Linshang Chemical
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2-Bromo-1-Chloro-3,5-Difluorobenzene
Linshang Chemical
|
HS Code |
843329 |
| Chemical Formula | C6H2BrClF2 |
| Molar Mass | 229.43 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Approx. 170 - 175 °C |
| Density | Approx. 1.85 - 1.95 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, toluene |
| Vapor Pressure | Low at room temperature |
As an accredited 2-Bromo-1-Chloro-3,5-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 2 - bromo - 1 - chloro - 3,5 - difluorobenzene, tightly sealed. |
| Storage | 2 - bromo - 1 - chloro - 3,5 - difluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage and vapor escape. Store it separately from oxidizing agents, strong acids, and bases to avoid potential chemical reactions. |
| Shipping | 2 - bromo - 1 - chloro - 3,5 - difluorobenzene, a chemical, is shipped in sealed, corrosion - resistant containers. These are carefully packaged to prevent leakage, and transported following strict hazardous material shipping regulations. |
Competitive 2-Bromo-1-Chloro-3,5-Difluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Bromo-1-Chloro-3,5-Difluorobenzene in China?
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Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Bromo-1-Chloro-3,5-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-bromo-1-chloro-3,5-difluorobenzene?
2-% hydroxyl-1-aldehyde-3,5-divinylbenzene has unique chemical properties. This substance has an aldehyde group, so it has the typical properties of an aldehyde. The aldehyde group can be oxidized, and a silver mirror reaction can occur when it encounters a weak oxidant such as silver ammonia solution. In an alkaline environment, the carbon-hydrogen bond in the aldehyde group is broken, the carbon-oxygen double bond is opened, and it reacts with silver ammonia ions to precipitate silver elemental matter to form a silver mirror. This reaction is often used to test the existence of aldehyde groups. In the case of strong oxidants such as acidic potassium permanganate solution, the aldehyde group is also oxidized, resulting in further conversion of carbon-oxygen double bonds. The product varies depending on the reaction conditions.
At the same time, its molecule contains vinyl, which gives it the properties of olefins. Addition reactions can occur, such as when it encounters bromine water, the bromine-bromine bond in the bromine elemental substance is broken, and it is respectively connected to the carbon atoms at both ends of the double bond in the vinyl group, causing the bromine water to fade. This is an important identification reaction for olefins; under certain conditions, an addition polymerization reaction can also occur, and the vinyl groups are added to each other to form a polymer compound. This reaction is widely used in the preparation of organic synthetic materials.
In addition, the presence of hydroxyl groups also affects its properties. Hydroxyl groups have certain reactivity and can participate in substitution reactions. Hydroxyl hydrogen atoms can be replaced by other atoms or atomic groups. For example, when reacting with hydrogen halide, hydroxyl groups are replaced by halogen atoms.
Due to the coexistence of multiple functional groups in its structure, each functional group affects each other, making 2-% hydroxyl-1-aldehyde-3,5-divinylbenzene rich and diverse in chemical properties, it has important application value in organic synthesis, medicinal chemistry and other fields.
At the same time, its molecule contains vinyl, which gives it the properties of olefins. Addition reactions can occur, such as when it encounters bromine water, the bromine-bromine bond in the bromine elemental substance is broken, and it is respectively connected to the carbon atoms at both ends of the double bond in the vinyl group, causing the bromine water to fade. This is an important identification reaction for olefins; under certain conditions, an addition polymerization reaction can also occur, and the vinyl groups are added to each other to form a polymer compound. This reaction is widely used in the preparation of organic synthetic materials.
In addition, the presence of hydroxyl groups also affects its properties. Hydroxyl groups have certain reactivity and can participate in substitution reactions. Hydroxyl hydrogen atoms can be replaced by other atoms or atomic groups. For example, when reacting with hydrogen halide, hydroxyl groups are replaced by halogen atoms.
Due to the coexistence of multiple functional groups in its structure, each functional group affects each other, making 2-% hydroxyl-1-aldehyde-3,5-divinylbenzene rich and diverse in chemical properties, it has important application value in organic synthesis, medicinal chemistry and other fields.
What are the main uses of 2-bromo-1-chloro-3,5-difluorobenzene?
2-% hydroxyl-1-aldehyde-3,5-divinylbenzene has a wide range of uses. In the field of chemical industry, it is often used as a key raw material for organic synthesis. Through a series of chemical reactions, many high-value-added fine chemicals can be prepared, such as fragrances with specific structures, pharmaceutical intermediates, etc. When preparing fragrances, it can impart unique odor and stability to fragrances; in the synthesis of pharmaceutical intermediates, its special chemical structure can participate in key reaction steps and help build complex drug molecular structures.
In the field of materials science, 2-% hydroxyl-1-aldehyde-3,5-divinylbenzene also plays an important role. It can be used as a polymerization monomer and copolymerized with other monomers to prepare polymer materials with specific properties. For example, copolymerization with ethylene, propylene, etc., the polymer obtained may have good mechanical properties, thermal stability and chemical stability, and is used in plastic products, fiber materials and other fields, so that the product can adapt to different environments and use needs.
Furthermore, in the coating industry, it can be used to synthesize coating resins with special properties. Due to its own structural characteristics, the coating produced may have excellent adhesion, wear resistance and chemical corrosion resistance, and is widely used in construction, automotive, marine and other industries to provide effective protection and decoration for the surface of objects.
In the electronics industry, it can be used as a raw material for electronic packaging materials. After proper processing, the packaging materials can meet the requirements of electronic products for insulation, heat resistance, and moisture resistance, ensuring the stable operation of electronic components and prolonging the service life of electronic products.
In the field of materials science, 2-% hydroxyl-1-aldehyde-3,5-divinylbenzene also plays an important role. It can be used as a polymerization monomer and copolymerized with other monomers to prepare polymer materials with specific properties. For example, copolymerization with ethylene, propylene, etc., the polymer obtained may have good mechanical properties, thermal stability and chemical stability, and is used in plastic products, fiber materials and other fields, so that the product can adapt to different environments and use needs.
Furthermore, in the coating industry, it can be used to synthesize coating resins with special properties. Due to its own structural characteristics, the coating produced may have excellent adhesion, wear resistance and chemical corrosion resistance, and is widely used in construction, automotive, marine and other industries to provide effective protection and decoration for the surface of objects.
In the electronics industry, it can be used as a raw material for electronic packaging materials. After proper processing, the packaging materials can meet the requirements of electronic products for insulation, heat resistance, and moisture resistance, ensuring the stable operation of electronic components and prolonging the service life of electronic products.
What are the synthesis methods of 2-bromo-1-chloro-3,5-difluorobenzene?
There are several methods for the synthesis of 2-% cyanogen-1-aldehyde-3,5-dienylbenzene:
First, benzene is used as the initial raw material and a functional group is introduced through a multi-step reaction. First, the benzene undergoes a Foucault acylation reaction, and anhydrous aluminum trichloride is used as a catalyst to react with a suitable acid chloride to introduce an acyl group on the benzene ring to obtain the corresponding aryl ketone. Subsequently, the α-hydrogen of aryl ketones is brominated under specific conditions by means of a halogenating agent, such as N-bromosuccinimide (NBS), to generate α-bromoaryl ketones. Then the α-bromoaryl ketone undergoes a nucleophilic substitution reaction with sodium cyanide, is dissolved in a suitable solvent such as N, N-dimethylformamide (DMF), and the reaction is heated to introduce a cyano group. Finally, through a specific aldehyde-based reagent, such as treatment with urotropine and a suitable acid under mild conditions, an aldehyde group is introduced at a suitable position, and 2-cyano1-aldehyde-3,5-dienylbenzene can be obtained through delicate multi-step transformation.
Second, a benzene derivative containing an alkenyl group is used as the starting material. If the starting benzene ring already has an alkenyl group, the alkenyl group can be converted to an appropriate functional group first. For example, by borohydrogenation-oxidation reaction, the alkenyl group is converted into an alcohol hydroxyl group, and then the alcohol hydroxyl group is converted into a suitable leaving group, such as reacting with p-toluenesulfonyl chloride to form a p-toluenesulfonate. Then, the cyanyl group is introduced by reacting with a cyanide reagent, and then the Wittig reaction or similar reaction is used to introduce the aldehyde group part under suitable conditions. After a series of steps, the synthesis of 2-cyano- 1-aldehyde-3,5-dienylbenzene is realized.
Third, the method of metal-organic chemistry is used. The halogenated benzene derivative is used as a raw material, and it is first reacted with metal magnesium to form a Grignard reagent, and then reacted with the re For example, by first reacting with a cyano-substituted halogenated hydrocarbon to introduce a cyano group, and then through a suitable metal-catalyzed reaction, such as a palladium-catalyzed coupling reaction, and an alkenylation reagent with an aldehyde group, the target product 2-cyanogen-1-aldehyde-3,5-dienylbenzene can also be synthesized by reasonably designing the reaction sequence and conditions. This method has its own advantages and disadvantages, and it needs to be selected according to actual needs and conditions.
First, benzene is used as the initial raw material and a functional group is introduced through a multi-step reaction. First, the benzene undergoes a Foucault acylation reaction, and anhydrous aluminum trichloride is used as a catalyst to react with a suitable acid chloride to introduce an acyl group on the benzene ring to obtain the corresponding aryl ketone. Subsequently, the α-hydrogen of aryl ketones is brominated under specific conditions by means of a halogenating agent, such as N-bromosuccinimide (NBS), to generate α-bromoaryl ketones. Then the α-bromoaryl ketone undergoes a nucleophilic substitution reaction with sodium cyanide, is dissolved in a suitable solvent such as N, N-dimethylformamide (DMF), and the reaction is heated to introduce a cyano group. Finally, through a specific aldehyde-based reagent, such as treatment with urotropine and a suitable acid under mild conditions, an aldehyde group is introduced at a suitable position, and 2-cyano1-aldehyde-3,5-dienylbenzene can be obtained through delicate multi-step transformation.
Second, a benzene derivative containing an alkenyl group is used as the starting material. If the starting benzene ring already has an alkenyl group, the alkenyl group can be converted to an appropriate functional group first. For example, by borohydrogenation-oxidation reaction, the alkenyl group is converted into an alcohol hydroxyl group, and then the alcohol hydroxyl group is converted into a suitable leaving group, such as reacting with p-toluenesulfonyl chloride to form a p-toluenesulfonate. Then, the cyanyl group is introduced by reacting with a cyanide reagent, and then the Wittig reaction or similar reaction is used to introduce the aldehyde group part under suitable conditions. After a series of steps, the synthesis of 2-cyano- 1-aldehyde-3,5-dienylbenzene is realized.
Third, the method of metal-organic chemistry is used. The halogenated benzene derivative is used as a raw material, and it is first reacted with metal magnesium to form a Grignard reagent, and then reacted with the re For example, by first reacting with a cyano-substituted halogenated hydrocarbon to introduce a cyano group, and then through a suitable metal-catalyzed reaction, such as a palladium-catalyzed coupling reaction, and an alkenylation reagent with an aldehyde group, the target product 2-cyanogen-1-aldehyde-3,5-dienylbenzene can also be synthesized by reasonably designing the reaction sequence and conditions. This method has its own advantages and disadvantages, and it needs to be selected according to actual needs and conditions.
What should I pay attention to when storing and transporting 2-bromo-1-chloro-3,5-difluorobenzene?
2-% hydroxyl-1-aldehyde-3,5-divinylbenzene, which is a chemical material, many matters need to be carefully paid attention to during storage and transportation.
The first word storage. First, the temperature and humidity must be properly controlled. This material may be affected by temperature and humidity, resulting in its quality variation. Therefore, it should be stored in a cool, dry and well-ventilated place, away from direct sunlight and heat sources. If the temperature is too high, it may cause the material to evaporate and decompose; if the humidity is too high, it may cause deliquescence and deterioration. Second, the storage place should be away from fire, heat sources and oxidants. Because of its flammability, in case of open flame, high heat can cause the risk of combustion and explosion; and oxidant contact with it, or cause violent chemical reaction, endangering safety. Third, should be classified storage, do not mix with acid, alkali and other substances. Because of its active chemical properties, encounter with acid and alkali, or produce unpredictable reactions, damage the material and lead to disaster.
Second on transportation. First, the means of transportation must be clean, dry and free of impurities. If the means of transportation are unclean and impurities are mixed into the material, its quality will be degraded. Second, during transportation, it is necessary to prevent exposure to the sun, rain and high temperature. In summer high temperature, it is advisable to choose morning and evening transportation; in case of rain, it should be properly shaded to prevent the material from being flooded. Third, transportation personnel should be professionally trained and familiar with material characteristics and emergency response methods. Once there is a change on the way, such as leakage, they can respond quickly and properly to minimize the damage.
In short, the storage and transportation of 2-% hydroxyl-1-aldehyde-3,5-divinylbenzene is related to safety and quality. All links should not be ignored. It must be carried out in accordance with regulations to ensure safety.
The first word storage. First, the temperature and humidity must be properly controlled. This material may be affected by temperature and humidity, resulting in its quality variation. Therefore, it should be stored in a cool, dry and well-ventilated place, away from direct sunlight and heat sources. If the temperature is too high, it may cause the material to evaporate and decompose; if the humidity is too high, it may cause deliquescence and deterioration. Second, the storage place should be away from fire, heat sources and oxidants. Because of its flammability, in case of open flame, high heat can cause the risk of combustion and explosion; and oxidant contact with it, or cause violent chemical reaction, endangering safety. Third, should be classified storage, do not mix with acid, alkali and other substances. Because of its active chemical properties, encounter with acid and alkali, or produce unpredictable reactions, damage the material and lead to disaster.
Second on transportation. First, the means of transportation must be clean, dry and free of impurities. If the means of transportation are unclean and impurities are mixed into the material, its quality will be degraded. Second, during transportation, it is necessary to prevent exposure to the sun, rain and high temperature. In summer high temperature, it is advisable to choose morning and evening transportation; in case of rain, it should be properly shaded to prevent the material from being flooded. Third, transportation personnel should be professionally trained and familiar with material characteristics and emergency response methods. Once there is a change on the way, such as leakage, they can respond quickly and properly to minimize the damage.
In short, the storage and transportation of 2-% hydroxyl-1-aldehyde-3,5-divinylbenzene is related to safety and quality. All links should not be ignored. It must be carried out in accordance with regulations to ensure safety.
What are the effects of 2-bromo-1-chloro-3,5-difluorobenzene on the environment and human health?
2-% cyanogen-1-chloro-3,5-difluorobenzene has various effects on the environment and human health.
At one end of the environment, this substance has a certain stability, is difficult to degrade naturally, or remains in the environment for a long time. It can migrate through water, soil, atmosphere and other media. If released in water or ingested by aquatic organisms, it will cause accumulation in organisms and pass through the food chain, endangering upper-level organisms. And in soil, it may affect the structure and function of soil microbial community, disturb the balance of soil ecosystem, and then damage plant growth and development.
As for human health, this substance may enter the body through respiration, skin contact, dietary intake, etc. It has certain toxicity, or irritates the eyes, respiratory tract, skin and other parts. Long-term exposure, or damage the nervous system, causing headache, dizziness, fatigue, insomnia and other symptoms. It may also involve organs such as the liver and kidneys, affecting the normal function of organs. Furthermore, there may be a potential carcinogenic risk. Although relevant studies are not fully clear, this possibility should not be ignored.
Therefore, when producing and using products containing 2% cyanogen-1-chloro-3,5-difluorobenzene, it is necessary to strictly abide by safety regulations and environmental protection standards to prevent it from causing adverse effects on the environment and human health.
At one end of the environment, this substance has a certain stability, is difficult to degrade naturally, or remains in the environment for a long time. It can migrate through water, soil, atmosphere and other media. If released in water or ingested by aquatic organisms, it will cause accumulation in organisms and pass through the food chain, endangering upper-level organisms. And in soil, it may affect the structure and function of soil microbial community, disturb the balance of soil ecosystem, and then damage plant growth and development.
As for human health, this substance may enter the body through respiration, skin contact, dietary intake, etc. It has certain toxicity, or irritates the eyes, respiratory tract, skin and other parts. Long-term exposure, or damage the nervous system, causing headache, dizziness, fatigue, insomnia and other symptoms. It may also involve organs such as the liver and kidneys, affecting the normal function of organs. Furthermore, there may be a potential carcinogenic risk. Although relevant studies are not fully clear, this possibility should not be ignored.
Therefore, when producing and using products containing 2% cyanogen-1-chloro-3,5-difluorobenzene, it is necessary to strictly abide by safety regulations and environmental protection standards to prevent it from causing adverse effects on the environment and human health.
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