxic to a certain extent, and it can be a great success for people's health. Users should wear appropriate anti-pollution devices, such as gas masks, to prevent respiratory inhalation; they should also wear anti-inhalation gloves and eyewear to avoid skin contact and eye contamination. If it is accidentally connected, it should be washed with a large amount of water immediately. If it is heavy, it needs to be treated quickly.
Second, the storage should not be ignored. It should be stored in a well-ventilated and well-ventilated environment, which can cause ignition and explosion. Because of its flammability, in case of open fire and high temperature, it may cause ignition and explosion. And it should be stored in equal parts of oxidation and acid to prevent biochemical reactions.
Third, the operation of the use must be followed. The grid should be operated according to the method and quantity shown in the photo and the description. It is not allowed to change the use method or use it in excess without authorization, so as to avoid shadow effect, and even cause safety accidents. The operation environment needs to be well maintained, so as to reduce its severity in the air, and the harm of less people.
Fourth, the environment protection should also be followed. During the use process, avoid leakage into the environment. If there is any leakage, immediately take urgent measures, such as absorbing with inert materials such as sand and vermiculite, and properly collect it to prevent pollution caused by soil, water sources, etc.
Therefore, the use of 2-%-1,3-dichlorobenzene is safe, reliable, and reliable, so as to ensure its effectiveness and protect people's safety and environment from harm.
First, safety and prevention are of paramount importance. This compound is toxic to a certain extent, and it can be a great success for people's health. Users should wear appropriate anti-pollution devices, such as gas masks, to prevent respiratory inhalation; they should also wear anti-inhalation gloves and eyewear to avoid skin contact and eye contamination. If it is accidentally connected, it should be washed with a large amount of water immediately. If it is heavy, it needs to be treated quickly.
Second, the storage should not be ignored. It should be stored in a well-ventilated and well-ventilated environment, which can cause ignition and explosion. Because of its flammability, in case of open fire and high temperature, it may cause ignition and explosion. And it should be stored in equal parts of oxidation and acid to prevent biochemical reactions.
Third, the operation of the use must be followed. The grid should be operated according to the method and quantity shown in the photo and the description. It is not allowed to change the use method or use it in excess without authorization, so as to avoid shadow effect, and even cause safety accidents. The operation environment needs to be well maintained, so as to reduce its severity in the air, and the harm of less people.
Fourth, the environment protection should also be followed. During the use process, avoid leakage into the environment. If there is any leakage, immediately take urgent measures, such as absorbing with inert materials such as sand and vermiculite, and properly collect it to prevent pollution caused by soil, water sources, etc.
Therefore, the use of 2-%-1,3-dichlorobenzene is safe, reliable, and reliable, so as to ensure its effectiveness and protect people's safety and environment from harm.
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