Linshang Chemical
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2-Bromo-3-Chloronitrobenzene
Linshang Chemical
|
HS Code |
177459 |
| Name | 2-Bromo-3-Chloronitrobenzene |
| Molecular Formula | C6H3BrClNO2 |
| Molecular Weight | 236.45 |
| Appearance | Yellow solid |
| Melting Point | 54 - 58 °C |
| Boiling Point | 274.5 °C at 760 mmHg |
| Density | 1.805 g/cm³ |
| Solubility In Water | Insoluble |
| Flash Point | 119.8 °C |
| Refractive Index | 1.626 |
As an accredited 2-Bromo-3-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 - gram bottle packaging for 2 - bromo - 3 - chloronitrobenzene chemical. |
| Storage | 2 - bromo - 3 - chloronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other reactive substances to avoid potential chemical reactions. Use appropriate storage cabinets dedicated to hazardous chemicals. |
| Shipping | 2 - bromo - 3 - chloronitrobenzene is shipped in sealed, corrosion - resistant containers. It's carefully packaged to prevent leakage. Shipment follows strict regulations for hazardous chemicals, ensuring safety during transit. |
Competitive 2-Bromo-3-Chloronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Bromo-3-Chloronitrobenzene in China?
As a trusted 2-Bromo-3-Chloronitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Bromo-3-Chloronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-bromo-3-chloronitrobenzene?
2-% arsine-3-mercaptopyridine has important uses in many fields.
In the field of medicinal chemistry, it can be used as a key pharmaceutical intermediate. With its unique chemical structure, it can participate in the construction process of many drug molecules. For example, in the synthesis of some antibacterial and antiviral drugs, 2-% arsine-3-mercaptopyridine can be used as a starting material or a key reaction intermediate. With the help of a series of chemical reactions, the structure of the target drug molecule is gradually built and improved, and new drugs with more significant efficacy can be developed.
In the field of materials science, this compound also shows unique value. It can be used to prepare materials with special properties, such as some adsorption materials with high selective adsorption capacity for specific substances. The arsine group and sulfhydryl group in its structure can interact specifically with specific metal ions or organic molecules, so that the prepared materials play an important role in separating and enriching specific substances.
In the field of organic synthetic chemistry, 2-% arsine-3-mercaptopyridine, as a class of reagents with special activities, can participate in a variety of organic reactions. For example, when building a complex organic molecular skeleton, it can react with other organic reagents through nucleophilic substitution and addition, providing organic synthetic chemists with more strategies and paths to construct new organic compounds, and promoting the sustainable development of organic synthetic chemistry.
In the field of medicinal chemistry, it can be used as a key pharmaceutical intermediate. With its unique chemical structure, it can participate in the construction process of many drug molecules. For example, in the synthesis of some antibacterial and antiviral drugs, 2-% arsine-3-mercaptopyridine can be used as a starting material or a key reaction intermediate. With the help of a series of chemical reactions, the structure of the target drug molecule is gradually built and improved, and new drugs with more significant efficacy can be developed.
In the field of materials science, this compound also shows unique value. It can be used to prepare materials with special properties, such as some adsorption materials with high selective adsorption capacity for specific substances. The arsine group and sulfhydryl group in its structure can interact specifically with specific metal ions or organic molecules, so that the prepared materials play an important role in separating and enriching specific substances.
In the field of organic synthetic chemistry, 2-% arsine-3-mercaptopyridine, as a class of reagents with special activities, can participate in a variety of organic reactions. For example, when building a complex organic molecular skeleton, it can react with other organic reagents through nucleophilic substitution and addition, providing organic synthetic chemists with more strategies and paths to construct new organic compounds, and promoting the sustainable development of organic synthetic chemistry.
What are the physical properties of 2-bromo-3-chloronitrobenzene?
2-% cyanogen-3-fluorobenzylbenzene, which is an organic compound. Its physical properties are as follows:
Under normal temperature and pressure, it is mostly colorless to light yellow liquid, but it may also be mixed with some impurities, resulting in a slight deviation in color. The appearance of this liquid is clear, and occasionally it has a special weak smell, but the smell is quite subtle and is not easily detectable by ordinary people.
When it comes to the boiling point, it has been determined by many experiments that its boiling point is about a specific temperature range. Due to the difference in experimental environment and instrument accuracy, it hovers roughly between [X] ° C - [X] ° C. In this temperature range, 2% cyanogen-3-fluorobenzylbenzene will gradually change from liquid to gaseous state, which is an important physical transformation property.
In terms of melting point, when the temperature drops to a specific value, the substance will condense from liquid to solid state. Its melting point is about [X] ° C. At this temperature, intermolecular forces promote a more orderly arrangement of molecules, thus realizing the transformation of the state of matter.
As for solubility, 2% cyanogen-3-fluorobenzylbenzylbenzene exhibits good solubility in organic solvents. Organic solvents such as common ether and dichloromethane can be miscible with it. However, in water, its solubility is extremely poor. Due to the characteristics of its molecular structure, it is difficult to form an effective interaction with water molecules, so it is almost insoluble in water.
In addition, its density is also a key physical property. Under standard conditions, the density of 2-% cyanogen-3-fluorobenzylbenzene is about [X] g/cm ³, which may be different from the density of water. This property is of important significance in many chemical operations and applications.
Under normal temperature and pressure, it is mostly colorless to light yellow liquid, but it may also be mixed with some impurities, resulting in a slight deviation in color. The appearance of this liquid is clear, and occasionally it has a special weak smell, but the smell is quite subtle and is not easily detectable by ordinary people.
When it comes to the boiling point, it has been determined by many experiments that its boiling point is about a specific temperature range. Due to the difference in experimental environment and instrument accuracy, it hovers roughly between [X] ° C - [X] ° C. In this temperature range, 2% cyanogen-3-fluorobenzylbenzene will gradually change from liquid to gaseous state, which is an important physical transformation property.
In terms of melting point, when the temperature drops to a specific value, the substance will condense from liquid to solid state. Its melting point is about [X] ° C. At this temperature, intermolecular forces promote a more orderly arrangement of molecules, thus realizing the transformation of the state of matter.
As for solubility, 2% cyanogen-3-fluorobenzylbenzylbenzene exhibits good solubility in organic solvents. Organic solvents such as common ether and dichloromethane can be miscible with it. However, in water, its solubility is extremely poor. Due to the characteristics of its molecular structure, it is difficult to form an effective interaction with water molecules, so it is almost insoluble in water.
In addition, its density is also a key physical property. Under standard conditions, the density of 2-% cyanogen-3-fluorobenzylbenzene is about [X] g/cm ³, which may be different from the density of water. This property is of important significance in many chemical operations and applications.
What are the chemical properties of 2-bromo-3-chloronitrobenzene?
The chemical properties of 2-% cyanogen-3-fluorobenzyl benzene can be studied. This substance contains cyanogen and fluorobenzyl, and the cyanyl group has high reactivity and shows remarkable characteristics in many chemical reactions. It has nucleophilic properties and can react with electrophilic reagents to form new chemical bonds. And the carbon-nitrogen triple bond in the cyanyl group is rich in electrons, making it easy to participate in addition reactions. For example, with compounds containing carbonyl groups, it can be nucleophilic addition, and various derivatives are widely used in organic synthesis.
Furthermore, the fluorine atom of the 3-fluorobenzyl group has strong electronegativity, which has a great impact on the distribution of molecular electron clouds. Due to its electron-absorbing effect, the electron cloud density on benzyl carbons decreases, which affects the reactivity of the atoms or groups connected to them. This structure makes the compound in the nucleophilic substitution reaction, the reactivity of the benzyl position may change, or it is more susceptible to nucleophilic attack, or it varies according to the reaction conditions and substrate characteristics.
From a holistic perspective, the chemical properties of 2-cyano- 3-fluorobenzylbenzylbenzene are influenced by the interaction of cyano- and fluorobenzyl groups. The electronic effects and spatial effects of the two are intertwined, so that the compound exhibits unique reaction paths and products under different reaction environments. In the field of organic synthesis, using its special chemical properties, novel synthesis strategies can be designed to produce organic molecules with specific structures and functions, providing important raw materials and ideas for the creation of new drugs and the development of new materials. It has potential applications and in-depth exploration value in catalytic reactions, organometallic chemistry, etc., or due to its unique chemical properties.
Furthermore, the fluorine atom of the 3-fluorobenzyl group has strong electronegativity, which has a great impact on the distribution of molecular electron clouds. Due to its electron-absorbing effect, the electron cloud density on benzyl carbons decreases, which affects the reactivity of the atoms or groups connected to them. This structure makes the compound in the nucleophilic substitution reaction, the reactivity of the benzyl position may change, or it is more susceptible to nucleophilic attack, or it varies according to the reaction conditions and substrate characteristics.
From a holistic perspective, the chemical properties of 2-cyano- 3-fluorobenzylbenzylbenzene are influenced by the interaction of cyano- and fluorobenzyl groups. The electronic effects and spatial effects of the two are intertwined, so that the compound exhibits unique reaction paths and products under different reaction environments. In the field of organic synthesis, using its special chemical properties, novel synthesis strategies can be designed to produce organic molecules with specific structures and functions, providing important raw materials and ideas for the creation of new drugs and the development of new materials. It has potential applications and in-depth exploration value in catalytic reactions, organometallic chemistry, etc., or due to its unique chemical properties.
What are the synthesis methods of 2-bromo-3-chloronitrobenzene?
The synthesis of 2-% cyanogen-3-fluorobenzyl nitrile is a very important topic in the field of organic synthesis. The following are common synthesis routes:
First, halobenzyl is used as the starting material. Halobenzyl and cyanide reagents, such as sodium cyanide and potassium cyanide, can be used in a suitable organic solvent, such as N, N-dimethylformamide (DMF), under the catalysis of a base, nucleophilic substitution occurs to generate benzylnitrile derivatives. Then, fluorine atoms are introduced at specific positions of benzylnitrile by means of selective fluorination. For example, using nucleophilic fluorination reagents, under specific reaction conditions, 2-cyanogen-3-fluorobenzylnitrile is achieved at the 2-position or 3-position fluorination, and then 2-cyanogen-3-fluorobenzylnitrile is obtained. The key to this path lies in the control of the conditions of the nucleophilic substitution and fluorination reaction to ensure the selectivity and yield of the reaction.
Second, by means of the functionalization reaction of the benzene ring. The benzene ring can be cyanylated first, for example, by using reagents such as trifluoromethanesulfonic anhydride and cuprous cyanide, and a cyanide group is introduced into the benzene ring in a suitable reaction system. Subsequently, the resulting product is halogenated to introduce a halogen atom, The structure of 2-cyanogen-3-fluorobenzyl nitrile was gradually constructed by multi-step reaction. This process requires fine planning of the reaction sequence to avoid unnecessary side reactions and improve the purity of the target product.
Third, benzyl alcohol derivatives are used as starting materials. First, benzyl alcohol is converted into the corresponding halogenate, and then reacted with cyanide reagents to generate benzyl nitrile. Benzyl nitrile is then modified by fluorination. The advantage of this method is that benzyl alcohol compounds are widely sourced and easy to obtain. However, attention should be paid to the optimization of the reaction conditions at each step to ensure the efficient progress of each step. In conclusion, the synthesis of 2-cyanogen-3-fluorobenzylnitrile requires careful selection of the appropriate synthesis path based on the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the target product, and the precise optimization of the reaction conditions at each step to achieve the goal of efficient and high-purity synthesis.
First, halobenzyl is used as the starting material. Halobenzyl and cyanide reagents, such as sodium cyanide and potassium cyanide, can be used in a suitable organic solvent, such as N, N-dimethylformamide (DMF), under the catalysis of a base, nucleophilic substitution occurs to generate benzylnitrile derivatives. Then, fluorine atoms are introduced at specific positions of benzylnitrile by means of selective fluorination. For example, using nucleophilic fluorination reagents, under specific reaction conditions, 2-cyanogen-3-fluorobenzylnitrile is achieved at the 2-position or 3-position fluorination, and then 2-cyanogen-3-fluorobenzylnitrile is obtained. The key to this path lies in the control of the conditions of the nucleophilic substitution and fluorination reaction to ensure the selectivity and yield of the reaction.
Second, by means of the functionalization reaction of the benzene ring. The benzene ring can be cyanylated first, for example, by using reagents such as trifluoromethanesulfonic anhydride and cuprous cyanide, and a cyanide group is introduced into the benzene ring in a suitable reaction system. Subsequently, the resulting product is halogenated to introduce a halogen atom, The structure of 2-cyanogen-3-fluorobenzyl nitrile was gradually constructed by multi-step reaction. This process requires fine planning of the reaction sequence to avoid unnecessary side reactions and improve the purity of the target product.
Third, benzyl alcohol derivatives are used as starting materials. First, benzyl alcohol is converted into the corresponding halogenate, and then reacted with cyanide reagents to generate benzyl nitrile. Benzyl nitrile is then modified by fluorination. The advantage of this method is that benzyl alcohol compounds are widely sourced and easy to obtain. However, attention should be paid to the optimization of the reaction conditions at each step to ensure the efficient progress of each step. In conclusion, the synthesis of 2-cyanogen-3-fluorobenzylnitrile requires careful selection of the appropriate synthesis path based on the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the target product, and the precise optimization of the reaction conditions at each step to achieve the goal of efficient and high-purity synthesis.
What are the precautions for storing and transporting 2-bromo-3-chloronitrobenzene?
For 2-% hydroxyl-3-aminopyridine, there are all kinds of things to pay attention to when hiding and transporting it.
When hiding, the first environment is heavy. It should be placed in a cool and dry place, away from direct sunlight. Cover the heat and light of sunlight, or cause changes in its properties, affecting its quality. And it must be kept away from fire and heat sources, which can cause the risk of combustion, because of its chemical or flammable properties. And it should be stored separately from oxidants, acids, etc., to avoid the risk of chemical reactions. If the two are mixed, or react violently, cause material deterioration, and even cause dangerous accidents.
When transporting, it should not be ignored. Be sure that the packaging is complete and the loading is secure. If the package is damaged, the material may leak out, damaging its quality and endangering the surroundings. The loading is unstable, and it is easy to cause collision and dumping during transportation, which increases the possibility of package damage. When transporting, it is also necessary to choose suitable tools. It is advisable to use well-ventilated and fire-proof transportation equipment to deal with the situation during transportation. Transport personnel should also be aware of the characteristics and emergency measures of this object. In case of an emergency, they can quickly and properly dispose of it to reduce the damage.
All these kinds of things need to be treated with caution in order to ensure the safety of 2-hydroxy- 3-aminopyridine during transportation, so that its quality is not damaged and it is used properly.
When hiding, the first environment is heavy. It should be placed in a cool and dry place, away from direct sunlight. Cover the heat and light of sunlight, or cause changes in its properties, affecting its quality. And it must be kept away from fire and heat sources, which can cause the risk of combustion, because of its chemical or flammable properties. And it should be stored separately from oxidants, acids, etc., to avoid the risk of chemical reactions. If the two are mixed, or react violently, cause material deterioration, and even cause dangerous accidents.
When transporting, it should not be ignored. Be sure that the packaging is complete and the loading is secure. If the package is damaged, the material may leak out, damaging its quality and endangering the surroundings. The loading is unstable, and it is easy to cause collision and dumping during transportation, which increases the possibility of package damage. When transporting, it is also necessary to choose suitable tools. It is advisable to use well-ventilated and fire-proof transportation equipment to deal with the situation during transportation. Transport personnel should also be aware of the characteristics and emergency measures of this object. In case of an emergency, they can quickly and properly dispose of it to reduce the damage.
All these kinds of things need to be treated with caution in order to ensure the safety of 2-hydroxy- 3-aminopyridine during transportation, so that its quality is not damaged and it is used properly.
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