Linshang Chemical
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2-Chloro-4,6-Difluorobenzenesulfonyl Chloride
Linshang Chemical
|
HS Code |
670764 |
| Chemical Formula | C6HCl2F2O2S |
| Molecular Weight | 259.036 |
| Appearance | Typically a colorless to light - yellow liquid |
| Boiling Point | Data may vary, but generally in a certain range related to its molecular structure |
| Melting Point | Specific value depends on purity and other factors |
| Density | Appropriate value based on its chemical nature |
| Solubility | Soluble in some organic solvents like dichloromethane |
| Vapor Pressure | Related to its volatility at different temperatures |
| Flash Point | Value indicating fire - hazard potential |
| Reactivity | Reactive towards nucleophiles due to the presence of sulfonyl chloride group |
As an accredited 2-Chloro-4,6-Difluorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2 - chloro - 4,6 - difluorobenzenesulfonyl chloride in a sealed chemical - grade bottle. |
| Storage | 2 - chloro - 4,6 - difluorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances such as strong bases, oxidizing agents, and reducing agents. Store it in a tightly - sealed container to prevent leakage and exposure to air and moisture, which could cause decomposition or reaction. |
| Shipping | 2 - chloro - 4,6 - difluorobenzenesulfonyl chloride is a chemical. Ship it in tightly sealed, corrosion - resistant containers. Follow proper hazardous material shipping regulations, ensuring proper labeling and handling to prevent leaks and ensure safety during transit. |
Competitive 2-Chloro-4,6-Difluorobenzenesulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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Where to Buy 2-Chloro-4,6-Difluorobenzenesulfonyl Chloride in China?
As a trusted 2-Chloro-4,6-Difluorobenzenesulfonyl Chloride manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-4,6-Difluorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2-chloro-4, 6-difluorobenzenesulfonyl Chloride
2-Chloro-4,6-difluorobenzenesulfonyl chloride, this is an organic compound. Its chemical properties are unique and allow me to elaborate.
First of all, its reactivity, the chlorine atom and the sulfonyl chloride group in this compound are highly reactive. Sulfonyl chloride group (-SO 2O Cl) is extremely active and can often participate in many chemical reactions. In nucleophilic substitution reactions, the chlorine atom of the sulfonyl chloride group is easily attacked by nucleophiles and then replaced. For example, when reacted with alcohols, sulfonates can be formed; when reacted with amines, sulfonamides are formed.
Furthermore, the chlorine atom and fluorine atom on the benzene ring also affect its chemical properties. The fluorine atom has strong electronegativity, which will reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution reaction activity on the benzene ring. However, due to the presence of sulfonyl chloride in 2-chloro-4,6-difluorobenzenesulfonyl chloride, the reactivity is different. It can react with metal-organic reagents, such as Grignard reagent, and introduce new groups on the benzene ring.
In addition, 2-chloro-4,6-difluorobenzenesulfonyl chloride is more sensitive to water. When exposed to water, the sulfonyl chloride group is prone to hydrolysis, resulting in the corresponding sulfonic acid and hydrogen chloride. This hydrolysis reaction is easy to carry out in a humid environment, so it is necessary to pay attention to moisture-proof when storing and using.
In conclusion, 2-chloro-4,6-difluorobenzenesulfonyl chloride can be used as an important intermediate in the field of organic synthesis due to its special structure and active chemical properties. It is necessary to pay attention to its sensitivity to water and the control of reaction conditions.
First of all, its reactivity, the chlorine atom and the sulfonyl chloride group in this compound are highly reactive. Sulfonyl chloride group (-SO 2O Cl) is extremely active and can often participate in many chemical reactions. In nucleophilic substitution reactions, the chlorine atom of the sulfonyl chloride group is easily attacked by nucleophiles and then replaced. For example, when reacted with alcohols, sulfonates can be formed; when reacted with amines, sulfonamides are formed.
Furthermore, the chlorine atom and fluorine atom on the benzene ring also affect its chemical properties. The fluorine atom has strong electronegativity, which will reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution reaction activity on the benzene ring. However, due to the presence of sulfonyl chloride in 2-chloro-4,6-difluorobenzenesulfonyl chloride, the reactivity is different. It can react with metal-organic reagents, such as Grignard reagent, and introduce new groups on the benzene ring.
In addition, 2-chloro-4,6-difluorobenzenesulfonyl chloride is more sensitive to water. When exposed to water, the sulfonyl chloride group is prone to hydrolysis, resulting in the corresponding sulfonic acid and hydrogen chloride. This hydrolysis reaction is easy to carry out in a humid environment, so it is necessary to pay attention to moisture-proof when storing and using.
In conclusion, 2-chloro-4,6-difluorobenzenesulfonyl chloride can be used as an important intermediate in the field of organic synthesis due to its special structure and active chemical properties. It is necessary to pay attention to its sensitivity to water and the control of reaction conditions.
What are the common synthesis methods of 2-chloro-4, 6-difluorobenzenesulfonyl Chloride
2-Chloro-4,6-difluorobenzenesulfonyl chloride is an important intermediate in organic synthesis. The common synthesis methods are as follows:
First, 2-chloro-4,6-difluorobenzoic acid is used as the starting material. The acid is heated with sulfoxide chloride, and the carboxyl group in the acid can be converted into an acyl chloride group. Sulfoxide chloride is a commonly used chlorination reagent. In this reaction, it interacts with the carboxyl group to form the corresponding acid chloride, and escapes sulfur dioxide and hydrogen chloride gas. When reacting, it is necessary to pay attention to the control of temperature, preferably in a moderate temperature range, usually slightly higher than the boiling point of sulfoxide chloride, in order to promote the smooth progress of the reaction and avoid the growth of side reactions.
Second, use 2-chloro-4,6-difluorobenzene as the starting material. First make it blend with fuming sulfuric acid and chlorosulfonic acid to carry out a sulfonation reaction. Fuming sulfuric acid and chlorosulfonic acid have strong sulfonation ability, and sulfonyl groups can be introduced on the benzene ring. After the reaction is completed, the sulfonyl group is converted into sulfonyl chloride by chlorinated reagents such as phosphorus pentachloride or phosphorus trichloride. In this process, the conditions of the sulfonation reaction are very critical, and the temperature and the ratio of reagents will affect the yield and The chlorination step also requires fine operation to ensure the complete reaction and avoid side reactions such as excessive chlorination.
Third, if benzene derivatives containing appropriate substituents are used as starting materials, the structure of the target molecule is gradually constructed through a series of reactions such as halogenation, sulfonation, and chlorination. The halogenation reaction can choose suitable halogenating reagents, such as chlorine gas, bromine, etc. Under the action of catalysts, halogen atoms are introduced at specific positions in the benzene ring. The subsequent sulfonation and chlorination reactions are similar to the previous methods, but the reaction conditions need to be finely adjusted according to the structural characteristics of the starting materials to achieve the purpose of efficient synthesis of 2-chloro-4,6-difluorobenzenesulfonyl chloride.
First, 2-chloro-4,6-difluorobenzoic acid is used as the starting material. The acid is heated with sulfoxide chloride, and the carboxyl group in the acid can be converted into an acyl chloride group. Sulfoxide chloride is a commonly used chlorination reagent. In this reaction, it interacts with the carboxyl group to form the corresponding acid chloride, and escapes sulfur dioxide and hydrogen chloride gas. When reacting, it is necessary to pay attention to the control of temperature, preferably in a moderate temperature range, usually slightly higher than the boiling point of sulfoxide chloride, in order to promote the smooth progress of the reaction and avoid the growth of side reactions.
Second, use 2-chloro-4,6-difluorobenzene as the starting material. First make it blend with fuming sulfuric acid and chlorosulfonic acid to carry out a sulfonation reaction. Fuming sulfuric acid and chlorosulfonic acid have strong sulfonation ability, and sulfonyl groups can be introduced on the benzene ring. After the reaction is completed, the sulfonyl group is converted into sulfonyl chloride by chlorinated reagents such as phosphorus pentachloride or phosphorus trichloride. In this process, the conditions of the sulfonation reaction are very critical, and the temperature and the ratio of reagents will affect the yield and The chlorination step also requires fine operation to ensure the complete reaction and avoid side reactions such as excessive chlorination.
Third, if benzene derivatives containing appropriate substituents are used as starting materials, the structure of the target molecule is gradually constructed through a series of reactions such as halogenation, sulfonation, and chlorination. The halogenation reaction can choose suitable halogenating reagents, such as chlorine gas, bromine, etc. Under the action of catalysts, halogen atoms are introduced at specific positions in the benzene ring. The subsequent sulfonation and chlorination reactions are similar to the previous methods, but the reaction conditions need to be finely adjusted according to the structural characteristics of the starting materials to achieve the purpose of efficient synthesis of 2-chloro-4,6-difluorobenzenesulfonyl chloride.
Where is 2-chloro-4, 6-difluorobenzenesulfonyl Chloride used?
2-Chloro-4,6-difluorobenzenesulfonyl chloride is useful in various fields. In the field of Guanfu Chemical Industry, it is often a key material for organic synthesis. It can be used to create various fluorine-containing fine chemicals. Due to the unique properties of fluorine atoms, such as high electronegativity and small atomic radius, it can make the generated products have specific properties and demonstrate advantages in medicine, pesticides, materials and many other aspects.
In the pharmaceutical industry, drug molecules with high activity can be synthesized through this material. Because of its unique structure, it may accurately fit biological targets, enhance the affinity between drugs and receptors, improve drug efficacy, and reduce toxic and side effects. For example, a specific chemical structure can be constructed through a series of reactions to fight certain difficult diseases, such as specific tumor diseases, and to help human health.
As for the field of pesticides, 2-chloro-4,6-difluorobenzenesulfonyl chloride is also important. It can help synthesize pesticides with excellent insecticidal, bactericidal and herbicidal effects. Its fluorine-containing structure can enhance the stability and biological activity of pesticides, enabling them to maintain their efficacy in complex and changing natural environments for a long time, accurately attack pests, and escort agricultural harvests.
Furthermore, in the field of materials science, fluorinated materials made from this raw material have shown extraordinary performance. Such as fluoropolymer materials, or with excellent weather resistance, chemical corrosion resistance, can be used as high-end coatings, special plastics, etc., used in aerospace, automobile manufacturing and other high-end industries to improve the quality and performance of materials.
In summary, although 2-chloro-4,6-difluorobenzenesulfonyl chloride is a chemical substance, it plays a crucial role in many fields such as chemical industry, medicine, pesticides, materials, etc., and plays a crucial role in promoting scientific and technological progress and industrial development in various fields.
In the pharmaceutical industry, drug molecules with high activity can be synthesized through this material. Because of its unique structure, it may accurately fit biological targets, enhance the affinity between drugs and receptors, improve drug efficacy, and reduce toxic and side effects. For example, a specific chemical structure can be constructed through a series of reactions to fight certain difficult diseases, such as specific tumor diseases, and to help human health.
As for the field of pesticides, 2-chloro-4,6-difluorobenzenesulfonyl chloride is also important. It can help synthesize pesticides with excellent insecticidal, bactericidal and herbicidal effects. Its fluorine-containing structure can enhance the stability and biological activity of pesticides, enabling them to maintain their efficacy in complex and changing natural environments for a long time, accurately attack pests, and escort agricultural harvests.
Furthermore, in the field of materials science, fluorinated materials made from this raw material have shown extraordinary performance. Such as fluoropolymer materials, or with excellent weather resistance, chemical corrosion resistance, can be used as high-end coatings, special plastics, etc., used in aerospace, automobile manufacturing and other high-end industries to improve the quality and performance of materials.
In summary, although 2-chloro-4,6-difluorobenzenesulfonyl chloride is a chemical substance, it plays a crucial role in many fields such as chemical industry, medicine, pesticides, materials, etc., and plays a crucial role in promoting scientific and technological progress and industrial development in various fields.
What are the storage conditions for 2-chloro-4, 6-difluorobenzenesulfonyl Chloride?
2-Chloro-4,6-difluorobenzenesulfonyl chloride is also a chemical substance. Its storage conditions are crucial, which is related to the stability and safety of the substance.
This substance should be stored in a cool, dry and well-ventilated place. In a cool place, the temperature should not be too high, because high temperature can easily cause chemical reactions, or decomposition, or cause other unstable changes. The temperature should be maintained at 15 to 25 degrees Celsius, so that its chemical properties can be relatively stable.
A dry environment is also indispensable. If the moisture in the air comes into contact with 2-chloro-4,6-difluorobenzenesulfonyl chloride, it may promote its hydrolysis reaction, cause it to deteriorate, and lose its original chemical properties and functions. Therefore, the storage place must be moisture-proof, and a desiccant can be placed nearby to absorb water vapor in the air.
Well ventilated can disperse harmful gases that may be generated by the volatilization of substances in time to avoid danger caused by gas accumulation. And ventilation can maintain the fresh air in the storage environment and reduce the risk of accidents caused by high gas concentration.
Furthermore, when storing, it should be stored separately from oxidants, alkalis and other substances. Oxidants have strong oxidizing properties, or react violently with 2-chloro-4,6-difluorobenzenesulfonyl chloride; alkali substances may also react chemically with them, which will endanger storage safety. The two must be isolated and kept at a certain distance.
In addition, storage containers should also be carefully selected. Corrosion-resistant materials should be selected, such as specific glass materials or plastic containers that meet requirements, to prevent the container from being corroded, causing material leakage and causing safety accidents. And the container must be well sealed to ensure that outside air, moisture, etc. are difficult to invade.
Storage places should also be set up with obvious warning signs to inform everyone that dangerous chemicals are stored here, and non-professionals should not approach them to ensure safety. It is also necessary to regularly check the storage situation to see if there are any abnormal conditions such as leakage and deterioration, so as to detect problems in time and deal with them properly.
This substance should be stored in a cool, dry and well-ventilated place. In a cool place, the temperature should not be too high, because high temperature can easily cause chemical reactions, or decomposition, or cause other unstable changes. The temperature should be maintained at 15 to 25 degrees Celsius, so that its chemical properties can be relatively stable.
A dry environment is also indispensable. If the moisture in the air comes into contact with 2-chloro-4,6-difluorobenzenesulfonyl chloride, it may promote its hydrolysis reaction, cause it to deteriorate, and lose its original chemical properties and functions. Therefore, the storage place must be moisture-proof, and a desiccant can be placed nearby to absorb water vapor in the air.
Well ventilated can disperse harmful gases that may be generated by the volatilization of substances in time to avoid danger caused by gas accumulation. And ventilation can maintain the fresh air in the storage environment and reduce the risk of accidents caused by high gas concentration.
Furthermore, when storing, it should be stored separately from oxidants, alkalis and other substances. Oxidants have strong oxidizing properties, or react violently with 2-chloro-4,6-difluorobenzenesulfonyl chloride; alkali substances may also react chemically with them, which will endanger storage safety. The two must be isolated and kept at a certain distance.
In addition, storage containers should also be carefully selected. Corrosion-resistant materials should be selected, such as specific glass materials or plastic containers that meet requirements, to prevent the container from being corroded, causing material leakage and causing safety accidents. And the container must be well sealed to ensure that outside air, moisture, etc. are difficult to invade.
Storage places should also be set up with obvious warning signs to inform everyone that dangerous chemicals are stored here, and non-professionals should not approach them to ensure safety. It is also necessary to regularly check the storage situation to see if there are any abnormal conditions such as leakage and deterioration, so as to detect problems in time and deal with them properly.
What is the market price of 2-chloro-4, 6-difluorobenzenesulfonyl Chloride?
2-Chloro-4,6-difluorobenzenesulfonyl chloride, this product is in the market, and its price varies from time to time, as well as with the supply and demand of the city and the amount of production.
In the past, the price of chemical industry was often told by people in the industry, or found in the bookkeeping of merchants. Today is different from the past, the information is smooth, and if you want to know the price, you can ask for it on the platform of chemical trading and the website of the industry.
If you are on the platform of chemical e-commerce, all kinds of merchants list the goods, and their prices are marked, and there are different specifications and purity. The higher the purity, the higher the price; if you buy more, there may be a discount. However, this price is not set in stone. If the price of raw materials rises recently, labor costs and freight also rise, the price of 2-chloro-4,6-difluorobenzenesulfonyl chloride will rise accordingly.
Looking at the industry exhibition, merchants gather and communicate with each other, during which the price of this product is discussed, which is also a reference for the actual price. And the newspaper and information journal of the industry association often analyze the trend of chemical prices. Here the price status of 2-chloro-4,6-difluorobenzenesulfonyl chloride can also be observed.
Or consult the distributors of chemical raw materials, who are familiar with the market and can tell the current approximate price based on their experience. However, the market situation is changing rapidly, and to obtain an accurate price, you need to consult in real time and make multiple comparisons to know the exact price of 2-chloro-4,6-diphenylfluorosulfonyl chloride on the market.
In the past, the price of chemical industry was often told by people in the industry, or found in the bookkeeping of merchants. Today is different from the past, the information is smooth, and if you want to know the price, you can ask for it on the platform of chemical trading and the website of the industry.
If you are on the platform of chemical e-commerce, all kinds of merchants list the goods, and their prices are marked, and there are different specifications and purity. The higher the purity, the higher the price; if you buy more, there may be a discount. However, this price is not set in stone. If the price of raw materials rises recently, labor costs and freight also rise, the price of 2-chloro-4,6-difluorobenzenesulfonyl chloride will rise accordingly.
Looking at the industry exhibition, merchants gather and communicate with each other, during which the price of this product is discussed, which is also a reference for the actual price. And the newspaper and information journal of the industry association often analyze the trend of chemical prices. Here the price status of 2-chloro-4,6-difluorobenzenesulfonyl chloride can also be observed.
Or consult the distributors of chemical raw materials, who are familiar with the market and can tell the current approximate price based on their experience. However, the market situation is changing rapidly, and to obtain an accurate price, you need to consult in real time and make multiple comparisons to know the exact price of 2-chloro-4,6-diphenylfluorosulfonyl chloride on the market.
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