Linshang Chemical
PRODUCTS
2-Chloro-1-Fluoro-4-Iodobenzene
Linshang Chemical
|
HS Code |
149433 |
| Chemical Formula | C6H3ClFI |
| Molar Mass | 256.44 g/mol |
| Appearance | Typically a liquid (physical state may vary depending on conditions) |
| Solubility In Water | Low solubility, due to non - polar nature of benzene ring |
| Solubility In Organic Solvents | Good solubility in common organic solvents like ethanol, ether etc. |
As an accredited 2-Chloro-1-Fluoro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2 - chloro - 1 - fluoro - 4 - iodobenzene packaged in a sealed, chemical - resistant bottle. |
| Storage | 2 - chloro - 1 - fluoro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage and exposure to air and moisture, which could potentially lead to decomposition or unwanted reactions. Label the storage container clearly for easy identification. |
| Shipping | 2 - chloro - 1 - fluoro - 4 - iodobenzene is a chemical. Ship it in well - sealed, corrosion - resistant containers. Follow all hazardous materials regulations, ensuring proper labeling and handling to prevent spills and ensure safe transportation. |
Competitive 2-Chloro-1-Fluoro-4-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-1-Fluoro-4-Iodobenzene in China?
As a trusted 2-Chloro-1-Fluoro-4-Iodobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-1-Fluoro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-chloro-1-fluoro-4-iodobenzene?
2-Chloro-1-fluoro-4-iodobenzene is also an organic compound. It has a wide range of uses in the chemical industry and is often a key raw material for organic synthesis.
In the synthesis of medicine, this compound can be used as an important intermediate. Because it contains halogen atoms, it can introduce specific functional groups through chemical reactions, and then construct bioactive molecular structures to help create new drugs. For example, it can be used to synthesize drugs with antibacterial and antiviral effects, contributing to the development of medicine.
In the field of materials science, 2-chloro-1-fluoro-4-iodobenzene is also useful. After a specific polymerization reaction, it can be integrated into polymer materials, giving the material unique properties. Such as improving the thermal stability, mechanical properties or optical properties of the material to meet the needs of different fields for special materials.
Furthermore, in the synthesis of pesticides, it can be used as a starting material to prepare highly efficient and low-toxic pesticides through a series of reactions. With its halogen atom characteristics, the mechanism of action of pesticides is optimized, the control effect of pests and pathogens is improved, and it escorts agricultural production.
In addition, in the preparation of fine chemical products, 2-chloro-1-fluoro-4-iodobenzene can be used to synthesize various fine chemicals, such as fragrances, dye intermediates, etc. Through ingenious organic synthesis routes, a variety of products are added to the fine chemical industry to meet people's pursuit of high-quality life.
In summary, although 2-chloro-1-fluoro-4-iodobenzene is an organic compound, it plays an indispensable and important role in many fields such as medicine, materials, pesticides and fine chemicals, and promotes the development and progress of various fields.
In the synthesis of medicine, this compound can be used as an important intermediate. Because it contains halogen atoms, it can introduce specific functional groups through chemical reactions, and then construct bioactive molecular structures to help create new drugs. For example, it can be used to synthesize drugs with antibacterial and antiviral effects, contributing to the development of medicine.
In the field of materials science, 2-chloro-1-fluoro-4-iodobenzene is also useful. After a specific polymerization reaction, it can be integrated into polymer materials, giving the material unique properties. Such as improving the thermal stability, mechanical properties or optical properties of the material to meet the needs of different fields for special materials.
Furthermore, in the synthesis of pesticides, it can be used as a starting material to prepare highly efficient and low-toxic pesticides through a series of reactions. With its halogen atom characteristics, the mechanism of action of pesticides is optimized, the control effect of pests and pathogens is improved, and it escorts agricultural production.
In addition, in the preparation of fine chemical products, 2-chloro-1-fluoro-4-iodobenzene can be used to synthesize various fine chemicals, such as fragrances, dye intermediates, etc. Through ingenious organic synthesis routes, a variety of products are added to the fine chemical industry to meet people's pursuit of high-quality life.
In summary, although 2-chloro-1-fluoro-4-iodobenzene is an organic compound, it plays an indispensable and important role in many fields such as medicine, materials, pesticides and fine chemicals, and promotes the development and progress of various fields.
What are the physical properties of 2-chloro-1-fluoro-4-iodobenzene?
2-Chloro-1-fluoro-4-iodobenzene is one of the organohalogenated aromatic hydrocarbons. Its physical properties are quite critical, and it has important uses in many fields such as chemical industry and medicine.
The first to bear the brunt is the melting point and boiling point. Due to the intermolecular force, the melting point of this compound is about [X] ° C, and the boiling point is about [X] ° C. The presence of chlorine, fluorine, and iodine atoms in the molecule results in changes in molecular polarity, which in turn affects the intermolecular force and affects the melting boiling point.
Furthermore, its solubility is observed. 2-Chloro-1-fluoro-4-iodobenzene is insoluble in water, but it is soluble in common organic solvents such as ethanol, ether, dichloromethane, etc. This difference in solubility is due to the non-polar characteristics of its molecules. It is difficult to form effective interactions with water molecules, but it can dissolve with organic solvent molecules by force such as van der Waals force.
As for density, the density of 2-chloro-1-fluoro-4-iodobenzene is greater than that of water. This is due to the large relative atomic weight of halogen atoms such as chlorine, fluorine, and iodine, which increases the molecular weight, resulting in a higher density than water. This property is of great significance when it involves experimental or industrial operations such as stratification.
In addition, 2-chloro-1-fluoro-4-iodobenzene is liquid at room temperature and pressure, and has a certain volatility. Its volatility is affected by factors such as temperature and pressure. When the temperature increases and the pressure decreases, the volatility will be enhanced.
Because of the halogen atoms in its molecules, it has a certain chemical activity and can participate in a variety of chemical reactions, such as nucleophilic substitution reactions, which are also closely related to its physical properties.
In conclusion, the physical properties of 2-chloro-1-fluoro-4-iodobenzene, such as melting point, solubility, density, and volatility, play a crucial role in its application and operation in chemical production and scientific research.
The first to bear the brunt is the melting point and boiling point. Due to the intermolecular force, the melting point of this compound is about [X] ° C, and the boiling point is about [X] ° C. The presence of chlorine, fluorine, and iodine atoms in the molecule results in changes in molecular polarity, which in turn affects the intermolecular force and affects the melting boiling point.
Furthermore, its solubility is observed. 2-Chloro-1-fluoro-4-iodobenzene is insoluble in water, but it is soluble in common organic solvents such as ethanol, ether, dichloromethane, etc. This difference in solubility is due to the non-polar characteristics of its molecules. It is difficult to form effective interactions with water molecules, but it can dissolve with organic solvent molecules by force such as van der Waals force.
As for density, the density of 2-chloro-1-fluoro-4-iodobenzene is greater than that of water. This is due to the large relative atomic weight of halogen atoms such as chlorine, fluorine, and iodine, which increases the molecular weight, resulting in a higher density than water. This property is of great significance when it involves experimental or industrial operations such as stratification.
In addition, 2-chloro-1-fluoro-4-iodobenzene is liquid at room temperature and pressure, and has a certain volatility. Its volatility is affected by factors such as temperature and pressure. When the temperature increases and the pressure decreases, the volatility will be enhanced.
Because of the halogen atoms in its molecules, it has a certain chemical activity and can participate in a variety of chemical reactions, such as nucleophilic substitution reactions, which are also closely related to its physical properties.
In conclusion, the physical properties of 2-chloro-1-fluoro-4-iodobenzene, such as melting point, solubility, density, and volatility, play a crucial role in its application and operation in chemical production and scientific research.
Is 2-chloro-1-fluoro-4-iodobenzene chemically stable?
The chemical properties of 2-chloro-1-fluoro-4-iodobenzene are stable at room temperature. In this compound, chlorine, fluorine, and iodine are all halogen atoms. The fluorine atom is extremely electronegative and has a strong electron-absorbing effect. The electron cloud density of the benzene ring decreases, which weakens the activity of the electrophilic substitution reaction.
Looking at its stability, the chemical bond between the halogen atom and the benzene ring is quite strong. Carbon-fluorine bond, due to the strong electronegativity of fluorine, the bond length and bond energy are large, and it is not easy to break. Although the bond energy of carbon-chlorine bonds and carbon-iodine bonds is slightly inferior to that of carbon-fluorine bonds, it is difficult to spontaneously dissociate under normal conditions.
The stability of this compound may also change under specific conditions. In case of high temperature, strong light or strong oxidizing agent or strong reducing agent, this compound may react. If the high temperature coexists with the catalyst, the halogen atom may be replaced by other groups. Taking the nucleophilic substitution reaction as an example, an appropriate nucleophilic reagent can attack the benzene ring and cause the halogen atom to leave.
And if it encounters an active metal, such as magnesium, in an anhydrous ether environment, or forms a Grignard reagent, this shows the active side of its chemical properties. Therefore, in general, 2-chloro-1-fluoro-4-iodobenzene is stable under conventional conditions, but in special situations, it can also exhibit a variety of chemical reactivity.
Looking at its stability, the chemical bond between the halogen atom and the benzene ring is quite strong. Carbon-fluorine bond, due to the strong electronegativity of fluorine, the bond length and bond energy are large, and it is not easy to break. Although the bond energy of carbon-chlorine bonds and carbon-iodine bonds is slightly inferior to that of carbon-fluorine bonds, it is difficult to spontaneously dissociate under normal conditions.
The stability of this compound may also change under specific conditions. In case of high temperature, strong light or strong oxidizing agent or strong reducing agent, this compound may react. If the high temperature coexists with the catalyst, the halogen atom may be replaced by other groups. Taking the nucleophilic substitution reaction as an example, an appropriate nucleophilic reagent can attack the benzene ring and cause the halogen atom to leave.
And if it encounters an active metal, such as magnesium, in an anhydrous ether environment, or forms a Grignard reagent, this shows the active side of its chemical properties. Therefore, in general, 2-chloro-1-fluoro-4-iodobenzene is stable under conventional conditions, but in special situations, it can also exhibit a variety of chemical reactivity.
What are 2-chloro-1-fluoro-4-iodobenzene synthesis methods?
To prepare 2-chloro-1-fluoro-4-iodobenzene, there are many methods, and there are several common methods.
First, 1-fluoro-4-iodobenzene is used as the starting material to react with chlorine-containing reagents. Commonly used ones such as N-chlorosuccinimide (NCS), in suitable solvents such as dichloromethane, under the action of light or initiator, chlorine atoms can replace hydrogen on the benzene ring to obtain the target product. This reaction condition is milder and has good selectivity. However, it is necessary to pay attention to the reaction process to prevent excessive chlorination.
Second, use 2-chloro-1-fluorobenzene as raw material to react with the iodine source. Usually, iodine element (I ³) can be selected, and an appropriate oxidizing agent such as hydrogen peroxide (H2O) or nitric acid (HNO <) can be assisted. The function of the oxidizing agent is to oxidize iodine ions to iodine positive ions, and then undergo electrophilic substitution reaction with the benzene ring to obtain 2-chloro-1-fluoro-4-iodobenzene. However, when using strong oxidizing agents, the reaction conditions need to be carefully controlled to prevent affecting the existing substituents on the benzene ring.
Third, it can be achieved by multi-step reaction. A suitable benzene ring precursor is prepared first, and an appropriate substituent is introduced, and then the structure of the target molecule is gradually constructed through a series of reactions such as halogenation and substitution. For example, benzene derivatives containing fluorine and chlorine are first synthesized, and then iodine atoms are introduced through a specific reaction. Although this approach has many steps, it can be fine-tuned according to the required reaction conditions and intermediate products to obtain higher yield and purity.
The above methods have advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider the availability of raw materials, the difficulty of reaction conditions, yield and purity, and choose the optimal method to achieve the purpose of efficient synthesis of 2-chloro-1-fluoro-4-iodobenzene.
First, 1-fluoro-4-iodobenzene is used as the starting material to react with chlorine-containing reagents. Commonly used ones such as N-chlorosuccinimide (NCS), in suitable solvents such as dichloromethane, under the action of light or initiator, chlorine atoms can replace hydrogen on the benzene ring to obtain the target product. This reaction condition is milder and has good selectivity. However, it is necessary to pay attention to the reaction process to prevent excessive chlorination.
Second, use 2-chloro-1-fluorobenzene as raw material to react with the iodine source. Usually, iodine element (I ³) can be selected, and an appropriate oxidizing agent such as hydrogen peroxide (H2O) or nitric acid (HNO <) can be assisted. The function of the oxidizing agent is to oxidize iodine ions to iodine positive ions, and then undergo electrophilic substitution reaction with the benzene ring to obtain 2-chloro-1-fluoro-4-iodobenzene. However, when using strong oxidizing agents, the reaction conditions need to be carefully controlled to prevent affecting the existing substituents on the benzene ring.
Third, it can be achieved by multi-step reaction. A suitable benzene ring precursor is prepared first, and an appropriate substituent is introduced, and then the structure of the target molecule is gradually constructed through a series of reactions such as halogenation and substitution. For example, benzene derivatives containing fluorine and chlorine are first synthesized, and then iodine atoms are introduced through a specific reaction. Although this approach has many steps, it can be fine-tuned according to the required reaction conditions and intermediate products to obtain higher yield and purity.
The above methods have advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider the availability of raw materials, the difficulty of reaction conditions, yield and purity, and choose the optimal method to achieve the purpose of efficient synthesis of 2-chloro-1-fluoro-4-iodobenzene.
What is the price range of 2-chloro-1-fluoro-4-iodobenzene in the market?
What is the price of 2-chloro-1-fluoro-4-iodobenzene in the city? The price in the market varies from time to time and from place to place. It is difficult to determine its price due to factors such as quality, supply and demand.
Looking at the past market conditions, if you look for chemical raw materials, the price of such fine chemicals is often related to the difficulty of preparation and the price of raw materials. If the preparation method is complex, if the materials used are thin, the price will be high; on the contrary, if the preparation is easy and the raw materials are sufficient, the price will be low.
In the past, in some chemical trading places, the price per gram of such compounds, if it is of ordinary purity, may range from tens to hundreds of dollars. However, if you want high purity, or special specifications, specially designed for experimental research, high-end industrial use, the price should be several times or even dozens of times higher.
In today's world, the chemical industry is changing, and the production of raw materials, trade regulations, and environmental protection policies all affect their prices. If the origin of raw materials changes, resulting in poor supply, prices will rise; and if trade ripples, tariffs will increase or decrease, which will also make prices move. As for environmental protection policies, production is restricted, and costs increase and prices rise.
is to know the exact price of 2-chloro-1-fluoro-4-iodobenzene, when consulting the chemical material supplier, depending on the current market conditions, to obtain its more accurate price.
Looking at the past market conditions, if you look for chemical raw materials, the price of such fine chemicals is often related to the difficulty of preparation and the price of raw materials. If the preparation method is complex, if the materials used are thin, the price will be high; on the contrary, if the preparation is easy and the raw materials are sufficient, the price will be low.
In the past, in some chemical trading places, the price per gram of such compounds, if it is of ordinary purity, may range from tens to hundreds of dollars. However, if you want high purity, or special specifications, specially designed for experimental research, high-end industrial use, the price should be several times or even dozens of times higher.
In today's world, the chemical industry is changing, and the production of raw materials, trade regulations, and environmental protection policies all affect their prices. If the origin of raw materials changes, resulting in poor supply, prices will rise; and if trade ripples, tariffs will increase or decrease, which will also make prices move. As for environmental protection policies, production is restricted, and costs increase and prices rise.
is to know the exact price of 2-chloro-1-fluoro-4-iodobenzene, when consulting the chemical material supplier, depending on the current market conditions, to obtain its more accurate price.
Scan to WhatsApp
