Linshang Chemical
PRODUCTS
2-Chloro-4-Fluoronitrobenzene
Linshang Chemical
|
HS Code |
217458 |
| Chemical Formula | C6H3ClFNO2 |
| Molecular Weight | 175.54 |
| Appearance | Yellow to light brown solid |
| Boiling Point | Around 230 - 235 °C |
| Melting Point | 39 - 43 °C |
| Density | 1.489 g/cm³ (estimated) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Flash Point | 101.7 °C |
| Odor | Characteristic, pungent odor |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 2-Chloro-4-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 - gram bottle packaging for 2 - chloro - 4 - fluoronitrobenzene chemical. |
| Storage | 2 - Chloro - 4 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. It should be separated from oxidizing agents, reducing agents, and bases due to potential reactivity. Keep it in tightly - sealed containers to prevent leakage and exposure to air or moisture. Store in a dedicated chemical storage facility following safety regulations. |
| Shipping | 2 - chloro - 4 - fluoronitrobenzene is shipped in tightly sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring proper handling to prevent spills and maintain safety during transit. |
Competitive 2-Chloro-4-Fluoronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-4-Fluoronitrobenzene in China?
As a trusted 2-Chloro-4-Fluoronitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-4-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 2-chloro-4-fluoronitrobenzene?
2-Chloro-4-fluoronitrobenzene is also an organic compound. Its physical properties are quite impressive.
Looking at its properties, it is a white-like to light yellow crystalline powder under normal circumstances. Under sunlight, it is slightly shiny. Its melting point is moderate, about 32-34 ° C. If it is candled with fire, it will melt when heated and turn into a flowing liquid, just like the melting snow in the mountains, flowing slowly.
When it comes to the boiling point, it is about 232-234 ° C. When the temperature rises, it liquefies into gas and rises, which is the state change of matter from liquid phase to gas phase.
The density of 2-chloro-4-fluoronitrobenzene is heavier than that of water. If a small amount is placed in water, such as a stone sinking into the abyss, it falls straight down and sinks to the bottom of the water. Its solubility in water is very limited, just like the incompatibility of oil and water, it can only be slightly soluble. However, in organic solvents, such as ethanol, ether, and acetone, it shows good solubility and can be miscible with organic solvents, just like water emulsion, and it is integrated.
Its vapor pressure also has characteristics. Under a specific temperature environment, it will slowly evaporate, and a faint smell will escape in the surrounding air. It is slightly irritating. Although it is not very strong, it can still be perceived by people.
These physical properties are of great significance in chemical experiments and industrial production. Due to the characteristics of melting point and boiling point, it can provide the basis for the operation of separation and purification; and the characteristics of solubility can also help to select the appropriate reaction medium to promote the smooth progress of chemical reactions.
Looking at its properties, it is a white-like to light yellow crystalline powder under normal circumstances. Under sunlight, it is slightly shiny. Its melting point is moderate, about 32-34 ° C. If it is candled with fire, it will melt when heated and turn into a flowing liquid, just like the melting snow in the mountains, flowing slowly.
When it comes to the boiling point, it is about 232-234 ° C. When the temperature rises, it liquefies into gas and rises, which is the state change of matter from liquid phase to gas phase.
The density of 2-chloro-4-fluoronitrobenzene is heavier than that of water. If a small amount is placed in water, such as a stone sinking into the abyss, it falls straight down and sinks to the bottom of the water. Its solubility in water is very limited, just like the incompatibility of oil and water, it can only be slightly soluble. However, in organic solvents, such as ethanol, ether, and acetone, it shows good solubility and can be miscible with organic solvents, just like water emulsion, and it is integrated.
Its vapor pressure also has characteristics. Under a specific temperature environment, it will slowly evaporate, and a faint smell will escape in the surrounding air. It is slightly irritating. Although it is not very strong, it can still be perceived by people.
These physical properties are of great significance in chemical experiments and industrial production. Due to the characteristics of melting point and boiling point, it can provide the basis for the operation of separation and purification; and the characteristics of solubility can also help to select the appropriate reaction medium to promote the smooth progress of chemical reactions.
What are the main uses of 2-chloro-4-fluoronitrobenzene?
2-Chloro-4-fluoronitrobenzene has a wide range of uses in the chemical industry.
First, it is an essential material for organic synthesis. It can be used in the production of medicine. Such as the synthesis of some antibacterial and anti-inflammatory drugs, with its special chemical structure, through multi-step reaction, key groups are introduced to form molecules with specific pharmacological activities. It is also useful in the preparation of pesticides. Insecticides, herbicides, etc., with their chemical properties, can be derived from pesticide ingredients with high efficiency, low toxicity and specific mechanism of action, which protect crop growth and remove diseases and pests.
Second, it is indispensable in the field of dyes. Its structure can help generate dyes with bright colors and good fastness. After chemical modification, different chromogenic groups and chromogenic groups are connected to adapt to different fiber materials, such as cotton, linen, silk, chemical fibers, etc., so that the dye has a bright and lasting color.
Third, it has emerged in the field of materials science. It is used to prepare special polymer materials. It is polymerized with other monomers to provide unique properties of materials, such as heat resistance, chemical corrosion resistance, electrical insulation, etc. It is used in aerospace, electronic and electrical fields that require strict material properties.
Fourth, as a chemical intermediate, it can be converted into many other organic compounds through reactions such as substitution and reduction. It expands the path of organic synthesis and enriches the variety of compounds, providing a cornerstone for the diverse development of the chemical industry.
First, it is an essential material for organic synthesis. It can be used in the production of medicine. Such as the synthesis of some antibacterial and anti-inflammatory drugs, with its special chemical structure, through multi-step reaction, key groups are introduced to form molecules with specific pharmacological activities. It is also useful in the preparation of pesticides. Insecticides, herbicides, etc., with their chemical properties, can be derived from pesticide ingredients with high efficiency, low toxicity and specific mechanism of action, which protect crop growth and remove diseases and pests.
Second, it is indispensable in the field of dyes. Its structure can help generate dyes with bright colors and good fastness. After chemical modification, different chromogenic groups and chromogenic groups are connected to adapt to different fiber materials, such as cotton, linen, silk, chemical fibers, etc., so that the dye has a bright and lasting color.
Third, it has emerged in the field of materials science. It is used to prepare special polymer materials. It is polymerized with other monomers to provide unique properties of materials, such as heat resistance, chemical corrosion resistance, electrical insulation, etc. It is used in aerospace, electronic and electrical fields that require strict material properties.
Fourth, as a chemical intermediate, it can be converted into many other organic compounds through reactions such as substitution and reduction. It expands the path of organic synthesis and enriches the variety of compounds, providing a cornerstone for the diverse development of the chemical industry.
What are 2-chloro-4-fluoronitrobenzene synthesis methods?
2-Chloro-4-fluoronitrobenzene is an important intermediate in organic synthesis. There are many synthesis methods, and the common ones are as follows.
One is the halogenation reaction method. 4-fluoronitrobenzene is used as the starting material, and chlorination is carried out with chlorine gas or chlorine-containing reagents under appropriate reaction conditions. This reaction requires attention to the reaction temperature, catalyst selection and dosage. Usually iron powder, ferric chloride, etc. can be selected as catalysts. At a suitable temperature range, such as 50-80 ° C, chlorine gas slowly enters the reaction system. By controlling the flow rate of chlorine gas and reaction time, the reaction can proceed smoothly to obtain the target product 2-chloro-4-fluoronitrobenzene. However, in this process, it is necessary to properly handle the tail gas to avoid environmental pollution caused by the escape of chlorine gas.
The second is the nitrification reaction method. First, 2-chloro-4-fluorobenzene is used as the substrate, and the nitro group is introduced through the nitrification reaction. Generally, mixed acid (a mixture of nitric acid and sulfuric acid) is used as the nitrification reagent. The ratio of mixed acid, reaction temperature and time are all key factors. If the ratio of nitric acid and sulfuric acid in the mixed acid is improper, or the reaction temperature is too high, it is easy to cause side reactions such as polynitrification. Usually the reaction temperature should be controlled at 0-10 ° C, and the reaction time is about 2-4 hours. After post-treatment such as extraction and distillation, the purer 2-chloro-4-fluoronitrobenzene can be obtained.
The third is the halogen exchange reaction method. Halogen exchange reaction is carried out with 2-chloro-4-nitrohalobenzene (such as 2-chloro-4-nitrobromobenzene) and fluorinated reagents (such as potassium fluoride, etc.). This reaction usually needs to be carried out in polar aprotic solvents, such as dimethyl sulfoxide (DMSO) or N, N-dimethylformamide (DMF). The reaction temperature is relatively high, about 150-200 ° C, and a phase transfer catalyst, such as tetrabutylammonium bromide, is added to accelerate the reaction process. By this method, 2-chloro-4-fluoronitrobenzene can be effectively synthesized, but attention needs to be paid to the recovery and treatment of the solvent to reduce costs and protect the environment.
The above methods have advantages and disadvantages. In the actual synthesis, the appropriate synthesis path should be carefully selected according to the availability of raw materials, cost, product purity requirements and many other factors.
One is the halogenation reaction method. 4-fluoronitrobenzene is used as the starting material, and chlorination is carried out with chlorine gas or chlorine-containing reagents under appropriate reaction conditions. This reaction requires attention to the reaction temperature, catalyst selection and dosage. Usually iron powder, ferric chloride, etc. can be selected as catalysts. At a suitable temperature range, such as 50-80 ° C, chlorine gas slowly enters the reaction system. By controlling the flow rate of chlorine gas and reaction time, the reaction can proceed smoothly to obtain the target product 2-chloro-4-fluoronitrobenzene. However, in this process, it is necessary to properly handle the tail gas to avoid environmental pollution caused by the escape of chlorine gas.
The second is the nitrification reaction method. First, 2-chloro-4-fluorobenzene is used as the substrate, and the nitro group is introduced through the nitrification reaction. Generally, mixed acid (a mixture of nitric acid and sulfuric acid) is used as the nitrification reagent. The ratio of mixed acid, reaction temperature and time are all key factors. If the ratio of nitric acid and sulfuric acid in the mixed acid is improper, or the reaction temperature is too high, it is easy to cause side reactions such as polynitrification. Usually the reaction temperature should be controlled at 0-10 ° C, and the reaction time is about 2-4 hours. After post-treatment such as extraction and distillation, the purer 2-chloro-4-fluoronitrobenzene can be obtained.
The third is the halogen exchange reaction method. Halogen exchange reaction is carried out with 2-chloro-4-nitrohalobenzene (such as 2-chloro-4-nitrobromobenzene) and fluorinated reagents (such as potassium fluoride, etc.). This reaction usually needs to be carried out in polar aprotic solvents, such as dimethyl sulfoxide (DMSO) or N, N-dimethylformamide (DMF). The reaction temperature is relatively high, about 150-200 ° C, and a phase transfer catalyst, such as tetrabutylammonium bromide, is added to accelerate the reaction process. By this method, 2-chloro-4-fluoronitrobenzene can be effectively synthesized, but attention needs to be paid to the recovery and treatment of the solvent to reduce costs and protect the environment.
The above methods have advantages and disadvantages. In the actual synthesis, the appropriate synthesis path should be carefully selected according to the availability of raw materials, cost, product purity requirements and many other factors.
2-chloro-4-fluoronitrobenzene What are the precautions during storage and transportation?
2-Chloro-4-fluoronitrobenzene is a chemical substance, and many matters must be paid attention to during storage and transportation.
Its properties are dangerous. When storing, the first thing to do is to choose a cool, dry and well-ventilated place. This is because the substance is prone to changes due to heat. If it is in a humid place, it may react with water vapor, which will damage its quality and even cause danger. The temperature of the warehouse should be controlled within a specific range, and it should not be too high, so as not to cause safety risks.
Furthermore, it must be separated from oxidizing agents, reducing agents, alkalis and other substances. Due to its lively chemical properties, contact with their substances can easily cause severe chemical reactions, or cause disasters such as combustion and explosion. Storage should be equipped with proper fire and explosion-proof facilities, such as fire extinguishers, fire sand, etc., to prevent accidents.
As for transportation, the packaging must be solid and tight. Make sure that it is not damaged and leaked due to vibration, collision during transportation. Transport vehicles should also have corresponding safety labels and protective measures. Transport personnel must be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. Transportation routes should be planned to avoid crowded places and environmentally sensitive areas to prevent serious damage in the event of leakage.
Caution must also be taken during loading and unloading. The operator should wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to avoid direct contact with the human body. Pack and unload lightly, do not subject the package to strong impact, so as to ensure the safety of the whole transportation process.
Its properties are dangerous. When storing, the first thing to do is to choose a cool, dry and well-ventilated place. This is because the substance is prone to changes due to heat. If it is in a humid place, it may react with water vapor, which will damage its quality and even cause danger. The temperature of the warehouse should be controlled within a specific range, and it should not be too high, so as not to cause safety risks.
Furthermore, it must be separated from oxidizing agents, reducing agents, alkalis and other substances. Due to its lively chemical properties, contact with their substances can easily cause severe chemical reactions, or cause disasters such as combustion and explosion. Storage should be equipped with proper fire and explosion-proof facilities, such as fire extinguishers, fire sand, etc., to prevent accidents.
As for transportation, the packaging must be solid and tight. Make sure that it is not damaged and leaked due to vibration, collision during transportation. Transport vehicles should also have corresponding safety labels and protective measures. Transport personnel must be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. Transportation routes should be planned to avoid crowded places and environmentally sensitive areas to prevent serious damage in the event of leakage.
Caution must also be taken during loading and unloading. The operator should wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to avoid direct contact with the human body. Pack and unload lightly, do not subject the package to strong impact, so as to ensure the safety of the whole transportation process.
2-chloro-4-fluoronitrobenzene impact on the environment and human health
2-Chloro-4-fluoronitrobenzene is one of the organic compounds. It has a wide range of industrial uses, but it has several effects on the environment and human health.
As far as the environment is concerned, if this compound is released in nature, it is difficult to be rapidly decomposed by natural processes due to its chemical stability. In soil, it may cause soil pollution, affect the ecological balance of soil microorganisms, and then interfere with the absorption of nutrients by plant roots, or hinder plant growth and development, resulting in reduced crop yield. In water bodies, it may cause water quality to deteriorate and poison aquatic organisms. Exposure to this compound by aquatic organisms such as fish and shellfish may cause physiological disorders, decreased reproductive capacity, and even death, ultimately destroying the balance of aquatic ecosystems.
As for human health, 2-chloro-4-fluoronitrobenzene can invade the human body through respiratory tract, skin contact and accidental ingestion. Inhalation through the respiratory tract, or irritation of respiratory mucosa, causing cough, asthma, breathing difficulties and other symptoms. Long-term exposure to this compound environment may damage lung function, increasing the risk of respiratory diseases. If exposed to skin, it may cause skin allergies, itching, redness and swelling and other contact dermatitis symptoms. If ingested by mistake, it may be metabolized in the body, damage important organs such as liver and kidney, and affect the normal function of organs. What's more, this compound may have potential carcinogenicity, long-term exposure or increase the risk of cancer, endangering life and health. Therefore, in the production and use of 2-chloro-4-fluoronitrobenzene, strict protective measures and environmental protection measures must be taken to reduce its harm to the environment and human health.
As far as the environment is concerned, if this compound is released in nature, it is difficult to be rapidly decomposed by natural processes due to its chemical stability. In soil, it may cause soil pollution, affect the ecological balance of soil microorganisms, and then interfere with the absorption of nutrients by plant roots, or hinder plant growth and development, resulting in reduced crop yield. In water bodies, it may cause water quality to deteriorate and poison aquatic organisms. Exposure to this compound by aquatic organisms such as fish and shellfish may cause physiological disorders, decreased reproductive capacity, and even death, ultimately destroying the balance of aquatic ecosystems.
As for human health, 2-chloro-4-fluoronitrobenzene can invade the human body through respiratory tract, skin contact and accidental ingestion. Inhalation through the respiratory tract, or irritation of respiratory mucosa, causing cough, asthma, breathing difficulties and other symptoms. Long-term exposure to this compound environment may damage lung function, increasing the risk of respiratory diseases. If exposed to skin, it may cause skin allergies, itching, redness and swelling and other contact dermatitis symptoms. If ingested by mistake, it may be metabolized in the body, damage important organs such as liver and kidney, and affect the normal function of organs. What's more, this compound may have potential carcinogenicity, long-term exposure or increase the risk of cancer, endangering life and health. Therefore, in the production and use of 2-chloro-4-fluoronitrobenzene, strict protective measures and environmental protection measures must be taken to reduce its harm to the environment and human health.
Scan to WhatsApp
