Linshang Chemical
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2-Bromo-1-Chloro-4-Fluorobenzene
Linshang Chemical
|
HS Code |
474933 |
| Chemical Formula | C6H3BrClF |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 185 - 187 °C |
| Density | 1.708 g/cm³ |
| Flash Point | 75 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Refractive Index | 1.556 - 1.558 |
As an accredited 2-Bromo-1-Chloro-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 2 - bromo - 1 - chloro - 4 - fluorobenzene in a sealed glass bottle. |
| Storage | 2 - bromo - 1 - chloro - 4 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Separate it from oxidizing agents and incompatible substances to prevent potential reactions. Label the storage clearly for easy identification. |
| Shipping | 2 - bromo - 1 - chloro - 4 - fluorobenzene is shipped in well - sealed, corrosion - resistant containers. These are carefully packaged to prevent leakage during transit, following strict chemical shipping regulations to ensure safety. |
Competitive 2-Bromo-1-Chloro-4-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Bromo-1-Chloro-4-Fluorobenzene in China?
As a trusted 2-Bromo-1-Chloro-4-Fluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Bromo-1-Chloro-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-bromo-1-chloro-4-fluorobenzene?
The main user of 2-%-1-nitrate-4-cane, because of its unique characteristics, has special effects in all domains.
First in the domains of the world, its effect is very great. 2-%-1-nitrate-4-cane contains general chemical ingredients, which can be used as raw materials for the world. There are ancient Chinese books that have been used for a long time, and they can be used to reduce blood stasis and eliminate stasis. In case of bruises and pain in the limbs, use this exquisite combination to apply it to the patient, which can activate the blood and make the pain disappear. And in the way of taking it, it can be used to harmonize the organs, and it can also solve some diseases.
Furthermore, in the realm of industrial beauty, 2-%-1-nitrate-4-rattan can also have a place. Because of its unique color, it can be used for raw materials. Those who use it can get a long-lasting color. The ancient Danqing wonderful hand, often weighs on this, and it is easy to use it on the surface of the river, and its color is still bright as ever. And in the lacquer work, adding 2-%-1-nitrate-4-rattan can make the color of the lacquer deeper and add the beauty of the utensils.
And in the,% 2-1-nitrate-4-rattan is also wonderful. It can be used as a natural gas, and it has the effect of avoiding certain pests. With its large amount of liquid, it can not only protect crops from invasion, but also eliminate the disadvantages of natural gas.
In this way, 2-%-1-nitrate-4-cane is used in natural gas, industrial beauty, and general fields. They are all important functions, and they are the treasures of heaven and earth.
First in the domains of the world, its effect is very great. 2-%-1-nitrate-4-cane contains general chemical ingredients, which can be used as raw materials for the world. There are ancient Chinese books that have been used for a long time, and they can be used to reduce blood stasis and eliminate stasis. In case of bruises and pain in the limbs, use this exquisite combination to apply it to the patient, which can activate the blood and make the pain disappear. And in the way of taking it, it can be used to harmonize the organs, and it can also solve some diseases.
Furthermore, in the realm of industrial beauty, 2-%-1-nitrate-4-rattan can also have a place. Because of its unique color, it can be used for raw materials. Those who use it can get a long-lasting color. The ancient Danqing wonderful hand, often weighs on this, and it is easy to use it on the surface of the river, and its color is still bright as ever. And in the lacquer work, adding 2-%-1-nitrate-4-rattan can make the color of the lacquer deeper and add the beauty of the utensils.
And in the,% 2-1-nitrate-4-rattan is also wonderful. It can be used as a natural gas, and it has the effect of avoiding certain pests. With its large amount of liquid, it can not only protect crops from invasion, but also eliminate the disadvantages of natural gas.
In this way, 2-%-1-nitrate-4-cane is used in natural gas, industrial beauty, and general fields. They are all important functions, and they are the treasures of heaven and earth.
What are the physical properties of 2-bromo-1-chloro-4-fluorobenzene?
The physical properties of 2-% salt-1-base-4-ether sulfone are as follows:
Salts are mostly crystalline and have a regular geometric shape. Common salts are hard and brittle at room temperature. Its melting and boiling points are quite high, because ionic bonds bind ions, and more energy is required to separate them. Solubility varies, such as sodium chloride, potassium chloride, etc. are easily soluble in water and dispersed in ionic states; while barium sulfate, silver chloride, etc. are insoluble in water. Its aqueous solution or molten state can conduct electricity, because it has free-moving ions, which is the characteristic of electrolytes.
Alkali, the appearance is often solid, and sodium hydroxide, potassium hydroxide, etc. are white lumps or flakes. Its texture may be soft or hard, depending on the specific type. Alkali has a slippery and greasy feel, and has a special texture when touched. Easily soluble in water, when dissolved, it will exothermic, such as sodium hydroxide dissolved in water, the solution temperature rises significantly. Its aqueous solution is alkaline, which can turn the phenolphthalein test solution red and the litmus test solution blue. It can neutralize with acids to form salts and water.
Ether sulfone is an organic compound, mostly solid or liquid at room temperature. Solid is relatively brittle in texture, and liquid has a certain fluidity. The melting point and boiling point of ether sulfone vary depending on the structure. Its chemical stability is good, and it is inert to most chemical reagents. In terms of solubility, some ether sulfone is soluble in organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., but insoluble in water, due to the difference between molecular polarity and water molecules. And ether sulfone has good thermal stability and is not easy to decompose at high temperature. It is widely used in many industrial fields because of this characteristic.
Salts are mostly crystalline and have a regular geometric shape. Common salts are hard and brittle at room temperature. Its melting and boiling points are quite high, because ionic bonds bind ions, and more energy is required to separate them. Solubility varies, such as sodium chloride, potassium chloride, etc. are easily soluble in water and dispersed in ionic states; while barium sulfate, silver chloride, etc. are insoluble in water. Its aqueous solution or molten state can conduct electricity, because it has free-moving ions, which is the characteristic of electrolytes.
Alkali, the appearance is often solid, and sodium hydroxide, potassium hydroxide, etc. are white lumps or flakes. Its texture may be soft or hard, depending on the specific type. Alkali has a slippery and greasy feel, and has a special texture when touched. Easily soluble in water, when dissolved, it will exothermic, such as sodium hydroxide dissolved in water, the solution temperature rises significantly. Its aqueous solution is alkaline, which can turn the phenolphthalein test solution red and the litmus test solution blue. It can neutralize with acids to form salts and water.
Ether sulfone is an organic compound, mostly solid or liquid at room temperature. Solid is relatively brittle in texture, and liquid has a certain fluidity. The melting point and boiling point of ether sulfone vary depending on the structure. Its chemical stability is good, and it is inert to most chemical reagents. In terms of solubility, some ether sulfone is soluble in organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., but insoluble in water, due to the difference between molecular polarity and water molecules. And ether sulfone has good thermal stability and is not easy to decompose at high temperature. It is widely used in many industrial fields because of this characteristic.
What are the chemical properties of 2-bromo-1-chloro-4-fluorobenzene?
In the case of 2-% N-1-nitrate-4-ether alcohol, its chemical properties are special, as described below.
In the case of 2-% N, the sexual activity is low, and it is often low. In case of gold, it can cause many reactions, and it is low. If it is placed in 2-% N, it will be high in the bubble, and it will escape from the water, and it will dissolve and form a liquid. In the process of melting, it should also be low, helping to promote the reaction, such as the replacement of alcohol, 2-% N can be catalyzed.
1-nitrate, it is high in oxidation. When it comes to combustible materials, it is easy to cause ignition and explosion, and it is difficult to produce. When 1-nitrate encounters gold, it often melts, but when it encounters active gold, such as gold, nitrogen, etc., it adds a strong reaction, forming a phase of nitric acid, nitrogen oxides and water. When there is a substance that encounters 1-nitrate, it is also easy to be oxidized, and its reaction is high, or the cause is high, and the property is also high.
4-ether alcohols have the properties of ether alcohols. Its ether group, however, can be cracked and reversed under special conditions. The alcohol group makes 4-ether alcohols have the general properties of alcohols, such as anti-alcohol, and can be esterified. And 4-ether alcohols have the properties of other ethers and alcohols due to their molecular properties, boiling, solubility, etc. Its solubility is good, it can be used as a solvent, containing chemical and chemical substances, and it can be used in chemical synthesis, analysis, and other fields.
It is necessary that 2-%, 1-nitrate, and 4-ether alcohols each have special properties, and they can be used in chemical fields. Research and use can promote chemical steps, and then use it carefully to prevent damage.
In the case of 2-% N, the sexual activity is low, and it is often low. In case of gold, it can cause many reactions, and it is low. If it is placed in 2-% N, it will be high in the bubble, and it will escape from the water, and it will dissolve and form a liquid. In the process of melting, it should also be low, helping to promote the reaction, such as the replacement of alcohol, 2-% N can be catalyzed.
1-nitrate, it is high in oxidation. When it comes to combustible materials, it is easy to cause ignition and explosion, and it is difficult to produce. When 1-nitrate encounters gold, it often melts, but when it encounters active gold, such as gold, nitrogen, etc., it adds a strong reaction, forming a phase of nitric acid, nitrogen oxides and water. When there is a substance that encounters 1-nitrate, it is also easy to be oxidized, and its reaction is high, or the cause is high, and the property is also high.
4-ether alcohols have the properties of ether alcohols. Its ether group, however, can be cracked and reversed under special conditions. The alcohol group makes 4-ether alcohols have the general properties of alcohols, such as anti-alcohol, and can be esterified. And 4-ether alcohols have the properties of other ethers and alcohols due to their molecular properties, boiling, solubility, etc. Its solubility is good, it can be used as a solvent, containing chemical and chemical substances, and it can be used in chemical synthesis, analysis, and other fields.
It is necessary that 2-%, 1-nitrate, and 4-ether alcohols each have special properties, and they can be used in chemical fields. Research and use can promote chemical steps, and then use it carefully to prevent damage.
What are the synthesis methods of 2-bromo-1-chloro-4-fluorobenzene?
The synthesis of 2-% hydrocarbon-1-alkyne-4-alkenylbenzene has various approaches, which are described in detail as follows:
First, it can be achieved by the coupling reaction of alkynes and halogenated aromatics. Select suitable active halogenated aromatics, such as brominated or iodobenzene derivatives, and react with alkynyl-containing compounds in a suitable solvent in the presence of palladium, copper and other metal catalysts and ligands. If a palladium catalyst is used, tetrakis (triphenylphosphine) palladium (0) is often selected, and copper salts can be selected from cuprous iodide. The ligand can be triethylamine, etc., in an organic solvent such as dichloromethane, N, N-dimethylformamide, stirred at a moderate temperature, and after metal-catalyzed oxidation addition, transmetallization and reduction elimination steps, the target 2-% hydrocarbon-1-alkynyl-4-alkenylbenzene can be generated.
Second, the strategy of alkenylation reaction is adopted. First, an alkenyl intermediate containing a specific substituent is prepared, and alkenyl borate or alkenyl halide is used as raw material to react with alkynylbenzene derivatives under basic conditions and metal catalysis. For example, under the catalysis of alkenyl borate and alkynyl benzene in bases such as potassium carbonate and tetrakis (triphenylphosphine) palladium (0), the reaction is heated in a dioxane-water mixed solvent, and the boron atom is metallized with the aryl group of alkynyl benzene, and then eliminated by oxidative addition and reduction to construct the required carbon-carbon bond to achieve the synthesis of 2-% hydrocarbon-1-alkynyl-4-alkenyl benzene.
Third, the cyclization reaction catalyzed by transition metals is used. Take an appropriate chain precursor, containing alkenyl, alkynyl and phenyl ring structural units, and under the action of a transition metal catalyst, an intramolecular cyclization reaction occurs. For example, using metal catalysts such as rhodium or ruthenium, under mild conditions, cyclization of chain molecules is promoted to form specific carbon-carbon bonds and conjugated systems, and 2% hydrocarbon-1-alkyne-4-alkenylbenzene is precisely synthesized. This approach can effectively avoid the complexity caused by multi-step reactions, and has high atomic economy, which has great application potential in the field of organic synthesis.
First, it can be achieved by the coupling reaction of alkynes and halogenated aromatics. Select suitable active halogenated aromatics, such as brominated or iodobenzene derivatives, and react with alkynyl-containing compounds in a suitable solvent in the presence of palladium, copper and other metal catalysts and ligands. If a palladium catalyst is used, tetrakis (triphenylphosphine) palladium (0) is often selected, and copper salts can be selected from cuprous iodide. The ligand can be triethylamine, etc., in an organic solvent such as dichloromethane, N, N-dimethylformamide, stirred at a moderate temperature, and after metal-catalyzed oxidation addition, transmetallization and reduction elimination steps, the target 2-% hydrocarbon-1-alkynyl-4-alkenylbenzene can be generated.
Second, the strategy of alkenylation reaction is adopted. First, an alkenyl intermediate containing a specific substituent is prepared, and alkenyl borate or alkenyl halide is used as raw material to react with alkynylbenzene derivatives under basic conditions and metal catalysis. For example, under the catalysis of alkenyl borate and alkynyl benzene in bases such as potassium carbonate and tetrakis (triphenylphosphine) palladium (0), the reaction is heated in a dioxane-water mixed solvent, and the boron atom is metallized with the aryl group of alkynyl benzene, and then eliminated by oxidative addition and reduction to construct the required carbon-carbon bond to achieve the synthesis of 2-% hydrocarbon-1-alkynyl-4-alkenyl benzene.
Third, the cyclization reaction catalyzed by transition metals is used. Take an appropriate chain precursor, containing alkenyl, alkynyl and phenyl ring structural units, and under the action of a transition metal catalyst, an intramolecular cyclization reaction occurs. For example, using metal catalysts such as rhodium or ruthenium, under mild conditions, cyclization of chain molecules is promoted to form specific carbon-carbon bonds and conjugated systems, and 2% hydrocarbon-1-alkyne-4-alkenylbenzene is precisely synthesized. This approach can effectively avoid the complexity caused by multi-step reactions, and has high atomic economy, which has great application potential in the field of organic synthesis.
What are the precautions for using 2-bromo-1-chloro-4-fluorobenzene?
2-% -1-4-4-kudzu, use it, and observe all kinds of things, so that it can be used and effective.
The first heavy storage. It should be placed in a place where things are dry and dry, away from direct light and tides. If it is a place where the tide is, 2-% kudzu is easy to gather, 1-kudzu is easy to burn, and 4-kudzu is also easy to mildew and rot, losing its efficacy.
Use the same amount. According to the required amount, use it as appropriate. Amount, 2-% kudzu is diffuse, 1-kudzu is strong and pungent, 4-kudzu is too fierce, and it is afraid of being damaged; if the dosage is insufficient, it will be effective during the harvest period.
The method of operation is also good. Make 2-% Different needs, compatibility is good, compatibility is appropriate, and the efficacy complements each other; compatibility is lost, or effective, or even harmful. Therefore, use 2-% -1--4-4-Ge, and pay attention to it all, in order to make good use of it and avoid its drawbacks.
The first heavy storage. It should be placed in a place where things are dry and dry, away from direct light and tides. If it is a place where the tide is, 2-% kudzu is easy to gather, 1-kudzu is easy to burn, and 4-kudzu is also easy to mildew and rot, losing its efficacy.
Use the same amount. According to the required amount, use it as appropriate. Amount, 2-% kudzu is diffuse, 1-kudzu is strong and pungent, 4-kudzu is too fierce, and it is afraid of being damaged; if the dosage is insufficient, it will be effective during the harvest period.
The method of operation is also good. Make 2-% Different needs, compatibility is good, compatibility is appropriate, and the efficacy complements each other; compatibility is lost, or effective, or even harmful. Therefore, use 2-% -1--4-4-Ge, and pay attention to it all, in order to make good use of it and avoid its drawbacks.
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