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2-Chloro-1-(3-Ethoxy-4-Nitrophenoxy)-4-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
934594 |
| Chemical Formula | C15H11ClF3NO4 |
| Molecular Weight | 363.701 |
As an accredited 2-Chloro-1-(3-Ethoxy-4-Nitrophenoxy)-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 2 - chloro - 1 - (3 - ethoxy - 4 - nitrophenoxy) - 4 - (trifluoromethyl)benzene in sealed chemical drums. |
| Storage | 2 - chloro - 1 - (3 - ethoxy - 4 - nitrophenoxy)-4 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to decomposition or chemical reactions. |
| Shipping | 2 - chloro - 1 - (3 - ethoxy - 4 - nitrophenoxy) - 4 - (trifluoromethyl)benzene is shipped in accordance with chemical transport regulations. Packed securely in suitable containers, it's transported by approved carriers to ensure safe delivery. |
Competitive 2-Chloro-1-(3-Ethoxy-4-Nitrophenoxy)-4-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-1-(3-Ethoxy-4-Nitrophenoxy)-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 2-chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene?
2-Chloro-1 - (3-ethoxy-4-nitrophenoxy) -4 - (trifluoromethyl) benzene is widely used in various chemical and scientific fields.
One is that it can be a key intermediate in the process of pesticide creation. Due to its unique chemical structure, many active groups can be introduced through specific reactions to build efficient and selective pesticide molecules. If skillfully chemically transformed, insecticides with strong toxic effects on specific pests or fungicides with good inhibitory effects on certain plant diseases can be prepared. The chlorine atom, trifluoromethyl and phenoxy groups in its structure work synergistically to endow the final product with a suitable balance of fat solubility and water solubility, so that it can effectively penetrate the surface of pests or the cell wall of plant pathogens, and then exert biological activity.
Second, it also has potential value in the path of pharmaceutical research and development. It can be used as a starting material and modified by multi-step reaction to synthesize compounds with specific pharmacological activities. Its special substituent combination may interact with specific targets in the body, such as binding with the activity check points of certain enzymes to regulate the function of enzymes. Based on this, innovative drugs for the treatment of specific diseases may be developed.
Third, in the field of materials science, it can be used to prepare special functional materials. Because it contains trifluoromethyl, it can endow the material with unique physical and chemical properties, such as enhancing the corrosion resistance and weather resistance of the material. If it is introduced into the structure of polymer materials, it can prepare coatings and engineering plastics with excellent performance, which have considerable application prospects in aerospace, automobile manufacturing and other fields.
In summary, 2-chloro-1 - (3-ethoxy-4-nitrophenoxy) -4 - (trifluoromethyl) benzene is an important chemical raw material in many fields such as chemical industry, medicine and materials, and is of key significance to promote technological progress and innovation in various fields.
One is that it can be a key intermediate in the process of pesticide creation. Due to its unique chemical structure, many active groups can be introduced through specific reactions to build efficient and selective pesticide molecules. If skillfully chemically transformed, insecticides with strong toxic effects on specific pests or fungicides with good inhibitory effects on certain plant diseases can be prepared. The chlorine atom, trifluoromethyl and phenoxy groups in its structure work synergistically to endow the final product with a suitable balance of fat solubility and water solubility, so that it can effectively penetrate the surface of pests or the cell wall of plant pathogens, and then exert biological activity.
Second, it also has potential value in the path of pharmaceutical research and development. It can be used as a starting material and modified by multi-step reaction to synthesize compounds with specific pharmacological activities. Its special substituent combination may interact with specific targets in the body, such as binding with the activity check points of certain enzymes to regulate the function of enzymes. Based on this, innovative drugs for the treatment of specific diseases may be developed.
Third, in the field of materials science, it can be used to prepare special functional materials. Because it contains trifluoromethyl, it can endow the material with unique physical and chemical properties, such as enhancing the corrosion resistance and weather resistance of the material. If it is introduced into the structure of polymer materials, it can prepare coatings and engineering plastics with excellent performance, which have considerable application prospects in aerospace, automobile manufacturing and other fields.
In summary, 2-chloro-1 - (3-ethoxy-4-nitrophenoxy) -4 - (trifluoromethyl) benzene is an important chemical raw material in many fields such as chemical industry, medicine and materials, and is of key significance to promote technological progress and innovation in various fields.
What are the synthesis methods of 2-chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene
Nowadays, there are various methods for the synthesis of 2-chloro-1 - (3-ethoxy-4-nitrophenoxy) -4 - (trifluoromethyl) benzene.
One is to take 3-ethoxy-4-nitrophenol first and react it with a halogen-containing reagent to obtain a halogen. This halogen is then reacted with a reagent containing a 2-chloro-4 - (trifluoromethyl) phenoxy group structure under suitable reaction conditions, such as in the presence of a base. Nucleophilic substitution occurs. The choice of base is very critical, such as potassium carbonate, sodium carbonate, etc., in an organic solvent, heating and stirring to make the two fully react to obtain the target product.
Second, 2-chloro-4- (trifluoromethyl) phenol can also be prepared first, converted into phenolic salts, and then reacted with 3-ethoxy-4-nitrohalobenzene. This reaction requires attention to the reaction temperature, the ratio of reactants, and the control of reaction time. Too high or too low temperature may affect the yield and selectivity of the reaction.
Furthermore, other active intermediates can also be considered as starting materials, and the structure of the target molecule can be gradually constructed through multi-step reactions. For example, the benzene ring is first modified by specific substitution, introducing ethoxy, nitro, trifluoromethyl and other groups, and then through halogenation, etherification and other reactions, and finally the synthesis of 2-chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene is achieved. Each step of the reaction needs to be carefully regulated, and the optimization of the reaction conditions should be paid attention to to to improve the purity and yield of the product.
One is to take 3-ethoxy-4-nitrophenol first and react it with a halogen-containing reagent to obtain a halogen. This halogen is then reacted with a reagent containing a 2-chloro-4 - (trifluoromethyl) phenoxy group structure under suitable reaction conditions, such as in the presence of a base. Nucleophilic substitution occurs. The choice of base is very critical, such as potassium carbonate, sodium carbonate, etc., in an organic solvent, heating and stirring to make the two fully react to obtain the target product.
Second, 2-chloro-4- (trifluoromethyl) phenol can also be prepared first, converted into phenolic salts, and then reacted with 3-ethoxy-4-nitrohalobenzene. This reaction requires attention to the reaction temperature, the ratio of reactants, and the control of reaction time. Too high or too low temperature may affect the yield and selectivity of the reaction.
Furthermore, other active intermediates can also be considered as starting materials, and the structure of the target molecule can be gradually constructed through multi-step reactions. For example, the benzene ring is first modified by specific substitution, introducing ethoxy, nitro, trifluoromethyl and other groups, and then through halogenation, etherification and other reactions, and finally the synthesis of 2-chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene is achieved. Each step of the reaction needs to be carefully regulated, and the optimization of the reaction conditions should be paid attention to to to improve the purity and yield of the product.
What are the physical properties of 2-chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene
2-Chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene, which is an organic compound. Looking at its physical properties, it may be solid at room temperature and pressure, but the exact state also depends on the specific environmental conditions.
When it comes to the melting point, the intermolecular force and the regularity of the structure of this compound are all affected. There are chlorine atoms, trifluoromethyl groups, nitro groups and other functional groups in its molecules. Due to the electronic and spatial effects of these groups, the intermolecular force is complicated. For example, the nitro group is a strong electron-absorbing group, or the intermolecular force is enhanced, resulting in an increase in the melting point.
In terms of boiling point, the molecular weight is relatively large, and the functional groups contained in it enhance the intermolecular force. For example, ethoxy can participate in the intermolecular hydrogen bonding, or increase the boiling point. In addition, the existence of trifluoromethyl group also contributes to the intermolecular force due to its high electronegativity.
In terms of solubility, in organic solvents, according to the principle of similar miscibility, this compound contains benzene ring and many organic functional groups, or is easily soluble in non-polar or weakly polar organic solvents, such as toluene, dichloromethane, etc. However, due to the existence of polar functional groups such as nitro and ethoxy, in solvents with slightly stronger polarity, such as ethanol, there may be a certain solubility. In water, due to the relatively prominent non-polar characteristics of the overall structure, the solubility may be extremely low.
In addition, its density is higher than that of water, because the molecular structure contains chlorine, fluorine and other elements with relatively large atomic mass, or the density of the compound is higher than that of water. Appearance may be colorless to light yellow solid or liquid, odor may vary depending on specific purity and impurity conditions, pure or odor of special organic compounds.
When it comes to the melting point, the intermolecular force and the regularity of the structure of this compound are all affected. There are chlorine atoms, trifluoromethyl groups, nitro groups and other functional groups in its molecules. Due to the electronic and spatial effects of these groups, the intermolecular force is complicated. For example, the nitro group is a strong electron-absorbing group, or the intermolecular force is enhanced, resulting in an increase in the melting point.
In terms of boiling point, the molecular weight is relatively large, and the functional groups contained in it enhance the intermolecular force. For example, ethoxy can participate in the intermolecular hydrogen bonding, or increase the boiling point. In addition, the existence of trifluoromethyl group also contributes to the intermolecular force due to its high electronegativity.
In terms of solubility, in organic solvents, according to the principle of similar miscibility, this compound contains benzene ring and many organic functional groups, or is easily soluble in non-polar or weakly polar organic solvents, such as toluene, dichloromethane, etc. However, due to the existence of polar functional groups such as nitro and ethoxy, in solvents with slightly stronger polarity, such as ethanol, there may be a certain solubility. In water, due to the relatively prominent non-polar characteristics of the overall structure, the solubility may be extremely low.
In addition, its density is higher than that of water, because the molecular structure contains chlorine, fluorine and other elements with relatively large atomic mass, or the density of the compound is higher than that of water. Appearance may be colorless to light yellow solid or liquid, odor may vary depending on specific purity and impurity conditions, pure or odor of special organic compounds.
What are the chemical properties of 2-chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene
2-Chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene, an organic compound. Its chemical properties are unique and it is formed by the interaction of many functional groups.
First of all, the halogen atom, that is, the chlorine atom in it, endows this compound with activity. Halogen atoms often have nucleophilic substitution reaction activity. When encountering nucleophilic reagents, chlorine atoms are easily replaced. For example, under suitable conditions, nucleophilic reagents such as alkoxides and amines can react with the positions of chlorine atoms to form new compounds. This is a commonly used method in organic synthesis.
Furthermore, the benzene ring is structurally stable, but it can also carry out specific reactions. Due to its conjugated system, electrophilic substitution reactions can occur, such as nitrification, halogenation, sulfonation, etc. However, due to the presence of various substituents on the benzene ring, the activity and selectivity of these reactions are affected. In this compound, the benzene ring has been connected with chlorine atoms, trifluoromethyl groups, and phenoxy groups containing ethoxy and nitro groups, and these substituents will have a localization effect on the position of subsequent electrophilic substitution reactions.
Trifluoromethyl is a strong electron-absorbing group, which will reduce the electron cloud density of the benzene ring and weaken the activity of the electrophilic substitution reaction of the benzene ring, but also make the ortho and para-electron cloud densities relatively low, which in turn affects the offensive position of the electrophilic reagents and makes the reaction more
The ethoxy group in 3-ethoxy-4-nitrophenoxy group is the power supply group, which can increase the electron cloud density of the benzene ring and have a certain effect on the activity of the benzene ring; the nitro group is a strong electron-absorbing group, which significantly reduces the electron cloud density of the benzene ring. The two work together to have a complex effect on the reactivity and selectivity of the benzene ring.
In addition, the ether bonds in the molecule are relatively stable, but under certain conditions, such as strong acid or high temperature, a fracture reaction may occur to generate corresponding phenols and halogenated hydrocarbons.
This compound is rich in chemical properties due to its diverse functional groups, mutual influence, and potential application value in organic synthesis, medicinal chemistry, and other fields. It can be used as an intermediate for the synthesis of more complex compounds.
First of all, the halogen atom, that is, the chlorine atom in it, endows this compound with activity. Halogen atoms often have nucleophilic substitution reaction activity. When encountering nucleophilic reagents, chlorine atoms are easily replaced. For example, under suitable conditions, nucleophilic reagents such as alkoxides and amines can react with the positions of chlorine atoms to form new compounds. This is a commonly used method in organic synthesis.
Furthermore, the benzene ring is structurally stable, but it can also carry out specific reactions. Due to its conjugated system, electrophilic substitution reactions can occur, such as nitrification, halogenation, sulfonation, etc. However, due to the presence of various substituents on the benzene ring, the activity and selectivity of these reactions are affected. In this compound, the benzene ring has been connected with chlorine atoms, trifluoromethyl groups, and phenoxy groups containing ethoxy and nitro groups, and these substituents will have a localization effect on the position of subsequent electrophilic substitution reactions.
Trifluoromethyl is a strong electron-absorbing group, which will reduce the electron cloud density of the benzene ring and weaken the activity of the electrophilic substitution reaction of the benzene ring, but also make the ortho and para-electron cloud densities relatively low, which in turn affects the offensive position of the electrophilic reagents and makes the reaction more
The ethoxy group in 3-ethoxy-4-nitrophenoxy group is the power supply group, which can increase the electron cloud density of the benzene ring and have a certain effect on the activity of the benzene ring; the nitro group is a strong electron-absorbing group, which significantly reduces the electron cloud density of the benzene ring. The two work together to have a complex effect on the reactivity and selectivity of the benzene ring.
In addition, the ether bonds in the molecule are relatively stable, but under certain conditions, such as strong acid or high temperature, a fracture reaction may occur to generate corresponding phenols and halogenated hydrocarbons.
This compound is rich in chemical properties due to its diverse functional groups, mutual influence, and potential application value in organic synthesis, medicinal chemistry, and other fields. It can be used as an intermediate for the synthesis of more complex compounds.
What is the price range of 2-chloro-1- (3-ethoxy-4-nitrophenoxy) -4- (trifluoromethyl) benzene in the market?
I think this 2 - chloro - 1 - (3 - ethoxy - 4 - nitrophenoxy) - 4 - (trifluoromethyl) benzene is an organic compound. However, it is difficult to determine the market price range. The market price often changes due to many reasons.
First, the cost of production has a great impact. The price of raw materials may vary depending on the origin, season, supply and demand. If raw materials are scarce, the price will rise, the cost of this compound will also increase, and the price will be higher.
Second, the difficulty of preparation is also the key. If the synthesis steps are cumbersome, special reagents and conditions are required, and the process is complicated, the production cost will be high, and the market price will be high.
Third, the supply and demand relationship in the market determines the price. If the demand for this product is strong and the supply is limited, the price will increase; conversely, if the supply exceeds the demand, the price may drop.
Fourth, the differences in manufacturers and brands also lead to different prices. Well-known manufacturers may set prices differently from others due to quality control, reputation, etc.
Therefore, in order to know the exact price range of this compound, it is necessary to carefully observe the raw material market, production process, supply and demand situation, and manufacturer pricing strategies and many other factors. It is difficult to determine the price range.
First, the cost of production has a great impact. The price of raw materials may vary depending on the origin, season, supply and demand. If raw materials are scarce, the price will rise, the cost of this compound will also increase, and the price will be higher.
Second, the difficulty of preparation is also the key. If the synthesis steps are cumbersome, special reagents and conditions are required, and the process is complicated, the production cost will be high, and the market price will be high.
Third, the supply and demand relationship in the market determines the price. If the demand for this product is strong and the supply is limited, the price will increase; conversely, if the supply exceeds the demand, the price may drop.
Fourth, the differences in manufacturers and brands also lead to different prices. Well-known manufacturers may set prices differently from others due to quality control, reputation, etc.
Therefore, in order to know the exact price range of this compound, it is necessary to carefully observe the raw material market, production process, supply and demand situation, and manufacturer pricing strategies and many other factors. It is difficult to determine the price range.
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