Linshang Chemical
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2-(Bromomethyl)-4-Chloro-1-Fluorobenzene
Linshang Chemical
|
HS Code |
287199 |
| Chemical Formula | C7H5BrClF |
| Molecular Weight | 223.47 |
| Appearance | Typically a colorless to pale yellow liquid |
| Boiling Point | Approximately 220 - 230 °C (estimated) |
| Density | Estimated around 1.6 - 1.7 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Pungency | May have a pungent odor |
| Reactivity | Reactive towards nucleophiles due to bromomethyl group |
As an accredited 2-(Bromomethyl)-4-Chloro-1-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 2-(bromomethyl)-4-chloro-1-fluorobenzene packaged in a sealed glass bottle. |
| Storage | 2-(Bromomethyl)-4-chloro-1-fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, bases, and reactive chemicals to avoid potential reactions. Label the storage container clearly for easy identification. |
| Shipping | 2-(Bromomethyl)-4-chloro-1-fluorobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring proper handling to prevent leakage and maintain safety during transit. |
Competitive 2-(Bromomethyl)-4-Chloro-1-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-(Bromomethyl)-4-Chloro-1-Fluorobenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-(Bromomethyl)-4-Chloro-1-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2- (bromomethyl) -4-chloro-1-fluorobenzene?
2-%28bromomethyl%29-4-chloro-1-fluorobenzene, the Chinese name is 2- (bromomethyl) -4 -chloro-1 -fluorobenzene. This compound is used in the field of chemical synthesis and is often used in synthesis.
First, it can be used as an important raw material in chemical research. The compound is the essence of the synthesis of heavy molecules. This compound contains special groups such as bromomethyl, chlorine, and fluorine, which can introduce specific molecules into the molecule. For example, fluorine atoms can increase the lipid solubility of the molecule, making it easier to penetrate the biofilm, which can improve the bioavailability of the compound. Bromomethyl has good reaction activity and can be replaced by other compounds containing specific functionalities.
Second, it also has its application in the field of materials science. It can be used in the synthesis of polymeric materials, and it can be introduced into the polymer by chemical reaction. Because of the elemental atoms it contains, it can change the physical properties of the material, such as improving the flame retardancy of the material. In the synthesis of materials with special optical properties, the special properties of this compound can affect the performance of the material, and affect the light absorption and emission characteristics of the material, providing the possibility of developing new optical materials.
Third, in the field of chemical synthesis, it can be used as an important part of the synthesis of high efficiency and low toxicity. Use its anti-activity to synthesize molecules with specific chemical, weeding or antibacterial activities. For example, through a reasonable anti-chemical approach, it is possible to obtain new products with biological activity and environmental friendliness through the anti-chemical reaction of compounds containing nitrogen and sulfur.
First, it can be used as an important raw material in chemical research. The compound is the essence of the synthesis of heavy molecules. This compound contains special groups such as bromomethyl, chlorine, and fluorine, which can introduce specific molecules into the molecule. For example, fluorine atoms can increase the lipid solubility of the molecule, making it easier to penetrate the biofilm, which can improve the bioavailability of the compound. Bromomethyl has good reaction activity and can be replaced by other compounds containing specific functionalities.
Second, it also has its application in the field of materials science. It can be used in the synthesis of polymeric materials, and it can be introduced into the polymer by chemical reaction. Because of the elemental atoms it contains, it can change the physical properties of the material, such as improving the flame retardancy of the material. In the synthesis of materials with special optical properties, the special properties of this compound can affect the performance of the material, and affect the light absorption and emission characteristics of the material, providing the possibility of developing new optical materials.
Third, in the field of chemical synthesis, it can be used as an important part of the synthesis of high efficiency and low toxicity. Use its anti-activity to synthesize molecules with specific chemical, weeding or antibacterial activities. For example, through a reasonable anti-chemical approach, it is possible to obtain new products with biological activity and environmental friendliness through the anti-chemical reaction of compounds containing nitrogen and sulfur.
What are the physical properties of 2- (bromomethyl) -4-chloro-1-fluorobenzene
2-%28bromomethyl%29-4-chloro-1-fluorobenzene is 2- (bromomethyl) -4-chloro-1-fluorobenzene, which is an organic compound. Its physical properties are quite critical and are of great significance for applications in chemical and pharmaceutical fields.
Looking at its properties, under normal circumstances, 2- (bromomethyl) -4-chloro-1-fluorobenzene is mostly a colorless to light yellow liquid. This color feature is easy to observe and distinguish in actual operation. It has a special odor, but the specific description of the odor is always attributed to the unique identification of the substance due to differences or differences in individual olfactory senses.
The melting point is [specific melting point value], and the boiling point is [specific boiling point value]. Melting point and boiling point are important physical properties of a substance. The melting point determines the temperature at which it changes from solid to liquid state, and the boiling point is related to the conditions for liquid to gas state. Knowing both is extremely helpful for the separation, purification and storage of substances. For example, in the distillation and purification process, the appropriate temperature can be set according to the boiling point to achieve the purpose of separation.
The density of 2 - (bromomethyl) - 4 - chloro-1 - fluorobenzene is [specific density value]. The determination of density is of great significance for the quantitative analysis of substances and the study of mixed systems. For example, when preparing a solution, the required amount of substance can be accurately calculated by density.
In terms of solubility, it is insoluble in water, but soluble in common organic solvents such as ethanol, ether, dichloromethane, etc. This solubility characteristic makes the substance in the organic synthesis reaction, choose a suitable organic solvent to build the reaction environment, which is conducive to the smooth progress of the reaction.
In addition, its vapor pressure is also one of the important physical properties. The vapor pressure reflects the difficulty of volatilization of substances. The vapor pressure of 2- (bromomethyl) -4-chloro-1-fluorobenzene is [specific vapor pressure value] at a specific temperature, which has a great impact on the safety of storage and use. If the vapor pressure is too high, it is necessary to pay attention to sealing and ventilation during storage to prevent its volatilization from causing danger.
Looking at its properties, under normal circumstances, 2- (bromomethyl) -4-chloro-1-fluorobenzene is mostly a colorless to light yellow liquid. This color feature is easy to observe and distinguish in actual operation. It has a special odor, but the specific description of the odor is always attributed to the unique identification of the substance due to differences or differences in individual olfactory senses.
The melting point is [specific melting point value], and the boiling point is [specific boiling point value]. Melting point and boiling point are important physical properties of a substance. The melting point determines the temperature at which it changes from solid to liquid state, and the boiling point is related to the conditions for liquid to gas state. Knowing both is extremely helpful for the separation, purification and storage of substances. For example, in the distillation and purification process, the appropriate temperature can be set according to the boiling point to achieve the purpose of separation.
The density of 2 - (bromomethyl) - 4 - chloro-1 - fluorobenzene is [specific density value]. The determination of density is of great significance for the quantitative analysis of substances and the study of mixed systems. For example, when preparing a solution, the required amount of substance can be accurately calculated by density.
In terms of solubility, it is insoluble in water, but soluble in common organic solvents such as ethanol, ether, dichloromethane, etc. This solubility characteristic makes the substance in the organic synthesis reaction, choose a suitable organic solvent to build the reaction environment, which is conducive to the smooth progress of the reaction.
In addition, its vapor pressure is also one of the important physical properties. The vapor pressure reflects the difficulty of volatilization of substances. The vapor pressure of 2- (bromomethyl) -4-chloro-1-fluorobenzene is [specific vapor pressure value] at a specific temperature, which has a great impact on the safety of storage and use. If the vapor pressure is too high, it is necessary to pay attention to sealing and ventilation during storage to prevent its volatilization from causing danger.
What are the synthesis methods of 2- (bromomethyl) -4-chloro-1-fluorobenzene
The method of synthesizing 2 - (bromomethyl) -4 -chloro-1 -fluorobenzene depends on the method of organic synthesis. One method can be started by the corresponding benzoic acid derivative. First, benzoic acid is halogenated to introduce chlorine and fluorine atoms at specific positions in the benzene ring. If an appropriate halogenation reagent is used, under suitable reaction conditions, the hydrogen atoms on the benzene ring are replaced by chlorine and fluorine to obtain benzoic acid containing chlorine and fluorine.
The carboxyl group is converted to bromomethyl. The carboxyl group can be reduced to an alcohol hydroxyl group first, and it is often reacted in an anhydrous environment with strong reducing agents such as lithium aluminum hydride to obtain compounds containing hydroxyl groups. Then hydrobromic acid or brominating reagents, such as phosphorus tribromide, are used to react with it, and the hydroxyl group is replaced by a bromine atom to obtain 2- (bromomethyl) -4 -chloro-1 -fluorobenzene.
Another method can be started from halobenzene. Using halobenzene containing chlorine and fluorine as raw materials, methyl is introduced through Fu-gram alkylation reaction. Usually halomethane is reacted with halobenzene under the catalysis of Lewis acid such as anhydrous aluminum trichloride to obtain methyl-containing chlorofluorobenzene. Then N-bromosuccinimide (NBS) and an initiator such as benzoyl peroxide are used to make methyl bromide under light or heating conditions to obtain the target product.
When operating, all reaction conditions must be carefully regulated. Temperature, reaction time, reagent dosage, etc., are all related to the yield and selectivity of the reaction. If the halogenation reaction, the temperature is too high or the reagent is too high, it may cause the formation of polyhalogenated by-products; during the reduction reaction, the dosage of lithium aluminum hydride must be accurate to prevent excessive reduction. And after each step of the reaction, it is often necessary to separate and purify, such as distillation, recrystallization, column chromatography, etc., to obtain a pure product, and then 2 - (bromomethyl) -4 -chloro-1 -fluorobenzene can be obtained.
The carboxyl group is converted to bromomethyl. The carboxyl group can be reduced to an alcohol hydroxyl group first, and it is often reacted in an anhydrous environment with strong reducing agents such as lithium aluminum hydride to obtain compounds containing hydroxyl groups. Then hydrobromic acid or brominating reagents, such as phosphorus tribromide, are used to react with it, and the hydroxyl group is replaced by a bromine atom to obtain 2- (bromomethyl) -4 -chloro-1 -fluorobenzene.
Another method can be started from halobenzene. Using halobenzene containing chlorine and fluorine as raw materials, methyl is introduced through Fu-gram alkylation reaction. Usually halomethane is reacted with halobenzene under the catalysis of Lewis acid such as anhydrous aluminum trichloride to obtain methyl-containing chlorofluorobenzene. Then N-bromosuccinimide (NBS) and an initiator such as benzoyl peroxide are used to make methyl bromide under light or heating conditions to obtain the target product.
When operating, all reaction conditions must be carefully regulated. Temperature, reaction time, reagent dosage, etc., are all related to the yield and selectivity of the reaction. If the halogenation reaction, the temperature is too high or the reagent is too high, it may cause the formation of polyhalogenated by-products; during the reduction reaction, the dosage of lithium aluminum hydride must be accurate to prevent excessive reduction. And after each step of the reaction, it is often necessary to separate and purify, such as distillation, recrystallization, column chromatography, etc., to obtain a pure product, and then 2 - (bromomethyl) -4 -chloro-1 -fluorobenzene can be obtained.
2- (bromomethyl) -4-chloro-1-fluorobenzene during storage and transportation
2-%28bromomethyl%29-4-chloro-1-fluorobenzene, it is also an organic compound. When storing and transporting, many things need to be paid attention to.
The first word of storage, this compound should be stored in a cool, dry and well-ventilated place. It covers its properties or is affected by changes in temperature and humidity. High temperature or humidity can easily cause it to deteriorate and damage its quality. Furthermore, it must be placed separately from oxidizing agents, strong alkalis, etc. If this compound encounters them, it may cause a violent chemical reaction, or even cause a dangerous accident. The storage place should be clearly marked to show that it is a dangerous chemical, so that everyone knows its risk and prevent accidental touch and misuse.
As for transportation, the transportation vehicle must have the corresponding qualifications. Drivers and escorts should also be professionally trained to be familiar with the characteristics of this compound and emergency treatment methods. During transportation, ensure that the container is stable and does not leak. In case of poor road conditions, it is necessary to drive slowly and steadily to prevent the container from being damaged due to bumps. If a leak unfortunately occurs, do not panic, and deal with it according to the plan as soon as possible. First evacuate the surrounding people and set up warning signs to prevent unrelated people from approaching. Then according to the leakage situation, take appropriate measures, such as covering and absorbing with sand and other substances, or neutralizing with specific chemicals.
In short, 2-%28bromomethyl%29-4-chloro-1-fluorobenzene in storage and transportation, it is necessary to strictly abide by the regulations and operate carefully to ensure safety and avoid danger.
The first word of storage, this compound should be stored in a cool, dry and well-ventilated place. It covers its properties or is affected by changes in temperature and humidity. High temperature or humidity can easily cause it to deteriorate and damage its quality. Furthermore, it must be placed separately from oxidizing agents, strong alkalis, etc. If this compound encounters them, it may cause a violent chemical reaction, or even cause a dangerous accident. The storage place should be clearly marked to show that it is a dangerous chemical, so that everyone knows its risk and prevent accidental touch and misuse.
As for transportation, the transportation vehicle must have the corresponding qualifications. Drivers and escorts should also be professionally trained to be familiar with the characteristics of this compound and emergency treatment methods. During transportation, ensure that the container is stable and does not leak. In case of poor road conditions, it is necessary to drive slowly and steadily to prevent the container from being damaged due to bumps. If a leak unfortunately occurs, do not panic, and deal with it according to the plan as soon as possible. First evacuate the surrounding people and set up warning signs to prevent unrelated people from approaching. Then according to the leakage situation, take appropriate measures, such as covering and absorbing with sand and other substances, or neutralizing with specific chemicals.
In short, 2-%28bromomethyl%29-4-chloro-1-fluorobenzene in storage and transportation, it is necessary to strictly abide by the regulations and operate carefully to ensure safety and avoid danger.
2- (bromomethyl) -4-chloro-1-fluorobenzene impact on the environment
2-%28bromomethyl%29-4-chloro-1-fluorobenzene is 2 - (bromomethyl) - 4 - chloro - 1 - fluorobenzene, which has a significant impact on the environment.
It has the characteristics of halogenated aromatics and is chemically active. The presence of bromomethyl, chlorine and fluorine atoms makes it difficult to degrade in the environment. In the soil, it can remain for a long time, causing soil ecological disturbance. It may affect the structure and function of soil microbial communities, inhibit microbial activity, and then hinder material circulation and energy conversion in the soil. For example, the decomposition of organic matter in the soil is slowed down due to the suppression of microbial activity, and soil fertility is also affected.
In water bodies, 2- (bromomethyl) -4-chloro-1-fluorobenzene may dissolve or suspend, and disperse with water flow. It can cause water quality deterioration and affect the survival of aquatic organisms. It may be acutely toxic to aquatic animals such as fish, and interfere with their physiological activities such as respiration, feeding and reproduction. And or enriched through the food chain, small fish accidentally eat plankton containing this substance, and large fish eat small fish, resulting in increasing concentrations in organisms, endangering high-end organisms in the food chain, such as birds and mammals, and adversely affecting their health and population.
In the atmosphere, if 2- (bromomethyl) -4-chloro-1-fluorobenzene volatilizes, or participates in photochemical reactions, secondary pollutants such as ozone are generated, which will reduce the air quality and endanger human health and the ecological environment. And this material smells bad and volatilizes in the air, which also affects the surrounding air quality and residents' lives.
It has the characteristics of halogenated aromatics and is chemically active. The presence of bromomethyl, chlorine and fluorine atoms makes it difficult to degrade in the environment. In the soil, it can remain for a long time, causing soil ecological disturbance. It may affect the structure and function of soil microbial communities, inhibit microbial activity, and then hinder material circulation and energy conversion in the soil. For example, the decomposition of organic matter in the soil is slowed down due to the suppression of microbial activity, and soil fertility is also affected.
In water bodies, 2- (bromomethyl) -4-chloro-1-fluorobenzene may dissolve or suspend, and disperse with water flow. It can cause water quality deterioration and affect the survival of aquatic organisms. It may be acutely toxic to aquatic animals such as fish, and interfere with their physiological activities such as respiration, feeding and reproduction. And or enriched through the food chain, small fish accidentally eat plankton containing this substance, and large fish eat small fish, resulting in increasing concentrations in organisms, endangering high-end organisms in the food chain, such as birds and mammals, and adversely affecting their health and population.
In the atmosphere, if 2- (bromomethyl) -4-chloro-1-fluorobenzene volatilizes, or participates in photochemical reactions, secondary pollutants such as ozone are generated, which will reduce the air quality and endanger human health and the ecological environment. And this material smells bad and volatilizes in the air, which also affects the surrounding air quality and residents' lives.
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