2-Chloro-4-Methoxynitrobenzene
Linshang Chemical
HS Code |
907235 |
Chemical Formula | C7H6ClNO3 |
Molecular Weight | 187.58 |
Appearance | Yellow solid |
Melting Point | 82 - 84 °C |
Boiling Point | 303.5 °C at 760 mmHg |
Density | 1.387 g/cm³ |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | 137.3 °C |
Cas Number | 89-61-2 |
Odor | Characteristic |
As an accredited 2-Chloro-4-Methoxynitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 2 - chloro - 4 - methoxynitrobenzene packaged in a sealed chemical - grade bottle. |
Storage | 2 - Chloro - 4 - methoxynitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly closed container to prevent moisture absorption and leakage. Separate from incompatible substances to avoid potential reactions. This storage method helps maintain its stability and safety. |
Shipping | 2 - Chloro - 4 - methoxynitrobenzene is shipped in well - sealed containers, following strict hazardous chemical regulations. Containers are carefully labeled, and transportation ensures proper handling to prevent spills and maintain safety during transit. |
Competitive 2-Chloro-4-Methoxynitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 2-Chloro-4-Methoxynitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Bearing the brunt, it plays a significant role in the field of drug synthesis. By ingeniously modifying and transforming its structure, a variety of drug molecules with unique pharmacological activities can be prepared. For example, in the synthesis of some antibacterial drugs and drugs for the treatment of cardiovascular diseases, 2-chloro-4-methoxynitrobenzene is often used as a starting material. After many chemical reaction steps, a specific structure that fits the drug target is formed, and then the therapeutic effect is exerted.
Furthermore, it also has extraordinary performance in the field of pesticides. It can be used as an important intermediate for the synthesis of new pesticides. Through chemical synthesis, it is endowed with insecticidal, bactericidal, weeding and other characteristics to meet the needs of agricultural production for pest control and weed control. Due to its structural characteristics, it can provide specific active groups for the synthesized pesticide molecules, enhancing the effect and selectivity of pesticides on target organisms.
In addition, in the field of materials science, it can also emerge. Can be used to synthesize materials with special photoelectric properties. For example, by introducing it into the structure of polymer materials through a series of reactions, it is expected to improve the conductivity, optical absorption and emission properties of materials, etc., so as to be applied to the preparation of organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices, and to promote the progress of materials science and related technologies.
In summary, 2-chloro-4-methoxynitrobenzene, with its unique chemical structure, plays an important role in many fields such as drugs, pesticides and materials science, and is indispensable in the development of modern chemical industry and scientific research.
Looking at its morphology, at room temperature, it is mostly a solid state. Due to the intermolecular forces, the molecules are arranged in an orderly manner, so they condense into a solid state.
When it comes to color, it often appears white to light yellow, just like the subtle color change of the early morning sunlight. The formation of this color is related to the distribution and transition of electron clouds of each atom in the molecular structure.
Smell the smell, with a special aromatic aroma, but this smell is not pure fragrance, slightly with the unique irritation of chemical substances, and the smell can make people feel its chemical characteristics.
As for the melting point, it is within a specific range. This is determined by the intermolecular force and lattice energy, which is one of the important physical constants for the identification of this substance.
Its solubility is also an important property. In common organic solvents, such as ethanol, ether, etc., it can have a certain solubility. This is because the molecules of organic solvents and 2-chloro-4-methoxy nitrobenzene molecules can form interactions such as van der Waals force and hydrogen bonds to help them dissolve. In water, the solubility is very small, because the polarity of water molecules and the molecular polarity of the compound are quite different, it is difficult to form an effective interaction, so it is not easily soluble.
In addition, density is also one end of its physical properties, and there is a specific value. This value reflects the mass of its unit volume and is related to the molecular structure and the type and number of constituent atoms.
In summary, the physical properties, morphology, color, odor, melting point, solubility, density, etc. of 2-chloro-4-methoxynitrobenzene are determined by its molecular structure, and each property has its own unique significance in chemical research and application.
Let's talk about the chlorine atom first, which has a certain activity and can initiate a nucleophilic substitution reaction. Under appropriate conditions, the nucleophilic tester can attack the carbon atom connected to the chlorine atom and replace the chlorine atom. For example, in an alkaline environment and there are suitable nucleophilic reagents, chlorine can be replaced by hydroxyl groups, amino groups, etc.
Methoxy group as the power supply radical can enhance the electron cloud density of the benzene ring, which has an impact on the activity of the reaction check point on the benzene ring. It increases the electron cloud density of the ortho and para-site of the benzene ring, which is conducive to the electrophilic substitution reaction to occur in the ortho and para-site. However, in this compound, the nitro group and the chlorine atom also exist, and the interaction of each group makes the judgment of the reactivity more complicated.
Nitro is a strong electron-absorbing group, which significantly reduces the electron cloud density of the benzene ring, and decreases the electrophilic substitution reaction activity of the benzene ring. At the same time, the presence of nitro groups can affect the activity of other groups. For example, it can reduce the electron cloud density of the ortho and para-site of the chlorine atom, so that the activity of the chlorine atom is different from that of the chlorine atom in simple chlorobenzene.
Overall, 2-chloro-4- Under different conditions, various reactions can occur, such as nucleophilic substitution, electrophilic substitution, etc. It can still maintain a certain degree of stability at room temperature and pressure without the action of special reagents. However, under suitable reaction conditions and reagents, it will exhibit active chemical properties and participate in a variety of chemical reactions.
Furthermore, the nitro group can be introduced into the benzene ring containing chlorine and methoxy groups through the nitration reaction. Generally speaking, the mixed acid of concentrated nitric acid and concentrated sulfuric acid is used as the nitrifying agent, and the reaction temperature, time and proportion of reactants are precisely controlled to make the nitro group suitable for the check point substitution of the benzene ring, so that 2-chloro-4-methoxy nitrobenzene is obtained.
Another way is to carry out nucleophilic substitution reaction with halogenated aromatics and methoxylating reagents. Select suitable halogenated nitrobenzene, such as 2-chloro-4-nitrochlorobenzene, and methoxylating reagents, such as sodium methoxide, in a suitable solvent, heat the reaction, methoxy can replace chlorine atoms, and successfully synthesize the target product. In the reaction, the polarity of the solvent, the reaction temperature and the concentration of the reagent all have a great influence on the reaction process and yield.
Although there are many synthesis methods, each has its own advantages and disadvantages. When operating, it is necessary to comprehensively consider the availability of raw materials, the difficulty of controlling the reaction conditions, the separation and purification of the product and many other factors, and carefully choose the appropriate synthesis path to achieve the desired synthesis effect.
The first priority is safety. This substance may be toxic, irritating, or even risk of explosion. When storing, it is advisable to choose a cool, dry and well-ventilated place, away from fire and heat sources, to prevent decomposition by heat and cause danger. It needs to be stored separately from oxidants, reducing agents, acids, bases, etc., and must not be mixed to avoid chemical reactions.
In terms of packaging, it must be tight to ensure that there is no risk of leakage. The packaging materials used should meet relevant standards and be resistant to corrosion of the substance. During transportation, it should also be loaded securely to prevent collisions and bumps, so as not to damage the packaging.
Furthermore, operators must be professionally trained to be familiar with its characteristics and safe operating procedures. The storage area should be equipped with suitable containment materials to prevent leakage and can be dealt with in time. Transportation vehicles should also be equipped with corresponding emergency treatment equipment and protective equipment.
In short, when dealing with 2-chloro-4-methoxynitrobenzene, regardless of storage or transportation, relevant norms and safety guidelines must be strictly followed to ensure the safety of personnel and the environment from harm.

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