Linshang Chemical
PRODUCTS
2-Chloro-3,4-Difluoronitrobenzene
Linshang Chemical
|
HS Code |
547323 |
| Chemical Formula | C6H2ClF2NO2 |
| Appearance | A yellow to brown liquid |
| Boiling Point | 226 - 228 °C |
| Melting Point | N/A |
| Density | 1.565 g/cm³ |
| Solubility In Water | Insoluble |
| Flash Point | 101 °C |
| Vapor Pressure | Low |
| Odor | Characteristic odor |
| Stability | Stable under normal conditions |
As an accredited 2-Chloro-3,4-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 - gram bottle of 2 - chloro - 3,4 - difluoronitrobenzene with secure chemical - grade packaging. |
| Storage | 2 - Chloro - 3,4 - difluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage. Due to its potential hazards, it should be separated from incompatible substances and stored in a designated area in accordance with safety regulations. |
| Shipping | 2 - Chloro - 3,4 - difluoronitrobenzene is shipped in accordance with strict chemical regulations. Packed in suitable corrosion - resistant containers, it's transported by approved carriers, ensuring safety during transit. |
Competitive 2-Chloro-3,4-Difluoronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-3,4-Difluoronitrobenzene in China?
As a trusted 2-Chloro-3,4-Difluoronitrobenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-3,4-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 2-chloro-3, 4-difluoronitrobenzene
2-Chloro-3,4-difluoronitrobenzene is a crucial intermediate in the field of organic synthesis. Its main uses are quite extensive, and it plays a key role in the preparation of many fine chemicals.
The first to bear the brunt is in the field of pharmaceutical synthesis. With this as the starting material, a series of delicate chemical reactions can be used to prepare a variety of therapeutic drugs. For example, in the synthesis of some antibacterial drugs, 2-chloro-3,4-difluoronitrobenzene is an indispensable basic substance. Its structural properties enable it to precisely combine with other compounds to gradually build complex drug molecular structures with specific pharmacological activities.
Furthermore, in the field of pesticides, 2-chloro-3,4-difluoronitrobenzene also plays an important role. It is often used as an important intermediate in the creation of many high-efficiency and low-toxicity pesticide varieties. With its unique chemical activity, a series of pesticide ingredients with good control effects on crop diseases and insect pests can be derived, escorting the harvest of agriculture.
In addition, in the dye industry, this compound also has extraordinary performance. After specific chemical transformation, it can synthesize dyes with bright color and good stability. Its molecular structure can endow dyes with unique color characteristics and dyeing properties during the dye synthesis process, meeting the needs of different textile materials and printing and dyeing processes.
In conclusion, 2-chloro-3,4-difluoronitrobenzene plays a pivotal role in many important industries related to the national economy and people's livelihood, such as medicine, pesticides, and dyes. It is a rare key intermediate in the field of organic synthetic chemistry.
The first to bear the brunt is in the field of pharmaceutical synthesis. With this as the starting material, a series of delicate chemical reactions can be used to prepare a variety of therapeutic drugs. For example, in the synthesis of some antibacterial drugs, 2-chloro-3,4-difluoronitrobenzene is an indispensable basic substance. Its structural properties enable it to precisely combine with other compounds to gradually build complex drug molecular structures with specific pharmacological activities.
Furthermore, in the field of pesticides, 2-chloro-3,4-difluoronitrobenzene also plays an important role. It is often used as an important intermediate in the creation of many high-efficiency and low-toxicity pesticide varieties. With its unique chemical activity, a series of pesticide ingredients with good control effects on crop diseases and insect pests can be derived, escorting the harvest of agriculture.
In addition, in the dye industry, this compound also has extraordinary performance. After specific chemical transformation, it can synthesize dyes with bright color and good stability. Its molecular structure can endow dyes with unique color characteristics and dyeing properties during the dye synthesis process, meeting the needs of different textile materials and printing and dyeing processes.
In conclusion, 2-chloro-3,4-difluoronitrobenzene plays a pivotal role in many important industries related to the national economy and people's livelihood, such as medicine, pesticides, and dyes. It is a rare key intermediate in the field of organic synthetic chemistry.
2-Chloro-3, what are the physical properties of 4-difluoronitrobenzene
2-Chloro-3,4-difluoronitrobenzene is one of the organic compounds. Its physical properties are very important and are related to its application in many fields.
First of all, its appearance, at room temperature, is mostly colorless to light yellow liquid, pure color and clear appearance. This appearance characteristic is quite critical when identifying and preliminarily judging its state.
Second, its boiling point is about a certain temperature range. The boiling point is the critical temperature at which a substance changes from liquid to gaseous state. The boiling point of 2-chloro-3,4-difluoronitrobenzene makes it possible to realize the phase transition under specific temperature conditions, which is very important in chemical operations such as distillation and separation. By precisely controlling the temperature, the compound can be effectively separated and its pure product can be obtained.
Furthermore, the melting point is also one of its important physical properties. The melting point is the temperature at which a substance melts from a solid state to a liquid state. The melting point of 2-chloro-3,4-difluoronitrobenzene determines its physical form under different temperature environments. At lower temperatures, or in a solid state, it is easy to store and transport; and when the temperature rises above the melting point, it melts into a liquid state and can participate in various chemical reactions.
In addition, the density cannot be ignored. Its density is a certain value, reflecting the mass of the substance per unit volume. This property plays a significant role in processes involving liquid mixing and delamination. With the difference in density, different substances can be separated by means of liquid separation.
Solubility is also a key property. 2-Chloro-3,4-difluoronitrobenzene has a certain solubility in organic solvents and can be soluble in solvents such as certain aromatics and halogenated hydrocarbons. However, the solubility in water is poor, so this difference makes it reasonable for use in reaction operations such as extraction and phase transfer catalysis.
The vapor pressure of this compound also has a specific value. Vapor pressure is related to its degree of volatilization. When the vapor pressure is higher, it is more likely to evaporate into the air under the same conditions. Understanding this property can effectively prevent safety hazards and environmental pollution caused by volatilization during safe production, storage and use.
The physical properties of 2-chloro-3,4-difluoronitrobenzene, such as appearance, boiling point, melting point, density, solubility and vapor pressure, are related to each other and jointly determine its application and operation in chemical, pharmaceutical and other fields. Knowing these properties, this compound can be used rationally to maximize its effectiveness and ensure safe and efficient operation.
First of all, its appearance, at room temperature, is mostly colorless to light yellow liquid, pure color and clear appearance. This appearance characteristic is quite critical when identifying and preliminarily judging its state.
Second, its boiling point is about a certain temperature range. The boiling point is the critical temperature at which a substance changes from liquid to gaseous state. The boiling point of 2-chloro-3,4-difluoronitrobenzene makes it possible to realize the phase transition under specific temperature conditions, which is very important in chemical operations such as distillation and separation. By precisely controlling the temperature, the compound can be effectively separated and its pure product can be obtained.
Furthermore, the melting point is also one of its important physical properties. The melting point is the temperature at which a substance melts from a solid state to a liquid state. The melting point of 2-chloro-3,4-difluoronitrobenzene determines its physical form under different temperature environments. At lower temperatures, or in a solid state, it is easy to store and transport; and when the temperature rises above the melting point, it melts into a liquid state and can participate in various chemical reactions.
In addition, the density cannot be ignored. Its density is a certain value, reflecting the mass of the substance per unit volume. This property plays a significant role in processes involving liquid mixing and delamination. With the difference in density, different substances can be separated by means of liquid separation.
Solubility is also a key property. 2-Chloro-3,4-difluoronitrobenzene has a certain solubility in organic solvents and can be soluble in solvents such as certain aromatics and halogenated hydrocarbons. However, the solubility in water is poor, so this difference makes it reasonable for use in reaction operations such as extraction and phase transfer catalysis.
The vapor pressure of this compound also has a specific value. Vapor pressure is related to its degree of volatilization. When the vapor pressure is higher, it is more likely to evaporate into the air under the same conditions. Understanding this property can effectively prevent safety hazards and environmental pollution caused by volatilization during safe production, storage and use.
The physical properties of 2-chloro-3,4-difluoronitrobenzene, such as appearance, boiling point, melting point, density, solubility and vapor pressure, are related to each other and jointly determine its application and operation in chemical, pharmaceutical and other fields. Knowing these properties, this compound can be used rationally to maximize its effectiveness and ensure safe and efficient operation.
What are the synthesis methods of 2-chloro-3, 4-difluoronitrobenzene
There are various ways to synthesize 2-chloro-3,4-difluoronitrobenzene. First, nitrobenzene can be started from nitrobenzene. Nitrobenzene is first halogenated, and chlorine atoms and fluorine atoms are introduced at specific positions in the benzene ring with a suitable halogenating agent. This process requires fine control of the reaction process, because the selectivity of the halogenation reaction is very critical, there is a slight difference in the pool, or the product can be mixed with other halogenated positions.
Second, halogenated benzene can also be used as a raw material. Nitro is introduced first, and nitrifying reagents are commonly used, such as a mixed acid system of concentrated nitric acid and concentrated sulfuric acid. After the introduction of nitro, a halogenation reaction is carried out to introduce the remaining halogen atoms. In this pathway, the localization effect of nitro and halogen atoms must be carefully considered in order to guide the required substitution mode of the target product.
Furthermore, the reaction of organometallic reagents can be used. Halogenated aromatics are used as substrates to interact with organometallic reagents, such as Grignard reagents or lithium reagents, and specific halogen atoms are introduced through exchange reactions with halogen atoms. This method can precisely control the substitution position, but the preparation and use conditions of organometallic reagents are relatively strict, and it needs to be operated in an anhydrous and anaerobic environment.
Or use nucleophilic substitution reaction. When there are suitable leaving groups on the benzene ring, the halogen-containing nucleophilic reagents are attacked to achieve the introduction of halogen atoms. This method has high requirements for the activity of leaving groups, and the regulation of reaction conditions, such as the choice of solvent and base, has a profound impact on the success or failure of the reaction and the purity of the product.
Synthesis of 2-chloro-3,4-difluoronitrobenzene has its own advantages and disadvantages. The appropriate synthesis path must be carefully selected according to the actual situation, such as raw material availability, cost considerations, product purity requirements, etc.
Second, halogenated benzene can also be used as a raw material. Nitro is introduced first, and nitrifying reagents are commonly used, such as a mixed acid system of concentrated nitric acid and concentrated sulfuric acid. After the introduction of nitro, a halogenation reaction is carried out to introduce the remaining halogen atoms. In this pathway, the localization effect of nitro and halogen atoms must be carefully considered in order to guide the required substitution mode of the target product.
Furthermore, the reaction of organometallic reagents can be used. Halogenated aromatics are used as substrates to interact with organometallic reagents, such as Grignard reagents or lithium reagents, and specific halogen atoms are introduced through exchange reactions with halogen atoms. This method can precisely control the substitution position, but the preparation and use conditions of organometallic reagents are relatively strict, and it needs to be operated in an anhydrous and anaerobic environment.
Or use nucleophilic substitution reaction. When there are suitable leaving groups on the benzene ring, the halogen-containing nucleophilic reagents are attacked to achieve the introduction of halogen atoms. This method has high requirements for the activity of leaving groups, and the regulation of reaction conditions, such as the choice of solvent and base, has a profound impact on the success or failure of the reaction and the purity of the product.
Synthesis of 2-chloro-3,4-difluoronitrobenzene has its own advantages and disadvantages. The appropriate synthesis path must be carefully selected according to the actual situation, such as raw material availability, cost considerations, product purity requirements, etc.
2-chloro-3, what are the precautions in storage and transportation of 4-difluoronitrobenzene
2-Chloro-3,4-difluoronitrobenzene is a chemical substance. When storing and transporting, pay attention to many matters.
When storing, the first environment. It should be placed in a cool and ventilated warehouse, because the substance is prone to change when heated. If it is in a high temperature, it may cause its chemical properties to be unstable and even cause danger. The temperature of the warehouse should be controlled within a suitable range and should not be too high.
Furthermore, it needs to be isolated from other substances. This substance has a certain chemical activity and should be kept away from fire and heat sources, and should not be co-stored with oxidants, reducing agents, alkalis, etc. Due to contact with it, or severe chemical reactions, such as combustion and explosion, endanger safety.
Storage containers should also be careful. A sealed container must be used to prevent it from evaporating and leaking. If it leaks outside, it will not only damage the environment, but also harm people's health if they touch it or smell it.
As for transportation, it should not be ignored. Transportation vehicles should be equipped with corresponding fire equipment to prevent accidents. And during transportation, make sure that the container does not leak, collapse, fall or damage.
The route of driving is also determined. It is not possible to pass through densely populated areas to avoid accidents and injuries. Transportation personnel must be familiar with the characteristics of this object and emergency treatment methods, and be careful on the way and not slack off. In this way, the safety of storage and transportation can be guaranteed.
When storing, the first environment. It should be placed in a cool and ventilated warehouse, because the substance is prone to change when heated. If it is in a high temperature, it may cause its chemical properties to be unstable and even cause danger. The temperature of the warehouse should be controlled within a suitable range and should not be too high.
Furthermore, it needs to be isolated from other substances. This substance has a certain chemical activity and should be kept away from fire and heat sources, and should not be co-stored with oxidants, reducing agents, alkalis, etc. Due to contact with it, or severe chemical reactions, such as combustion and explosion, endanger safety.
Storage containers should also be careful. A sealed container must be used to prevent it from evaporating and leaking. If it leaks outside, it will not only damage the environment, but also harm people's health if they touch it or smell it.
As for transportation, it should not be ignored. Transportation vehicles should be equipped with corresponding fire equipment to prevent accidents. And during transportation, make sure that the container does not leak, collapse, fall or damage.
The route of driving is also determined. It is not possible to pass through densely populated areas to avoid accidents and injuries. Transportation personnel must be familiar with the characteristics of this object and emergency treatment methods, and be careful on the way and not slack off. In this way, the safety of storage and transportation can be guaranteed.
What are the effects of 2-chloro-3, 4-difluoronitrobenzene on the environment and human health?
2-Chloro-3,4-difluoronitrobenzene is also an organic compound. It is often used as a synthetic raw material in the industrial field. However, this substance has potential effects on the environment and human health.
Discuss the impact on the environment. If it is released into the atmosphere, it will undergo photochemical reactions, affect air quality, and can be transported over long distances, causing regional air pollution. If it flows into water bodies, it will accumulate in aquatic ecosystems, poison aquatic organisms, and cause biodiversity loss. If it is contained in soil, it will affect soil microbial activity, destroy soil ecological balance, hinder plant growth, and penetrate into groundwater, polluting water sources.
As for the impact on human health, it is irritating. If skin contact, it can cause redness, swelling, pain, itching, and even burns. Eye contact can cause eye pain, tears, blurred vision, and vision loss in severe cases. If inhaled, irritate the respiratory tract, causing cough, asthma, breathing difficulties, long-term inhalation or increase the risk of respiratory diseases. After ingesting, it can damage the digestive system, causing nausea, vomiting, abdominal pain, diarrhea, and even damage to liver, kidney and other organs. In addition, due to its chemical structure, or potentially carcinogenic, long-term exposure to it may increase the risk of cancer. Therefore, in the production and use of 2-chloro-3,4-difluoronitrobenzene, it is necessary to adhere to safety procedures, take protective measures, and properly dispose of waste to reduce its harm to the environment and human health.
Discuss the impact on the environment. If it is released into the atmosphere, it will undergo photochemical reactions, affect air quality, and can be transported over long distances, causing regional air pollution. If it flows into water bodies, it will accumulate in aquatic ecosystems, poison aquatic organisms, and cause biodiversity loss. If it is contained in soil, it will affect soil microbial activity, destroy soil ecological balance, hinder plant growth, and penetrate into groundwater, polluting water sources.
As for the impact on human health, it is irritating. If skin contact, it can cause redness, swelling, pain, itching, and even burns. Eye contact can cause eye pain, tears, blurred vision, and vision loss in severe cases. If inhaled, irritate the respiratory tract, causing cough, asthma, breathing difficulties, long-term inhalation or increase the risk of respiratory diseases. After ingesting, it can damage the digestive system, causing nausea, vomiting, abdominal pain, diarrhea, and even damage to liver, kidney and other organs. In addition, due to its chemical structure, or potentially carcinogenic, long-term exposure to it may increase the risk of cancer. Therefore, in the production and use of 2-chloro-3,4-difluoronitrobenzene, it is necessary to adhere to safety procedures, take protective measures, and properly dispose of waste to reduce its harm to the environment and human health.
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