Linshang Chemical
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2-Chloro-1,3,5-Trifluorobenzene
Linshang Chemical
|
HS Code |
580232 |
| Chemical Formula | C6H2ClF3 |
| Molar Mass | 166.53 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 107 - 109 °C |
| Melting Point | -46 °C |
| Density | 1.427 g/cm³ |
| Solubility In Water | Insoluble |
| Flash Point | 17 °C |
| Vapor Pressure | 2.36 kPa at 25 °C |
| Refractive Index | 1.444 (20 °C) |
As an accredited 2-Chloro-1,3,5-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500 - gram bottle of 2 - chloro - 1,3,5 - trifluorobenzene, well - sealed for safe storage. |
| Storage | 2 - chloro - 1,3,5 - trifluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and ignition points. It should be kept in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals to avoid potential chemical reactions. Ensure the storage location is dry to prevent hydrolysis. |
| Shipping | 2 - chloro - 1,3,5 - trifluorobenzene is shipped in specialized, well - sealed containers compliant with chemical transport regulations. These containers safeguard against leakage during transit to ensure safety and integrity of the chemical. |
Competitive 2-Chloro-1,3,5-Trifluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 2-Chloro-1,3,5-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-chloro-1,3,5-trifluorobenzene?
2-Chloro-1,3,5-trifluorobenzene is an important category of organic compounds. It has a wide range of uses and plays a pivotal role in the fields of medicine, pesticides and materials.
In the field of medicine, this compound is often a key intermediate. The synthesis of medicine depends on its unique chemical structure. Because it contains chlorine and fluorine atoms, it endows the molecule with special physical and chemical properties, such as enhanced fat solubility, making it easier to penetrate biological membranes, thereby enhancing the bioavailability of drugs. Chemists use it to build complex drug molecular structures and develop new therapeutic drugs, such as antibacterial and antiviral drugs, which are used to participate in the synthesis to achieve better pharmacological activity and therapeutic effects.
In the field of pesticides, 2-chloro-1,3,5-trifluorobenzene is also an important raw material. Due to the existence of fluorine atoms, the prepared pesticides are endowed with high efficiency, low toxicity and environmental friendliness. The pesticides synthesized on its basis have high selectivity and strong killing power to pests, can effectively prevent and control crop diseases and insect pests, ensure crop yield and quality, and have little residue in the environment. It has little impact on the ecological environment and meets the needs of the current green agriculture development.
In the field of materials, the role of this compound cannot be ignored. It can be used to synthesize special polymer materials, such as fluoropolymers. Such polymers have excellent heat resistance, chemical corrosion resistance and electrical properties. Applying it to high-end fields such as electronics and aerospace can meet the strict requirements of material properties in special environments. For example, in electronic components, fluoropolymers can be used as insulating materials, because of their good electrical properties, they can ensure the stable operation of electronic equipment; in the aerospace field, their heat and corrosion resistance properties can be used to manufacture aircraft engine parts, etc., to improve the performance and reliability of aircraft.
In the field of medicine, this compound is often a key intermediate. The synthesis of medicine depends on its unique chemical structure. Because it contains chlorine and fluorine atoms, it endows the molecule with special physical and chemical properties, such as enhanced fat solubility, making it easier to penetrate biological membranes, thereby enhancing the bioavailability of drugs. Chemists use it to build complex drug molecular structures and develop new therapeutic drugs, such as antibacterial and antiviral drugs, which are used to participate in the synthesis to achieve better pharmacological activity and therapeutic effects.
In the field of pesticides, 2-chloro-1,3,5-trifluorobenzene is also an important raw material. Due to the existence of fluorine atoms, the prepared pesticides are endowed with high efficiency, low toxicity and environmental friendliness. The pesticides synthesized on its basis have high selectivity and strong killing power to pests, can effectively prevent and control crop diseases and insect pests, ensure crop yield and quality, and have little residue in the environment. It has little impact on the ecological environment and meets the needs of the current green agriculture development.
In the field of materials, the role of this compound cannot be ignored. It can be used to synthesize special polymer materials, such as fluoropolymers. Such polymers have excellent heat resistance, chemical corrosion resistance and electrical properties. Applying it to high-end fields such as electronics and aerospace can meet the strict requirements of material properties in special environments. For example, in electronic components, fluoropolymers can be used as insulating materials, because of their good electrical properties, they can ensure the stable operation of electronic equipment; in the aerospace field, their heat and corrosion resistance properties can be used to manufacture aircraft engine parts, etc., to improve the performance and reliability of aircraft.
What are the physical properties of 2-chloro-1,3,5-trifluorobenzene?
2-Chloro-1,3,5-trifluorobenzene is one of the organic compounds. Its unique physical properties are listed below:
Looking at its properties, under normal temperature and pressure, 2-chloro-1,3,5-trifluorobenzene is a colorless and transparent liquid, clear and clear, visible as a mirror, without variegation and turbidity.
As for its boiling point, it is about 110-112 ° C. When the temperature gradually rises, the substance transforms from liquid to gaseous state, and the attractive force between molecules gradually weakens, breaking free from the shackles of the liquid phase and escaping into the air.
In terms of melting point, its value is about -39 ° C. If the ambient temperature drops to this value, 2-chloro-1,3,5-trifluorobenzene solidifies from liquid to solid, and the molecular arrangement tends to be orderly from disorder, forming a regular lattice structure.
In density, it is about 1.44 g/cm ³. This means that under the same volume, its mass is heavier than that of water (density is 1 g/cm ³). Placed in water, it must sink to the bottom, because its density is greater than that of water.
The vapor pressure of this substance exhibits a specific value at a specific temperature environment. Vapor pressure is the pressure of the gas phase when the gas phase and the liquid phase of the substance are in equilibrium. This pressure reflects the tendency of molecules to escape from the liquid phase. The higher the vapor pressure, the stronger the tendency of molecules to escape from the liquid phase. The vapor pressure of 2-chloro-1,3,5-trifluorobenzene will change accordingly with the rise and fall of the temperature. As the temperature increases, the vapor pressure also increases.
In terms of solubility, 2-chloro-1,3,5-trifluorobenzene is slightly soluble in water, but can be miscible with most organic solvents such as ethanol, ether, acetone, etc. Its solubility in water is poor, because water is a polar molecule, and the polarity of 2-chloro-1,3,5-trifluorobenzene is weak. According to the principle of "similar miscibility", the polarity is different, so it is difficult to dissolve in water. Organic solvents are mostly weakly polar or non-polar, and are similar to the polarity of 2-chloro-1,3,5-trifluorobenzene molecules, so they are miscible.
These are the physical properties of 2-chloro-1,3,5-trifluorobenzene, which are of important reference value in chemical research, industrial production and other fields.
Looking at its properties, under normal temperature and pressure, 2-chloro-1,3,5-trifluorobenzene is a colorless and transparent liquid, clear and clear, visible as a mirror, without variegation and turbidity.
As for its boiling point, it is about 110-112 ° C. When the temperature gradually rises, the substance transforms from liquid to gaseous state, and the attractive force between molecules gradually weakens, breaking free from the shackles of the liquid phase and escaping into the air.
In terms of melting point, its value is about -39 ° C. If the ambient temperature drops to this value, 2-chloro-1,3,5-trifluorobenzene solidifies from liquid to solid, and the molecular arrangement tends to be orderly from disorder, forming a regular lattice structure.
In density, it is about 1.44 g/cm ³. This means that under the same volume, its mass is heavier than that of water (density is 1 g/cm ³). Placed in water, it must sink to the bottom, because its density is greater than that of water.
The vapor pressure of this substance exhibits a specific value at a specific temperature environment. Vapor pressure is the pressure of the gas phase when the gas phase and the liquid phase of the substance are in equilibrium. This pressure reflects the tendency of molecules to escape from the liquid phase. The higher the vapor pressure, the stronger the tendency of molecules to escape from the liquid phase. The vapor pressure of 2-chloro-1,3,5-trifluorobenzene will change accordingly with the rise and fall of the temperature. As the temperature increases, the vapor pressure also increases.
In terms of solubility, 2-chloro-1,3,5-trifluorobenzene is slightly soluble in water, but can be miscible with most organic solvents such as ethanol, ether, acetone, etc. Its solubility in water is poor, because water is a polar molecule, and the polarity of 2-chloro-1,3,5-trifluorobenzene is weak. According to the principle of "similar miscibility", the polarity is different, so it is difficult to dissolve in water. Organic solvents are mostly weakly polar or non-polar, and are similar to the polarity of 2-chloro-1,3,5-trifluorobenzene molecules, so they are miscible.
These are the physical properties of 2-chloro-1,3,5-trifluorobenzene, which are of important reference value in chemical research, industrial production and other fields.
What are the chemical properties of 2-chloro-1,3,5-trifluorobenzene?
2-Chloro-1,3,5-trifluorobenzene is also an organic compound. Its chemical properties are well researched.
In this compound, the chlorine atom and the trifluorine atom coexist on a benzene ring. The fluorine atom has extremely high electronegativity, so it is above the benzene ring, which reduces the electron cloud density of the benzene ring. Although the chlorine atom also has an electron-sucking induction effect, it is weaker than the fluorine atom.
Due to the influence of fluorine and chlorine atoms, the electron cloud distribution of the benzene ring changes, resulting in its electrophilic substitution reaction activity different from that of the ordinary benzene ring. Usually, if the electrophilic reagent wants to attack this benzene ring, it is more difficult than attacking the benzene ring, and the
In the nucleophilic substitution reaction, 2-chloro-1,3,5-trifluorobenzene also has a unique performance. The chlorine atom on the benzene ring enhances the carbon positive electricity of the chlorine atom due to the electron-absorbing effect of the ortho-position and the para-position fluorine atom, so it is easier to be replaced by the attack of the nucleophilic reagent.
Furthermore, 2-chloro-1,3,5-trifluorobenzene has considerable chemical stability. The carbon-fluorine bond formed by the fluorine atom has a high energy, and more energy is required to break this bond. This stability has an important impact on specific chemical reactions and applications.
Its physical properties are also related to its chemical properties. Due to its fluorine, chlorine and other halogen atoms, the molecule has a certain polarity, and its solubility in organic solvents may be different from that of non-polar compounds. And its physical parameters such as boiling point and melting point are also affected by intermolecular forces, such as dipole-dipole forces.
In summary, the existence of fluorine and chlorine atoms on the 2-chloro-1,3,5-trifluorobenzene ring has unique chemical properties and has special applications and reactions in organic synthesis and other fields.
In this compound, the chlorine atom and the trifluorine atom coexist on a benzene ring. The fluorine atom has extremely high electronegativity, so it is above the benzene ring, which reduces the electron cloud density of the benzene ring. Although the chlorine atom also has an electron-sucking induction effect, it is weaker than the fluorine atom.
Due to the influence of fluorine and chlorine atoms, the electron cloud distribution of the benzene ring changes, resulting in its electrophilic substitution reaction activity different from that of the ordinary benzene ring. Usually, if the electrophilic reagent wants to attack this benzene ring, it is more difficult than attacking the benzene ring, and the
In the nucleophilic substitution reaction, 2-chloro-1,3,5-trifluorobenzene also has a unique performance. The chlorine atom on the benzene ring enhances the carbon positive electricity of the chlorine atom due to the electron-absorbing effect of the ortho-position and the para-position fluorine atom, so it is easier to be replaced by the attack of the nucleophilic reagent.
Furthermore, 2-chloro-1,3,5-trifluorobenzene has considerable chemical stability. The carbon-fluorine bond formed by the fluorine atom has a high energy, and more energy is required to break this bond. This stability has an important impact on specific chemical reactions and applications.
Its physical properties are also related to its chemical properties. Due to its fluorine, chlorine and other halogen atoms, the molecule has a certain polarity, and its solubility in organic solvents may be different from that of non-polar compounds. And its physical parameters such as boiling point and melting point are also affected by intermolecular forces, such as dipole-dipole forces.
In summary, the existence of fluorine and chlorine atoms on the 2-chloro-1,3,5-trifluorobenzene ring has unique chemical properties and has special applications and reactions in organic synthesis and other fields.
What is the preparation method of 2-chloro-1,3,5-trifluorobenzene?
2-Chloro-1,3,5-trifluorobenzene is also an organic compound. The method of its preparation is not detailed in the ancient book "Tiangong Kaiwu", but today's chemical classics and research can obtain the method of its preparation.
One method is to use 1,3,5-trifluorobenzene as the starting material to react with the chlorine source. Chlorine gas is often used as the chlorine source. Under suitable reaction conditions, such as at a specific temperature, pressure and catalyst, chlorine gas reacts with 1,3,5-trifluorobenzene.
The temperature of the reaction may be controlled within a certain range. If the temperature is too low, the reaction rate will be slow and time-consuming; if the temperature is too high, side reactions may occur, resulting in impure products. Generally speaking, it can be controlled between tens of degrees Celsius and hundreds of degrees Celsius. The specific value depends on the specific conditions of the reaction and the catalyst used.
The catalyst used is also critical. Lewis acid catalysts, such as aluminum trichloride and ferric chloride, are often used. Such catalysts can promote the reaction, making it easier for chlorine atoms to replace hydrogen atoms on the benzene ring.
When reacting, it is necessary to pay attention to the purity and dryness of the reaction system. If the system contains impurities or moisture, it may affect the progress of the reaction, resulting in a decrease in the yield of the product or the production of other by-products.
Another method may be obtained from other compounds containing chlorine and fluorine through a multi-step reaction. For example, the benzene ring compound containing a specific substituent is first prepared, and then the chlorine atom and fluorine atom are introduced through a series of reactions such as removal and substitution to form 2-chloro-1,3,5-trifluorobenzene. However, this multi-step reaction method has many steps, and the reaction conditions of each step need to be carefully controlled to ensure the purity and yield of the product.
The method of preparing 2-chloro-1,3,5-trifluorobenzene varies depending on the raw materials used and the reaction conditions, but it is necessary to fine-tune the reaction parameters to achieve the purpose of efficient preparation and high purity products.
One method is to use 1,3,5-trifluorobenzene as the starting material to react with the chlorine source. Chlorine gas is often used as the chlorine source. Under suitable reaction conditions, such as at a specific temperature, pressure and catalyst, chlorine gas reacts with 1,3,5-trifluorobenzene.
The temperature of the reaction may be controlled within a certain range. If the temperature is too low, the reaction rate will be slow and time-consuming; if the temperature is too high, side reactions may occur, resulting in impure products. Generally speaking, it can be controlled between tens of degrees Celsius and hundreds of degrees Celsius. The specific value depends on the specific conditions of the reaction and the catalyst used.
The catalyst used is also critical. Lewis acid catalysts, such as aluminum trichloride and ferric chloride, are often used. Such catalysts can promote the reaction, making it easier for chlorine atoms to replace hydrogen atoms on the benzene ring.
When reacting, it is necessary to pay attention to the purity and dryness of the reaction system. If the system contains impurities or moisture, it may affect the progress of the reaction, resulting in a decrease in the yield of the product or the production of other by-products.
Another method may be obtained from other compounds containing chlorine and fluorine through a multi-step reaction. For example, the benzene ring compound containing a specific substituent is first prepared, and then the chlorine atom and fluorine atom are introduced through a series of reactions such as removal and substitution to form 2-chloro-1,3,5-trifluorobenzene. However, this multi-step reaction method has many steps, and the reaction conditions of each step need to be carefully controlled to ensure the purity and yield of the product.
The method of preparing 2-chloro-1,3,5-trifluorobenzene varies depending on the raw materials used and the reaction conditions, but it is necessary to fine-tune the reaction parameters to achieve the purpose of efficient preparation and high purity products.
What are the precautions for using 2-chloro-1,3,5-trifluorobenzene?
2-Chloro-1,3,5-trifluorobenzene is a raw material for chemical use in engineering and research. When using it, be sure to pay attention to the following things:
First, it is toxic and irritating. Contact with the body, or cause skin red itching, eye burning, if inhaled, harm and exhalation, cough, stuffiness, and even dizziness. When doing this, you must wear protective equipment, such as gloves, goggles, and anti-virus masks, and in a well-ventilated place, avoid skin and eye contact, and avoid inhaling its gas.
Times, 2-chloro-1,3,5-trifluorobenzene flammable equipment, in case of open flame, high heat energy explosion. When in use, keep away from fire and heat sources, avoid sun exposure and high temperature, and use explosion-proof electrical appliances and equipment. During operation, prevent static accumulation, and avoid cremation and disaster.
In addition, its chemical activity is easy to react with other things. When using, know in detail its anti-nature with other chemical products, and avoid contact with ingredients, such as strong oxygen agents and strong alkalis. Mixing, mixing, or causing strong reactions, leading to dangerous things. Before use, it is appropriate to have a small test, clear the anti-strips and production, and after confirming safety, it will be operated in a large manner.
Repeat, when storing 2-chloro-1,3,5-trifluorobenzene, select an adapter, such as a glass bottle or a special plastic drum, which is dense and leak-proof. Store in yin, dry, and common places, protected from direct light and temperature changes. And standard name, danger, day, etc., it will be managed and recognized.
At the end of the day, waste at the end of use must comply with environmental laws and regulations. If it is not arranged at will, it should be handed over to a special office, according to the schedule, and the pollution-free ring.
First, it is toxic and irritating. Contact with the body, or cause skin red itching, eye burning, if inhaled, harm and exhalation, cough, stuffiness, and even dizziness. When doing this, you must wear protective equipment, such as gloves, goggles, and anti-virus masks, and in a well-ventilated place, avoid skin and eye contact, and avoid inhaling its gas.
Times, 2-chloro-1,3,5-trifluorobenzene flammable equipment, in case of open flame, high heat energy explosion. When in use, keep away from fire and heat sources, avoid sun exposure and high temperature, and use explosion-proof electrical appliances and equipment. During operation, prevent static accumulation, and avoid cremation and disaster.
In addition, its chemical activity is easy to react with other things. When using, know in detail its anti-nature with other chemical products, and avoid contact with ingredients, such as strong oxygen agents and strong alkalis. Mixing, mixing, or causing strong reactions, leading to dangerous things. Before use, it is appropriate to have a small test, clear the anti-strips and production, and after confirming safety, it will be operated in a large manner.
Repeat, when storing 2-chloro-1,3,5-trifluorobenzene, select an adapter, such as a glass bottle or a special plastic drum, which is dense and leak-proof. Store in yin, dry, and common places, protected from direct light and temperature changes. And standard name, danger, day, etc., it will be managed and recognized.
At the end of the day, waste at the end of use must comply with environmental laws and regulations. If it is not arranged at will, it should be handed over to a special office, according to the schedule, and the pollution-free ring.
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