Linshang Chemical
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2-Bromo-4,5-Dichloronitrobenzene
Linshang Chemical
|
HS Code |
633064 |
| Chemical Formula | C6H2BrCl2NO2 |
| Molecular Weight | 272.89 |
| Appearance | Solid (Typically a yellow - to - off - white solid) |
| Physical State At Room Temperature | Solid |
| Melting Point | Specific value would need experimental determination, but generally in a certain range for such aromatic compounds |
| Boiling Point | Estimated to be relatively high due to its molecular structure and intermolecular forces |
| Solubility In Water | Low (due to its non - polar nature and presence of hydrophobic groups) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, etc. |
| Density | Data requires experimental measurement, but can be estimated based on related compounds |
| Odor | May have a characteristic, somewhat pungent odor associated with halogen - and nitro - containing aromatic compounds |
| Stability | Stable under normal conditions, but may react with strong reducing agents, bases, etc. |
As an accredited 2-Bromo-4,5-Dichloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 2 - bromo - 4,5 - dichloronitrobenzene in a sealed, labeled chemical bottle. |
| Storage | 2 - bromo - 4,5 - dichloronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It is a hazardous chemical, so store it in a dedicated chemical storage cabinet or area. Keep it separate from incompatible substances like oxidizing agents, reducing agents, and bases to prevent potential reactions. Ensure proper labeling for easy identification and safety. |
| Shipping | 2 - bromo - 4,5 - dichloronitrobenzene is a chemical. Ship it in well - sealed containers, following regulations for hazardous chemicals. Ensure proper labeling, and transport with carriers experienced in handling such substances to prevent spills and ensure safety. |
Competitive 2-Bromo-4,5-Dichloronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Bromo-4,5-Dichloronitrobenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Bromo-4,5-Dichloronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-bromo-4,5-dichloronitrobenzene?
2-% hydroxyl-4,5-difluorobenzyl ether is an organic compound widely used in the chemical and pharmaceutical fields. Its main uses are as follows:
Key intermediates in pharmaceutical synthesis
In the field of pharmaceutical chemistry, 2-% hydroxyl-4,5-difluorobenzyl ether is often used as an important intermediate for the synthesis of a variety of biologically active compounds. Due to the unique electronic and spatial effects of fluorine atoms, fluorinated organic compounds often perform well in drug molecules. For example, in the development of antimicrobial drugs, by introducing structural units containing 2-% hydroxyl-4,5-difluorobenzyl ether, the permeability of the drug to the bacterial cell wall or cell membrane can be improved, and its binding force with specific bacterial targets can be enhanced, thereby enhancing antibacterial activity and selectivity, providing the possibility for the development of high-efficiency and low-toxicity antibacterial drugs. For example, in the development of anti-tumor drugs, the compound structural unit can optimize the lipophilicity and electron cloud distribution of drug molecules, enhance the affinity and targeting of drugs to tumor cells, and help improve the anti-tumor efficacy and reduce the toxic side effects on normal cells.
Pesticide Creation Important Raw Materials
In the field of pesticides, 2-% hydroxyl-4,5-difluorobenzyl ether is also an important raw material. Modern pesticide research and development pursues high-efficiency, low-toxicity and environmentally friendly varieties. Fluorinated pesticides often have high-efficiency insecticidal, bactericidal or herbicidal activities due to the characteristics of fluorine atoms. Using them as raw materials to synthesize pesticides can enhance the molecular stability and biological activity of pesticides. For example, when synthesizing new insecticides, pesticides containing this structure can more effectively interfere with the nervous system or physiological metabolic processes of insects, improve insecticidal efficiency, and at the same time delay the generation of pest resistance and prolong the service life of pesticides due to their unique mechanism of action.
Widely used in the field of fine chemicals
In the field of fine chemicals, 2-% hydroxyl-4,5-difluorobenzyl ether is used to synthesize special functional materials and fine chemicals. For example, in the synthesis of some high-performance coatings and plastic additives, the introduction of this structure can improve material properties. In coatings, it can enhance the weather resistance, chemical corrosion resistance and wear resistance of coatings; in plastic additives, it can improve the thermal stability, oxidation resistance and processing performance of plastic products. In addition, in the field of fragrance and flavor synthesis, it may be used as a special structural fragment to endow products with unique aroma and stability, expanding the variety and application range of fragrances.
Key intermediates in pharmaceutical synthesis
In the field of pharmaceutical chemistry, 2-% hydroxyl-4,5-difluorobenzyl ether is often used as an important intermediate for the synthesis of a variety of biologically active compounds. Due to the unique electronic and spatial effects of fluorine atoms, fluorinated organic compounds often perform well in drug molecules. For example, in the development of antimicrobial drugs, by introducing structural units containing 2-% hydroxyl-4,5-difluorobenzyl ether, the permeability of the drug to the bacterial cell wall or cell membrane can be improved, and its binding force with specific bacterial targets can be enhanced, thereby enhancing antibacterial activity and selectivity, providing the possibility for the development of high-efficiency and low-toxicity antibacterial drugs. For example, in the development of anti-tumor drugs, the compound structural unit can optimize the lipophilicity and electron cloud distribution of drug molecules, enhance the affinity and targeting of drugs to tumor cells, and help improve the anti-tumor efficacy and reduce the toxic side effects on normal cells.
Pesticide Creation Important Raw Materials
In the field of pesticides, 2-% hydroxyl-4,5-difluorobenzyl ether is also an important raw material. Modern pesticide research and development pursues high-efficiency, low-toxicity and environmentally friendly varieties. Fluorinated pesticides often have high-efficiency insecticidal, bactericidal or herbicidal activities due to the characteristics of fluorine atoms. Using them as raw materials to synthesize pesticides can enhance the molecular stability and biological activity of pesticides. For example, when synthesizing new insecticides, pesticides containing this structure can more effectively interfere with the nervous system or physiological metabolic processes of insects, improve insecticidal efficiency, and at the same time delay the generation of pest resistance and prolong the service life of pesticides due to their unique mechanism of action.
Widely used in the field of fine chemicals
In the field of fine chemicals, 2-% hydroxyl-4,5-difluorobenzyl ether is used to synthesize special functional materials and fine chemicals. For example, in the synthesis of some high-performance coatings and plastic additives, the introduction of this structure can improve material properties. In coatings, it can enhance the weather resistance, chemical corrosion resistance and wear resistance of coatings; in plastic additives, it can improve the thermal stability, oxidation resistance and processing performance of plastic products. In addition, in the field of fragrance and flavor synthesis, it may be used as a special structural fragment to endow products with unique aroma and stability, expanding the variety and application range of fragrances.
What are the synthesis methods of 2-bromo-4,5-dichloronitrobenzene?
There are many synthesis methods of 2-% cyanogen-4,5-difluorobenzoyl benzene, which are described in detail below.
One is the cyanidation of halogenated aromatic hydrocarbons. This is a halogenated aromatic hydrocarbon as a starting material. Under the action of cyanide reagents, cyanide is reacted to obtain a cyanide-containing intermediate, and then reacts with fluorobenzoyl-containing related reagents to synthesize the target product. For example, select an appropriate halogenated benzene, and in a cyanide reagent such as cuprous cyanide and a specific catalyst and solvent system, heat the reaction to replace the halogen atom with a cyanide group to form a cyanobenzene derivative. Subsequent reactions such as fluorination and condensation with benzoyl groups are carried out, and the reaction conditions, such as temperature, reaction time, and the proportion of reactants, are carefully adjusted to obtain the product efficiently.
The second is the benzoic acid derivative method. Using benzoic acid or its derivatives as the starting material, the fluorination reaction is carried out first, and fluorine atoms are introduced to construct fluorobenzoic acid derivatives. Then, through the acylation reaction, it is connected with a suitable benzene ring compound to construct the basic skeleton of the target product. In this process, the nucleophilic fluorination reagent can be selected for the fluorination step, and under suitable reaction conditions, precise fluorination can be achieved. The acylation reaction needs to select suitable acylating reagents and catalysts according to the characteristics of the reactants, and optimize the reaction parameters to improve the yield and purity of the product.
The third is the benzene ring construction method. The benzene ring structure is constructed through a multi-step reaction, and functional groups such as cyano, fluorine atoms and benzoyl groups are gradually introduced. This method often involves multi-step organic synthesis reactions, and the selectivity and yield of each step need to be precisely controlled. For example, a specific organic synthesis reaction is used to construct the benzene ring, and then cyano, fluorine atoms and benzoyl groups are introduced in sequence. After each step of the reaction, detailed separation and purification are required to ensure that the reaction proceeds in the desired direction, and finally 2% cyanide-4,5-difluorobenzoyl benzene is successfully synthesized.
The above methods have their own advantages and disadvantages. In actual synthesis, factors such as raw material availability, cost, reaction conditions and product purity requirements should be comprehensively considered, and appropriate synthesis paths should be carefully selected to efficiently and economically synthesize the target product.
One is the cyanidation of halogenated aromatic hydrocarbons. This is a halogenated aromatic hydrocarbon as a starting material. Under the action of cyanide reagents, cyanide is reacted to obtain a cyanide-containing intermediate, and then reacts with fluorobenzoyl-containing related reagents to synthesize the target product. For example, select an appropriate halogenated benzene, and in a cyanide reagent such as cuprous cyanide and a specific catalyst and solvent system, heat the reaction to replace the halogen atom with a cyanide group to form a cyanobenzene derivative. Subsequent reactions such as fluorination and condensation with benzoyl groups are carried out, and the reaction conditions, such as temperature, reaction time, and the proportion of reactants, are carefully adjusted to obtain the product efficiently.
The second is the benzoic acid derivative method. Using benzoic acid or its derivatives as the starting material, the fluorination reaction is carried out first, and fluorine atoms are introduced to construct fluorobenzoic acid derivatives. Then, through the acylation reaction, it is connected with a suitable benzene ring compound to construct the basic skeleton of the target product. In this process, the nucleophilic fluorination reagent can be selected for the fluorination step, and under suitable reaction conditions, precise fluorination can be achieved. The acylation reaction needs to select suitable acylating reagents and catalysts according to the characteristics of the reactants, and optimize the reaction parameters to improve the yield and purity of the product.
The third is the benzene ring construction method. The benzene ring structure is constructed through a multi-step reaction, and functional groups such as cyano, fluorine atoms and benzoyl groups are gradually introduced. This method often involves multi-step organic synthesis reactions, and the selectivity and yield of each step need to be precisely controlled. For example, a specific organic synthesis reaction is used to construct the benzene ring, and then cyano, fluorine atoms and benzoyl groups are introduced in sequence. After each step of the reaction, detailed separation and purification are required to ensure that the reaction proceeds in the desired direction, and finally 2% cyanide-4,5-difluorobenzoyl benzene is successfully synthesized.
The above methods have their own advantages and disadvantages. In actual synthesis, factors such as raw material availability, cost, reaction conditions and product purity requirements should be comprehensively considered, and appropriate synthesis paths should be carefully selected to efficiently and economically synthesize the target product.
What are the physical properties of 2-bromo-4,5-dichloronitrobenzene?
2-% cyanogen-4,5-difluorobenzoyl benzene, this is an organic compound with unique physical properties. Its properties are usually solid, due to the special molecular structure and intermolecular forces, it is solid at room temperature and has good stability.
Looking at its appearance, it is mostly white or off-white crystalline powder, with pure color and fine and uniform particles. This form is easy to store and transport, and is also conducive to subsequent use in various chemical reactions.
When it comes to melting point, it has been experimentally determined to be in a specific temperature range. The melting point characteristic is of great significance in the identification and purification of this compound. Its purity can be judged by melting point measurement. If there are few impurities, the melting point is close to the theoretical value and the melting range is narrow; if there are many impurities, the melting point will be reduced and the melting range will be widened.
In terms of solubility, it exhibits a certain solubility in organic solvents, such as common organic solvents acetonitrile and dichloromethane, which facilitates its application in organic synthesis reactions and enables the reaction to proceed efficiently in a homogeneous system. However, the solubility in water is very small. Due to the large difference between molecular polarity and water molecular polarity, it is not easily soluble in water according to the principle of similar miscibility.
In addition, the compound has a moderate density. Although the exact value needs to be determined by professional instruments, the specific density value can be used as a reference in the separation and identification of substances, and plays a role in some separation operations using density differences.
The physical properties of 2-% cyanogen-4,5-difluorobenzoyl benzene are of great significance in the fields of organic synthesis and materials science, laying the foundation for its application.
Looking at its appearance, it is mostly white or off-white crystalline powder, with pure color and fine and uniform particles. This form is easy to store and transport, and is also conducive to subsequent use in various chemical reactions.
When it comes to melting point, it has been experimentally determined to be in a specific temperature range. The melting point characteristic is of great significance in the identification and purification of this compound. Its purity can be judged by melting point measurement. If there are few impurities, the melting point is close to the theoretical value and the melting range is narrow; if there are many impurities, the melting point will be reduced and the melting range will be widened.
In terms of solubility, it exhibits a certain solubility in organic solvents, such as common organic solvents acetonitrile and dichloromethane, which facilitates its application in organic synthesis reactions and enables the reaction to proceed efficiently in a homogeneous system. However, the solubility in water is very small. Due to the large difference between molecular polarity and water molecular polarity, it is not easily soluble in water according to the principle of similar miscibility.
In addition, the compound has a moderate density. Although the exact value needs to be determined by professional instruments, the specific density value can be used as a reference in the separation and identification of substances, and plays a role in some separation operations using density differences.
The physical properties of 2-% cyanogen-4,5-difluorobenzoyl benzene are of great significance in the fields of organic synthesis and materials science, laying the foundation for its application.
What are the chemical properties of 2-bromo-4,5-dichloronitrobenzene?
2-% hydroxyl-4,5-difluorobenzylbenzene, this substance has many chemical properties. Its appearance is often colorless to light yellow liquid or solid, and the smell is unique. However, it is difficult to describe it in detail in words accurately, so it needs to be felt by yourself.
In terms of solubility, it performs well in organic solvents, such as common ethanol, ether, dichloromethane, etc., which can be well miscible. This property is due to the combination of molecular structure and the force between organic solvent molecules, which is convenient to act as a reactant or intermediate in organic synthesis reactions, so that the reaction can be carried out efficiently in homogeneous systems.
In terms of stability, it is relatively stable in conventional environments. However, when encountering strong acids, bases or strong oxidants, the chemical properties become active. In case of strong acids, some chemical bonds in the molecule are attacked by protons, triggering structural rearrangement or functional group transformation; in case of strong bases, hydroxyl groups may participate in acid-base neutralization or nucleophilic substitution reactions; in case of strong oxidants, such as potassium permanganate, etc., the easily oxidized parts of the molecule, such as benzyl positions, may be oxidized to higher valence functional groups such as carboxyl groups.
When it comes to reactivity, the reactivity is highlighted due to the presence of functional groups such as fluorine atoms and hydroxyl groups. Fluorine atoms have high electronegativity, which reduces the electron cloud density of carbon atoms connected to them, which is conducive to the attack of nucleophilic reagents and thus participates in nucleophilic substitution reactions; hydroxyl groups, as active functional groups, can undergo esterification reactions, generate esters with carboxylic acids or acyl chlorides under the action of catalysts, and These reactive activities provide various possibilities for organic synthetic chemists to construct complex organic molecular structures, and have important application value in medicinal chemistry, materials science and other fields.
In terms of solubility, it performs well in organic solvents, such as common ethanol, ether, dichloromethane, etc., which can be well miscible. This property is due to the combination of molecular structure and the force between organic solvent molecules, which is convenient to act as a reactant or intermediate in organic synthesis reactions, so that the reaction can be carried out efficiently in homogeneous systems.
In terms of stability, it is relatively stable in conventional environments. However, when encountering strong acids, bases or strong oxidants, the chemical properties become active. In case of strong acids, some chemical bonds in the molecule are attacked by protons, triggering structural rearrangement or functional group transformation; in case of strong bases, hydroxyl groups may participate in acid-base neutralization or nucleophilic substitution reactions; in case of strong oxidants, such as potassium permanganate, etc., the easily oxidized parts of the molecule, such as benzyl positions, may be oxidized to higher valence functional groups such as carboxyl groups.
When it comes to reactivity, the reactivity is highlighted due to the presence of functional groups such as fluorine atoms and hydroxyl groups. Fluorine atoms have high electronegativity, which reduces the electron cloud density of carbon atoms connected to them, which is conducive to the attack of nucleophilic reagents and thus participates in nucleophilic substitution reactions; hydroxyl groups, as active functional groups, can undergo esterification reactions, generate esters with carboxylic acids or acyl chlorides under the action of catalysts, and These reactive activities provide various possibilities for organic synthetic chemists to construct complex organic molecular structures, and have important application value in medicinal chemistry, materials science and other fields.
What should be paid attention to when storing and transporting 2-bromo-4,5-dichloronitrobenzene?
When storing and transporting 2-% cyanogen-4,5-difluorobenzyl benzene, many key matters need to be paid attention to.
When storing, the first priority is to choose the environment. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. This is because the substance may have certain chemical activity, high temperature or open flame can easily cause danger. If stored in a humid environment, or cause chemical reactions to occur, it will affect the quality.
Furthermore, the storage container cannot be ignored. Appropriate materials need to be selected to ensure a good seal. Prevent the intrusion of impurities such as air and moisture to maintain its chemical stability. For example, if the container is not well sealed, oxygen in the air may react with the substance and cause it to deteriorate.
During transportation, safety is the top priority. Be sure to strictly follow relevant transportation regulations and standards, and use professional transportation tools. Transportation vehicles should be equipped with corresponding fire equipment and emergency treatment equipment to prevent accidents.
At the same time, the substance should be properly packaged to prevent packaging damage due to bumps and collisions during transportation. Once the packaging is damaged, the substance leaks, or causes safety accidents and environmental pollution.
In addition, transportation personnel need to be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. In case of emergencies, they can respond quickly and correctly to reduce hazards.
In conclusion, 2-% cyanogen-4,5-difluorobenzylbenzene needs to be treated with caution and strictly controlled in terms of environment, container, packaging, and personnel during storage and transportation to ensure the safety of the entire process.
When storing, the first priority is to choose the environment. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. This is because the substance may have certain chemical activity, high temperature or open flame can easily cause danger. If stored in a humid environment, or cause chemical reactions to occur, it will affect the quality.
Furthermore, the storage container cannot be ignored. Appropriate materials need to be selected to ensure a good seal. Prevent the intrusion of impurities such as air and moisture to maintain its chemical stability. For example, if the container is not well sealed, oxygen in the air may react with the substance and cause it to deteriorate.
During transportation, safety is the top priority. Be sure to strictly follow relevant transportation regulations and standards, and use professional transportation tools. Transportation vehicles should be equipped with corresponding fire equipment and emergency treatment equipment to prevent accidents.
At the same time, the substance should be properly packaged to prevent packaging damage due to bumps and collisions during transportation. Once the packaging is damaged, the substance leaks, or causes safety accidents and environmental pollution.
In addition, transportation personnel need to be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. In case of emergencies, they can respond quickly and correctly to reduce hazards.
In conclusion, 2-% cyanogen-4,5-difluorobenzylbenzene needs to be treated with caution and strictly controlled in terms of environment, container, packaging, and personnel during storage and transportation to ensure the safety of the entire process.
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