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2-Bromo-4-Chloroiodobenzene
Linshang Chemical
|
HS Code |
236202 |
| Chemical Formula | C6H3BrClI |
| Molecular Weight | 329.35 |
| Appearance | Solid (Typical description, may vary) |
| Melting Point | Data may vary depending on purity |
| Boiling Point | Data may vary depending on purity |
| Density | Data may vary depending on conditions |
| Solubility In Water | Low (Organic halide, relatively hydrophobic) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Odor | May have a characteristic halogen - containing organic compound odor |
| Hazard Class | Harmful, may cause skin, eye, and respiratory irritation; toxic if swallowed |
As an accredited 2-Bromo-4-Chloroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 g of 2 - bromo - 4 - chloroiodobenzene packaged in a sealed glass bottle. |
| Storage | 2 - bromo - 4 - chloroiodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. Avoid exposure to light as it may cause decomposition. Label the storage container clearly to prevent misidentification. |
| Shipping | 2 - bromo - 4 - chloroiodobenzene is shipped in well - sealed, corrosion - resistant containers. It's transported under regulated conditions, avoiding exposure to heat, moisture, and incompatible substances to ensure safe transit. |
Competitive 2-Bromo-4-Chloroiodobenzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 2-Bromo-4-Chloroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the Chinese name of 2-bromo-4-chloroiodobenzene?
2-Bromo-4-chloroiodobenzene, this is the result of the naming of organic compounds. According to the naming rules of organic compounds, if there are multiple substituents on the benzene ring, their positions and names should be marked in a specific order. In this compound, there are three halogen atoms of bromine (Br), chlorine (Cl) and iodine (I) attached to the benzene ring. When naming
, the parent body is first determined to be benzene, and then the halogen atom is regarded as the substituent. In order to accurately indicate the position of the substituent, the carbon atom of the benzene ring is numbered. Starting from the carbon atom connected with the higher-priority substituent, it is numbered clockwise or counterclockwise, so that the sum of the
In this example, "2-bromo" means that the bromine atom is attached to the carbon atom at position 2 of the benzene ring, "4-chlorine" means that the chlorine atom is attached to the carbon atom at position 4, and "iodobenzene" means that the iodine atom is attached to the benzene ring. The overall name is 2-bromo-4-chloroiodobenzene. This nomenclature follows the organic compound nomenclature of the International Union of Pure and Applied Chemistry (IUPAC), which aims to achieve the standardization and uniqueness of organic compound nomenclature and facilitate communication and research in
, the parent body is first determined to be benzene, and then the halogen atom is regarded as the substituent. In order to accurately indicate the position of the substituent, the carbon atom of the benzene ring is numbered. Starting from the carbon atom connected with the higher-priority substituent, it is numbered clockwise or counterclockwise, so that the sum of the
In this example, "2-bromo" means that the bromine atom is attached to the carbon atom at position 2 of the benzene ring, "4-chlorine" means that the chlorine atom is attached to the carbon atom at position 4, and "iodobenzene" means that the iodine atom is attached to the benzene ring. The overall name is 2-bromo-4-chloroiodobenzene. This nomenclature follows the organic compound nomenclature of the International Union of Pure and Applied Chemistry (IUPAC), which aims to achieve the standardization and uniqueness of organic compound nomenclature and facilitate communication and research in
What is the chemical structure of 2-bromo-4-chloroiodobenzene?
2-Bromo-4-chloroiodobenzene is also known as a benzene compound. Among its molecules, the benzene group has three substituents of bromo, chloro, and iodo. Bromine is located in the second position of benzene, chlorine is in the fourth position, and iodine is also above benzene.
The basic framework of benzene is benzene, and the carbon atoms of the six-membered benzene are interconnected to each other in a common way to form a plane. Bromine atoms (Br), chlorine atoms (Cl), and iodine atoms (I) replace the atoms at specific positions on benzene. The two-position bromine atom changes the density of benzene. The four-position chlorine atom also affects the properties of benzene. The iodine atom also shapes the properties of this compound.
The property of this compound is due to the presence of trisubstituents, which makes its physical and chemical properties similar to that of benzene. The properties of the substituents, atomic hemi-atoms and other factors, and the properties of the molecules, melting boiling, and chemical reactivity. For example, the absorber effect of the atom can make the sub-cloud on the benzene atom biased towards the benzene atom, which decreases the chemical reactivity of the benzene, and the localization of the chemical reactance is also affected by the interaction of the polysubstituents. In addition, the chemical properties of 2-bromo-4-chloroiodobenzene are composed of benzene and the bromine, chlorine, and iodine substituents at specific sites. This gives it its specific chemical properties.
The basic framework of benzene is benzene, and the carbon atoms of the six-membered benzene are interconnected to each other in a common way to form a plane. Bromine atoms (Br), chlorine atoms (Cl), and iodine atoms (I) replace the atoms at specific positions on benzene. The two-position bromine atom changes the density of benzene. The four-position chlorine atom also affects the properties of benzene. The iodine atom also shapes the properties of this compound.
The property of this compound is due to the presence of trisubstituents, which makes its physical and chemical properties similar to that of benzene. The properties of the substituents, atomic hemi-atoms and other factors, and the properties of the molecules, melting boiling, and chemical reactivity. For example, the absorber effect of the atom can make the sub-cloud on the benzene atom biased towards the benzene atom, which decreases the chemical reactivity of the benzene, and the localization of the chemical reactance is also affected by the interaction of the polysubstituents. In addition, the chemical properties of 2-bromo-4-chloroiodobenzene are composed of benzene and the bromine, chlorine, and iodine substituents at specific sites. This gives it its specific chemical properties.
What are the physical properties of 2-bromo-4-chloroiodobenzene?
2-Bromo-4-chloroiodobenzene is an organohalogenated aromatic hydrocarbon with unique physical properties. It is a solid, and the melting and boiling point varies depending on the force between molecules. Due to the large relative molecular weight and the existence of van der Waals force between molecules, the melting point is about 60-70 ° C, and the boiling point is about 280-290 ° C.
This compound is insoluble in water, because water is a polar molecule, while 2-bromo-4-chloroiodobenzene is non-polar or weakly polar, and it is difficult to dissolve in water according to the principle of "similar miscibility". However, it is soluble in common organic solvents, such as ether, chloroform, dichloromethane, etc., because these organic solvents are similar to its polarity.
The compound has a certain density. Because it contains halogen atoms with relatively large atomic mass such as bromine, chlorine, and iodine, the density is greater than that of water, about 2.3-2.5 g/cm ³.
Its appearance is mostly white to light yellow crystalline powder. When pure, the color is lighter, and when it contains impurities, the color may be deepened. The chemical properties are relatively stable at room temperature and pressure, but under specific conditions such as light, high temperature, or catalyst, halogen atoms can undergo reactions such as substitution and elimination. Because it contains a variety of halogen atoms, it may have potential effects on the environment and organisms. Caution is required when using and handling.
This compound is insoluble in water, because water is a polar molecule, while 2-bromo-4-chloroiodobenzene is non-polar or weakly polar, and it is difficult to dissolve in water according to the principle of "similar miscibility". However, it is soluble in common organic solvents, such as ether, chloroform, dichloromethane, etc., because these organic solvents are similar to its polarity.
The compound has a certain density. Because it contains halogen atoms with relatively large atomic mass such as bromine, chlorine, and iodine, the density is greater than that of water, about 2.3-2.5 g/cm ³.
Its appearance is mostly white to light yellow crystalline powder. When pure, the color is lighter, and when it contains impurities, the color may be deepened. The chemical properties are relatively stable at room temperature and pressure, but under specific conditions such as light, high temperature, or catalyst, halogen atoms can undergo reactions such as substitution and elimination. Because it contains a variety of halogen atoms, it may have potential effects on the environment and organisms. Caution is required when using and handling.
What are the main uses of 2-bromo-4-chloroiodobenzene?
2 - bromo - 4 - chloroiodobenzene is also an organic compound. It has a wide range of uses and plays an important role in the field of organic synthesis.
First, it can be used as an intermediate in pharmaceutical synthesis. Cover the creation of medicine, often rely on organic compounds as starting materials, and undergo multi-step reactions to form target drugs. 2 - bromo - 4 - chloroiodobenzene has a unique structure. Its halogen atoms can participate in reactions such as nucleophilic substitution. After ingeniously designing the reaction path, various functional groups can be introduced, and then complex pharmaceutical molecular structures can be constructed, laying the foundation for the research and development of new drugs.
Second, it also has applications in the field of materials science. When preparing organic materials with specific properties, their structural units can be introduced into the polymer chain by participating in polymerization reactions, etc., to impart special properties such as optics and electricity to the materials. For example, synthesizing polymer materials with specific photoelectric properties can be applied to organic Light Emitting Diodes (OLEDs), solar cells and other devices to improve their performance.
Third, it also plays a role in pesticide synthesis. Through a reasonable reaction, it can be converted into pesticide active ingredients with insecticidal and bactericidal effects. Because the structure of halobenzene can affect the biological activity and stability of the compound, it can meet the needs of pesticides for high efficiency, low toxicity and long-term performance.
In summary, 2-bromo-4-chloroiodobenzene, with its unique chemical structure, has shown important application value in many fields such as medicine, materials, and pesticides, and has promoted scientific and technological progress and industrial development in related fields.
First, it can be used as an intermediate in pharmaceutical synthesis. Cover the creation of medicine, often rely on organic compounds as starting materials, and undergo multi-step reactions to form target drugs. 2 - bromo - 4 - chloroiodobenzene has a unique structure. Its halogen atoms can participate in reactions such as nucleophilic substitution. After ingeniously designing the reaction path, various functional groups can be introduced, and then complex pharmaceutical molecular structures can be constructed, laying the foundation for the research and development of new drugs.
Second, it also has applications in the field of materials science. When preparing organic materials with specific properties, their structural units can be introduced into the polymer chain by participating in polymerization reactions, etc., to impart special properties such as optics and electricity to the materials. For example, synthesizing polymer materials with specific photoelectric properties can be applied to organic Light Emitting Diodes (OLEDs), solar cells and other devices to improve their performance.
Third, it also plays a role in pesticide synthesis. Through a reasonable reaction, it can be converted into pesticide active ingredients with insecticidal and bactericidal effects. Because the structure of halobenzene can affect the biological activity and stability of the compound, it can meet the needs of pesticides for high efficiency, low toxicity and long-term performance.
In summary, 2-bromo-4-chloroiodobenzene, with its unique chemical structure, has shown important application value in many fields such as medicine, materials, and pesticides, and has promoted scientific and technological progress and industrial development in related fields.
What are the preparation methods of 2-bromo-4-chloroiodobenzene?
2-Bromo-4-chloroiodobenzene is an organic halogenated aromatic hydrocarbon. There are several common methods for preparing it:
First, aniline is used as the starting material. First, aniline undergoes a diazotization reaction, using sodium nitrite and hydrochloric acid as reagents to form a diazonium salt at low temperature. Subsequently, cuprous bromide and hydrobromic acid are added to this diazonium salt solution, which can introduce bromine atoms to obtain bromobenzene derivatives. After that, through a nitration reaction, nitro groups are introduced at suitable positions with concentrated sulfuric acid and concentrated nitric acid as acid mixing reagents. Then, through a reduction reaction, iron powder and hydrochloric acid or other suitable reducing agents are reduced to amino groups. Then, the diazotization reaction is carried out again, this time adding potassium iodide, thereby introducing iodine atoms. Finally, 2-bromo-4-chloroiodobenzene can be obtained by chlorination reaction, for example, chlorine gas and a suitable catalyst, and chlorine atoms are introduced at the appropriate position.
Second, benzene is used as the starting material. First, a halogenation reaction is carried out, and bromine and iron powder are used as catalysts to obtain bromobenzene. After that, a chlorine-containing group is introduced into the benzene ring using chloroacetyl chloride and anhydrous aluminum trichloride as reagents by using the Fu-G reaction. This chlorine-containing group is converted into a suitable iodine-substituted group through a series of reactions, such as hydrolysis first, and then conversion into a suitable leaving group. Finally, it reacts with iodizing reagents (such as sodium iodide, etc.) to introduce iodine atoms. After appropriate modification and conversion, the target product can be obtained.
Third, m-chloroaniline is used as raw material. First, the diazotization reaction is carried out, and then the iodine atom is introduced into the reaction with potassium iodide to obtain m-chloroiodobenzene. Then the m-chloroiodobenzene is brominated, and the bromine atom is introduced at a specific position with a suitable catalyst to obtain 2-bromo-4-chloroiodobenzene.
Each of these preparation methods has its own advantages and disadvantages, and the experimenter should choose according to the actual demand, availability of raw materials, cost and other factors.
First, aniline is used as the starting material. First, aniline undergoes a diazotization reaction, using sodium nitrite and hydrochloric acid as reagents to form a diazonium salt at low temperature. Subsequently, cuprous bromide and hydrobromic acid are added to this diazonium salt solution, which can introduce bromine atoms to obtain bromobenzene derivatives. After that, through a nitration reaction, nitro groups are introduced at suitable positions with concentrated sulfuric acid and concentrated nitric acid as acid mixing reagents. Then, through a reduction reaction, iron powder and hydrochloric acid or other suitable reducing agents are reduced to amino groups. Then, the diazotization reaction is carried out again, this time adding potassium iodide, thereby introducing iodine atoms. Finally, 2-bromo-4-chloroiodobenzene can be obtained by chlorination reaction, for example, chlorine gas and a suitable catalyst, and chlorine atoms are introduced at the appropriate position.
Second, benzene is used as the starting material. First, a halogenation reaction is carried out, and bromine and iron powder are used as catalysts to obtain bromobenzene. After that, a chlorine-containing group is introduced into the benzene ring using chloroacetyl chloride and anhydrous aluminum trichloride as reagents by using the Fu-G reaction. This chlorine-containing group is converted into a suitable iodine-substituted group through a series of reactions, such as hydrolysis first, and then conversion into a suitable leaving group. Finally, it reacts with iodizing reagents (such as sodium iodide, etc.) to introduce iodine atoms. After appropriate modification and conversion, the target product can be obtained.
Third, m-chloroaniline is used as raw material. First, the diazotization reaction is carried out, and then the iodine atom is introduced into the reaction with potassium iodide to obtain m-chloroiodobenzene. Then the m-chloroiodobenzene is brominated, and the bromine atom is introduced at a specific position with a suitable catalyst to obtain 2-bromo-4-chloroiodobenzene.
Each of these preparation methods has its own advantages and disadvantages, and the experimenter should choose according to the actual demand, availability of raw materials, cost and other factors.
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