Linshang Chemical
PRODUCTS
2-Chloro-1-Iodo-4-Methoxybenzene
Linshang Chemical
|
HS Code |
986048 |
| Chemical Formula | C7H6ClIO |
| Molecular Weight | 270.48 |
| Appearance | Solid (Typical) |
| Melting Point | Data may vary, check literature |
| Boiling Point | Data may vary, check literature |
| Density | Data may vary, check literature |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
| Flash Point | Data may vary, check literature |
| Vapor Pressure | Data may vary, check literature |
| Stability | Stable under normal conditions, avoid strong oxidizing agents |
As an accredited 2-Chloro-1-Iodo-4-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 2 - chloro - 1 - iodo - 4 - methoxybenzene packaged in a sealed glass bottle. |
| Storage | 2 - Chloro - 1 - iodo - 4 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and incompatible substances. Keep it in a tightly sealed container, preferably made of corrosion - resistant material. Since it is a chemical, proper labeling is crucial to indicate its identity and potential hazards for safe handling. |
| Shipping | 2 - chloro - 1 - iodo - 4 - methoxybenzene is shipped in sealed, corrosion - resistant containers. It's transported under cool, dry conditions, following strict chemical safety regulations to prevent spills and ensure safe delivery. |
Competitive 2-Chloro-1-Iodo-4-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-1-Iodo-4-Methoxybenzene in China?
As a trusted 2-Chloro-1-Iodo-4-Methoxybenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-1-Iodo-4-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-chloro-1-iodo-4-methoxybenzene?
2-Chloro-1-iodine-4-methoxybenzene, an organic compound, has unique chemical properties and is of great research value.
First of all, the substitution reaction is discussed, because there are chlorine, iodine and methoxy groups attached to the benzene ring. Chlorine and iodine are both halogen atoms, and halogen atoms can be replaced under specific conditions. Taking nucleophilic substitution as an example, when encountering strong nucleophilic reagents, halogen atoms can be replaced by nucleophilic reagents. For example, in an alkaline environment, some nucleophilic reagents may attack the carbon atoms attached to halogen atoms, replacing halogen atoms and generating new organic compounds.
Looking at its redox properties, the oxygen atom in the methoxy group has a certain electronegativity, which can affect the electron cloud density of the benzene ring. The benzene ring can be oxidized under appropriate conditions, for example, under the action of strong oxidants, the benzene ring structure may be destroyed to form an oxygen-containing compound. The halogen atom can also participate in the redox reaction, and the halogen atom valence state may be changed.
In addition, the halogen atom of 2-chloro-1-iodine-4-methoxy benzene can also participate in the elimination reaction. Under the action of a suitable base, the halogen atom forms an unsaturated bond with the hydrogen atom on the adjacent carbon atom or dehalogenated hydrogen to form an olefin compound.
At the same time, the electron cloud density of the benzene ring of the compound changes due to the power supply effect of methoxy group, which makes the benzene ring more prone to electrophilic substitution reactions. Electrophilic reagents tend to attack the positions with higher electron cloud density on the benzene ring, and then generate various electrophilic substitution products.
In summary, 2-chloro-1-iodine-4-methoxybenzene is used in the field of organic synthesis. With its diverse chemical properties, it can be used as an important intermediate to participate in many organic reactions and be used to synthesize organic compounds with more complex structures.
First of all, the substitution reaction is discussed, because there are chlorine, iodine and methoxy groups attached to the benzene ring. Chlorine and iodine are both halogen atoms, and halogen atoms can be replaced under specific conditions. Taking nucleophilic substitution as an example, when encountering strong nucleophilic reagents, halogen atoms can be replaced by nucleophilic reagents. For example, in an alkaline environment, some nucleophilic reagents may attack the carbon atoms attached to halogen atoms, replacing halogen atoms and generating new organic compounds.
Looking at its redox properties, the oxygen atom in the methoxy group has a certain electronegativity, which can affect the electron cloud density of the benzene ring. The benzene ring can be oxidized under appropriate conditions, for example, under the action of strong oxidants, the benzene ring structure may be destroyed to form an oxygen-containing compound. The halogen atom can also participate in the redox reaction, and the halogen atom valence state may be changed.
In addition, the halogen atom of 2-chloro-1-iodine-4-methoxy benzene can also participate in the elimination reaction. Under the action of a suitable base, the halogen atom forms an unsaturated bond with the hydrogen atom on the adjacent carbon atom or dehalogenated hydrogen to form an olefin compound.
At the same time, the electron cloud density of the benzene ring of the compound changes due to the power supply effect of methoxy group, which makes the benzene ring more prone to electrophilic substitution reactions. Electrophilic reagents tend to attack the positions with higher electron cloud density on the benzene ring, and then generate various electrophilic substitution products.
In summary, 2-chloro-1-iodine-4-methoxybenzene is used in the field of organic synthesis. With its diverse chemical properties, it can be used as an important intermediate to participate in many organic reactions and be used to synthesize organic compounds with more complex structures.
What are the common synthetic methods of 2-chloro-1-iodo-4-methoxybenzene?
2-Chloro-1-iodine-4-methoxybenzene is also an organic compound. There are about three common synthesis methods.
One is to start with 4-methoxyaniline. Shilling 4-methoxyaniline is co-heated with hydrochloric acid and sodium nitrite to form diazonium salts. Following the action of potassium iodide with it, 1-iodine-4-methoxybenzene can be obtained. After adding chlorine gas or chlorine-containing reagents, under suitable conditions, 2-chloro-1-iodine-4-methoxybenzene can be obtained. During this process, the temperature of the diazotization reaction must be carefully controlled to prevent the decomposition of diazonium salts.
Second, 4-methoxyphenol is used as the starting material. First, an iodine substitution reagent, such as iodine, is used in combination with an oxidizing agent to iodinate the phenolic hydroxyl ortho-position to obtain 1-iodine-4-methoxyphenol. Then the product is reacted with a methylating reagent, such as dimethyl sulfate or iodomethane, under the catalysis of a base to form 1-iodine-4-methoxyanisole. Finally, the target product is obtained by chlorinating the phenyl ring with a chlorinated reagent, such as N-chlorosuccinimide (NCS), under suitable solvents and conditions. In this way, attention should be paid to the amount of base and reaction conditions in the methylation step to avoid excessive methylation or destruction of phenolic hydroxyl groups.
Third, use p-methoxy anisole as the initial material. First, use a chlorination reagent to chlorinate the phenyl ring to obtain 2-chloro-4-methoxy anisole. Then use an iodine substitution reagent, such as iodine, potassium iodide and an oxidant, to iodine a specific position on the phenyl ring, and finally obtain 2-chloro-1-iodine-4-methoxy benzene. In this process, the selective control of the chlorination and iodine substitution steps is crucial. When looking for the appropriate reaction conditions and the ratio of reagents, in order to increase the yield of the target product.
One is to start with 4-methoxyaniline. Shilling 4-methoxyaniline is co-heated with hydrochloric acid and sodium nitrite to form diazonium salts. Following the action of potassium iodide with it, 1-iodine-4-methoxybenzene can be obtained. After adding chlorine gas or chlorine-containing reagents, under suitable conditions, 2-chloro-1-iodine-4-methoxybenzene can be obtained. During this process, the temperature of the diazotization reaction must be carefully controlled to prevent the decomposition of diazonium salts.
Second, 4-methoxyphenol is used as the starting material. First, an iodine substitution reagent, such as iodine, is used in combination with an oxidizing agent to iodinate the phenolic hydroxyl ortho-position to obtain 1-iodine-4-methoxyphenol. Then the product is reacted with a methylating reagent, such as dimethyl sulfate or iodomethane, under the catalysis of a base to form 1-iodine-4-methoxyanisole. Finally, the target product is obtained by chlorinating the phenyl ring with a chlorinated reagent, such as N-chlorosuccinimide (NCS), under suitable solvents and conditions. In this way, attention should be paid to the amount of base and reaction conditions in the methylation step to avoid excessive methylation or destruction of phenolic hydroxyl groups.
Third, use p-methoxy anisole as the initial material. First, use a chlorination reagent to chlorinate the phenyl ring to obtain 2-chloro-4-methoxy anisole. Then use an iodine substitution reagent, such as iodine, potassium iodide and an oxidant, to iodine a specific position on the phenyl ring, and finally obtain 2-chloro-1-iodine-4-methoxy benzene. In this process, the selective control of the chlorination and iodine substitution steps is crucial. When looking for the appropriate reaction conditions and the ratio of reagents, in order to increase the yield of the target product.
2-chloro-1-iodo-4-methoxybenzene in what areas?
2-Chloro-1-iodine-4-methoxybenzene is useful in many fields. In the field of medicinal chemistry, it can be a key intermediate for the creation of new drugs. Due to its unique structure, it can introduce different functional groups through various chemical reactions, and then synthesize compounds with specific biological activities. For example, chlorine or iodine atoms can be replaced by other groups by nucleophilic substitution reactions to prepare drugs that have curative effects on specific diseases, or to develop antibacterial, antiviral and other drugs.
In materials science, it is also used. Or can participate in the preparation of materials with special photoelectric properties. Using it as the starting material, the conjugated system is constructed by organic synthesis, and it is expected to obtain materials that can be used in optoelectronic devices such as organic Light Emitting Diode (OLED) and solar cells. The presence of halogen atoms and methoxy groups in its structure can affect the electron cloud distribution and energy level structure of the material, thereby imparting specific optoelectronic properties to the material.
Furthermore, in the field of organic synthesis chemistry, this compound is an important class of substrates. Chemists can use various reactions, such as palladium-catalyzed coupling reactions, to use the activity of their halogen atoms to connect with other organic molecules to build more complex organic skeleton structures for the synthesis of natural products, fine chemicals, etc., to expand the types and functions of organic compounds, providing an important foundation for the development of organic synthetic chemistry.
In materials science, it is also used. Or can participate in the preparation of materials with special photoelectric properties. Using it as the starting material, the conjugated system is constructed by organic synthesis, and it is expected to obtain materials that can be used in optoelectronic devices such as organic Light Emitting Diode (OLED) and solar cells. The presence of halogen atoms and methoxy groups in its structure can affect the electron cloud distribution and energy level structure of the material, thereby imparting specific optoelectronic properties to the material.
Furthermore, in the field of organic synthesis chemistry, this compound is an important class of substrates. Chemists can use various reactions, such as palladium-catalyzed coupling reactions, to use the activity of their halogen atoms to connect with other organic molecules to build more complex organic skeleton structures for the synthesis of natural products, fine chemicals, etc., to expand the types and functions of organic compounds, providing an important foundation for the development of organic synthetic chemistry.
What are the physical properties of 2-chloro-1-iodo-4-methoxybenzene?
2-Chloro-1-iodine-4-methoxybenzene, this is an organic compound. Its physical properties are quite important and are involved in various fields of chemistry.
Looking at its properties, under room temperature and pressure, 2-chloro-1-iodine-4-methoxybenzene is mostly in a solid state. Due to the interaction between molecules, the interaction between atoms makes the molecules closely arranged, so they are in a solid state.
The melting point has been determined by many experiments to be about a certain temperature range. The melting point is an inherent property of a substance and is closely related to the molecular structure. In this compound, chlorine, iodine, methoxy and other groups interact with each other, resulting in a specific state of intermolecular forces, which in turn determines the melting point.
The boiling point is also a key physical property. Under specific pressure conditions, 2-chloro-1-iodine-4-methoxybenzene boils at a certain temperature. The boiling point is related to the intermolecular forces and the relative molecular mass. The relative molecular mass of the compound depends on the type and quantity of atoms, and there are effects such as van der Waals forces between molecules, which comprehensively determine the boiling point.
In terms of solubility, 2-chloro-1-iodine-4-methoxybenzene has a certain solubility in organic solvents, such as common ether, dichloromethane, etc. Due to the principle of "similar miscibility", the compound is an organic molecule with a similar structure to an organic solvent, and a certain interaction can be formed between molecules to promote dissolution. In water, its solubility is poor, and water is a polar molecule. It has a large structural difference and weak interaction with the organic compound, so it is difficult to dissolve.
In addition, the color state of 2-chloro-1-iodine-4-methoxybenzene is usually colorless to light yellow. The formation of this color is due to the absorption and reflection characteristics of light by the molecular structure, and the process of electron transition in the molecule causes it to exhibit a specific color.
In summary, the physical properties of 2-chloro-1-iodine-4-methoxybenzene, such as solid state, specific melting point, boiling point, solubility and color state, are determined by its molecular structure, and are of great significance in organic synthesis, pharmaceutical chemistry and other fields. It is related to reaction conditions, separation and purification, and many other operations.
Looking at its properties, under room temperature and pressure, 2-chloro-1-iodine-4-methoxybenzene is mostly in a solid state. Due to the interaction between molecules, the interaction between atoms makes the molecules closely arranged, so they are in a solid state.
The melting point has been determined by many experiments to be about a certain temperature range. The melting point is an inherent property of a substance and is closely related to the molecular structure. In this compound, chlorine, iodine, methoxy and other groups interact with each other, resulting in a specific state of intermolecular forces, which in turn determines the melting point.
The boiling point is also a key physical property. Under specific pressure conditions, 2-chloro-1-iodine-4-methoxybenzene boils at a certain temperature. The boiling point is related to the intermolecular forces and the relative molecular mass. The relative molecular mass of the compound depends on the type and quantity of atoms, and there are effects such as van der Waals forces between molecules, which comprehensively determine the boiling point.
In terms of solubility, 2-chloro-1-iodine-4-methoxybenzene has a certain solubility in organic solvents, such as common ether, dichloromethane, etc. Due to the principle of "similar miscibility", the compound is an organic molecule with a similar structure to an organic solvent, and a certain interaction can be formed between molecules to promote dissolution. In water, its solubility is poor, and water is a polar molecule. It has a large structural difference and weak interaction with the organic compound, so it is difficult to dissolve.
In addition, the color state of 2-chloro-1-iodine-4-methoxybenzene is usually colorless to light yellow. The formation of this color is due to the absorption and reflection characteristics of light by the molecular structure, and the process of electron transition in the molecule causes it to exhibit a specific color.
In summary, the physical properties of 2-chloro-1-iodine-4-methoxybenzene, such as solid state, specific melting point, boiling point, solubility and color state, are determined by its molecular structure, and are of great significance in organic synthesis, pharmaceutical chemistry and other fields. It is related to reaction conditions, separation and purification, and many other operations.
What is the market price of 2-chloro-1-iodo-4-methoxybenzene?
It is not easy to discuss the market price of 2-chloro-1-iodine-4-methoxybenzene today. The price often varies due to many factors, and the relevant information is difficult to obtain.
The first to bear the brunt is the price of raw materials. The preparation of this compound requires raw materials such as chlorine, iodine, and methoxy. If the price of raw materials fluctuates, the price of finished products will also change accordingly. For example, the source of chlorine, or due to differences in origin, season, supply and demand, the price is different; the same is true for iodine, its scarcity and market demand both affect its price, which in turn affects the cost and price of 2-chloro-1-iodine-4-methoxybenzene.
Preparation process is also the key. A delicate and efficient process can reduce costs and increase production, but its price may be slightly lower; if the process is cumbersome, time-consuming and laborious, and the yield is not high, the cost will rise and the price will be high. And different preparations have different processes and different prices.
Market supply and demand relationship is another important reason. If many industries, such as pharmaceuticals, chemicals, etc., have strong demand for this compound but limited supply, its price will rise; conversely, if demand is sluggish and supply exceeds demand, the price will fall. Such as pharmaceutical research and development, if the new drug needs this as a raw material, and the dosage is quite large, the market price will be affected by it.
In addition, regional differences also affect the price. In different places, the price varies due to different transportation costs, tax policies, and the degree of market competition. In distant places, the transportation journey is long, and the cost increases, the price may be higher than that in nearby places; in those with heavy taxes, merchants will also raise prices to ensure profits; and in places with intense competition, the price may be relatively low in order to compete for the market.
If you want to determine its market price, you need to constantly observe the chemical market conditions, consult professional chemical raw material suppliers, or check industry reports in order to obtain a more accurate price, and this price also changes with the above factors.
The first to bear the brunt is the price of raw materials. The preparation of this compound requires raw materials such as chlorine, iodine, and methoxy. If the price of raw materials fluctuates, the price of finished products will also change accordingly. For example, the source of chlorine, or due to differences in origin, season, supply and demand, the price is different; the same is true for iodine, its scarcity and market demand both affect its price, which in turn affects the cost and price of 2-chloro-1-iodine-4-methoxybenzene.
Preparation process is also the key. A delicate and efficient process can reduce costs and increase production, but its price may be slightly lower; if the process is cumbersome, time-consuming and laborious, and the yield is not high, the cost will rise and the price will be high. And different preparations have different processes and different prices.
Market supply and demand relationship is another important reason. If many industries, such as pharmaceuticals, chemicals, etc., have strong demand for this compound but limited supply, its price will rise; conversely, if demand is sluggish and supply exceeds demand, the price will fall. Such as pharmaceutical research and development, if the new drug needs this as a raw material, and the dosage is quite large, the market price will be affected by it.
In addition, regional differences also affect the price. In different places, the price varies due to different transportation costs, tax policies, and the degree of market competition. In distant places, the transportation journey is long, and the cost increases, the price may be higher than that in nearby places; in those with heavy taxes, merchants will also raise prices to ensure profits; and in places with intense competition, the price may be relatively low in order to compete for the market.
If you want to determine its market price, you need to constantly observe the chemical market conditions, consult professional chemical raw material suppliers, or check industry reports in order to obtain a more accurate price, and this price also changes with the above factors.
Scan to WhatsApp
