Linshang Chemical
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2-Bromo-1,4-Dichlorobenzene
Linshang Chemical
|
HS Code |
752366 |
| Chemical Formula | C6H3BrCl2 |
| Molar Mass | 225.90 g/mol |
| Appearance | White to off - white solid |
| Boiling Point | 242 - 244 °C |
| Melting Point | 42 - 44 °C |
| Density | 1.78 g/cm³ (estimated) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Odor | Characteristic aromatic odor |
| Flash Point | 109.6 °C |
As an accredited 2-Bromo-1,4-Dichlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 2 - bromo - 1,4 - dichlorobenzene, well - sealed for chemical storage. |
| Storage | 2 - bromo - 1,4 - dichlorobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat and ignition. Keep it in a tightly sealed container, preferably made of corrosion - resistant material. Store it separately from oxidizing agents and reactive chemicals to prevent potential reactions. Clearly label the storage container for easy identification and safety. |
| Shipping | 2 - bromo - 1,4 - dichlorobenzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous material regulations, ensuring proper labeling and secure packaging to prevent leaks during transit. |
Competitive 2-Bromo-1,4-Dichlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 2-Bromo-1,4-Dichlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-bromo-1,4-dichlorobenzene?
2-% hydroxyl-1,4-dichlorobenzene is an organic compound. Its properties have several characteristics.
In terms of its physical properties, at room temperature, it mostly shows a white crystalline state, and smells with a specific odor. The melting point is between 50 and 54 degrees Celsius, and the boiling point is around 210 to 212 degrees Celsius. Because its structure contains chlorine atoms and hydroxyl groups, it is slightly soluble in water, but easily soluble in organic solvents such as ethanol and ether. This property is like that of lipids that are insoluble in water, but easy to melt in organic solvents, all because of the "similar miscibility" principle.
As for chemical properties, its hydroxyl groups have certain reactivity. It can react with bases. In the case of sodium hydroxide, the hydrogen of the hydroxyl group can be replaced by sodium to form the corresponding sodium salt. This change is similar to the reaction between acid and base neutralization. The hydrogen of the hydroxyl group is an active factor and is interchanged with the metal ions in the base. Furthermore, because of its chlorine atom, under certain conditions, the chlorine atom can be replaced by a nucleophilic reagent. For example, in the reaction with sodium alcohol, the chlorine atom can be replaced by an alkoxy group to form a new compound.
And because of the presence of the benzene ring in its structure, typical reactions of aromatic hydrocarbons can occur, such as halogenation, nitration, sulfonation, etc. In the halogenation reaction, the hydrogen on the benzene ring can be further replaced by the halogen atom under the action of the catalyst; in the nitration reaction, the nitro group can be introduced into the benzene ring under the catalysis of nitric acid and sulfuric acid; in the sulfonation reaction, the concentrated sulfuric acid can connect the benzene ring to the sulfonic acid group.
This compound has a wide range of uses in the chemical industry and is often used as a raw material for the synthesis of drugs, pesticides, dyes, etc. Its diverse chemical properties provide possibilities for many synthesis paths, just like the diverse tools in the hands of craftsmen. According to different needs, a "pavilion" of various chemical structures can be constructed.
In terms of its physical properties, at room temperature, it mostly shows a white crystalline state, and smells with a specific odor. The melting point is between 50 and 54 degrees Celsius, and the boiling point is around 210 to 212 degrees Celsius. Because its structure contains chlorine atoms and hydroxyl groups, it is slightly soluble in water, but easily soluble in organic solvents such as ethanol and ether. This property is like that of lipids that are insoluble in water, but easy to melt in organic solvents, all because of the "similar miscibility" principle.
As for chemical properties, its hydroxyl groups have certain reactivity. It can react with bases. In the case of sodium hydroxide, the hydrogen of the hydroxyl group can be replaced by sodium to form the corresponding sodium salt. This change is similar to the reaction between acid and base neutralization. The hydrogen of the hydroxyl group is an active factor and is interchanged with the metal ions in the base. Furthermore, because of its chlorine atom, under certain conditions, the chlorine atom can be replaced by a nucleophilic reagent. For example, in the reaction with sodium alcohol, the chlorine atom can be replaced by an alkoxy group to form a new compound.
And because of the presence of the benzene ring in its structure, typical reactions of aromatic hydrocarbons can occur, such as halogenation, nitration, sulfonation, etc. In the halogenation reaction, the hydrogen on the benzene ring can be further replaced by the halogen atom under the action of the catalyst; in the nitration reaction, the nitro group can be introduced into the benzene ring under the catalysis of nitric acid and sulfuric acid; in the sulfonation reaction, the concentrated sulfuric acid can connect the benzene ring to the sulfonic acid group.
This compound has a wide range of uses in the chemical industry and is often used as a raw material for the synthesis of drugs, pesticides, dyes, etc. Its diverse chemical properties provide possibilities for many synthesis paths, just like the diverse tools in the hands of craftsmen. According to different needs, a "pavilion" of various chemical structures can be constructed.
What are the physical properties of 2-bromo-1,4-dichlorobenzene?
2-% cyanogen-1,4-difluorobenzene is an organic compound with unique physical properties and is widely used in chemical, pharmaceutical and other fields. Its physical properties are as follows:
1. ** Properties **: Under normal conditions, 2-cyanogen-1,4-difluorobenzene is a colorless to light yellow liquid with a pure and specific luster in appearance and no impurities visible to the naked eye. This property is easy to observe and identify, which is of great significance for its application in industrial processes and can help practitioners intuitively judge the state and purity of the substance.
2. ** Odor **: An irritating odor, although not strong, can cause discomfort after prolonged exposure or exposure to high concentrations. It is necessary to take good protection during operation, because its smell can prompt latent risks such as leakage, to ensure the safety of personnel.
3. ** Boiling point **: The boiling point is in a specific range, about [X] ° C. This characteristic makes it possible to separate and purify 2-cyanogen-1,4-difluorobenzene by distillation and other methods. According to the difference in boiling point, it can be accurately separated from the mixture to obtain high-purity products.
4. ** Melting point **: The melting point is about [X] ° C. The temperature at which a substance changes from solid to liquid has a great impact on storage and transportation conditions. Understanding the melting point can reasonably control the ambient temperature and avoid the change of the state of the substance due to temperature changes, which affects the quality and use.
5. ** Solubility **: It has good solubility in common organic solvents such as ethanol and ether, and has low solubility in water. This property determines its solvent selection in different chemical reactions, and also affects its migration and transformation in the environment. In organic synthesis, the appropriate solvent can be selected according to the solubility to promote the reaction.
6. ** Density **: The density is about [X] g/cm ³, which is important for measurement and mixing operations. Accurately know the density, and can accurately measure a certain mass or volume of 2-cyanogen-1,4-difluorobenzene to ensure the accuracy of the experiment and production process.
7. ** Stability **: Chemical properties are stable under normal conditions, but reactions can occur under specific conditions such as high temperature, strong oxidizing agents, etc. When handling and storing, avoid exposure to these adverse conditions to ensure their quality and safety.
1. ** Properties **: Under normal conditions, 2-cyanogen-1,4-difluorobenzene is a colorless to light yellow liquid with a pure and specific luster in appearance and no impurities visible to the naked eye. This property is easy to observe and identify, which is of great significance for its application in industrial processes and can help practitioners intuitively judge the state and purity of the substance.
2. ** Odor **: An irritating odor, although not strong, can cause discomfort after prolonged exposure or exposure to high concentrations. It is necessary to take good protection during operation, because its smell can prompt latent risks such as leakage, to ensure the safety of personnel.
3. ** Boiling point **: The boiling point is in a specific range, about [X] ° C. This characteristic makes it possible to separate and purify 2-cyanogen-1,4-difluorobenzene by distillation and other methods. According to the difference in boiling point, it can be accurately separated from the mixture to obtain high-purity products.
4. ** Melting point **: The melting point is about [X] ° C. The temperature at which a substance changes from solid to liquid has a great impact on storage and transportation conditions. Understanding the melting point can reasonably control the ambient temperature and avoid the change of the state of the substance due to temperature changes, which affects the quality and use.
5. ** Solubility **: It has good solubility in common organic solvents such as ethanol and ether, and has low solubility in water. This property determines its solvent selection in different chemical reactions, and also affects its migration and transformation in the environment. In organic synthesis, the appropriate solvent can be selected according to the solubility to promote the reaction.
6. ** Density **: The density is about [X] g/cm ³, which is important for measurement and mixing operations. Accurately know the density, and can accurately measure a certain mass or volume of 2-cyanogen-1,4-difluorobenzene to ensure the accuracy of the experiment and production process.
7. ** Stability **: Chemical properties are stable under normal conditions, but reactions can occur under specific conditions such as high temperature, strong oxidizing agents, etc. When handling and storing, avoid exposure to these adverse conditions to ensure their quality and safety.
What fields are 2-bromo-1,4-dichlorobenzene used in?
2-% cyanogen-1,4-difluorobenzene is used in many fields. In the field of medicine, this compound is an important intermediate in organic synthesis. The preparation of many drugs often relies on it as a starting material and builds a key molecular framework through a series of chemical reactions. Due to its special chemical structure, it can endow drugs with unique pharmacological activities and pharmacokinetic properties, which help to improve drug efficacy and reduce side effects.
In the field of pesticides, 2-% cyanogen-1,4-difluorobenzene also plays an important role. Chemically modified pesticide products with high efficiency, low toxicity and environmental friendliness can be prepared. Its structural characteristics make it have a good inhibition and killing effect on specific pests and bacteria, and has a small impact on the environment, which is in line with the current needs of green agriculture development.
Furthermore, in the field of materials science, 2-% cyanogen-1,4-difluorobenzene can be used to synthesize special polymer materials. Introducing it into polymer structures can improve the properties of materials, such as improving the thermal stability, mechanical properties, and electrical properties of materials. Such special polymer materials are widely used in high-end fields such as electronics, aerospace, etc., such as the preparation of high-performance insulating materials, electronic packaging materials, etc.
In summary, 2-% cyanogen-1,4-difluorobenzene has important application value in the fields of medicine, pesticides and materials science, and is a key compound to promote the development of related industries.
In the field of pesticides, 2-% cyanogen-1,4-difluorobenzene also plays an important role. Chemically modified pesticide products with high efficiency, low toxicity and environmental friendliness can be prepared. Its structural characteristics make it have a good inhibition and killing effect on specific pests and bacteria, and has a small impact on the environment, which is in line with the current needs of green agriculture development.
Furthermore, in the field of materials science, 2-% cyanogen-1,4-difluorobenzene can be used to synthesize special polymer materials. Introducing it into polymer structures can improve the properties of materials, such as improving the thermal stability, mechanical properties, and electrical properties of materials. Such special polymer materials are widely used in high-end fields such as electronics, aerospace, etc., such as the preparation of high-performance insulating materials, electronic packaging materials, etc.
In summary, 2-% cyanogen-1,4-difluorobenzene has important application value in the fields of medicine, pesticides and materials science, and is a key compound to promote the development of related industries.
What is the preparation method of 2-bromo-1,4-dichlorobenzene?
To prepare 2-bromo-1,4-dichlorobenzene, the following method can be used.
Take 1,4-dichlorobenzene as the starting material, because the hydrogen atom on the benzene ring can be replaced. Place 1,4-dichlorobenzene in an appropriate reaction vessel and add an appropriate amount of liquid bromine as the bromine source. However, a catalyst is required to facilitate the reaction. The commonly used catalyst is iron filings or iron tribromide. When using iron filings, it reacts with liquid bromine to form iron tribromide, which then catalyzes the substitution reaction of 1,4-dichlorobenzene with bromine.
When reacting, it is crucial to control the reaction temperature. This reaction is generally carried out under heating conditions, so that the reaction system is maintained at an appropriate temperature range, about 50-70 ° C. If the temperature is too low, the reaction rate is slow and takes a long time; if the temperature is too high, it may initiate side reactions to form polybrominated products, resulting in a decrease in the yield of the target product.
During the reaction, liquid bromine will gradually undergo electrophilic substitution with 1,4-dichlorobenzene. Due to the fact that the chlorine atom on the benzene ring is an ortho-para-site group and the influence of steric resistance and other factors, the bromine atom mainly replaces the hydrogen atom at the ortho-site of the chlorine atom, thereby generating 2-bromo-1,4-dichlor After the
reaction, the product mixture contains unreacted raw materials, target products and possible by-products. Pure 2-bromo-1,4-dichlorobenzene can be obtained through separation and purification steps. The commonly used separation methods are distillation and column chromatography. First, distillation is used to initially separate, and most of the volatile impurities are removed by using the difference in boiling points of each component. Then column chromatography is used to achieve further separation according to the different distribution coefficients of each component between the stationary phase and the mobile phase, and finally 2-bromo-1,4-dichlorobenzene with higher purity can be obtained.
Take 1,4-dichlorobenzene as the starting material, because the hydrogen atom on the benzene ring can be replaced. Place 1,4-dichlorobenzene in an appropriate reaction vessel and add an appropriate amount of liquid bromine as the bromine source. However, a catalyst is required to facilitate the reaction. The commonly used catalyst is iron filings or iron tribromide. When using iron filings, it reacts with liquid bromine to form iron tribromide, which then catalyzes the substitution reaction of 1,4-dichlorobenzene with bromine.
When reacting, it is crucial to control the reaction temperature. This reaction is generally carried out under heating conditions, so that the reaction system is maintained at an appropriate temperature range, about 50-70 ° C. If the temperature is too low, the reaction rate is slow and takes a long time; if the temperature is too high, it may initiate side reactions to form polybrominated products, resulting in a decrease in the yield of the target product.
During the reaction, liquid bromine will gradually undergo electrophilic substitution with 1,4-dichlorobenzene. Due to the fact that the chlorine atom on the benzene ring is an ortho-para-site group and the influence of steric resistance and other factors, the bromine atom mainly replaces the hydrogen atom at the ortho-site of the chlorine atom, thereby generating 2-bromo-1,4-dichlor After the
reaction, the product mixture contains unreacted raw materials, target products and possible by-products. Pure 2-bromo-1,4-dichlorobenzene can be obtained through separation and purification steps. The commonly used separation methods are distillation and column chromatography. First, distillation is used to initially separate, and most of the volatile impurities are removed by using the difference in boiling points of each component. Then column chromatography is used to achieve further separation according to the different distribution coefficients of each component between the stationary phase and the mobile phase, and finally 2-bromo-1,4-dichlorobenzene with higher purity can be obtained.
What are the effects of 2-bromo-1,4-dichlorobenzene on the environment and humans?
2-% cyanogen-1,4-dichlorobenzene is also an organic compound. It has an impact on both the environment and human body.
At the environmental level, 2-% cyanogen-1,4-dichlorobenzene has considerable stability and is not easy to be decomposed by natural factors. If it is released into the soil, it will gradually accumulate, cause soil pollution, hinder the normal activities and reproduction of microorganisms in the soil, and then destroy the balance of the soil ecosystem. And because it has a certain water solubility, or enters the surface water with precipitation runoff, it causes water pollution and endangers aquatic organisms. If the concentration in the water exceeds a certain limit, it can cause abnormal behavior, growth inhibition, and even death of aquatic animals such as fish, destroying the diversity of aquatic ecosystems.
As for the effect on the human body, 2-% cyanogen-1,4-dichlorobenzene can enter the human body through respiratory tract, skin contact and dietary intake. After entering the body, it may cause harm to multiple organs and systems. It may irritate the mucosa of the respiratory tract, causing cough, asthma, breathing difficulties and other diseases. Long-term exposure to this substance may damage the function of the liver and kidneys. The liver is an important detoxification organ of the human body, and the kidneys excrete waste products. This substance may interfere with the normal metabolism and excretion function of the liver and kidneys, causing abnormal liver and kidney function indicators. In addition, studies have also shown that 2-% cyanogen-1,4-dichlorobenzene may be potentially carcinogenic, and long-term exposure may increase the risk of cancer. Therefore, in daily production and life, it is necessary to properly dispose of substances containing 2% cyanogen-1,4-dichlorobenzene and strengthen environmental monitoring to reduce their harm to the environment and people.
At the environmental level, 2-% cyanogen-1,4-dichlorobenzene has considerable stability and is not easy to be decomposed by natural factors. If it is released into the soil, it will gradually accumulate, cause soil pollution, hinder the normal activities and reproduction of microorganisms in the soil, and then destroy the balance of the soil ecosystem. And because it has a certain water solubility, or enters the surface water with precipitation runoff, it causes water pollution and endangers aquatic organisms. If the concentration in the water exceeds a certain limit, it can cause abnormal behavior, growth inhibition, and even death of aquatic animals such as fish, destroying the diversity of aquatic ecosystems.
As for the effect on the human body, 2-% cyanogen-1,4-dichlorobenzene can enter the human body through respiratory tract, skin contact and dietary intake. After entering the body, it may cause harm to multiple organs and systems. It may irritate the mucosa of the respiratory tract, causing cough, asthma, breathing difficulties and other diseases. Long-term exposure to this substance may damage the function of the liver and kidneys. The liver is an important detoxification organ of the human body, and the kidneys excrete waste products. This substance may interfere with the normal metabolism and excretion function of the liver and kidneys, causing abnormal liver and kidney function indicators. In addition, studies have also shown that 2-% cyanogen-1,4-dichlorobenzene may be potentially carcinogenic, and long-term exposure may increase the risk of cancer. Therefore, in daily production and life, it is necessary to properly dispose of substances containing 2% cyanogen-1,4-dichlorobenzene and strengthen environmental monitoring to reduce their harm to the environment and people.
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