Linshang Chemical
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2-Chloro-1,4-Dihydroxybenzene
Linshang Chemical
|
HS Code |
135273 |
| Name | 2-Chloro-1,4-Dihydroxybenzene |
| Molecular Formula | C6H5ClO2 |
| Molar Mass | 144.555 g/mol |
| Appearance | Solid (likely white or off - white) |
| Solubility In Water | Low solubility (phenolic compounds have limited water solubility due to non - polar benzene ring) |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether (due to its organic nature) |
As an accredited 2-Chloro-1,4-Dihydroxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 2 - chloro - 1,4 - dihydroxybenzene in 500 - gram sealed containers for safe storage. |
| Storage | 2 - chloro - 1,4 - dihydroxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and evaporation. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. |
| Shipping | 2 - chloro - 1,4 - dihydroxybenzene should be shipped in well - sealed, corrosion - resistant containers. Ensure compliance with hazardous chemical shipping regulations. Ship in a cool, dry environment away from heat and ignition sources. |
Competitive 2-Chloro-1,4-Dihydroxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-1,4-Dihydroxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-chloro-1,4-dihydroxybenzene?
2-Chloro-1,4-dihydroxybenzene, this is an organic compound. Its chemical properties are interesting and have unique reactivity.
First talk about the properties of its phenolic hydroxyl group. Because it contains phenolic hydroxyl groups, it is weakly acidic and can react with bases. Just like the general properties of phenols, it can react with bases such as sodium hydroxide to form corresponding phenolic salts and water. This is because the electron cloud of oxygen atoms in the phenolic hydroxyl group conjugates with the phenyl ring, resulting in enhanced hydrogen-oxygen bond polarity, and hydrogen atoms are easy to leave in the form of protons.
Furthermore, the properties of its halogen atoms cannot be ignored. The presence of chlorine atoms enables the compound to participate in nucleophilic substitution reactions. In the typical reaction of halogenated hydrocarbons, nucleophiles can attack the carbon atoms attached to chlorine, and the chlorine atoms leave to form new compounds. For example, when reacted with sodium alcohol, corresponding ether compounds can be formed.
In addition, the benzene ring of the compound is also active. The benzene ring is affected by phenolic hydroxyl groups, and the electron cloud density increases, making it more prone to electrophilic substitution reactions. Electrophilic substitution reactions such as halogenation, nitrification, and sulfonation can occur at specific positions on the benzene ring. Hydroxyl groups are ortho-and para-sites, guiding electrophilic reagents to mainly attack the ortho-and para-sites of hydroxyl groups.
At the same time, due to the presence of phenolic hydroxyl groups, the compound is easily oxidized. It can oxidize slowly in air, and the color And under the action of oxidants, more complex oxidation reactions can occur to form quinones and other oxidation products.
In summary, the chemical properties of 2-chloro-1,4-dihydroxybenzene are rich and diverse, which are determined by the interaction of functional groups it contains, and have important application value in organic synthesis and other fields.
First talk about the properties of its phenolic hydroxyl group. Because it contains phenolic hydroxyl groups, it is weakly acidic and can react with bases. Just like the general properties of phenols, it can react with bases such as sodium hydroxide to form corresponding phenolic salts and water. This is because the electron cloud of oxygen atoms in the phenolic hydroxyl group conjugates with the phenyl ring, resulting in enhanced hydrogen-oxygen bond polarity, and hydrogen atoms are easy to leave in the form of protons.
Furthermore, the properties of its halogen atoms cannot be ignored. The presence of chlorine atoms enables the compound to participate in nucleophilic substitution reactions. In the typical reaction of halogenated hydrocarbons, nucleophiles can attack the carbon atoms attached to chlorine, and the chlorine atoms leave to form new compounds. For example, when reacted with sodium alcohol, corresponding ether compounds can be formed.
In addition, the benzene ring of the compound is also active. The benzene ring is affected by phenolic hydroxyl groups, and the electron cloud density increases, making it more prone to electrophilic substitution reactions. Electrophilic substitution reactions such as halogenation, nitrification, and sulfonation can occur at specific positions on the benzene ring. Hydroxyl groups are ortho-and para-sites, guiding electrophilic reagents to mainly attack the ortho-and para-sites of hydroxyl groups.
At the same time, due to the presence of phenolic hydroxyl groups, the compound is easily oxidized. It can oxidize slowly in air, and the color And under the action of oxidants, more complex oxidation reactions can occur to form quinones and other oxidation products.
In summary, the chemical properties of 2-chloro-1,4-dihydroxybenzene are rich and diverse, which are determined by the interaction of functional groups it contains, and have important application value in organic synthesis and other fields.
What are the physical properties of 2-chloro-1,4-dihydroxybenzene?
2-Chloro-1,4-dihydroxybenzene is one of the organic compounds. Its physical properties are quite important and have applications in chemical, pharmaceutical and other fields.
First of all, its appearance is often white to light yellow crystalline powder, which is conducive to observation and use. Looking at the color and morphology, its initial appearance can be known.
times and melting point, about a specific temperature range, this property helps to distinguish and purify. Due to the slight difference in the melting point of the substance with different purity, the purity geometry can be determined by the measurement of the melting point.
In addition, solubility, in some organic solvents, such as ethanol, acetone, etc., has a certain solubility. This property allows it to better participate in the reaction or make a specific dosage form during chemical reactions and preparation. In water, the solubility is relatively limited, but it is not completely insoluble, which is related to the hydroxyl groups and chlorine atoms contained in the molecular structure. Hydroxyl groups are hydrophilic, and the presence of chlorine atoms affects their solubility.
In terms of its density, although there is no exact value of the common saying, the size of the density is related to its distribution and mixing in different media, which is also meaningful in actual production and experimental operations.
Volatility, under normal temperature and pressure, the volatility is weak, which makes it relatively stable during storage and use, and is not easy to be lost due to volatilization or cause environmental problems. The physical properties of 2-chloro-1,4-dihydroxybenzene play a key role in many aspects, laying the foundation for its application in different fields and providing an important basis for the research and use of this substance.
First of all, its appearance is often white to light yellow crystalline powder, which is conducive to observation and use. Looking at the color and morphology, its initial appearance can be known.
times and melting point, about a specific temperature range, this property helps to distinguish and purify. Due to the slight difference in the melting point of the substance with different purity, the purity geometry can be determined by the measurement of the melting point.
In addition, solubility, in some organic solvents, such as ethanol, acetone, etc., has a certain solubility. This property allows it to better participate in the reaction or make a specific dosage form during chemical reactions and preparation. In water, the solubility is relatively limited, but it is not completely insoluble, which is related to the hydroxyl groups and chlorine atoms contained in the molecular structure. Hydroxyl groups are hydrophilic, and the presence of chlorine atoms affects their solubility.
In terms of its density, although there is no exact value of the common saying, the size of the density is related to its distribution and mixing in different media, which is also meaningful in actual production and experimental operations.
Volatility, under normal temperature and pressure, the volatility is weak, which makes it relatively stable during storage and use, and is not easy to be lost due to volatilization or cause environmental problems. The physical properties of 2-chloro-1,4-dihydroxybenzene play a key role in many aspects, laying the foundation for its application in different fields and providing an important basis for the research and use of this substance.
What are the main uses of 2-chloro-1,4-dihydroxybenzene?
2-Chloro-1,4-dihydroxybenzene, this is an organic compound. It has many main uses and is often used as a synthetic raw material in the chemical industry to prepare various fine chemicals.
In the dye industry, it can be used as a key intermediate to help synthesize colorful dyes. Because its molecular structure contains hydroxyl groups and chlorine atoms, it gives it unique chemical activity. It can connect different groups by chemical reaction to produce dyes with various colors and properties, adding color to the textile, printing and dyeing industries.
In the field of pharmaceutical chemistry, 2-chloro-1,4-dihydroxybenzene is also of great significance. It can be used as a starting material or intermediate for the synthesis of drugs. Its special structure can participate in specific reactions, build a molecular skeleton with biological activity, and lay the foundation for the development of drugs for the treatment of various diseases, such as antibacterial, anti-inflammatory and other drugs.
In addition, in the field of materials science, it may be used to prepare functional materials. With its chemical properties, or can participate in polymerization reactions, polymer materials with special properties are formed, such as smart materials that respond to light, electricity, heat and other stimuli, and have potential applications in sensors, electronic devices, etc.
In short, 2-chloro-1,4-dihydroxybenzene has shown important uses in many fields such as chemicals, dyes, medicine, materials, etc., and promotes the development and progress of various industries.
In the dye industry, it can be used as a key intermediate to help synthesize colorful dyes. Because its molecular structure contains hydroxyl groups and chlorine atoms, it gives it unique chemical activity. It can connect different groups by chemical reaction to produce dyes with various colors and properties, adding color to the textile, printing and dyeing industries.
In the field of pharmaceutical chemistry, 2-chloro-1,4-dihydroxybenzene is also of great significance. It can be used as a starting material or intermediate for the synthesis of drugs. Its special structure can participate in specific reactions, build a molecular skeleton with biological activity, and lay the foundation for the development of drugs for the treatment of various diseases, such as antibacterial, anti-inflammatory and other drugs.
In addition, in the field of materials science, it may be used to prepare functional materials. With its chemical properties, or can participate in polymerization reactions, polymer materials with special properties are formed, such as smart materials that respond to light, electricity, heat and other stimuli, and have potential applications in sensors, electronic devices, etc.
In short, 2-chloro-1,4-dihydroxybenzene has shown important uses in many fields such as chemicals, dyes, medicine, materials, etc., and promotes the development and progress of various industries.
What are the synthesis methods of 2-chloro-1,4-dihydroxybenzene?
To prepare 2-chloro-1,4-dihydroxybenzene, there are various methods. One can be started with hydroquinone. Hydroquinone can be halogenated by chlorine atoms. Usually, appropriate halogenating agents, such as thionyl chloride and phosphorus oxychloride, are used to react with hydroquinone under suitable reaction conditions. When reacting, pay attention to factors such as temperature and solvent. If the temperature is too high, it may cause side reactions and lead to impure products; if the temperature is too low, the reaction will be delayed. Choose a suitable solvent, such as dichloromethane, chloroform and other halogenated hydrocarbons, which can help the reactants to be miscible and promote the smooth progress of the reaction.
Second, you can start from the corresponding phenol ether. The chlorine-containing phenol ether is first prepared, and then the target product is obtained by the step of deprotecting the group. To prepare the chlorophenol ether, the Williamson ether synthesis method of phenol and halogenated hydrocarbons under the action of alkali can be used. Potassium carbonate, sodium hydroxide, etc. can be selected for the base. After obtaining the chlorophenol ether, hydrolysis under acidic or basic conditions removes the protective group, and then obtains 2-chloro-1,4-dihydroxybenzene.
Or consider using benzene as the starting material and preparing it through a multi-step reaction. First, the benzene is sulfonated, and the sulfonic acid group is introduced to obtain benzenesulfonic acid. After the chlorination reaction, the chlorine atom is introduced at an appropriate position. Then the sulfonic acid group is converted into hydroxyl group by alkali fusion method, and the hydroxyl group is introduced into another position. After a series of reaction operations, the final product is 2-chloro-1,4-dihydroxybenzene. However, there are many steps in this route, and each step needs to be carefully controlled to ensure high yield and purity.
Second, you can start from the corresponding phenol ether. The chlorine-containing phenol ether is first prepared, and then the target product is obtained by the step of deprotecting the group. To prepare the chlorophenol ether, the Williamson ether synthesis method of phenol and halogenated hydrocarbons under the action of alkali can be used. Potassium carbonate, sodium hydroxide, etc. can be selected for the base. After obtaining the chlorophenol ether, hydrolysis under acidic or basic conditions removes the protective group, and then obtains 2-chloro-1,4-dihydroxybenzene.
Or consider using benzene as the starting material and preparing it through a multi-step reaction. First, the benzene is sulfonated, and the sulfonic acid group is introduced to obtain benzenesulfonic acid. After the chlorination reaction, the chlorine atom is introduced at an appropriate position. Then the sulfonic acid group is converted into hydroxyl group by alkali fusion method, and the hydroxyl group is introduced into another position. After a series of reaction operations, the final product is 2-chloro-1,4-dihydroxybenzene. However, there are many steps in this route, and each step needs to be carefully controlled to ensure high yield and purity.
What are the precautions for 2-chloro-1,4-dihydroxybenzene during storage and transportation?
For 2-chloro-1,4-dihydroxybenzene, there are several urgent precautions during storage and transportation.
First, it is related to the temperature and humidity of storage. This substance should be stored in a cool and dry place. Cover its properties in the environment of excessive temperature and humidity, or change. If it is at high temperature, it may cause its chemical structure to be unstable, or cause reactions such as decomposition; if the humidity is too high, it may absorb moisture, which may affect its purity and quality. Therefore, it is necessary to choose a storage place with constant temperature, dry and ventilated to ensure its stability.
Second, when it comes to packaging. Packaging must be tight and suitable. Commonly used packaging materials should have good sealing and corrosion resistance. If the packaging is not good, the outside air, moisture, etc. are easy to invade and damage its quality. If it is packed in a special glass bottle or a plastic container with a protective inner layer, it can effectively block the interference of external factors.
Third, when transporting, pay attention to vibration and collision. 2-Chloro-1,4-dihydroxybenzene under severe vibration or collision, or cause damage to the package, and may also deteriorate due to internal structure disturbance. When the transportation vehicle is running smoothly and loading, it should be properly fixed with cushioning materials to reduce the damage of vibration and collision.
Fourth, to isolate fire sources and oxidants. This substance may have certain chemical activity, and it is easy to cause combustion and other hazards when exposed to fire sources; contact with oxidants is more likely to trigger violent chemical reactions, endangering safety. Therefore, during storage and transportation, it should be kept away from fire sources and oxidants.
Fifth, the label logo should not be ignored. On the package, its name, nature, danger warning and other information should be clearly marked. In this way, during storage and transportation, the relevant personnel can see at a glance, and can properly handle and protect it according to its characteristics, so as to keep the safety of the whole process.
First, it is related to the temperature and humidity of storage. This substance should be stored in a cool and dry place. Cover its properties in the environment of excessive temperature and humidity, or change. If it is at high temperature, it may cause its chemical structure to be unstable, or cause reactions such as decomposition; if the humidity is too high, it may absorb moisture, which may affect its purity and quality. Therefore, it is necessary to choose a storage place with constant temperature, dry and ventilated to ensure its stability.
Second, when it comes to packaging. Packaging must be tight and suitable. Commonly used packaging materials should have good sealing and corrosion resistance. If the packaging is not good, the outside air, moisture, etc. are easy to invade and damage its quality. If it is packed in a special glass bottle or a plastic container with a protective inner layer, it can effectively block the interference of external factors.
Third, when transporting, pay attention to vibration and collision. 2-Chloro-1,4-dihydroxybenzene under severe vibration or collision, or cause damage to the package, and may also deteriorate due to internal structure disturbance. When the transportation vehicle is running smoothly and loading, it should be properly fixed with cushioning materials to reduce the damage of vibration and collision.
Fourth, to isolate fire sources and oxidants. This substance may have certain chemical activity, and it is easy to cause combustion and other hazards when exposed to fire sources; contact with oxidants is more likely to trigger violent chemical reactions, endangering safety. Therefore, during storage and transportation, it should be kept away from fire sources and oxidants.
Fifth, the label logo should not be ignored. On the package, its name, nature, danger warning and other information should be clearly marked. In this way, during storage and transportation, the relevant personnel can see at a glance, and can properly handle and protect it according to its characteristics, so as to keep the safety of the whole process.
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