Linshang Chemical
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2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
932767 |
| Chemical Formula | C7H3ClF3NO2 |
| Molar Mass | 225.55 g/mol |
| Appearance | Typically a colorless to light - yellow liquid |
| Boiling Point | Around 205 - 207 °C |
| Density | 1.588 g/cm³ |
| Solubility | Insoluble in water, soluble in organic solvents like ethanol, ether |
| Flash Point | Around 83 °C |
| Vapor Pressure | Low vapor pressure at room temperature |
| Refractive Index | 1.486 |
As an accredited 2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 2 - chloro - 1 - nitro - 3 - (trifluoromethyl)benzene packaged in a sealed glass bottle. |
| Storage | 2 - chloro - 1 - nitro - 3 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames due to its potential flammability. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reducing agents to avoid dangerous reactions. Label the storage clearly for easy identification and safety. |
| Shipping | 2 - chloro - 1 - nitro - 3 - (trifluoromethyl)benzene is a hazardous chemical. Shipping requires proper packaging in accordance with regulations, with labels indicating its nature, and transport by carriers approved for such chemicals. |
Competitive 2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 2-Chloro-1-Nitro-3-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 2-chloro-1-nitro-3- (trifluoromethyl) benzene?
2-Chloro-1-nitro-3- (trifluoromethyl) benzene, this is an organic compound with a wide range of uses.
In the field of medicine, it is often used as a key intermediate. Through specific chemical reactions, its structure can be modified, and then compounds with specific pharmacological activities can be synthesized. For example, when developing antibacterial and anti-inflammatory drugs, this is used as the starting material, and new drugs with good efficacy can be prepared through multi-step reactions. Compounds containing trifluoromethyl often have unique physical, chemical and biological activities, which can enhance the interaction between drugs and targets, improve drug efficacy and selectivity.
In the field of pesticides, it also plays an important role. It can be used as a raw material for the synthesis of high-efficiency pesticides. The existence of trifluoromethyl can improve the fat solubility and stability of pesticides, making it easier to penetrate the surface of pests or plant cuticle, enhance the efficacy, and prolong the effective period. The synthesis of some new pesticides and herbicides is based on 2-chloro-1-nitro-3- (trifluoromethyl) benzene, which provides strong protection for agricultural production.
In terms of materials science, it can participate in the synthesis of special polymer materials. Due to its special structure, it endows the material with unique properties, such as high temperature resistance and chemical corrosion resistance. The synthesized polymer may be used in high-end fields such as aerospace and electronics to meet the strict requirements of material properties in special environments.
In addition, in the study of organic synthetic chemistry, it is often used as a model compound. Chemists use this to explore various chemical reaction mechanisms and develop new synthesis methods. Due to its complex structure and multiple functional groups, it can simulate many situations encountered in actual synthesis, providing a theoretical and practical basis for the development of organic synthetic chemistry.
In summary, 2-chloro-1-nitro-3- (trifluoromethyl) benzene has important uses in many fields such as medicine, pesticides, materials science and organic synthesis research, and is of great significance to promote the development of related fields.
In the field of medicine, it is often used as a key intermediate. Through specific chemical reactions, its structure can be modified, and then compounds with specific pharmacological activities can be synthesized. For example, when developing antibacterial and anti-inflammatory drugs, this is used as the starting material, and new drugs with good efficacy can be prepared through multi-step reactions. Compounds containing trifluoromethyl often have unique physical, chemical and biological activities, which can enhance the interaction between drugs and targets, improve drug efficacy and selectivity.
In the field of pesticides, it also plays an important role. It can be used as a raw material for the synthesis of high-efficiency pesticides. The existence of trifluoromethyl can improve the fat solubility and stability of pesticides, making it easier to penetrate the surface of pests or plant cuticle, enhance the efficacy, and prolong the effective period. The synthesis of some new pesticides and herbicides is based on 2-chloro-1-nitro-3- (trifluoromethyl) benzene, which provides strong protection for agricultural production.
In terms of materials science, it can participate in the synthesis of special polymer materials. Due to its special structure, it endows the material with unique properties, such as high temperature resistance and chemical corrosion resistance. The synthesized polymer may be used in high-end fields such as aerospace and electronics to meet the strict requirements of material properties in special environments.
In addition, in the study of organic synthetic chemistry, it is often used as a model compound. Chemists use this to explore various chemical reaction mechanisms and develop new synthesis methods. Due to its complex structure and multiple functional groups, it can simulate many situations encountered in actual synthesis, providing a theoretical and practical basis for the development of organic synthetic chemistry.
In summary, 2-chloro-1-nitro-3- (trifluoromethyl) benzene has important uses in many fields such as medicine, pesticides, materials science and organic synthesis research, and is of great significance to promote the development of related fields.
What are the physical properties of 2-chloro-1-nitro-3- (trifluoromethyl) benzene
2-Chloro-1-nitro-3- (trifluoromethyl) benzene is also an organic compound. Its physical properties are worth exploring, as follows:
Looking at its appearance, it often takes a colorless to light yellow liquid shape, which is the first characteristic that can be seen. It has a certain degree of volatility and can evaporate slowly in the air, causing a special smell to be smelled around it. This smell is pungent and irritating, and it is uncomfortable for people to smell.
When it comes to the boiling point, it is about 190-200 ° C. The boiling point is the critical temperature at which a substance changes from liquid to gaseous state. This boiling point indicates that the compound needs to reach this temperature under normal pressure before it can boil and vaporize. In terms of melting point, it is roughly around -20 ° C. The melting point is the temperature limit for a substance to change from solid to liquid. From this, it can be seen that it is a solid state at relatively low temperatures, and melts into a liquid state when the temperature rises slightly.
The compound has a higher density than water. If mixed with water, it will sink to the bottom of the water. And it is difficult to dissolve in water. Due to the large difference between its molecular structure and the polarity of water molecules, it is difficult to interact with water to form a uniform solution. However, it is soluble in many organic solvents, such as ethanol, ether, dichloromethane, etc. This is because there is a similar force between the organic solvent molecules, and it can dissolve each other according to the principle of "similar miscibility".
In addition, the vapor pressure of 2-chloro-1-nitro-3- (trifluoromethyl) benzene is also characteristic. At a certain temperature, its vapor pressure is relatively low, which means that its gasification rate is relatively slow at room temperature.
In summary, the physical properties of 2-chloro-1-nitro-3- (trifluoromethyl) benzene, such as appearance, odor, melting point, boiling point, density, solubility, and vapor pressure, together constitute its unique physical properties, which are of great significance in the research and application of organic chemistry.
Looking at its appearance, it often takes a colorless to light yellow liquid shape, which is the first characteristic that can be seen. It has a certain degree of volatility and can evaporate slowly in the air, causing a special smell to be smelled around it. This smell is pungent and irritating, and it is uncomfortable for people to smell.
When it comes to the boiling point, it is about 190-200 ° C. The boiling point is the critical temperature at which a substance changes from liquid to gaseous state. This boiling point indicates that the compound needs to reach this temperature under normal pressure before it can boil and vaporize. In terms of melting point, it is roughly around -20 ° C. The melting point is the temperature limit for a substance to change from solid to liquid. From this, it can be seen that it is a solid state at relatively low temperatures, and melts into a liquid state when the temperature rises slightly.
The compound has a higher density than water. If mixed with water, it will sink to the bottom of the water. And it is difficult to dissolve in water. Due to the large difference between its molecular structure and the polarity of water molecules, it is difficult to interact with water to form a uniform solution. However, it is soluble in many organic solvents, such as ethanol, ether, dichloromethane, etc. This is because there is a similar force between the organic solvent molecules, and it can dissolve each other according to the principle of "similar miscibility".
In addition, the vapor pressure of 2-chloro-1-nitro-3- (trifluoromethyl) benzene is also characteristic. At a certain temperature, its vapor pressure is relatively low, which means that its gasification rate is relatively slow at room temperature.
In summary, the physical properties of 2-chloro-1-nitro-3- (trifluoromethyl) benzene, such as appearance, odor, melting point, boiling point, density, solubility, and vapor pressure, together constitute its unique physical properties, which are of great significance in the research and application of organic chemistry.
What are the synthesis methods of 2-chloro-1-nitro-3- (trifluoromethyl) benzene
The synthesis methods of 2-chloro-1-nitro-3- (trifluoromethyl) benzene are quite diverse. The following are the common methods.
First, aromatic hydrocarbons are used as starting materials. First, aromatic hydrocarbons containing trifluoromethyl are taken, and nitrogenation is carried out to introduce nitro groups. This process requires careful selection of nitrifying reagents, such as mixed acids of concentrated nitric acid and concentrated sulfuric acid, and precise temperature control and reaction time to prevent side reactions of polynitrogenation. Subsequently, a halogenation reaction is carried out, and chlorine atoms are introduced at specific positions. When halogenating, a suitable halogenating agent, such as chlorine gas, can be used to react under the action of light or catalyst, so that the target product can be obtained.
Second, the halogenated aromatic hydrocarbon is used as the starting material. First, the aromatic hydrocarbon containing chlorine atoms is selected, and trifluoromethyl is introduced by a specific method. Nucleophilic substitution reaction can be used to react with suitable trifluoromethylating reagents. After that, the obtained product is nitrified, and nitro is introduced at the appropriate position to achieve the synthesis of the target product. The key to this path lies in the precise control of the reaction conditions at each step to ensure the selectivity and yield of the reaction.
Third, nitro aromatic hydrocarbons are used as the starting material. First, the aromatic hydrocarbons containing nitro groups are taken, chlorine atoms are introduced through halogenation reaction, and then trifluoromethyl is introduced by a specific method. The process of introducing trifluoromethyl may require the help of transition metal-catalyzed reactions, such as palladium catalysis, to achieve efficient trifluoromethylation, and finally obtain 2-chloro-1-nitro-3- (trifluoromethyl) benzene.
Each synthesis method has its advantages and disadvantages. In actual operation, the most suitable synthesis path is selected according to the availability of raw materials, the difficulty of reaction conditions, cost considerations, and the purity requirements of the target product.
First, aromatic hydrocarbons are used as starting materials. First, aromatic hydrocarbons containing trifluoromethyl are taken, and nitrogenation is carried out to introduce nitro groups. This process requires careful selection of nitrifying reagents, such as mixed acids of concentrated nitric acid and concentrated sulfuric acid, and precise temperature control and reaction time to prevent side reactions of polynitrogenation. Subsequently, a halogenation reaction is carried out, and chlorine atoms are introduced at specific positions. When halogenating, a suitable halogenating agent, such as chlorine gas, can be used to react under the action of light or catalyst, so that the target product can be obtained.
Second, the halogenated aromatic hydrocarbon is used as the starting material. First, the aromatic hydrocarbon containing chlorine atoms is selected, and trifluoromethyl is introduced by a specific method. Nucleophilic substitution reaction can be used to react with suitable trifluoromethylating reagents. After that, the obtained product is nitrified, and nitro is introduced at the appropriate position to achieve the synthesis of the target product. The key to this path lies in the precise control of the reaction conditions at each step to ensure the selectivity and yield of the reaction.
Third, nitro aromatic hydrocarbons are used as the starting material. First, the aromatic hydrocarbons containing nitro groups are taken, chlorine atoms are introduced through halogenation reaction, and then trifluoromethyl is introduced by a specific method. The process of introducing trifluoromethyl may require the help of transition metal-catalyzed reactions, such as palladium catalysis, to achieve efficient trifluoromethylation, and finally obtain 2-chloro-1-nitro-3- (trifluoromethyl) benzene.
Each synthesis method has its advantages and disadvantages. In actual operation, the most suitable synthesis path is selected according to the availability of raw materials, the difficulty of reaction conditions, cost considerations, and the purity requirements of the target product.
What to pay attention to when storing and transporting 2-chloro-1-nitro-3- (trifluoromethyl) benzene
2-Chloro-1-nitro-3- (trifluoromethyl) benzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
Bear the brunt, the storage environment is very important. It should be placed in a cool and ventilated place, away from fire and heat sources. The cover is dangerous due to the heat or open flame of the compound, such as the risk of combustion and explosion. This is to prevent its chemical properties from being excited by temperature and fire source, causing accidents.
Furthermore, it should be stored separately from oxidants, food chemicals, etc., and must not be mixed. Due to its chemical properties, it encounters with oxidants, or has a violent chemical reaction, causing danger; coexists with edible chemicals, if there is leakage, it is easy to cause disasters such as accidental ingestion.
Packaging should not be ignored. It is necessary to ensure that the packaging is complete and sealed. Packaging is in good condition to prevent leakage, prevent it from volatilizing in the air, polluting the environment, and prevent it from accidental contact with external substances and causing reactions.
When transporting, it is also necessary to be cautious. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In case of emergencies on the way, such as fire or leakage, they can be responded to in time to reduce losses.
During transportation, ensure that the container does not leak, collapse, fall, or damage. The driving should be stable to avoid bumps, collisions, and material leakage caused by damaged packaging.
And when transporting, it is strictly forbidden to mix with oxidants, edible chemicals, etc. This is to ensure transportation safety and avoid the interaction of different chemicals caused by mixed transportation, which breeds danger.
To sum up, the storage and transportation of 2-chloro-1-nitro-3- (trifluoromethyl) benzene requires strict attention to the environment, packaging, mixed storage, and transportation operations to ensure safety.
Bear the brunt, the storage environment is very important. It should be placed in a cool and ventilated place, away from fire and heat sources. The cover is dangerous due to the heat or open flame of the compound, such as the risk of combustion and explosion. This is to prevent its chemical properties from being excited by temperature and fire source, causing accidents.
Furthermore, it should be stored separately from oxidants, food chemicals, etc., and must not be mixed. Due to its chemical properties, it encounters with oxidants, or has a violent chemical reaction, causing danger; coexists with edible chemicals, if there is leakage, it is easy to cause disasters such as accidental ingestion.
Packaging should not be ignored. It is necessary to ensure that the packaging is complete and sealed. Packaging is in good condition to prevent leakage, prevent it from volatilizing in the air, polluting the environment, and prevent it from accidental contact with external substances and causing reactions.
When transporting, it is also necessary to be cautious. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In case of emergencies on the way, such as fire or leakage, they can be responded to in time to reduce losses.
During transportation, ensure that the container does not leak, collapse, fall, or damage. The driving should be stable to avoid bumps, collisions, and material leakage caused by damaged packaging.
And when transporting, it is strictly forbidden to mix with oxidants, edible chemicals, etc. This is to ensure transportation safety and avoid the interaction of different chemicals caused by mixed transportation, which breeds danger.
To sum up, the storage and transportation of 2-chloro-1-nitro-3- (trifluoromethyl) benzene requires strict attention to the environment, packaging, mixed storage, and transportation operations to ensure safety.
What are the environmental effects of 2-chloro-1-nitro-3- (trifluoromethyl) benzene?
2-Chloro-1-nitro-3- (trifluoromethyl) benzene, the impact of this substance on the environment needs to be reviewed in detail.
Its chemical properties are active, in the environment, or can participate in a variety of chemical reactions. First of all, its persistence, because of its special structure, containing chlorine, nitro and trifluoromethyl, makes its chemical stability quite high, and it is difficult to degrade in the natural environment. In the soil, it can remain for a long time, which in turn affects the soil quality, hinders the absorption of nutrients and water by plant roots, and causes plant growth to be trapped and stunted.
Again on its bioaccumulation, this compound is lipid-soluble, easy to biouptake and accumulate in organisms. Passed through the food chain, from lower organisms to higher organisms, the concentration increases step by step. If small fish accidentally eat plankton containing this substance, and big fish eat small fish, eventually if humans eat contaminated fish, this substance will enter the human body and endanger human health, such as damage to liver, kidneys and other organs.
Its toxicity to aquatic organisms should not be underestimated. Once it enters the water body, it will seriously interfere with the living environment of aquatic organisms. It can cause fish breathing difficulties, abnormal behavior, and even death; it may affect aquatic plants, or affect their photosynthesis and normal physiological metabolism, and destroy the balance of aquatic ecosystems.
In addition, this substance volatilizes into the atmosphere, or participates in photochemical reactions, which affects the air quality and has a negative impact on the surrounding ecological environment and human life.
Therefore, 2-chloro-1-nitro-3- (trifluoromethyl) benzene has a wide and severe impact on the environment, and should be strictly controlled in production, use and discharge to prevent it from causing greater harm to the environment.
Its chemical properties are active, in the environment, or can participate in a variety of chemical reactions. First of all, its persistence, because of its special structure, containing chlorine, nitro and trifluoromethyl, makes its chemical stability quite high, and it is difficult to degrade in the natural environment. In the soil, it can remain for a long time, which in turn affects the soil quality, hinders the absorption of nutrients and water by plant roots, and causes plant growth to be trapped and stunted.
Again on its bioaccumulation, this compound is lipid-soluble, easy to biouptake and accumulate in organisms. Passed through the food chain, from lower organisms to higher organisms, the concentration increases step by step. If small fish accidentally eat plankton containing this substance, and big fish eat small fish, eventually if humans eat contaminated fish, this substance will enter the human body and endanger human health, such as damage to liver, kidneys and other organs.
Its toxicity to aquatic organisms should not be underestimated. Once it enters the water body, it will seriously interfere with the living environment of aquatic organisms. It can cause fish breathing difficulties, abnormal behavior, and even death; it may affect aquatic plants, or affect their photosynthesis and normal physiological metabolism, and destroy the balance of aquatic ecosystems.
In addition, this substance volatilizes into the atmosphere, or participates in photochemical reactions, which affects the air quality and has a negative impact on the surrounding ecological environment and human life.
Therefore, 2-chloro-1-nitro-3- (trifluoromethyl) benzene has a wide and severe impact on the environment, and should be strictly controlled in production, use and discharge to prevent it from causing greater harm to the environment.
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