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2-(Bromomethyl)-1,4-Dichloro-Benzene
Linshang Chemical
|
HS Code |
113471 |
| Chemical Formula | C7H5BrCl2 |
| Molar Mass | 223.92 g/mol |
| Appearance | Solid (usually white or off - white) |
| Melting Point | Data may vary, typically in a certain temperature range |
| Boiling Point | Data may vary, related to its molecular structure |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, chloroform |
| Density | Data may vary depending on conditions |
| Vapor Pressure | Low vapor pressure at normal conditions |
| Stability | Stable under normal conditions but can react under certain chemical environments |
| Flash Point | Data may vary, related to its flammability characteristics |
As an accredited 2-(Bromomethyl)-1,4-Dichloro-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2-(bromomethyl)-1,4 - dichloro - benzene in a sealed, chemical - resistant bottle. |
| Storage | 2-(Bromomethyl)-1,4 - dichloro - benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and bases to avoid chemical reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 2-(Bromomethyl)-1,4 - dichloro - benzene is a chemical. Shipping requires proper packaging in compliant containers to prevent leakage. It must follow hazardous materials regulations, with accurate labeling for safe transportation. |
Competitive 2-(Bromomethyl)-1,4-Dichloro-Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 2-(Bromomethyl)-1,4-Dichloro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2- (bromomethyl) -1,4-dichloro-benzene?
2-%28bromomethyl%29-1%2C4-dichloro-benzene is 2- (bromomethyl) -1,4-dichlorobenzene, which has a wide range of uses.
In the field of organic synthesis, it can be used as a key intermediate. Due to its active properties of bromomethyl and dichlorophenyl groups in the molecule, it can interact with various nucleophiles through many chemical reactions, such as nucleophilic substitution reactions, etc., and then derive various organic compounds with rich and diverse structures. For example, it can react with alcohols in an alkaline environment to form ether compounds; it can also react with nitrogen-containing nucleophiles to construct important structures such as nitrogen-containing heterocycles. It is indispensable in the field of new drug molecules and total synthesis of natural products.
In the field of materials science, this compound has also emerged. With its unique chemical structure, it can participate in the synthesis process of polymer materials. For example, by polymerizing with specific monomers, polymer materials are endowed with novel properties, such as improving the thermal stability and mechanical properties of materials, or endowing them with special optical and electrical properties, etc., which hold broad application prospects in the field of research and development and preparation of advanced materials.
In pesticide chemistry, 2- (bromomethyl) -1,4-dichlorobenzene also has important uses. Due to its structural properties, it can be used to synthesize pesticide ingredients with specific biological activities, showing good inhibition or killing effects on certain pests and diseases, assisting in the control of pests and diseases in agricultural production, and contributing to ensuring crop yield and quality.
In the field of organic synthesis, it can be used as a key intermediate. Due to its active properties of bromomethyl and dichlorophenyl groups in the molecule, it can interact with various nucleophiles through many chemical reactions, such as nucleophilic substitution reactions, etc., and then derive various organic compounds with rich and diverse structures. For example, it can react with alcohols in an alkaline environment to form ether compounds; it can also react with nitrogen-containing nucleophiles to construct important structures such as nitrogen-containing heterocycles. It is indispensable in the field of new drug molecules and total synthesis of natural products.
In the field of materials science, this compound has also emerged. With its unique chemical structure, it can participate in the synthesis process of polymer materials. For example, by polymerizing with specific monomers, polymer materials are endowed with novel properties, such as improving the thermal stability and mechanical properties of materials, or endowing them with special optical and electrical properties, etc., which hold broad application prospects in the field of research and development and preparation of advanced materials.
In pesticide chemistry, 2- (bromomethyl) -1,4-dichlorobenzene also has important uses. Due to its structural properties, it can be used to synthesize pesticide ingredients with specific biological activities, showing good inhibition or killing effects on certain pests and diseases, assisting in the control of pests and diseases in agricultural production, and contributing to ensuring crop yield and quality.
What are the physical properties of 2- (bromomethyl) -1,4-dichloro-benzene?
2-%28bromomethyl%29-1%2C4-dichloro-benzene is 2- (bromomethyl) -1,4 -dichlorobenzene, and its physical properties are as follows:
In terms of view, it is a colorless to light yellow liquid with an irritating odor. As for the melting and boiling point, the melting point is about [specific value] ° C, and the boiling point is around [specific value] ° C. Under specific conditions, the two have a great influence on its existence and changes.
When it comes to solubility, 2- (bromomethyl) -1,4 -dichlorobenzene is insoluble in water, but it can be miscible with many organic solvents, such as ethanol, ether, acetone, etc. This characteristic is due to the difference between its molecular structure and that of water, which makes it difficult for the two to be compatible with each other.
In terms of density, it is about [specific value] g/cm ³, which is slightly heavier than water. This density characteristic is of great significance when it comes to operations such as liquid-liquid separation.
2- (bromomethyl) -1,4-dichlorobenzene has relatively high stability and is not prone to spontaneous chemical changes at room temperature and pressure. In case of open flames and hot topics, there will be a risk of combustion, and harmful gases such as bromine and chlorine will be released when burning. At the same time, it has certain toxicity. If it is exposed to or inhaled by the human body, it may damage health. When using and storing, strict protective measures must be taken.
In terms of view, it is a colorless to light yellow liquid with an irritating odor. As for the melting and boiling point, the melting point is about [specific value] ° C, and the boiling point is around [specific value] ° C. Under specific conditions, the two have a great influence on its existence and changes.
When it comes to solubility, 2- (bromomethyl) -1,4 -dichlorobenzene is insoluble in water, but it can be miscible with many organic solvents, such as ethanol, ether, acetone, etc. This characteristic is due to the difference between its molecular structure and that of water, which makes it difficult for the two to be compatible with each other.
In terms of density, it is about [specific value] g/cm ³, which is slightly heavier than water. This density characteristic is of great significance when it comes to operations such as liquid-liquid separation.
2- (bromomethyl) -1,4-dichlorobenzene has relatively high stability and is not prone to spontaneous chemical changes at room temperature and pressure. In case of open flames and hot topics, there will be a risk of combustion, and harmful gases such as bromine and chlorine will be released when burning. At the same time, it has certain toxicity. If it is exposed to or inhaled by the human body, it may damage health. When using and storing, strict protective measures must be taken.
What are the chemical properties of 2- (bromomethyl) -1,4-dichloro-benzene?
2- (bromomethyl) -1,4-dichlorobenzene is one of the organic compounds. Its physical properties, at room temperature, are mostly solid, with a certain melting point and boiling point, but the specific value varies according to the preparation method and purity. Looking at its appearance, or white to light yellow crystalline powder, with a slight special smell. In terms of solubility, it is slightly soluble in water, because it is an organic halogen, with certain hydrophobicity; however, it can be soluble in common organic solvents, such as ethanol, ether, chloroform, etc. This is due to the principle of "similar miscibility", and its molecular structure has a similar polarity to that of organic solvents.
In terms of its chemical properties, this compound is active and abnormal. Bromomethyl is an active functional group, prone to nucleophilic substitution. In the case of nucleophilic reagents, such as alcohols, amines, mercaptans, etc., bromine atoms can be replaced by nucleophilic reagent groups, thereby deriving a variety of new compounds. If it is co-heated with alcohols under basic conditions, corresponding ether compounds can be formed; when reacted with amines, amine substitution products are obtained. This reaction is an important means for constructing new carbon-heteroatom bonds in the field of organic synthesis.
Furthermore, although the two chlorine atoms on the benzene ring are less active than the bromo-methyl group, they can also participate in the reaction under specific conditions. For example, under the catalysis of strong Lewis acid, the electrophilic substitution reaction on the aromatic ring can be carried out, and the chlorine atom can be replaced by other groups, which is of great significance for introducing specific functional groups and modifying molecular structures. And because of its halogen-containing atoms, under appropriate conditions, elimination reactions can occur, forming unsaturated bonds, providing more possible paths for organic synthesis.
And because of the existence of halogen atoms in its structure, 2- (bromomethyl) -1,4-dichlorobenzene can be used as a halogen source in some chemical reactions, participating in halogenation reactions, and contributing halogen atoms to the construction of halogen-containing organic molecules. It is widely used in pharmaceutical chemistry, materials science and other fields.
In terms of its chemical properties, this compound is active and abnormal. Bromomethyl is an active functional group, prone to nucleophilic substitution. In the case of nucleophilic reagents, such as alcohols, amines, mercaptans, etc., bromine atoms can be replaced by nucleophilic reagent groups, thereby deriving a variety of new compounds. If it is co-heated with alcohols under basic conditions, corresponding ether compounds can be formed; when reacted with amines, amine substitution products are obtained. This reaction is an important means for constructing new carbon-heteroatom bonds in the field of organic synthesis.
Furthermore, although the two chlorine atoms on the benzene ring are less active than the bromo-methyl group, they can also participate in the reaction under specific conditions. For example, under the catalysis of strong Lewis acid, the electrophilic substitution reaction on the aromatic ring can be carried out, and the chlorine atom can be replaced by other groups, which is of great significance for introducing specific functional groups and modifying molecular structures. And because of its halogen-containing atoms, under appropriate conditions, elimination reactions can occur, forming unsaturated bonds, providing more possible paths for organic synthesis.
And because of the existence of halogen atoms in its structure, 2- (bromomethyl) -1,4-dichlorobenzene can be used as a halogen source in some chemical reactions, participating in halogenation reactions, and contributing halogen atoms to the construction of halogen-containing organic molecules. It is widely used in pharmaceutical chemistry, materials science and other fields.
What are the synthesis methods of 2- (bromomethyl) -1,4-dichloro-benzene?
The method of preparing 2 - (bromomethyl) -1,4 - dichlorobenzene has various paths in the past. One is to start with 1,4 - dichlorotoluene and react with N - bromosuccinimide (NBS) in the presence of an initiator. Among them, benzoyl peroxide is often used as an initiator, and it is heated and refluxed in an inert solvent such as carbon tetrachloride. NBS will provide bromine radicals, capture the hydrogen atom on 1,4 - dichlorotoluene methyl, and then generate benzyl radicals. This radical quickly combines with bromine atoms to obtain 2 - (bromomethyl) -1,4 - dichlorobenzene. The beauty of this approach is that the reaction selectivity is good, and the target product can be obtained better.
There are also 1,4-dichlorobenzene as the starting material, the first methyl is introduced, such as chloromethane and anhydrous aluminum trichloride as the reagent, and the Fu-gram alkylation reaction is carried out to obtain 1,4-dichlorotoluene. Then as above, it reacts with NBS and is brominated to obtain the target. This two-step method, although the process is slightly complicated, the raw materials are common and easy to obtain.
There are also those who use 1,4-dichlorobenzoic acid as the starting material, which is first reduced to 1,4-dichlorobenzanol, and strong reducing agents such as lithium aluminum hydride can be used. Then react with hydrobromic acid or phosphorus tribromide to replace the hydroxyl group with a bromine atom to obtain 2- (bromomethyl) -1,4-dichlorobenzene. This path requires attention to the conditions under which the reducing agent is used, and the subsequent halogenation steps also need to be precisely controlled to achieve good yields.
There are also 1,4-dichlorobenzene as the starting material, the first methyl is introduced, such as chloromethane and anhydrous aluminum trichloride as the reagent, and the Fu-gram alkylation reaction is carried out to obtain 1,4-dichlorotoluene. Then as above, it reacts with NBS and is brominated to obtain the target. This two-step method, although the process is slightly complicated, the raw materials are common and easy to obtain.
There are also those who use 1,4-dichlorobenzoic acid as the starting material, which is first reduced to 1,4-dichlorobenzanol, and strong reducing agents such as lithium aluminum hydride can be used. Then react with hydrobromic acid or phosphorus tribromide to replace the hydroxyl group with a bromine atom to obtain 2- (bromomethyl) -1,4-dichlorobenzene. This path requires attention to the conditions under which the reducing agent is used, and the subsequent halogenation steps also need to be precisely controlled to achieve good yields.
2- (bromomethyl) -1,4-dichloro-benzene What are the precautions in storage and transportation?
2-%28bromomethyl%29-1%2C4-dichloro-benzene is 2- (bromomethyl) -1,4 -dichlorobenzene. When storing and transporting this substance, pay attention to many matters.
First, its chemical properties, 2- (bromomethyl) -1,4 -dichlorobenzene has a certain reactivity, and is at risk of explosion in case of heat, open flame or oxidant. Therefore, when storing, it is necessary to choose a cool, dry and well-ventilated place, which is decidedly isolated from the fire and heat source, and away from strong oxidants. The temperature of the warehouse should be strictly controlled to prevent the high temperature from increasing its reactivity and causing danger.
Furthermore, because of its certain toxicity, it can cause harm to human health, such as inhalation, ingestion or absorption through the skin, which can damage health. During transportation and storage, be sure to ensure that the packaging is intact to avoid leakage. When operating, the staff should be in front of appropriate protective equipment, such as gas masks, protective gloves and protective clothing, to prevent contact.
Packaging also needs to be cautious. Packaging materials that meet safety standards should be used to ensure good sealing, can effectively resist collision, vibration and extrusion, and avoid material leakage caused by packaging damage.
During transportation, to choose a compliance transportation vehicle, the transportation vehicle needs to be equipped with corresponding fire equipment and leakage emergency treatment equipment. When planning the route, avoid sensitive areas such as water sources and densely populated areas. During transportation, pay close attention to the condition of the goods, and regularly check whether the packaging is in good condition and whether there are any signs of leakage.
When storing, it should also be placed separately from other chemicals according to the chemical storage specifications, and must not be mixed to prevent chemical reactions. At the same time, do a good job in inventory management, and record the time and quantity of warehousing in detail for traceability and control. In this way, the safety of 2 - (bromomethyl) -1,4 - dichlorobenzene during storage and transportation is guaranteed.
First, its chemical properties, 2- (bromomethyl) -1,4 -dichlorobenzene has a certain reactivity, and is at risk of explosion in case of heat, open flame or oxidant. Therefore, when storing, it is necessary to choose a cool, dry and well-ventilated place, which is decidedly isolated from the fire and heat source, and away from strong oxidants. The temperature of the warehouse should be strictly controlled to prevent the high temperature from increasing its reactivity and causing danger.
Furthermore, because of its certain toxicity, it can cause harm to human health, such as inhalation, ingestion or absorption through the skin, which can damage health. During transportation and storage, be sure to ensure that the packaging is intact to avoid leakage. When operating, the staff should be in front of appropriate protective equipment, such as gas masks, protective gloves and protective clothing, to prevent contact.
Packaging also needs to be cautious. Packaging materials that meet safety standards should be used to ensure good sealing, can effectively resist collision, vibration and extrusion, and avoid material leakage caused by packaging damage.
During transportation, to choose a compliance transportation vehicle, the transportation vehicle needs to be equipped with corresponding fire equipment and leakage emergency treatment equipment. When planning the route, avoid sensitive areas such as water sources and densely populated areas. During transportation, pay close attention to the condition of the goods, and regularly check whether the packaging is in good condition and whether there are any signs of leakage.
When storing, it should also be placed separately from other chemicals according to the chemical storage specifications, and must not be mixed to prevent chemical reactions. At the same time, do a good job in inventory management, and record the time and quantity of warehousing in detail for traceability and control. In this way, the safety of 2 - (bromomethyl) -1,4 - dichlorobenzene during storage and transportation is guaranteed.
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