Linshang Chemical
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2-Chloro-1-Nitro-4-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
343102 |
| Chemical Formula | C7H3ClF3NO2 |
| Molar Mass | 225.55 g/mol |
| Appearance | liquid (usually) |
| Color | colorless to pale yellow |
| Odor | pungent odor |
| Boiling Point | 198 - 200 °C |
| Melting Point | - 18 °C |
| Density | 1.557 g/cm³ |
| Solubility In Water | insoluble |
| Solubility In Organic Solvents | soluble in many organic solvents |
| Flash Point | 83 °C |
| Vapor Pressure | low vapor pressure |
As an accredited 2-Chloro-1-Nitro-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 - gram bottle of 2 - chloro - 1 - nitro - 4 - (trifluoromethyl)benzene, well - sealed. |
| Storage | 2 - chloro - 1 - nitro - 4 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant material. Avoid storage near incompatible substances to prevent potential reactions. |
| Shipping | 2 - chloro - 1 - nitro - 4 - (trifluoromethyl)benzene is shipped in specialized, well - sealed containers compliant with hazardous chemical regulations. Transport is via approved carriers, ensuring proper handling to prevent spills and maintain safety during transit. |
Competitive 2-Chloro-1-Nitro-4-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-1-Nitro-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 2-chloro-1-nitro-4- (trifluoromethyl) benzene?
2-Chloro-1-nitro-4- (trifluoromethyl) benzene, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of chemical synthesis.
In the process of pharmaceutical synthesis, using this as the starting material, through multiple steps of delicate reactions, complex molecular structures with specific pharmacological activities can be constructed, thereby facilitating the creation of new drugs. The unique electronic effects and steric barriers of chlorine atoms, nitro groups and trifluoromethyl groups in the molecule endow the synthesized drugs with different biological activities and pharmacokinetic properties.
It also plays an important role in the field of materials science. It can be introduced into the structure of polymer materials through specific chemical reactions to improve the properties of materials. For example, it can enhance the chemical resistance of materials. Due to the strong electronegativity and stability of trifluoromethyl, it can resist the erosion of many chemical substances; it can also improve the heat resistance of materials, so that materials can still maintain good performance in high temperature environments.
Furthermore, in the synthesis of pesticides, 2-chloro-1-nitro-4- (trifluoromethyl) benzene is also indispensable. After rational design and reaction, efficient and low-toxic pesticide products can be prepared. The characteristics of molecular structure make it have good biological activity against specific pests or weeds, providing strong support for pest control in agricultural production.
Overall, 2-chloro-1-nitro-4- (trifluoromethyl) benzene has important applications in many fields such as medicine, materials, and pesticides due to its unique chemical structure, which is of great significance for promoting the development of related industries.
In the process of pharmaceutical synthesis, using this as the starting material, through multiple steps of delicate reactions, complex molecular structures with specific pharmacological activities can be constructed, thereby facilitating the creation of new drugs. The unique electronic effects and steric barriers of chlorine atoms, nitro groups and trifluoromethyl groups in the molecule endow the synthesized drugs with different biological activities and pharmacokinetic properties.
It also plays an important role in the field of materials science. It can be introduced into the structure of polymer materials through specific chemical reactions to improve the properties of materials. For example, it can enhance the chemical resistance of materials. Due to the strong electronegativity and stability of trifluoromethyl, it can resist the erosion of many chemical substances; it can also improve the heat resistance of materials, so that materials can still maintain good performance in high temperature environments.
Furthermore, in the synthesis of pesticides, 2-chloro-1-nitro-4- (trifluoromethyl) benzene is also indispensable. After rational design and reaction, efficient and low-toxic pesticide products can be prepared. The characteristics of molecular structure make it have good biological activity against specific pests or weeds, providing strong support for pest control in agricultural production.
Overall, 2-chloro-1-nitro-4- (trifluoromethyl) benzene has important applications in many fields such as medicine, materials, and pesticides due to its unique chemical structure, which is of great significance for promoting the development of related industries.
What are the physical properties of 2-chloro-1-nitro-4- (trifluoromethyl) benzene
2-Chloro-1-nitro-4- (trifluoromethyl) benzene, also an organic compound. Its physical properties are as follows:
In terms of color state, it is often a colorless to pale yellow liquid. Looking at it, it is clear and transparent, and if the morning light is poured on the lake, it shines brightly. At room temperature and pressure, this state is stable, just like a gentleman who is not alarmed and keeps his usual way.
In smell, it has a special aromatic smell, but you need to be cautious when smelling, because it may stimulate the sense of smell, like a rose with thorns, fragrant but hidden sharp.
Melting point and boiling point are also important physical properties. The melting point is about [X] ° C. When the temperature drops to this temperature, it is like a sleeping beast, gradually solidifying from a flowing state. The boiling point reaches about [X] ° C. When it rises to Swain, the molecules are abnormally active, break free from the shackles of the liquid phase, and turn into gaseous escapes.
Solubility, in organic solvents, such as ethanol, ether, etc., it is quite soluble, just like a fish entering water, and they blend seamlessly. However, in water, the solubility is very small, just like oil and water are difficult to mix, and the two are distinct.
Density is heavier than water. If it is placed in one place with water, such as a stone sinking to the bottom of the water, it will slowly settle and live in the lower layer.
In terms of volatility, it has a certain degree of volatility. In the air, its molecules are like smart birds, gradually escaping, but the evaporation rate is neither extremely fast nor extremely slow, and it is in a moderate state.
The refractive index also has a specific value. When light passes through, if it encounters a tortuous path, the direction is deflected. This is its unique optical property and an important basis for identification.
All these physical properties are of great significance in the fields of chemical industry and scientific research. They provide key reference for their application, separation, purification and other operations, like a beacon for navigation, guiding the direction.
In terms of color state, it is often a colorless to pale yellow liquid. Looking at it, it is clear and transparent, and if the morning light is poured on the lake, it shines brightly. At room temperature and pressure, this state is stable, just like a gentleman who is not alarmed and keeps his usual way.
In smell, it has a special aromatic smell, but you need to be cautious when smelling, because it may stimulate the sense of smell, like a rose with thorns, fragrant but hidden sharp.
Melting point and boiling point are also important physical properties. The melting point is about [X] ° C. When the temperature drops to this temperature, it is like a sleeping beast, gradually solidifying from a flowing state. The boiling point reaches about [X] ° C. When it rises to Swain, the molecules are abnormally active, break free from the shackles of the liquid phase, and turn into gaseous escapes.
Solubility, in organic solvents, such as ethanol, ether, etc., it is quite soluble, just like a fish entering water, and they blend seamlessly. However, in water, the solubility is very small, just like oil and water are difficult to mix, and the two are distinct.
Density is heavier than water. If it is placed in one place with water, such as a stone sinking to the bottom of the water, it will slowly settle and live in the lower layer.
In terms of volatility, it has a certain degree of volatility. In the air, its molecules are like smart birds, gradually escaping, but the evaporation rate is neither extremely fast nor extremely slow, and it is in a moderate state.
The refractive index also has a specific value. When light passes through, if it encounters a tortuous path, the direction is deflected. This is its unique optical property and an important basis for identification.
All these physical properties are of great significance in the fields of chemical industry and scientific research. They provide key reference for their application, separation, purification and other operations, like a beacon for navigation, guiding the direction.
What is the chemical synthesis method of 2-chloro-1-nitro-4- (trifluoromethyl) benzene?
The chemical synthesis of 2-chloro-1-nitro-4- (trifluoromethyl) benzene is an important issue in the field of organic synthesis. To prepare this compound, the following paths are often followed.
First, aromatic hydrocarbons containing trifluoromethyl are used as starting materials. For example, p-trifluoromethyl chlorobenzene can be taken first. This compound can be nitrified to introduce nitro groups. When nitrifying, the reaction conditions need to be carefully selected. Usually, a mixed acid of concentrated sulfuric acid and concentrated nitric acid is used as the nitrifying agent, and the reaction temperature is controlled at a suitable range, such as 0-10 ° C. Under this low temperature condition, the nitro group can be mainly substituted in the ortho-position of the chlorine atom to form 2-chloro-1-nitro-4- (trifluoromethyl) benzene. Because both the chlorine atom and the trifluoromethyl group are ortho-para-sites, under this condition, the ortho-substitution product is the main product.
Second, p-trifluoromethyl nitrobenzene can also be used as the starting material. Chlorine atoms are introduced through a halogenation reaction. Chlorine gas is often used as the halogenating agent and the reaction is carried out in the presence of a suitable catalyst. If iron powder or ferric chloride is used as the catalyst, under heating conditions, chlorine gas reacts with p-trifluoromethyl nitrobenzene, and chlorine atoms can replace hydrogen atoms on the benzene ring to form the target product 2-chloro-1-nitro-4- (trifluoromethyl) benzene.
During the synthesis process, many factors must be strictly controlled. The reaction temperature affects the selectivity of the product and the reaction rate; the proportion of the reactants is also crucial. If the ratio is not correct, it may cause an increase in side reactions and reduce the yield of the target product. In addition, the choice of reaction solvent also affects the reaction process. A solvent with good compatibility with the reactants and products and no adverse interference to the reaction should be selected. Post-processing steps are also indispensable. By means such as extraction, distillation, and recrystallization, the product can be purified and the purity of the product can be improved.
First, aromatic hydrocarbons containing trifluoromethyl are used as starting materials. For example, p-trifluoromethyl chlorobenzene can be taken first. This compound can be nitrified to introduce nitro groups. When nitrifying, the reaction conditions need to be carefully selected. Usually, a mixed acid of concentrated sulfuric acid and concentrated nitric acid is used as the nitrifying agent, and the reaction temperature is controlled at a suitable range, such as 0-10 ° C. Under this low temperature condition, the nitro group can be mainly substituted in the ortho-position of the chlorine atom to form 2-chloro-1-nitro-4- (trifluoromethyl) benzene. Because both the chlorine atom and the trifluoromethyl group are ortho-para-sites, under this condition, the ortho-substitution product is the main product.
Second, p-trifluoromethyl nitrobenzene can also be used as the starting material. Chlorine atoms are introduced through a halogenation reaction. Chlorine gas is often used as the halogenating agent and the reaction is carried out in the presence of a suitable catalyst. If iron powder or ferric chloride is used as the catalyst, under heating conditions, chlorine gas reacts with p-trifluoromethyl nitrobenzene, and chlorine atoms can replace hydrogen atoms on the benzene ring to form the target product 2-chloro-1-nitro-4- (trifluoromethyl) benzene.
During the synthesis process, many factors must be strictly controlled. The reaction temperature affects the selectivity of the product and the reaction rate; the proportion of the reactants is also crucial. If the ratio is not correct, it may cause an increase in side reactions and reduce the yield of the target product. In addition, the choice of reaction solvent also affects the reaction process. A solvent with good compatibility with the reactants and products and no adverse interference to the reaction should be selected. Post-processing steps are also indispensable. By means such as extraction, distillation, and recrystallization, the product can be purified and the purity of the product can be improved.
What are the precautions for storing and transporting 2-chloro-1-nitro-4- (trifluoromethyl) benzene?
2-Chloro-1-nitro-4- (trifluoromethyl) benzene is a highly toxic product. When storing and transporting, many matters must be taken with caution.
First words storage. First, it must be found in a cool, dry and well-ventilated place. This is because the material is prone to reaction when heated, and even the risk of explosion. If it is in a humid place, or it may cause hydrolysis and deterioration, it will affect quality and safety. Second, the storage place must be kept away from fire and heat sources. These chemicals are very easy to burn and explode in the event of open flames and hot topics, so it is essential to strictly prohibit fireworks. Third, it needs to be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed. Because of its contact with these substances, it is very likely to cause violent chemical reactions and cause accidents. Fourth, storage containers also need to be carefully selected. It is advisable to use corrosion-resistant materials, such as glass, specific plastic or metal materials, to ensure that the container is tightly sealed to prevent leakage.
Let's talk about transportation again. Transportation personnel must be professionally trained and well versed in the characteristics of the chemical and emergency treatment methods. Transportation vehicles must also meet safety standards and be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. On the way, you should drive at a steady speed and slowly to avoid violent actions such as sudden braking and sharp turns to prevent packaging damage. When transporting, you should also follow the specified route to avoid densely populated areas and important facilities. And the transportation process needs to be supervised by a special person, pay close attention to the condition of the goods, and take appropriate measures immediately once any abnormalities are detected.
In short, the storage and transportation of 2-chloro-1-nitro-4 - (trifluoromethyl) benzene are all about safety and cannot be sloppy at all. Every step and every detail must be strictly operated in accordance with regulations, so as to avoid risks to the greatest extent and ensure the safety of personnel and the environment.
First words storage. First, it must be found in a cool, dry and well-ventilated place. This is because the material is prone to reaction when heated, and even the risk of explosion. If it is in a humid place, or it may cause hydrolysis and deterioration, it will affect quality and safety. Second, the storage place must be kept away from fire and heat sources. These chemicals are very easy to burn and explode in the event of open flames and hot topics, so it is essential to strictly prohibit fireworks. Third, it needs to be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed. Because of its contact with these substances, it is very likely to cause violent chemical reactions and cause accidents. Fourth, storage containers also need to be carefully selected. It is advisable to use corrosion-resistant materials, such as glass, specific plastic or metal materials, to ensure that the container is tightly sealed to prevent leakage.
Let's talk about transportation again. Transportation personnel must be professionally trained and well versed in the characteristics of the chemical and emergency treatment methods. Transportation vehicles must also meet safety standards and be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. On the way, you should drive at a steady speed and slowly to avoid violent actions such as sudden braking and sharp turns to prevent packaging damage. When transporting, you should also follow the specified route to avoid densely populated areas and important facilities. And the transportation process needs to be supervised by a special person, pay close attention to the condition of the goods, and take appropriate measures immediately once any abnormalities are detected.
In short, the storage and transportation of 2-chloro-1-nitro-4 - (trifluoromethyl) benzene are all about safety and cannot be sloppy at all. Every step and every detail must be strictly operated in accordance with regulations, so as to avoid risks to the greatest extent and ensure the safety of personnel and the environment.
What are the effects of 2-chloro-1-nitro-4- (trifluoromethyl) benzene on the environment and human health?
2-Chloro-1-nitro-4- (trifluoromethyl) benzene is also an organic compound. It has an impact on the environment and human health.
In terms of the environment, this compound has certain stability and is not easy to degrade. If it flows into the soil, it may cause soil pollution, affect the soil microbial community, and damage the soil fertility and ecological balance. If it flows into the water body, it will also pollute the water source and cause toxicity to aquatic organisms. Because its structure contains chlorine, fluorine and nitro groups, or accumulates in the environment, it is transmitted and enriched through the food chain, endangering advanced organisms.
As for human health, this compound may enter the human body through inhalation, ingestion or skin contact. Chlorine, nitro and trifluoromethyl are all potentially toxic. Nitro can cause damage to the blood system, interfere with the oxygen-carrying function of hemoglobin, and make people prone to fatigue, dizziness, etc. Chlorine atoms may irritate the respiratory tract and skin, causing inflammation. The presence of trifluoromethyl may affect the human endocrine system, interfere with hormone balance, and cause adverse consequences to physiological processes such as reproduction and development. Long-term exposure may also increase the risk of cancer, because nitro compounds are metabolized in the body or form carcinogenic intermediates.
In summary, 2-chloro-1-nitro-4- (trifluoromethyl) benzene is potentially harmful to the environment and human health. When it is produced, used and handled, appropriate measures should be taken to reduce its adverse effects on the environment and human health.
In terms of the environment, this compound has certain stability and is not easy to degrade. If it flows into the soil, it may cause soil pollution, affect the soil microbial community, and damage the soil fertility and ecological balance. If it flows into the water body, it will also pollute the water source and cause toxicity to aquatic organisms. Because its structure contains chlorine, fluorine and nitro groups, or accumulates in the environment, it is transmitted and enriched through the food chain, endangering advanced organisms.
As for human health, this compound may enter the human body through inhalation, ingestion or skin contact. Chlorine, nitro and trifluoromethyl are all potentially toxic. Nitro can cause damage to the blood system, interfere with the oxygen-carrying function of hemoglobin, and make people prone to fatigue, dizziness, etc. Chlorine atoms may irritate the respiratory tract and skin, causing inflammation. The presence of trifluoromethyl may affect the human endocrine system, interfere with hormone balance, and cause adverse consequences to physiological processes such as reproduction and development. Long-term exposure may also increase the risk of cancer, because nitro compounds are metabolized in the body or form carcinogenic intermediates.
In summary, 2-chloro-1-nitro-4- (trifluoromethyl) benzene is potentially harmful to the environment and human health. When it is produced, used and handled, appropriate measures should be taken to reduce its adverse effects on the environment and human health.
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