Linshang Chemical
PRODUCTS
2-Chloro-4-Methyl-1-Nitrobenzene
Linshang Chemical
|
HS Code |
288606 |
| Chemical Formula | C7H6ClNO2 |
| Appearance | Yellow - brown solid |
| Boiling Point | 246 - 248 °C |
| Melting Point | 34 - 37 °C |
| Density | 1.336 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Flash Point | 106.6 °C |
| Odor | Characteristic aromatic odor |
| Vapor Pressure | Low vapor pressure |
As an accredited 2-Chloro-4-Methyl-1-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2 - chloro - 4 - methyl - 1 - nitrobenzene packaged in a sealed, corrosion - resistant bottle. |
| Storage | 2 - Chloro - 4 - methyl - 1 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions. |
| Shipping | 2 - Chloro - 4 - methyl - 1 - nitrobenzene should be shipped in tightly sealed, corrosion - resistant containers. Label packages clearly as a hazardous chemical. Ensure compliance with all relevant transportation regulations for safe shipping. |
Competitive 2-Chloro-4-Methyl-1-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-4-Methyl-1-Nitrobenzene in China?
As a trusted 2-Chloro-4-Methyl-1-Nitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-4-Methyl-1-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-chloro-4-methyl-1-nitrobenzene?
2-%-4-methyl-1-naphthyl ether, this substance is used for a wide range of purposes. It is often used as an important part of the synthesis of specific compounds. Due to the chemical properties of compounds, it has certain active groups, which can be cleverly transformed by chemical reactions, resulting in the production of biocompatible molecules, helping to cure diseases.
In the materials industry, 2-%-4-methyl-1-naphthyl ether also has extraordinary performance. It can be used as a raw material for optical materials, carefully synthesized, and gives materials special optical properties. For example, in the research of optical diodes (OLEDs), the materials derived from this material base may be able to improve the optical efficiency, color resolution and quality of the device, and the technology can be further improved.
Furthermore, in the fragrance industry, it also has a place. With its own special flavor, it can be blended into the fragrance formula, adding a special fragrance to the fragrance. It is used in the fields of perfumes, chemicals and food additives to enhance the sensory quality of the product.
Of course, 2-%-4-methyl-1-naphthyl ether plays an indispensable role in a variety of technologies, such as materials, fragrances, etc., and promotes the innovation of various fields.
In the materials industry, 2-%-4-methyl-1-naphthyl ether also has extraordinary performance. It can be used as a raw material for optical materials, carefully synthesized, and gives materials special optical properties. For example, in the research of optical diodes (OLEDs), the materials derived from this material base may be able to improve the optical efficiency, color resolution and quality of the device, and the technology can be further improved.
Furthermore, in the fragrance industry, it also has a place. With its own special flavor, it can be blended into the fragrance formula, adding a special fragrance to the fragrance. It is used in the fields of perfumes, chemicals and food additives to enhance the sensory quality of the product.
Of course, 2-%-4-methyl-1-naphthyl ether plays an indispensable role in a variety of technologies, such as materials, fragrances, etc., and promotes the innovation of various fields.
What are the physical properties of 2-chloro-4-methyl-1-nitrobenzene?
The 2-%-4-methyl-1-naphthyl ether is one of the most common compounds. Its physical properties are very specific.
< This property is advantageous in the reaction of the reaction, for the solution of the reaction, or in the separation process, the use of the same solubility, to the purpose of separation.
The boiling rate also has a specific value, the degree of boiling is increased to the boiling rate, and 2-% 4-methyl-1-naphthyl ether is reduced from the liquid. The boiling level reflects the weak molecular force. In addition, the density is also one of its physical properties. The specific density value has a significant impact on the mixing system, the separation of matter, and the storage system.
These physical properties, such as external properties, melting properties, solubility, boiling properties, density, etc., are mutually beneficial and each has its own uses. They are essential for in-depth understanding of the properties of 2-% -4-methyl-1-naphthyl ether, preparation, and application.
< This property is advantageous in the reaction of the reaction, for the solution of the reaction, or in the separation process, the use of the same solubility, to the purpose of separation.
The boiling rate also has a specific value, the degree of boiling is increased to the boiling rate, and 2-% 4-methyl-1-naphthyl ether is reduced from the liquid. The boiling level reflects the weak molecular force. In addition, the density is also one of its physical properties. The specific density value has a significant impact on the mixing system, the separation of matter, and the storage system.
These physical properties, such as external properties, melting properties, solubility, boiling properties, density, etc., are mutually beneficial and each has its own uses. They are essential for in-depth understanding of the properties of 2-% -4-methyl-1-naphthyl ether, preparation, and application.
What are the chemical properties of 2-chloro-4-methyl-1-nitrobenzene?
The chemical properties of 2-%-4-methyl-1-naphthyl acetylene are particularly high. In this compound, the groups such as methyl and naphthyl acetylene coexist and interact with each other to give their properties.
As far as its physical properties are concerned, 2-%-4-methyl-1-naphthyl acetylene is often reduced or solidified, because of the existence of a certain force on its molecules, causing it to have a specific melting effect. However, the properties of this compound need to be determined according to the accuracy.
In terms of chemical activity, the alkylene of the naphthyl acetylene part makes it have a certain anti-activity. The alkylene can be added to the anti-reaction, such as pigments, acids, etc. In case of oxidation, the alkynyl group may also be oxidized to form a phase oxide. The presence of methyl groups affects the sub-cloud of the molecule, or changes the sub-cloud density of the naphthalene, which affects the substitution and anti-activity of the naphthalene. In addition, the atom may seem ordinary, but under specific anti-atom conditions, it may be reversed by atomic migration, etc., to integrate the anti-process of the molecule.
This compound may have a certain amount of power in the field of synthesis, and can be used in the process of synthesis. However, the in-depth investigation of its chemical properties still needs to be done by more researchers.
As far as its physical properties are concerned, 2-%-4-methyl-1-naphthyl acetylene is often reduced or solidified, because of the existence of a certain force on its molecules, causing it to have a specific melting effect. However, the properties of this compound need to be determined according to the accuracy.
In terms of chemical activity, the alkylene of the naphthyl acetylene part makes it have a certain anti-activity. The alkylene can be added to the anti-reaction, such as pigments, acids, etc. In case of oxidation, the alkynyl group may also be oxidized to form a phase oxide. The presence of methyl groups affects the sub-cloud of the molecule, or changes the sub-cloud density of the naphthalene, which affects the substitution and anti-activity of the naphthalene. In addition, the atom may seem ordinary, but under specific anti-atom conditions, it may be reversed by atomic migration, etc., to integrate the anti-process of the molecule.
This compound may have a certain amount of power in the field of synthesis, and can be used in the process of synthesis. However, the in-depth investigation of its chemical properties still needs to be done by more researchers.
What are the synthesis methods of 2-chloro-4-methyl-1-nitrobenzene?
To prepare 2-bromo-4-methyl-1-nitrobenzene, the following method can be used.
First, 4-methylaniline is used as the starting material. Shilling 4-methylaniline interacts with acetic anhydride to obtain N-acetyl-4-methylaniline. This step aims to protect the amino group because it is more active under subsequent reaction conditions. Then, N-acetyl-4-methylaniline is reacted with bromine in an appropriate solvent such as glacial acetic acid. Due to the fact that the acetamide group is an ortho-and para-site locator, and the steric hindrance, the bromine atom is mainly substituted in the ortho-site of the amino group to obtain N-acetyl-2-bromo-4-methylaniline. Finally, the product is hydrolyzed with an acid or base to deacetyl and then nitrified. Since the amino group is re-exposed after hydrolysis, it is a strong donor group, and the localization effect causes the nitro group to mainly enter the para-site of the amino group, thereby obtaining 2-bromo-4-methyl-1-nitrobenzene.
Second, p-xylene is used as the starting material. It is brominated first. Because methyl is an ortho-and para-localization group, a suitable catalyst such as iron bromide can be selected to replace the bromine atom in the ortho-methyl position to obtain 2-bromo-4-methyl benzene. In this reaction, due to the superposition of the localization effect of the two methyl groups, the proportion of ortho-substitution products is relatively high. Subsequently, 2-bromo-4-methyl benzene is nitrified. Under the localization of methyl, the nitro group can enter the para-position of methyl to generate 2-bromo-4-methyl-1-nitrobenzene. However, it should be noted that the nitrification reaction conditions are more severe, and factors such as reaction temperature may be controlled to prevent excessive nitrification or other side reactions.
Third, use 2-methylphenol as raw material. First, the phenolic hydroxyl group is properly protected, such as reacting with chloromethyl methyl ether to form a methoxymethyl ether protecting group. Next, the protected compound is brominated. Since the phenolic hydroxyl group is protected, its localization effect is less affected, and methyl is an ortho-and para-site locator. Bromine atoms can be replaced by methyl ortho-sites to obtain 2-bromo-4-methyl-1 - (methoxymethoxy) benzene. After that, the product is nitrified, and the nitro group enters the counterposition under the positioning of the methyl group. Finally, the protective group is removed by an appropriate method, the phenolic hydroxyl group is restored, and then the hydroxyl group is converted into nitro group through diazotization, nitrogen release and other reactions to obtain the target product 2-bromo-4-methyl-1-nitrobenzene. This route has relatively many steps, but it has its advantages for the selection of raw materials and the selective control of the product under specific conditions.
First, 4-methylaniline is used as the starting material. Shilling 4-methylaniline interacts with acetic anhydride to obtain N-acetyl-4-methylaniline. This step aims to protect the amino group because it is more active under subsequent reaction conditions. Then, N-acetyl-4-methylaniline is reacted with bromine in an appropriate solvent such as glacial acetic acid. Due to the fact that the acetamide group is an ortho-and para-site locator, and the steric hindrance, the bromine atom is mainly substituted in the ortho-site of the amino group to obtain N-acetyl-2-bromo-4-methylaniline. Finally, the product is hydrolyzed with an acid or base to deacetyl and then nitrified. Since the amino group is re-exposed after hydrolysis, it is a strong donor group, and the localization effect causes the nitro group to mainly enter the para-site of the amino group, thereby obtaining 2-bromo-4-methyl-1-nitrobenzene.
Second, p-xylene is used as the starting material. It is brominated first. Because methyl is an ortho-and para-localization group, a suitable catalyst such as iron bromide can be selected to replace the bromine atom in the ortho-methyl position to obtain 2-bromo-4-methyl benzene. In this reaction, due to the superposition of the localization effect of the two methyl groups, the proportion of ortho-substitution products is relatively high. Subsequently, 2-bromo-4-methyl benzene is nitrified. Under the localization of methyl, the nitro group can enter the para-position of methyl to generate 2-bromo-4-methyl-1-nitrobenzene. However, it should be noted that the nitrification reaction conditions are more severe, and factors such as reaction temperature may be controlled to prevent excessive nitrification or other side reactions.
Third, use 2-methylphenol as raw material. First, the phenolic hydroxyl group is properly protected, such as reacting with chloromethyl methyl ether to form a methoxymethyl ether protecting group. Next, the protected compound is brominated. Since the phenolic hydroxyl group is protected, its localization effect is less affected, and methyl is an ortho-and para-site locator. Bromine atoms can be replaced by methyl ortho-sites to obtain 2-bromo-4-methyl-1 - (methoxymethoxy) benzene. After that, the product is nitrified, and the nitro group enters the counterposition under the positioning of the methyl group. Finally, the protective group is removed by an appropriate method, the phenolic hydroxyl group is restored, and then the hydroxyl group is converted into nitro group through diazotization, nitrogen release and other reactions to obtain the target product 2-bromo-4-methyl-1-nitrobenzene. This route has relatively many steps, but it has its advantages for the selection of raw materials and the selective control of the product under specific conditions.
What are the precautions for using 2-chloro-4-methyl-1-nitrobenzene?
If 2-% 4-methyl-1-naphthyl ether is used, it is necessary to pay attention to the situation and not ignore it.
This substance is a chemical compound with certain chemical activity. First, it is necessary to avoid open flames and high temperatures. Because of its flammability, in case of open flames, high temperatures, it may ignite or even explode, endangering the safety of personal and surrounding objects.
Furthermore, the operation is necessary to ensure good health. Because of its irritating effect, or the respiratory tract, eyes, etc., it is easy to cause damage to the body and even harm health. Operators should take precautions against clothing, wear eyes, masks, etc., to ensure their own safety.
In addition, it is also necessary to be careful if it is stored. It should be placed in the environment, dry and good, and oxidized, etc. Due to the connection of oxidation, or the reaction of intensification, accidents can occur.
In addition, before use, it is necessary to familiarize the operation process with the emergency preparation method. Once there is an accident such as leakage, it can be managed according to a certain plan, and the harm can be minimized. The amount of use also needs to be precisely controlled, and it should be selected according to the needs of the buyer, which is not only to prevent waves, but also to avoid the risk of not being produced due to the amount. In addition, when using this product, many people should pay attention to it to ensure safety and convenient use.
This substance is a chemical compound with certain chemical activity. First, it is necessary to avoid open flames and high temperatures. Because of its flammability, in case of open flames, high temperatures, it may ignite or even explode, endangering the safety of personal and surrounding objects.
Furthermore, the operation is necessary to ensure good health. Because of its irritating effect, or the respiratory tract, eyes, etc., it is easy to cause damage to the body and even harm health. Operators should take precautions against clothing, wear eyes, masks, etc., to ensure their own safety.
In addition, it is also necessary to be careful if it is stored. It should be placed in the environment, dry and good, and oxidized, etc. Due to the connection of oxidation, or the reaction of intensification, accidents can occur.
In addition, before use, it is necessary to familiarize the operation process with the emergency preparation method. Once there is an accident such as leakage, it can be managed according to a certain plan, and the harm can be minimized. The amount of use also needs to be precisely controlled, and it should be selected according to the needs of the buyer, which is not only to prevent waves, but also to avoid the risk of not being produced due to the amount. In addition, when using this product, many people should pay attention to it to ensure safety and convenient use.
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