Linshang Chemical
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2-Bromo-1-Chloro-4-Methoxybenzene
Linshang Chemical
|
HS Code |
532738 |
| Chemical Formula | C7H6BrClO |
| Molecular Weight | 221.48 |
| Appearance | Solid |
| Boiling Point | Approx. 246 - 248 °C |
| Melting Point | 46 - 48 °C |
| Density | N/A |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | N/A |
| Odor | Characteristic odor |
| Purity | Typically high purity for commercial products |
As an accredited 2-Bromo-1-Chloro-4-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 2 - bromo - 1 - chloro - 4 - methoxybenzene packaged in a sealed glass bottle. |
| Storage | 2 - bromo - 1 - chloro - 4 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from sources of heat and ignition. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, strong acids, and bases to prevent potential chemical reactions. Label the storage container clearly with the chemical's name and relevant hazard information. |
| Shipping | 2 - bromo - 1 - chloro - 4 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. It's transported under regulated conditions to prevent spills, with care due to its chemical nature, following all relevant safety and shipping regulations. |
Competitive 2-Bromo-1-Chloro-4-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Bromo-1-Chloro-4-Methoxybenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Bromo-1-Chloro-4-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-bromo-1-chloro-4-methoxybenzene?
2-% hydroxyl-1-aldehyde-4-methoxybenzene, this substance is an organic compound with specific chemical properties. Its properties are mostly solid or liquid at room temperature, and the color state may vary slightly due to purity and structure.
From the perspective of chemical activity, 2-% hydroxyl-1-aldehyde-4-methoxybenzene contains hydroxyl groups, aldehyde groups and methoxy groups. Hydroxyl groups are hydrophilic and can participate in many reactions, such as esterification reactions, which can form esters with acids under the action of catalysts; they can also undergo dehydration reactions to form ethers or olefins under specific conditions. Aldose groups are highly active and can be oxidized to carboxyl groups. Common oxidants such as potassium permanganate and oxygen can also cause this oxidation; they can also undergo reduction reactions to obtain alcohols. At the same time, aldehyde groups can undergo condensation reactions with active hydrogen-containing compounds, such as Schiff bases with amines.
Although methoxy groups are relatively stable, substitution reactions can occur under certain conditions, such as strongly acidic or strongly alkaline environments, and methyl groups in methoxy groups may be replaced by other groups. And because of its power supply, it can affect the electron cloud density of the benzene ring, making the electron cloud density of the benzene ring ortho and para-sites increase, and it is more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Substitution check points are mostly in the ortho and para-sites of hydroxyl groups or aldehyde groups. In addition, due to the interaction of various groups in the molecule, the chemical properties of 2-% hydroxyl-1-aldehyde-4-methoxybenzene are more complex. The specific conditions and products of each reaction depend on the actual reaction system and operation details.
From the perspective of chemical activity, 2-% hydroxyl-1-aldehyde-4-methoxybenzene contains hydroxyl groups, aldehyde groups and methoxy groups. Hydroxyl groups are hydrophilic and can participate in many reactions, such as esterification reactions, which can form esters with acids under the action of catalysts; they can also undergo dehydration reactions to form ethers or olefins under specific conditions. Aldose groups are highly active and can be oxidized to carboxyl groups. Common oxidants such as potassium permanganate and oxygen can also cause this oxidation; they can also undergo reduction reactions to obtain alcohols. At the same time, aldehyde groups can undergo condensation reactions with active hydrogen-containing compounds, such as Schiff bases with amines.
Although methoxy groups are relatively stable, substitution reactions can occur under certain conditions, such as strongly acidic or strongly alkaline environments, and methyl groups in methoxy groups may be replaced by other groups. And because of its power supply, it can affect the electron cloud density of the benzene ring, making the electron cloud density of the benzene ring ortho and para-sites increase, and it is more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Substitution check points are mostly in the ortho and para-sites of hydroxyl groups or aldehyde groups. In addition, due to the interaction of various groups in the molecule, the chemical properties of 2-% hydroxyl-1-aldehyde-4-methoxybenzene are more complex. The specific conditions and products of each reaction depend on the actual reaction system and operation details.
What are the physical properties of 2-bromo-1-chloro-4-methoxybenzene?
2-% hydroxyl-1-alkane-4-methoxybenzene is one of the organic compounds. Its physical properties are unique and related to many chemical and industrial applications.
Looking at its properties, under room temperature and pressure, 2-% hydroxyl-1-alkyl-4-methoxybenzene often appears in a solid state, or is a crystalline powder, with a fine texture. The color is pure, or nearly colorless, or slightly yellow, which varies slightly due to its purity and impurities.
When it comes to the melting point, it has been determined by many Fang family experiments that it is about a specific temperature range. This temperature is the key node of its transition from solid state to liquid state, and it is of great significance for its separation, purification and application in specific processes. When the ambient temperature rises near the melting point, the ordered structure of the lattice of the substance is gradually disturbed by thermal energy, and the intermolecular force weakens, thereby triggering a change in the state of matter.
The boiling point is also a specific value. The boiling point is the temperature at which a substance changes from liquid state to gas state under a specific pressure. The boiling point of 2% hydroxyl-1-alkane-4-methoxybenzene reflects the difficulty of gasification. In the distillation and fractionation operations of chemical production, this parameter is an important basis for separating this substance from other components.
In terms of solubility, in common organic solvents such as ethanol, ether, etc., 2% hydroxyl-1-alkyl-4-methoxybenzene exhibits certain solubility. Ethanol is a polar organic solvent. It can interact with the molecules of the substance through hydrogen bonds, van der Waals forces, etc., so that some of the molecules of the substance are uniformly dispersed in ethanol to form a uniform solution; although ether has a weak polarity, it also has a certain solubility to 2-% hydroxyl-1-alkane-4-methoxybenzene due to the principle of similar phase dissolution. However, in water, its solubility is relatively limited, because the polarity of water is strong, and the molecular structure of the organic compound is quite different, and the intermolecular interaction is difficult to promote its large-scale dissolution.
Density is also one of its important physical properties. The density of the substance indicates the mass of the substance contained in a unit volume, and is indispensable for storage, transportation, and in some process designs involving the relationship between volume and mass. Only by accurately knowing its density can we reasonably plan the size of the storage container and the carrying capacity of the transportation vehicle.
Looking at its properties, under room temperature and pressure, 2-% hydroxyl-1-alkyl-4-methoxybenzene often appears in a solid state, or is a crystalline powder, with a fine texture. The color is pure, or nearly colorless, or slightly yellow, which varies slightly due to its purity and impurities.
When it comes to the melting point, it has been determined by many Fang family experiments that it is about a specific temperature range. This temperature is the key node of its transition from solid state to liquid state, and it is of great significance for its separation, purification and application in specific processes. When the ambient temperature rises near the melting point, the ordered structure of the lattice of the substance is gradually disturbed by thermal energy, and the intermolecular force weakens, thereby triggering a change in the state of matter.
The boiling point is also a specific value. The boiling point is the temperature at which a substance changes from liquid state to gas state under a specific pressure. The boiling point of 2% hydroxyl-1-alkane-4-methoxybenzene reflects the difficulty of gasification. In the distillation and fractionation operations of chemical production, this parameter is an important basis for separating this substance from other components.
In terms of solubility, in common organic solvents such as ethanol, ether, etc., 2% hydroxyl-1-alkyl-4-methoxybenzene exhibits certain solubility. Ethanol is a polar organic solvent. It can interact with the molecules of the substance through hydrogen bonds, van der Waals forces, etc., so that some of the molecules of the substance are uniformly dispersed in ethanol to form a uniform solution; although ether has a weak polarity, it also has a certain solubility to 2-% hydroxyl-1-alkane-4-methoxybenzene due to the principle of similar phase dissolution. However, in water, its solubility is relatively limited, because the polarity of water is strong, and the molecular structure of the organic compound is quite different, and the intermolecular interaction is difficult to promote its large-scale dissolution.
Density is also one of its important physical properties. The density of the substance indicates the mass of the substance contained in a unit volume, and is indispensable for storage, transportation, and in some process designs involving the relationship between volume and mass. Only by accurately knowing its density can we reasonably plan the size of the storage container and the carrying capacity of the transportation vehicle.
What are the main uses of 2-bromo-1-chloro-4-methoxybenzene?
2-% hydroxyl-1-aldehyde-4-methoxybenzene, although this substance is not directly described in Tiangong Kaiji, its use can be deduced according to various chemical and medicinal methods.
In the field of medicine, it may be a key intermediate for the synthesis of many drugs. The combination of methoxy, aldehyde and hydroxyl groups endows it with unique chemical activity, which can be used by organic synthesis to cleverly react with other compounds to construct molecular structures with specific pharmacological activities. For example, when creating antibacterial and anti-inflammatory drugs, it can be used to introduce suitable functional groups to optimize the affinity and activity of the drug to specific targets, thereby enhancing the curative effect.
In the field of fragrance, it also has potential value. Aldol and hydroxyl groups can impart a special smell to substances. After formulation and modification, they may become important components in the formulation of new fragrances, adding a unique flavor to fragrance products, used in perfumes, cosmetics, etc., to create a different olfactory experience.
In the field of organic synthesis chemistry, 2-% hydroxyl-1-aldehyde-4-methoxybenzene can be used as a basic raw material to participate in the construction of complex organic compounds. With its multiple activity check points, it can build a multi-ring or chain structure through condensation, addition and other reactions, providing a starting structure for the synthesis of high value-added chemical products, such as special plastic additives, high-performance coating ingredients, etc., to promote the optimization and innovation of chemical material properties.
In the field of medicine, it may be a key intermediate for the synthesis of many drugs. The combination of methoxy, aldehyde and hydroxyl groups endows it with unique chemical activity, which can be used by organic synthesis to cleverly react with other compounds to construct molecular structures with specific pharmacological activities. For example, when creating antibacterial and anti-inflammatory drugs, it can be used to introduce suitable functional groups to optimize the affinity and activity of the drug to specific targets, thereby enhancing the curative effect.
In the field of fragrance, it also has potential value. Aldol and hydroxyl groups can impart a special smell to substances. After formulation and modification, they may become important components in the formulation of new fragrances, adding a unique flavor to fragrance products, used in perfumes, cosmetics, etc., to create a different olfactory experience.
In the field of organic synthesis chemistry, 2-% hydroxyl-1-aldehyde-4-methoxybenzene can be used as a basic raw material to participate in the construction of complex organic compounds. With its multiple activity check points, it can build a multi-ring or chain structure through condensation, addition and other reactions, providing a starting structure for the synthesis of high value-added chemical products, such as special plastic additives, high-performance coating ingredients, etc., to promote the optimization and innovation of chemical material properties.
What are the synthesis methods of 2-bromo-1-chloro-4-methoxybenzene?
To prepare 2-hydroxyl-1-aldehyde-4-methoxybenzene, there are various methods. First, it can be started from phenols, methoxylated, and then the aldehyde and hydroxyl groups are introduced. If p-cresol is used as the starting point, it is first encountered with reagents such as dimethyl sulfate, and methoxylated with the help of alkali to obtain p-methoxytoluene. Later, a mild oxidation method, such as manganese dioxide and sulfuric acid, can be used to oxidize the methyl group to an aldehyde group, and then by suitable hydroxylation means, such as peroxides or special catalysts, the hydroxyl group is introduced into the designated position.
Second, it is derived from benzaldehyde derivatives. First, benzaldehyde is introduced into methoxy group with suitable reagents, such as iodomethane and alkali, to obtain methoxybenzaldehyde. Then a specific organometallic reagent, such as Grignard reagent, interacts with the corresponding carbonyl compound, and through hydrolysis and other steps, the hydroxyl group and aldehyde group are introduced. Under appropriate reaction conditions, it can reach 2-hydroxyl-1-aldehyde-4-methoxybenzene.
Third, the electrophilic substitution reaction of aromatic rings is used. Using benzene as the group, the methoxy group is first introduced, which can be catalyzed by halogenated methane and metal salts. Through Foucault acylation reaction, the acyl group containing aldehyde group and hydroxyl precursor is introduced, and then converted into the target product through reduction, hydrolysis and other series. These methods have their own advantages and disadvantages, and they need to be carefully selected according to the actual raw materials, equipment and cost factors.
Second, it is derived from benzaldehyde derivatives. First, benzaldehyde is introduced into methoxy group with suitable reagents, such as iodomethane and alkali, to obtain methoxybenzaldehyde. Then a specific organometallic reagent, such as Grignard reagent, interacts with the corresponding carbonyl compound, and through hydrolysis and other steps, the hydroxyl group and aldehyde group are introduced. Under appropriate reaction conditions, it can reach 2-hydroxyl-1-aldehyde-4-methoxybenzene.
Third, the electrophilic substitution reaction of aromatic rings is used. Using benzene as the group, the methoxy group is first introduced, which can be catalyzed by halogenated methane and metal salts. Through Foucault acylation reaction, the acyl group containing aldehyde group and hydroxyl precursor is introduced, and then converted into the target product through reduction, hydrolysis and other series. These methods have their own advantages and disadvantages, and they need to be carefully selected according to the actual raw materials, equipment and cost factors.
What should I pay attention to when storing and transporting 2-bromo-1-chloro-4-methoxybenzene?
When hiding and transporting 2-% hydroxyl-1-alkane-4-methoxyphenyl, pay attention to all kinds of matters.
When hiding, the first environment is heavy. The place must be cool and dry, protected from direct sunlight. Cover it with sunlight, or cause its properties to change, and its medicinal power may be lost. Also avoid moisture and moisture invading it, and it is prone to the risk of mildew and rot, which will damage its quality.
Next time, pay attention to the temperature. It is not suitable to be in a place with high temperature. Under high temperature, it may cause chemical reactions and cause changes in its ingredients. It should also not be placed in an extremely cold place. Sudden cold and sudden heat are harmful to its quality.
Furthermore, the storage place should be clean, away from filth and sundries, and prevent it from mixing with other things, causing the ingredients to be mixed and lose their original effect.
When shipping, the packaging must be solid. Choose the right packaging material to prevent it from being damaged by shock and pressure during transportation. The packaging must be well sealed to prevent it from coming into contact with outside air and moisture.
The transportation tools must also be clean, dry and well ventilated. Do not transport with odorous things or rotten things, so as not to stain them with odor or change their quality due to damage from other things.
The temperature should be controlled during the journey, and the temperature range should be selected according to its nature to ensure its stable quality. Escorts should also be cautious, check its condition frequently, and if there is any abnormality, dispose of it immediately to ensure that the 2-% hydroxyl-1-alkane-4-methoxybenzene is stored and transported without losing its characteristics.
When hiding, the first environment is heavy. The place must be cool and dry, protected from direct sunlight. Cover it with sunlight, or cause its properties to change, and its medicinal power may be lost. Also avoid moisture and moisture invading it, and it is prone to the risk of mildew and rot, which will damage its quality.
Next time, pay attention to the temperature. It is not suitable to be in a place with high temperature. Under high temperature, it may cause chemical reactions and cause changes in its ingredients. It should also not be placed in an extremely cold place. Sudden cold and sudden heat are harmful to its quality.
Furthermore, the storage place should be clean, away from filth and sundries, and prevent it from mixing with other things, causing the ingredients to be mixed and lose their original effect.
When shipping, the packaging must be solid. Choose the right packaging material to prevent it from being damaged by shock and pressure during transportation. The packaging must be well sealed to prevent it from coming into contact with outside air and moisture.
The transportation tools must also be clean, dry and well ventilated. Do not transport with odorous things or rotten things, so as not to stain them with odor or change their quality due to damage from other things.
The temperature should be controlled during the journey, and the temperature range should be selected according to its nature to ensure its stable quality. Escorts should also be cautious, check its condition frequently, and if there is any abnormality, dispose of it immediately to ensure that the 2-% hydroxyl-1-alkane-4-methoxybenzene is stored and transported without losing its characteristics.
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