Linshang Chemical
PRODUCTS
2-Bromo-1-Chloro-3-Fluorobenzene
Linshang Chemical
|
HS Code |
350263 |
| Chemical Formula | C6H3BrClF |
| Molecular Weight | 211.44 |
| Appearance | Liquid (usually) |
| Boiling Point | Data may vary, around 190 - 200°C approximately |
| Density | Typically around 1.7 - 1.8 g/cm³ (estimated) |
| Solubility In Water | Insoluble (organic compound, non - polar) |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone, toluene |
| Vapor Pressure | Low vapor pressure at room temperature |
| Odor | Typical organic halogen - containing compound odor (pungent) |
As an accredited 2-Bromo-1-Chloro-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2 - bromo - 1 - chloro - 3 - fluorobenzene packaged in a sealed glass bottle. |
| Storage | Store 2 - bromo - 1 - chloro - 3 - fluorobenzene in a cool, well - ventilated area, away from heat, sparks, and open flames as it is potentially flammable. Keep it in a tightly sealed container to prevent vapor leakage. Avoid storage near oxidizing agents. Label the container clearly for easy identification and ensure compliance with local chemical storage regulations. |
| Shipping | 2 - bromo - 1 - chloro - 3 - fluorobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations to ensure safety during transit, avoiding exposure to heat, moisture, and incompatible substances. |
Competitive 2-Bromo-1-Chloro-3-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Bromo-1-Chloro-3-Fluorobenzene in China?
As a trusted 2-Bromo-1-Chloro-3-Fluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Bromo-1-Chloro-3-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-bromo-1-chloro-3-fluorobenzene?
2-% -1-nitrate-3-nitrate sand, it is used to make. 2-% nitrate, the taste is cold, the ancestors of ancient times, used to make the taste, make the taste mellow, and can be antiseptic, and the contents will not rot for a long time. And in the road, it can be used as a guide, to help the power of the car, and it can also be washed externally.
1-nitrate, the nature is bitter and cold. In the case of pyrotechnics, it is the important thing for making fire, and in the case of fire, it can be used for travel and attack, equipment and shooting, which is very powerful. And in the case of metallurgy, it can melt stone, extract refined gold, and help the smelting power.
3-sand, the use of prosperity. In the process of making pottery, it can be used as a glaze, so that the color of the pottery is high, and the ground is dense. In the process of making food, it can make the cake and make it delicious.
Of the three, 2-%, 1-nitrate, 3-nitrate sand, or food for people's livelihood, or involved in travel equipment, or used in hundreds of industrial techniques, are all indispensable things in the world, and their contributions are great. They are used in the world, and the lives of the people are deeply affected.
1-nitrate, the nature is bitter and cold. In the case of pyrotechnics, it is the important thing for making fire, and in the case of fire, it can be used for travel and attack, equipment and shooting, which is very powerful. And in the case of metallurgy, it can melt stone, extract refined gold, and help the smelting power.
3-sand, the use of prosperity. In the process of making pottery, it can be used as a glaze, so that the color of the pottery is high, and the ground is dense. In the process of making food, it can make the cake and make it delicious.
Of the three, 2-%, 1-nitrate, 3-nitrate sand, or food for people's livelihood, or involved in travel equipment, or used in hundreds of industrial techniques, are all indispensable things in the world, and their contributions are great. They are used in the world, and the lives of the people are deeply affected.
What are the synthesis methods of 2-bromo-1-chloro-3-fluorobenzene?
To prepare 2-alkynyl-1-aldehyde-3-allyl alcohol, the following methods are used:
First, propargyl alcohol and formate are used as raw materials to react under basic conditions. In this reaction, the hydroxyl nucleophilic group of propargyl alcohol attacks the carbonyl carbon of the formate, and then leaves the methoxy negative ion, and the target product can be obtained through proton transfer and other steps. Sodium alcohol is often selected as a base, which promotes the formation of nucleophilic reagents in the reaction and improves the reaction activity.
Second, propargyl aldehyde and allyl halide are used as starting materials to react in the presence of metal catalysts and bases. Metal catalysts such as palladium can be oxidized with allyl halides to form active intermediates, while bases activate alpha-hydrogen of propionyl aldehyde, making it easier to undergo nucleophilic substitution reaction with active intermediates, thereby generating 2-alkynyl-1-aldehyde-3-allyl alcohol.
Third, starting from suitable alkynyl alcohol, it is prepared by selective oxidation reaction. If a mild oxidizing agent is used, under specific conditions, the terminal hydroxyl group of alkynyl alcohol is selectively oxidized to an aldehyde group, and the structure of alkynyl and allyl groups is not affected. Diess-Martin oxidizing agent (DMP) can be selected to react in a suitable organic solvent. This process requires precise control of the reaction conditions to ensure the selectivity and yield of the reaction.
Fourth, the alkynyl lithium reagent is reacted with allyl aldehyde, and then after appropriate post-treatment. The alkynyl lithium reagent performs nucleophilic addition to the carbonyl group of allyl aldehyde to form an alcohol salt intermediate, and then the target product can be obtained through post-treatment steps such as acidification. However, the alkynyl lithium reagent has high activity and requires harsh reaction conditions. It needs to be operated in a low temperature and anhydrous environment.
These methods have their own advantages and disadvantages. In practical application, the appropriate synthesis method should be carefully selected according to factors such as the availability of raw materials, the difficulty of controlling the reaction conditions, and the purity requirements of the target product.
First, propargyl alcohol and formate are used as raw materials to react under basic conditions. In this reaction, the hydroxyl nucleophilic group of propargyl alcohol attacks the carbonyl carbon of the formate, and then leaves the methoxy negative ion, and the target product can be obtained through proton transfer and other steps. Sodium alcohol is often selected as a base, which promotes the formation of nucleophilic reagents in the reaction and improves the reaction activity.
Second, propargyl aldehyde and allyl halide are used as starting materials to react in the presence of metal catalysts and bases. Metal catalysts such as palladium can be oxidized with allyl halides to form active intermediates, while bases activate alpha-hydrogen of propionyl aldehyde, making it easier to undergo nucleophilic substitution reaction with active intermediates, thereby generating 2-alkynyl-1-aldehyde-3-allyl alcohol.
Third, starting from suitable alkynyl alcohol, it is prepared by selective oxidation reaction. If a mild oxidizing agent is used, under specific conditions, the terminal hydroxyl group of alkynyl alcohol is selectively oxidized to an aldehyde group, and the structure of alkynyl and allyl groups is not affected. Diess-Martin oxidizing agent (DMP) can be selected to react in a suitable organic solvent. This process requires precise control of the reaction conditions to ensure the selectivity and yield of the reaction.
Fourth, the alkynyl lithium reagent is reacted with allyl aldehyde, and then after appropriate post-treatment. The alkynyl lithium reagent performs nucleophilic addition to the carbonyl group of allyl aldehyde to form an alcohol salt intermediate, and then the target product can be obtained through post-treatment steps such as acidification. However, the alkynyl lithium reagent has high activity and requires harsh reaction conditions. It needs to be operated in a low temperature and anhydrous environment.
These methods have their own advantages and disadvantages. In practical application, the appropriate synthesis method should be carefully selected according to factors such as the availability of raw materials, the difficulty of controlling the reaction conditions, and the purity requirements of the target product.
What are the physical properties of 2-bromo-1-chloro-3-fluorobenzene?
The physical properties of 2-% 1-alkane-3-enyne can be described.
First, under normal conditions, the low carbon content of 2-% 1-alkane-3-enyne is mostly low. The increase in carbon is due to the increase in liquid, while the high carbon content is due to the solidification. Such as methane and ethane derivatives, which are often used. However, if there is a little more carbon, the liquid will flow, and if there is a compound, the shape will be solid.
Second, it will melt. Due to the action force of the molecule, the melting boiling of 2-% 1-alkane-3-enyne, its carbon and atomic phase. The more carbon, the more the dispersion force of the molecule, and the increase of the melting force. And the existence of the atom, because of the high resistance of the atom, can make the molecule grow, and increase the molecular force, causing the melting to increase. Such as fluorine-containing 2-% 1-alkane-3-enyne, because the fluorine atom has a high resistance, the melting boiling has a higher concentration of other atoms.
Furthermore, the solubility. 2-% -1-alkane-3-alkenyne is slightly soluble due to the presence of alkenyl and alkenyl atoms, but the non-alkenyl part also has a phase ratio. Therefore, its solubility in water is very small, and the solubility of water is low, and the solubility of this compound is not enough to form a good interaction with water. On the contrary, in non-soluble or weak solubility, such as ether, carbon tetrachloride, etc., the solubility is good, so it is "similar to miscibility".
and its density. Generally speaking, due to the large atomic weight of the atom, the density of 2-% -1-alkane-3-alkenyne is larger than that of the alkenyl phase. And the atomic weight increases, the density also increases. For example, derivatives containing bromine and iodine often have a density greater than that of water, while those containing chlorine have a density greater than that of alkanes. Therefore, the physical properties of 2-% 1-alkane-3-alkenyne are affected by factors such as carbon atoms and atom atoms in them, and they exhibit similar characteristics.
First, under normal conditions, the low carbon content of 2-% 1-alkane-3-enyne is mostly low. The increase in carbon is due to the increase in liquid, while the high carbon content is due to the solidification. Such as methane and ethane derivatives, which are often used. However, if there is a little more carbon, the liquid will flow, and if there is a compound, the shape will be solid.
Second, it will melt. Due to the action force of the molecule, the melting boiling of 2-% 1-alkane-3-enyne, its carbon and atomic phase. The more carbon, the more the dispersion force of the molecule, and the increase of the melting force. And the existence of the atom, because of the high resistance of the atom, can make the molecule grow, and increase the molecular force, causing the melting to increase. Such as fluorine-containing 2-% 1-alkane-3-enyne, because the fluorine atom has a high resistance, the melting boiling has a higher concentration of other atoms.
Furthermore, the solubility. 2-% -1-alkane-3-alkenyne is slightly soluble due to the presence of alkenyl and alkenyl atoms, but the non-alkenyl part also has a phase ratio. Therefore, its solubility in water is very small, and the solubility of water is low, and the solubility of this compound is not enough to form a good interaction with water. On the contrary, in non-soluble or weak solubility, such as ether, carbon tetrachloride, etc., the solubility is good, so it is "similar to miscibility".
and its density. Generally speaking, due to the large atomic weight of the atom, the density of 2-% -1-alkane-3-alkenyne is larger than that of the alkenyl phase. And the atomic weight increases, the density also increases. For example, derivatives containing bromine and iodine often have a density greater than that of water, while those containing chlorine have a density greater than that of alkanes. Therefore, the physical properties of 2-% 1-alkane-3-alkenyne are affected by factors such as carbon atoms and atom atoms in them, and they exhibit similar characteristics.
What are the precautions for storing and transporting 2-bromo-1-chloro-3-fluorobenzene?
2-% E6% BA% B4 - 1-% E6% B0% AF - 3-%E6%B0%9F%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E8%BF%87%E7%A8%8B%E4%B8%AD%EF%BC%8C%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E4%B8%8B%E5%88%97%E4%BA%8B%E9%A1%B9%EF%BC%9A
** First, when storing **
1. ** Moisture-proof and moisture-proof **: These three are susceptible to moisture intrusion, when looking for a dry place to hide. If placed in a damp place, 2-% E6% BA% B4 is prone to rust and damage its texture; 1-% E6% B0% AF or due to water vapor infiltration, change its properties; 3-%E6%B0%9F%E8%8B%AF will also be damp and moldy, lose its effectiveness.
2. ** Classified storage **: The three have different physical properties and cannot be mixed. 2-% E6% BA% B4 is hard in texture, or will damage 1-% E6% B0% AF and 3-%E6%B0%9F%E8%8B%AF; and different substances, different chemical properties, stored in the same place or lead to chemical reactions, resulting in quality deterioration.
3. ** Temperature suitable **: temperature is too high or too low, are unfavorable. Under high temperature, 1-% E6% B0% AF or volatilization intensifies, 2-% E6% BA% B4 thermal expansion and contraction, or deformation; at low temperature, 3-%E6%B0%9F%E8%8B%AF or freezing qualitative change, affecting subsequent use.
** 2. During transportation **
1. ** Packaging is stable **: In order to prevent collision damage during transportation, a solid packaging is required. 2-% E6% BA% B4 should be filled in a thick wood or metal box with soft cushions; 1-% E6% B0% AF should be sealed in a sealed container and wrapped in shock-proof materials; 3-%E6%B0%9F%E8%8B%AF should ensure that the packaging is waterproof, moisture-proof and has a cushioning function.
2. ** Avoid bumps **: The driving route should be smooth. Violent bumps or 2-% E6% BA% B4 impact and deform each other, 1-% E6% B0% AF containers are damaged and leaked, 3-%E6%B0%9F%E8%8B%AF packaging is broken and damaged. Transporters should drive slowly to avoid potholes and bumpy roads.
3. ** compliance Transportation **: All three or involve special transportation regulations, and must follow the regulations. Transport 1-% E6% B0% AF and 2-% E6% BA% B4, it is necessary to check whether they are dangerous goods, in accordance with the relevant transportation laws; 3-%E6%B0%9F%E8%8B%AF or there may be specific transportation requirements, not negligent, to ensure transportation safety.
** First, when storing **
1. ** Moisture-proof and moisture-proof **: These three are susceptible to moisture intrusion, when looking for a dry place to hide. If placed in a damp place, 2-% E6% BA% B4 is prone to rust and damage its texture; 1-% E6% B0% AF or due to water vapor infiltration, change its properties; 3-%E6%B0%9F%E8%8B%AF will also be damp and moldy, lose its effectiveness.
2. ** Classified storage **: The three have different physical properties and cannot be mixed. 2-% E6% BA% B4 is hard in texture, or will damage 1-% E6% B0% AF and 3-%E6%B0%9F%E8%8B%AF; and different substances, different chemical properties, stored in the same place or lead to chemical reactions, resulting in quality deterioration.
3. ** Temperature suitable **: temperature is too high or too low, are unfavorable. Under high temperature, 1-% E6% B0% AF or volatilization intensifies, 2-% E6% BA% B4 thermal expansion and contraction, or deformation; at low temperature, 3-%E6%B0%9F%E8%8B%AF or freezing qualitative change, affecting subsequent use.
** 2. During transportation **
1. ** Packaging is stable **: In order to prevent collision damage during transportation, a solid packaging is required. 2-% E6% BA% B4 should be filled in a thick wood or metal box with soft cushions; 1-% E6% B0% AF should be sealed in a sealed container and wrapped in shock-proof materials; 3-%E6%B0%9F%E8%8B%AF should ensure that the packaging is waterproof, moisture-proof and has a cushioning function.
2. ** Avoid bumps **: The driving route should be smooth. Violent bumps or 2-% E6% BA% B4 impact and deform each other, 1-% E6% B0% AF containers are damaged and leaked, 3-%E6%B0%9F%E8%8B%AF packaging is broken and damaged. Transporters should drive slowly to avoid potholes and bumpy roads.
3. ** compliance Transportation **: All three or involve special transportation regulations, and must follow the regulations. Transport 1-% E6% B0% AF and 2-% E6% BA% B4, it is necessary to check whether they are dangerous goods, in accordance with the relevant transportation laws; 3-%E6%B0%9F%E8%8B%AF or there may be specific transportation requirements, not negligent, to ensure transportation safety.
What are the effects of 2-bromo-1-chloro-3-fluorobenzene on the environment and human health?
2-% mercury-1-% arsenic-3-% mercury cyanide has a significant impact on human health. Mercury is a heavy metal and is widely distributed in the natural environment. When it enters the human body, it can damage many organs, especially the mind. Young children are especially sensitive to its toxicity. Mercury contaminates water sources, which can be caused by water and food, endangering human health.
Arsenic is also a poison. Exposure to arsenic-containing environments can cause skin diseases, cardiovascular diseases, and even cancer. The accumulation of arsenic in soil can affect plant life, and it can be caused by food, endangering human health.
Mercury cyanide toxicity, its entry into the environment, can quickly pollute soil and water sources. A small amount of mercury cyanide can cause poisoning, and in severe cases it can cause death. And mercury cyanide can be degraded in the environment, and the health balance of the environment can be damaged.
Of course, 2-% mercury-1-% arsenic-3-% mercury cyanide is harmful to human health. The urgent need is to control the release of this poison in the environment to ensure the safety of the environment and the health of the human body. All parties need to work together to take effective measures to prevent these poisons from causing greater harm to people in the environment.
Arsenic is also a poison. Exposure to arsenic-containing environments can cause skin diseases, cardiovascular diseases, and even cancer. The accumulation of arsenic in soil can affect plant life, and it can be caused by food, endangering human health.
Mercury cyanide toxicity, its entry into the environment, can quickly pollute soil and water sources. A small amount of mercury cyanide can cause poisoning, and in severe cases it can cause death. And mercury cyanide can be degraded in the environment, and the health balance of the environment can be damaged.
Of course, 2-% mercury-1-% arsenic-3-% mercury cyanide is harmful to human health. The urgent need is to control the release of this poison in the environment to ensure the safety of the environment and the health of the human body. All parties need to work together to take effective measures to prevent these poisons from causing greater harm to people in the environment.
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