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2-Chloro-4-(Chloromethyl)-1-Methylbenzene
Linshang Chemical
|
HS Code |
547735 |
| Chemical Formula | C8H8Cl2 |
| Molar Mass | 175.055 g/mol |
| Solubility In Water | Insoluble (aromatic chlorinated hydrocarbons are generally hydrophobic) |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone, toluene |
| Vapor Pressure | Low (as it is a relatively high - boiling liquid) |
| Flash Point | Estimated to be in the range of 80 - 100 °C (similar to related chlorinated aromatic compounds) |
As an accredited 2-Chloro-4-(Chloromethyl)-1-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 2 - chloro - 4 - (chloromethyl)-1 - methylbenzene in a sealed, labeled chemical bottle. |
| Storage | 2 - chloro - 4 - (chloromethyl)-1 - methylbenzene should be stored in a cool, dry, well - ventilated area, away from sources of ignition. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, acids, and bases to prevent chemical reactions. Ensure the storage area has proper spill - containment measures. |
| Shipping | 2 - chloro - 4 - (chloromethyl)-1 - methylbenzene is shipped in accordance with strict chemical regulations. Packed in suitable containers to prevent leakage, it's transported with care, ensuring compliance with safety and environmental requirements during transit. |
Competitive 2-Chloro-4-(Chloromethyl)-1-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365006308
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What are the chemical properties of 2-chloro-4- (chloromethyl) -1-methylbenzene?
2-Chloro-4- (chloromethyl) -1-methylbenzene, this is an organic compound. Its chemical properties are unique and of great research value.
Looking at its structure, above the benzene ring, there are chlorine atoms, chloromethyl groups and methyl groups. This structure endows the compound with many properties.
In terms of reactivity, the electron cloud density of the benzene ring changes due to the presence of chlorine atoms and chloromethyl groups. The chlorine atoms have an electron-absorbing effect, which decreases the electron cloud density of the benzene ring and weakens the electrophilic substitution reaction activity. However, the chlorine atoms in the chlorine methyl group can undergo nucleophilic substitution reactions due to their special positions. This is because in the carbon-chlorine bond, the chlorine atom has strong electronegativity, which makes the carbon atom partially positively charged and vulnerable to attack by nucleophilic reagents.
Again on its stability, due to the conjugation system of the benzene ring, the compound is endowed with certain stability. However, the chlorine methyl part is relatively active due to the presence of chlorine atoms. In case of suitable conditions, such as nucleophilic reagents, basic environments, etc., it is easy to react.
In addition, the physical properties of the compound are also related to chemical properties. Because of its chlorine atom, the relative density may be higher than that of ordinary hydrocarbon compounds. And the molecular polarity changes due to the presence of substituents, which also affects its solubility and other physical properties. In short, 2-chloro-4- (chloromethyl) -1-methylbenzene, whose chemical properties are determined by its structure, may have important applications in organic synthesis and other fields.
Looking at its structure, above the benzene ring, there are chlorine atoms, chloromethyl groups and methyl groups. This structure endows the compound with many properties.
In terms of reactivity, the electron cloud density of the benzene ring changes due to the presence of chlorine atoms and chloromethyl groups. The chlorine atoms have an electron-absorbing effect, which decreases the electron cloud density of the benzene ring and weakens the electrophilic substitution reaction activity. However, the chlorine atoms in the chlorine methyl group can undergo nucleophilic substitution reactions due to their special positions. This is because in the carbon-chlorine bond, the chlorine atom has strong electronegativity, which makes the carbon atom partially positively charged and vulnerable to attack by nucleophilic reagents.
Again on its stability, due to the conjugation system of the benzene ring, the compound is endowed with certain stability. However, the chlorine methyl part is relatively active due to the presence of chlorine atoms. In case of suitable conditions, such as nucleophilic reagents, basic environments, etc., it is easy to react.
In addition, the physical properties of the compound are also related to chemical properties. Because of its chlorine atom, the relative density may be higher than that of ordinary hydrocarbon compounds. And the molecular polarity changes due to the presence of substituents, which also affects its solubility and other physical properties. In short, 2-chloro-4- (chloromethyl) -1-methylbenzene, whose chemical properties are determined by its structure, may have important applications in organic synthesis and other fields.
What are the main uses of 2-chloro-4- (chloromethyl) -1-methylbenzene?
2-Chloro-4- (chloromethyl) -1-methylbenzene, an organic compound, has a wide range of uses and is involved in many fields.
In the field of organic synthesis, it is often used as a key intermediate. Due to its molecular structure containing chlorine atoms and chloromethyl groups, both of which have high reactivity. With the activity of chlorine atoms, nucleophilic substitution reactions can be used to interact with various nucleophiles, and then different functional groups can be introduced to construct more complex organic molecules. The activity of chloromethyl groups can also participate in many reactions, such as Friedel-Crafts alkylation reactions, which can help synthesize aromatic compounds with specific structures. For example, if you want to synthesize a certain type of pharmaceutical intermediate with specific functions, you can use this compound as a starting material, and gradually build the target molecular structure by appropriate reaction steps.
In the field of materials science, it also has certain uses. After a specific chemical reaction, it can be introduced into the main chain or side chain of polymer materials. Due to the presence of chlorine atoms and methyl groups in the molecule, it may endow polymer materials with unique properties. For example, by enhancing the chemical resistance of materials, the electronegativity of chlorine atoms is higher, which can enhance the intermolecular force, make the material structure more stable and resist chemical attack. Or change the solubility and processing properties of materials, providing more possibilities for material processing and forming.
In the field of pesticides, or an important raw material for the synthesis of new pesticides. Due to the characteristics of molecular structure, or with special biological activity to some pests and pathogens. By rational design and subsequent reaction modification, high-efficiency, low-toxicity and environmentally friendly pesticide products can be developed. For example, by modifying its structure, the effect on specific target organisms can be improved, while reducing the impact on non-target organisms, so as to achieve the purpose of precise pest control.
In the field of organic synthesis, it is often used as a key intermediate. Due to its molecular structure containing chlorine atoms and chloromethyl groups, both of which have high reactivity. With the activity of chlorine atoms, nucleophilic substitution reactions can be used to interact with various nucleophiles, and then different functional groups can be introduced to construct more complex organic molecules. The activity of chloromethyl groups can also participate in many reactions, such as Friedel-Crafts alkylation reactions, which can help synthesize aromatic compounds with specific structures. For example, if you want to synthesize a certain type of pharmaceutical intermediate with specific functions, you can use this compound as a starting material, and gradually build the target molecular structure by appropriate reaction steps.
In the field of materials science, it also has certain uses. After a specific chemical reaction, it can be introduced into the main chain or side chain of polymer materials. Due to the presence of chlorine atoms and methyl groups in the molecule, it may endow polymer materials with unique properties. For example, by enhancing the chemical resistance of materials, the electronegativity of chlorine atoms is higher, which can enhance the intermolecular force, make the material structure more stable and resist chemical attack. Or change the solubility and processing properties of materials, providing more possibilities for material processing and forming.
In the field of pesticides, or an important raw material for the synthesis of new pesticides. Due to the characteristics of molecular structure, or with special biological activity to some pests and pathogens. By rational design and subsequent reaction modification, high-efficiency, low-toxicity and environmentally friendly pesticide products can be developed. For example, by modifying its structure, the effect on specific target organisms can be improved, while reducing the impact on non-target organisms, so as to achieve the purpose of precise pest control.
What is the synthesis method of 2-chloro-4- (chloromethyl) -1-methylbenzene?
For the synthesis of 2-chloro-4- (chloromethyl) -1-methylbenzene, the general method is followed.
First, 1-methyl-2-chlorobenzene can be used. First, paraformaldehyde and hydrogen chloride are introduced under the action of appropriate catalysts, such as zinc salts. In this reaction, paraformaldehyde is depolymerized to formaldehyde, and it is added to hydrogen chloride to form chloromethanol, which then undergoes an electrophilic substitution reaction with 1-methyl-2-chlorobenzene, and chloromethyl is introduced at the para-position of the benzene ring to obtain the target product. When reacting, it is necessary to pay attention to the ratio of reaction temperature to reactant. If the temperature is too high, side reactions will occur frequently, and if the ratio is not correct, the yield will be damaged.
Second, 1-methylbenzene can also be used as the initial raw material. First, chlorine gas is used in the presence of light or an initiator to chlorinate the methyl group to obtain 1 - (chloromethyl) - 1 - methylbenzene. Subsequently, chlorine gas and iron filings or ferric chloride are used as catalysts to introduce chlorine atoms into the ortho-position of the benzene ring to obtain 2-chloro-4 - (chloromethyl) - 1 - methylbenzene. In this path, the light intensity and time have a great influence on the degree of chlorination during the light chlorination reaction, and when the benzene ring is chlorinated, the amount of catalyst and the control of the reaction conditions are related to the selectivity and yield of the reaction.
Or there may be other methods, but these two are more commonly used. During synthesis, various conditions, such as temperature, pressure, catalyst, and ratio of reactants, need to be carefully studied and fine-tuned to make the reaction smooth and obtain a product with higher yield and purity.
First, 1-methyl-2-chlorobenzene can be used. First, paraformaldehyde and hydrogen chloride are introduced under the action of appropriate catalysts, such as zinc salts. In this reaction, paraformaldehyde is depolymerized to formaldehyde, and it is added to hydrogen chloride to form chloromethanol, which then undergoes an electrophilic substitution reaction with 1-methyl-2-chlorobenzene, and chloromethyl is introduced at the para-position of the benzene ring to obtain the target product. When reacting, it is necessary to pay attention to the ratio of reaction temperature to reactant. If the temperature is too high, side reactions will occur frequently, and if the ratio is not correct, the yield will be damaged.
Second, 1-methylbenzene can also be used as the initial raw material. First, chlorine gas is used in the presence of light or an initiator to chlorinate the methyl group to obtain 1 - (chloromethyl) - 1 - methylbenzene. Subsequently, chlorine gas and iron filings or ferric chloride are used as catalysts to introduce chlorine atoms into the ortho-position of the benzene ring to obtain 2-chloro-4 - (chloromethyl) - 1 - methylbenzene. In this path, the light intensity and time have a great influence on the degree of chlorination during the light chlorination reaction, and when the benzene ring is chlorinated, the amount of catalyst and the control of the reaction conditions are related to the selectivity and yield of the reaction.
Or there may be other methods, but these two are more commonly used. During synthesis, various conditions, such as temperature, pressure, catalyst, and ratio of reactants, need to be carefully studied and fine-tuned to make the reaction smooth and obtain a product with higher yield and purity.
What are the precautions for 2-chloro-4- (chloromethyl) -1-methylbenzene during storage and transportation?
2-Chloro-4- (chloromethyl) -1-methylbenzene, this is an organic compound, and many things need to be paid attention to when storing and transporting.
Bear the brunt, because of its chemical activity, it requires strict packaging materials. Choose corrosion-resistant containers, such as special glassware or specific plastic containers, to prevent material leakage caused by packaging corrosion. Because once leaked, not only will the material be lost, but it will even pollute the environment and endanger the safety of surrounding personnel.
Second, the storage environment is crucial. It should be placed in a cool, dry and well-ventilated place. Avoid high temperatures and open flames. When the compound is heated or exposed to open flames, it may burn or even explode. And humid environments can easily induce chemical reactions and cause it to deteriorate, so it is particularly critical to keep it dry.
Furthermore, when transporting, it is necessary to follow relevant regulations and standards. Transportation vehicles need to be equipped with professional protective equipment and emergency treatment tools. Drivers and escorts should also be familiar with the characteristics of the compound and emergency treatment methods. During transportation, strive for stability, avoid bumps and violent vibrations, and prevent damage to the packaging.
In addition, whether it is stored or transported, it should be strictly marked. The name, characteristics, hazard warnings and other information of the compound should be marked in a prominent position on the package, so that relevant personnel can clearly know and take appropriate protective and emergency measures in a timely manner.
Also, the storage area should be managed by a special person to regularly check the condition of the material and the integrity of the package. If any abnormalities are found, such as signs of damage to the package or signs of material leakage, immediate measures must be taken, such as transferring the material, repairing the package, etc., and detailed records must be taken for traceability and analysis.
In short, the storage and transportation of 2-chloro-4- (chloromethyl) -1-methylbenzene requires all-round caution and must not be taken lightly to ensure the safety of personnel and the environment is not polluted.
Bear the brunt, because of its chemical activity, it requires strict packaging materials. Choose corrosion-resistant containers, such as special glassware or specific plastic containers, to prevent material leakage caused by packaging corrosion. Because once leaked, not only will the material be lost, but it will even pollute the environment and endanger the safety of surrounding personnel.
Second, the storage environment is crucial. It should be placed in a cool, dry and well-ventilated place. Avoid high temperatures and open flames. When the compound is heated or exposed to open flames, it may burn or even explode. And humid environments can easily induce chemical reactions and cause it to deteriorate, so it is particularly critical to keep it dry.
Furthermore, when transporting, it is necessary to follow relevant regulations and standards. Transportation vehicles need to be equipped with professional protective equipment and emergency treatment tools. Drivers and escorts should also be familiar with the characteristics of the compound and emergency treatment methods. During transportation, strive for stability, avoid bumps and violent vibrations, and prevent damage to the packaging.
In addition, whether it is stored or transported, it should be strictly marked. The name, characteristics, hazard warnings and other information of the compound should be marked in a prominent position on the package, so that relevant personnel can clearly know and take appropriate protective and emergency measures in a timely manner.
Also, the storage area should be managed by a special person to regularly check the condition of the material and the integrity of the package. If any abnormalities are found, such as signs of damage to the package or signs of material leakage, immediate measures must be taken, such as transferring the material, repairing the package, etc., and detailed records must be taken for traceability and analysis.
In short, the storage and transportation of 2-chloro-4- (chloromethyl) -1-methylbenzene requires all-round caution and must not be taken lightly to ensure the safety of personnel and the environment is not polluted.
What are the effects of 2-chloro-4- (chloromethyl) -1-methylbenzene on the environment and human health?
2-Chloro-4- (chloromethyl) -1-methylbenzene, this is an organic compound. Discuss its impact on the environment and human health.
In terms of the environment, if this compound is released in nature, it has certain chemical stability, is difficult to degrade rapidly, or causes accumulation in the environment. It can exist in soil, water and atmosphere, affecting ecological balance. In soil, or change soil properties, interfere with plant root absorption of nutrients, affect plant growth and development, and even cause plant toxicity, reduce the number of some species, and destroy biodiversity. In water, or cause poisoning to aquatic organisms, interfere with the physiological functions of aquatic organisms, such as affecting the respiration and reproduction of fish, and changing the structure and function of aquatic ecosystems. In the atmosphere, or participate in photochemical reactions, generate secondary pollutants, affect air quality, and cause air pollution problems.
It is related to human health, and this compound has potential hazards. Inhalation through the respiratory tract, or irritate the mucosa of the respiratory tract, causing symptoms such as cough, asthma, breathing difficulties, etc. Long-term inhalation, or damage lung function, increases the risk of respiratory diseases. If exposed to the skin, it may cause skin allergies, redness, swelling, itching, and even damage the skin barrier function, making harmful substances more likely to invade the human body. Accidental ingestion can cause gastrointestinal discomfort, such as nausea, vomiting, abdominal pain, diarrhea, and in severe cases, damage the function of organs such as the liver and kidneys. Because of its metabolism in the body or the production of toxic intermediates, it affects the normal physiological function of cells and threatens human health.
In short, 2-chloro-4- (chloromethyl) -1-methylbenzene is potentially harmful to the environment and human health. When producing, using and disposing of this compound, proper protective and management measures should be taken to reduce its adverse effects on the environment and people.
In terms of the environment, if this compound is released in nature, it has certain chemical stability, is difficult to degrade rapidly, or causes accumulation in the environment. It can exist in soil, water and atmosphere, affecting ecological balance. In soil, or change soil properties, interfere with plant root absorption of nutrients, affect plant growth and development, and even cause plant toxicity, reduce the number of some species, and destroy biodiversity. In water, or cause poisoning to aquatic organisms, interfere with the physiological functions of aquatic organisms, such as affecting the respiration and reproduction of fish, and changing the structure and function of aquatic ecosystems. In the atmosphere, or participate in photochemical reactions, generate secondary pollutants, affect air quality, and cause air pollution problems.
It is related to human health, and this compound has potential hazards. Inhalation through the respiratory tract, or irritate the mucosa of the respiratory tract, causing symptoms such as cough, asthma, breathing difficulties, etc. Long-term inhalation, or damage lung function, increases the risk of respiratory diseases. If exposed to the skin, it may cause skin allergies, redness, swelling, itching, and even damage the skin barrier function, making harmful substances more likely to invade the human body. Accidental ingestion can cause gastrointestinal discomfort, such as nausea, vomiting, abdominal pain, diarrhea, and in severe cases, damage the function of organs such as the liver and kidneys. Because of its metabolism in the body or the production of toxic intermediates, it affects the normal physiological function of cells and threatens human health.
In short, 2-chloro-4- (chloromethyl) -1-methylbenzene is potentially harmful to the environment and human health. When producing, using and disposing of this compound, proper protective and management measures should be taken to reduce its adverse effects on the environment and people.
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