Linshang Chemical
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2-Chloro-1-Fluoro-3-Nitrobenzene
Linshang Chemical
|
HS Code |
793370 |
| Chemical Formula | C6H3ClFNO2 |
| Appearance | Yellow to light brown liquid or solid |
| Boiling Point | 210 - 212 °C |
| Melting Point | 27 - 31 °C |
| Density | 1.48 g/cm³ |
| Solubility In Water | Insoluble |
| Vapor Pressure | Low |
| Flash Point | 88 °C |
| Refractive Index | 1.556 |
As an accredited 2-Chloro-1-Fluoro-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2 - chloro - 1 - fluoro - 3 - nitrobenzene packaged in a sealed, corrosion - resistant bottle. |
| Storage | 2 - chloro - 1 - fluoro - 3 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and bases to prevent chemical reactions. Label the storage container clearly with relevant hazard information. |
| Shipping | 2 - chloro - 1 - fluoro - 3 - nitrobenzene is a hazardous chemical. Shipping requires compliance with strict regulations. It must be properly packaged in suitable containers, labeled clearly, and transported by carriers authorized for such chemicals. |
Competitive 2-Chloro-1-Fluoro-3-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-1-Fluoro-3-Nitrobenzene in China?
As a trusted 2-Chloro-1-Fluoro-3-Nitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-1-Fluoro-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-chloro-1-fluoro-3-nitrobenzene?
2-Chloro-1-fluoro-3-nitrobenzene is a crucial intermediate in organic synthesis. It has a wide range of uses and plays a key role in many fields.
In the field of pharmaceutical synthesis, it is often an important starting material for the preparation of specific drugs. Due to its unique chemical structure, molecular structures with specific pharmacological activities can be constructed through specific chemical reactions. For example, through carefully designed reaction steps, other functional groups can be introduced to shape drug molecules that combine with disease targets and help develop new drugs for specific diseases.
also plays an indispensable role in the creation of pesticides. Through chemical modification and derivatization, pesticide varieties with high insecticidal, bactericidal or herbicidal properties can be developed. Due to the characteristics endowed by its structure, pesticides can precisely act on specific physiological processes of pests, improve control effects, and reduce adverse effects on the environment.
In the field of materials science, 2-chloro-1-fluoro-3-nitrobenzene can be used as a precursor for the synthesis of special functional materials. For example, polymer materials with unique electrical, optical or mechanical properties can be prepared through polymerization or cross-linking with other compounds, which can be used in electronic devices, optical coatings and other fields.
Furthermore, in the dye industry, it can provide a basic structure for the synthesis of new dyes. By skillfully adjusting its substituents and reaction paths, dyes with bright colors and excellent fastness can be obtained to meet the diverse needs of textile, printing and dyeing industries.
In summary, 2-chloro-1-fluoro-3-nitrobenzene has shown irreplaceable uses in many industrial fields such as medicine, pesticides, materials and dyes, providing important chemical support for the development of various industries.
In the field of pharmaceutical synthesis, it is often an important starting material for the preparation of specific drugs. Due to its unique chemical structure, molecular structures with specific pharmacological activities can be constructed through specific chemical reactions. For example, through carefully designed reaction steps, other functional groups can be introduced to shape drug molecules that combine with disease targets and help develop new drugs for specific diseases.
also plays an indispensable role in the creation of pesticides. Through chemical modification and derivatization, pesticide varieties with high insecticidal, bactericidal or herbicidal properties can be developed. Due to the characteristics endowed by its structure, pesticides can precisely act on specific physiological processes of pests, improve control effects, and reduce adverse effects on the environment.
In the field of materials science, 2-chloro-1-fluoro-3-nitrobenzene can be used as a precursor for the synthesis of special functional materials. For example, polymer materials with unique electrical, optical or mechanical properties can be prepared through polymerization or cross-linking with other compounds, which can be used in electronic devices, optical coatings and other fields.
Furthermore, in the dye industry, it can provide a basic structure for the synthesis of new dyes. By skillfully adjusting its substituents and reaction paths, dyes with bright colors and excellent fastness can be obtained to meet the diverse needs of textile, printing and dyeing industries.
In summary, 2-chloro-1-fluoro-3-nitrobenzene has shown irreplaceable uses in many industrial fields such as medicine, pesticides, materials and dyes, providing important chemical support for the development of various industries.
What are the physical properties of 2-chloro-1-fluoro-3-nitrobenzene?
2-Chloro-1-fluoro-3-nitrobenzene is a kind of organic compound. Its physical properties are as follows:
Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid. This color and character are quite common among organic compounds, but it also varies slightly due to changes in purity and external conditions.
As for the smell, it often has a special pungent smell. This smell is pungent and easy to be sensed by the sense of smell. Because it contains chlorine, fluorine, nitro and other functional groups, it causes a unique molecular structure, so the smell is significant.
When it comes to boiling point, it is about a certain temperature range, which is determined by the intermolecular force. The dipole-dipole interaction between its molecules, coupled with the influence of chlorine, fluorine and nitro groups, makes the boiling point specific. However, the exact value also varies slightly due to different experimental conditions and instruments. The melting point of
is also in a specific temperature range. The arrangement and interaction of molecules determine its melting point characteristics. When the temperature drops below the melting point, the compound will change from liquid to solid state, and the lattice structure will gradually become orderly.
In terms of solubility, 2-chloro-1-fluoro-3-nitrobenzene has a certain solubility in organic solvents such as ethanol, ether, etc. This is due to the principle of similarity dissolution, and its organic structure is similar to the intermolecular force of organic solvents, so it is soluble. However, in water, the solubility is very small, because the polarity of its molecules is quite different from that of water, and it is difficult to miscible with each other.
The density is higher than that of water, and when placed in water, it will sink to the bottom. Due to the molecular mass and structure, its unit volume mass is greater than that of water.
In addition, the vapor pressure of 2-chloro-1-fluoro-3-nitrobenzene varies at different temperatures. When the temperature increases, the vapor pressure increases, and more molecules are able to escape the liquid surface and distribute more in the gas phase. This physical property is of great significance for chemical production, storage and transportation.
Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid. This color and character are quite common among organic compounds, but it also varies slightly due to changes in purity and external conditions.
As for the smell, it often has a special pungent smell. This smell is pungent and easy to be sensed by the sense of smell. Because it contains chlorine, fluorine, nitro and other functional groups, it causes a unique molecular structure, so the smell is significant.
When it comes to boiling point, it is about a certain temperature range, which is determined by the intermolecular force. The dipole-dipole interaction between its molecules, coupled with the influence of chlorine, fluorine and nitro groups, makes the boiling point specific. However, the exact value also varies slightly due to different experimental conditions and instruments. The melting point of
is also in a specific temperature range. The arrangement and interaction of molecules determine its melting point characteristics. When the temperature drops below the melting point, the compound will change from liquid to solid state, and the lattice structure will gradually become orderly.
In terms of solubility, 2-chloro-1-fluoro-3-nitrobenzene has a certain solubility in organic solvents such as ethanol, ether, etc. This is due to the principle of similarity dissolution, and its organic structure is similar to the intermolecular force of organic solvents, so it is soluble. However, in water, the solubility is very small, because the polarity of its molecules is quite different from that of water, and it is difficult to miscible with each other.
The density is higher than that of water, and when placed in water, it will sink to the bottom. Due to the molecular mass and structure, its unit volume mass is greater than that of water.
In addition, the vapor pressure of 2-chloro-1-fluoro-3-nitrobenzene varies at different temperatures. When the temperature increases, the vapor pressure increases, and more molecules are able to escape the liquid surface and distribute more in the gas phase. This physical property is of great significance for chemical production, storage and transportation.
Is 2-chloro-1-fluoro-3-nitrobenzene chemically stable?
The chemical stability of 2-chloro-1-fluoro-3-nitrobenzene is an interesting topic. This compound contains chlorine, fluorine, nitro and other functional groups. Each functional group has unique chemical activities, which affect its stability under the influence of each other.
Although both chlorine and fluorine atoms are halogen elements, their electronegativity and atomic radius are different. The electronegativity of fluorine is extremely strong, so that the carbon-fluorine bond energy is quite high and it is not easy to break; the electronegativity of chlorine is slightly weaker, and the carbon-chlorine bond is relatively active. The two coexist on the benzene ring, which affects the distribution of electron clouds in the benzene ring.
The nitro group is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring, make the benzene ring more vulnerable to nucleophilic attack, and enhance the activity of adjacent and para-hydrogen atoms.
In terms of overall stability, under normal conditions, 2-chloro-1-fluoro-3-nitrobenzene is still stable. When encountering high temperature, strong acid-base or specific catalyst, its chemical activity will be revealed. For example, in high temperature and strong alkali environment, chlorine atoms or fluorine atoms may undergo substitution reactions; nitro groups can also be reduced under specific reduction conditions.
The stability of 2-chloro-1-fluoro-3-nitrobenzene is not absolute, and it will change with the change of chemical conditions in the environment. Although it is relatively stable under normal conditions, in special chemical scenarios, the activity or chemical reaction of each functional group occurs.
Although both chlorine and fluorine atoms are halogen elements, their electronegativity and atomic radius are different. The electronegativity of fluorine is extremely strong, so that the carbon-fluorine bond energy is quite high and it is not easy to break; the electronegativity of chlorine is slightly weaker, and the carbon-chlorine bond is relatively active. The two coexist on the benzene ring, which affects the distribution of electron clouds in the benzene ring.
The nitro group is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring, make the benzene ring more vulnerable to nucleophilic attack, and enhance the activity of adjacent and para-hydrogen atoms.
In terms of overall stability, under normal conditions, 2-chloro-1-fluoro-3-nitrobenzene is still stable. When encountering high temperature, strong acid-base or specific catalyst, its chemical activity will be revealed. For example, in high temperature and strong alkali environment, chlorine atoms or fluorine atoms may undergo substitution reactions; nitro groups can also be reduced under specific reduction conditions.
The stability of 2-chloro-1-fluoro-3-nitrobenzene is not absolute, and it will change with the change of chemical conditions in the environment. Although it is relatively stable under normal conditions, in special chemical scenarios, the activity or chemical reaction of each functional group occurs.
What is the preparation method of 2-chloro-1-fluoro-3-nitrobenzene?
The preparation method of 2-chloro-1-fluoro-3-nitrobenzene is an important topic in the field of chemical synthesis. Its preparation often follows a specific organic synthesis path.
A common method uses benzene as the starting material. The benzene is first nitrified to introduce the benzene ring into the nitro group. In this step, the mixed acid of concentrated nitric acid and concentrated sulfuric acid is often used as the nitrifying reagent. Under suitable temperature conditions, benzene and the mixed acid undergo an electrophilic substitution reaction, and the hydrogen atom on the benzene ring is replaced by the nitro group to form nitrobenzene.
Then, the nitrobenzene is halogenated. In the halogenation process, suitable halogenating reagents and reaction conditions need to be selected. To introduce chlorine atoms and fluorine atoms, specific reagents containing chlorine and fluorine can be selected respectively. For example, when introducing chlorine atoms, chlorine gas and suitable catalysts can be used to replace hydrogen atoms at specific positions on the benzene ring under light or heating conditions; when introducing fluorine atoms, in view of the reactivity of fluorine, special fluorination reagents, such as fluorine-containing salts, are often selected and reacted under suitable solvents and reaction conditions to precisely introduce fluorine atoms at designated positions in the benzene ring. After such a series of reactions, 2-chloro-1-fluoro-3-nitrobenzene can be finally obtained.
During the preparation process, the control of the conditions of each reaction step is extremely critical. Such as reaction temperature, reaction time, reagent dosage ratio, etc., all have a significant impact on the yield and purity of the reaction products. Only by fine regulation of each reaction parameter can high-efficiency and high-quality 2-chloro-1-fluoro-3-nitrobenzene preparation be achieved.
A common method uses benzene as the starting material. The benzene is first nitrified to introduce the benzene ring into the nitro group. In this step, the mixed acid of concentrated nitric acid and concentrated sulfuric acid is often used as the nitrifying reagent. Under suitable temperature conditions, benzene and the mixed acid undergo an electrophilic substitution reaction, and the hydrogen atom on the benzene ring is replaced by the nitro group to form nitrobenzene.
Then, the nitrobenzene is halogenated. In the halogenation process, suitable halogenating reagents and reaction conditions need to be selected. To introduce chlorine atoms and fluorine atoms, specific reagents containing chlorine and fluorine can be selected respectively. For example, when introducing chlorine atoms, chlorine gas and suitable catalysts can be used to replace hydrogen atoms at specific positions on the benzene ring under light or heating conditions; when introducing fluorine atoms, in view of the reactivity of fluorine, special fluorination reagents, such as fluorine-containing salts, are often selected and reacted under suitable solvents and reaction conditions to precisely introduce fluorine atoms at designated positions in the benzene ring. After such a series of reactions, 2-chloro-1-fluoro-3-nitrobenzene can be finally obtained.
During the preparation process, the control of the conditions of each reaction step is extremely critical. Such as reaction temperature, reaction time, reagent dosage ratio, etc., all have a significant impact on the yield and purity of the reaction products. Only by fine regulation of each reaction parameter can high-efficiency and high-quality 2-chloro-1-fluoro-3-nitrobenzene preparation be achieved.
2-chloro-1-fluoro-3-nitrobenzene What are the precautions during storage and transportation?
2-Chloro-1-fluoro-3-nitrobenzene is one of the organic compounds. When storing and transporting, pay attention to many matters.
First words storage. This compound has certain chemical activity and potential danger, and should be stored in a cool, dry and well-ventilated place. Because it is more sensitive to heat and high temperature is prone to chemical reactions, it should be avoided from direct sunlight and heat sources. The temperature of the warehouse should be controlled within a suitable range to prevent the decomposition of substances or other accidents caused by excessive temperature. Furthermore, it should be stored separately from oxidants, reducing agents, alkalis and other substances. Due to its active chemical properties, contact with the above substances is prone to violent reactions, which can even lead to serious consequences such as fire and explosion. The storage place should also have corresponding anti-leakage measures. If there is any leakage, it can be collected and treated in time to avoid polluting the environment.
As for transportation. Before transportation, make sure that the packaging is complete and well sealed. Packaging materials need to be able to withstand general physical impact and chemical erosion to prevent material leakage due to package damage during transportation. Transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment for emergencies. During transportation, drivers should drive slowly to avoid bumps and sudden braking to prevent package damage. At the same time, transportation routes should try to avoid densely populated areas and environmentally sensitive areas. In case of leakage, the harm to people and the environment can be reduced. Transport personnel should also be familiar with the characteristics of the substance and emergency treatment methods, and be able to respond promptly and properly in case of emergencies.
First words storage. This compound has certain chemical activity and potential danger, and should be stored in a cool, dry and well-ventilated place. Because it is more sensitive to heat and high temperature is prone to chemical reactions, it should be avoided from direct sunlight and heat sources. The temperature of the warehouse should be controlled within a suitable range to prevent the decomposition of substances or other accidents caused by excessive temperature. Furthermore, it should be stored separately from oxidants, reducing agents, alkalis and other substances. Due to its active chemical properties, contact with the above substances is prone to violent reactions, which can even lead to serious consequences such as fire and explosion. The storage place should also have corresponding anti-leakage measures. If there is any leakage, it can be collected and treated in time to avoid polluting the environment.
As for transportation. Before transportation, make sure that the packaging is complete and well sealed. Packaging materials need to be able to withstand general physical impact and chemical erosion to prevent material leakage due to package damage during transportation. Transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment for emergencies. During transportation, drivers should drive slowly to avoid bumps and sudden braking to prevent package damage. At the same time, transportation routes should try to avoid densely populated areas and environmentally sensitive areas. In case of leakage, the harm to people and the environment can be reduced. Transport personnel should also be familiar with the characteristics of the substance and emergency treatment methods, and be able to respond promptly and properly in case of emergencies.
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