Linshang Chemical
PRODUCTS
2-Chloro-5-Amino-2',4'-Dimethyl Benzene Sulfonamide
Linshang Chemical
|
HS Code |
788881 |
| Chemical Formula | C10H13ClN2O2S |
| Molar Mass | 260.74 g/mol |
| Appearance | Solid (predicted) |
| Solubility In Water | Low solubility (predicted) |
| Logp | Estimated value: 2.5 - 3.5 (predicted) |
| Stability | Stable under normal conditions (predicted) |
As an accredited 2-Chloro-5-Amino-2',4'-Dimethyl Benzene Sulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle packaging for 2 - chloro - 5 - amino - 2',4'-dimethyl Benzene Sulfonamide. |
| Storage | 2 - chloro - 5 - amino - 2',4' - dimethyl Benzene Sulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and direct sunlight. Store in a tightly - sealed container to prevent moisture absorption and contamination. Separate from oxidizing agents, acids, and bases to avoid chemical reactions. |
| Shipping | 2 - chloro - 5 - amino - 2',4' - dimethyl Benzene Sulfonamide is shipped in tightly sealed containers. It's transported under conditions that avoid heat, moisture, and incompatible substances to ensure safe and proper delivery. |
Competitive 2-Chloro-5-Amino-2',4'-Dimethyl Benzene Sulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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What is the chemical structure of 2-chloro-5-amino-2 ', 4' -dimethyl Benzene Sulfonamide?
2-Chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide, according to its name, this is a kind of organic compound. Its structure starts from the benzene ring. The benzene ring, a six-membered carbon ring, has special stability and electron cloud distribution.
Above the benzene ring, the chlorine atom occupies two positions. Chlorine, a halogen element, has high electronegativity. When connected to the benzene ring, it can cause the electron cloud density distribution of the benzene ring to change abnormally, which affects the reactivity and physical properties of the compound.
Five-membered, aminoamide. The amino group is a nucleophilic group with lone pair electrons, which often increases the density of the electron cloud in the ortho-para of the benzene ring, and is prone to electrophilic substitution reactions at these positions.
As for 2 ', 4' -dimethyl, this indicates that the other benzene ring connected to the benzene ring (or can be regarded as a part of the structure of the benzene ring derivative) has methyl additions at the ortho (2 'position) and meta (4' position) of the carbon atom connected to the main benzene ring. Methyl is the power supply group, which can increase the electron cloud density of the benzene ring, and also has an effect on the polarity, solubility, and reactivity of the whole molecule.
Looking at the sulfonamide part again, its structure is -SO 2O NH The sulfonyl-SO 2O -has strong electron-absorbing properties and is connected to the amino group to form a sulfonamide functional group. This functional group endows compounds with various chemical properties. In the fields of medicine and pesticides, it often has special biological activities due to its ability to form hydrogen bonds with targets in organisms.
Overall, the chemical structure of 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide determines its unique physicochemical properties and potential application directions due to the synergy and interaction of each group.
Above the benzene ring, the chlorine atom occupies two positions. Chlorine, a halogen element, has high electronegativity. When connected to the benzene ring, it can cause the electron cloud density distribution of the benzene ring to change abnormally, which affects the reactivity and physical properties of the compound.
Five-membered, aminoamide. The amino group is a nucleophilic group with lone pair electrons, which often increases the density of the electron cloud in the ortho-para of the benzene ring, and is prone to electrophilic substitution reactions at these positions.
As for 2 ', 4' -dimethyl, this indicates that the other benzene ring connected to the benzene ring (or can be regarded as a part of the structure of the benzene ring derivative) has methyl additions at the ortho (2 'position) and meta (4' position) of the carbon atom connected to the main benzene ring. Methyl is the power supply group, which can increase the electron cloud density of the benzene ring, and also has an effect on the polarity, solubility, and reactivity of the whole molecule.
Looking at the sulfonamide part again, its structure is -SO 2O NH The sulfonyl-SO 2O -has strong electron-absorbing properties and is connected to the amino group to form a sulfonamide functional group. This functional group endows compounds with various chemical properties. In the fields of medicine and pesticides, it often has special biological activities due to its ability to form hydrogen bonds with targets in organisms.
Overall, the chemical structure of 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide determines its unique physicochemical properties and potential application directions due to the synergy and interaction of each group.
What are the main uses of 2-chloro-5-amino-2 ', 4' -dimethyl Benzene Sulfonamide?
2-Chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide, an organic compound, has important uses in many fields.
In the field of medicine, it can be used as a key intermediate in drug synthesis. The creation of many drugs requires this compound as a starting material, and through a series of subsequent chemical transformations, complex drug molecules with specific pharmacological activities are constructed. For example, in the development of some antibacterial drugs, its chemical structure can provide a key framework for the synthesis of molecules with antibacterial properties, enabling the precise design and synthesis of drugs that have inhibitory or killing effects on specific pathogens.
In the field of pesticides, 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide also plays an important role. It can be used as an important component in the synthesis of new pesticides. After rational design and modification, it gives pesticides such as insecticidal, bactericidal or weeding effects. Due to its structural characteristics, it may exhibit high-efficiency and specific biological activities against specific pests, bacteria or weeds, thereby improving the control effect of pesticides, reducing the adverse effects on the environment and harming non-target organisms.
In the field of materials science, this compound may be used to synthesize materials with special functions. The sulfonamide group, chlorine atom, amino group and other functional groups it contains can participate in the polymerization reaction or surface modification process of materials. For example, in the preparation of some high-performance polymer materials, the introduction of this compound structural unit may improve the physical and chemical properties of the material, such as improving the stability and solubility of the material or imparting specific optical and electrical properties to the material, so as to meet the needs of different fields for special properties of the material.
In addition, in the field of chemical research, 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide, as an organic compound with a unique structure, provides an important object for theoretical research in organic synthetic chemistry, medicinal chemistry and other disciplines. Researchers can enrich their theoretical knowledge of organic chemistry, expand their synthesis methodologies, and lay the foundation for the creation and performance optimization of more novel compounds by in-depth exploration of their reaction properties, structure, and activity.
In the field of medicine, it can be used as a key intermediate in drug synthesis. The creation of many drugs requires this compound as a starting material, and through a series of subsequent chemical transformations, complex drug molecules with specific pharmacological activities are constructed. For example, in the development of some antibacterial drugs, its chemical structure can provide a key framework for the synthesis of molecules with antibacterial properties, enabling the precise design and synthesis of drugs that have inhibitory or killing effects on specific pathogens.
In the field of pesticides, 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide also plays an important role. It can be used as an important component in the synthesis of new pesticides. After rational design and modification, it gives pesticides such as insecticidal, bactericidal or weeding effects. Due to its structural characteristics, it may exhibit high-efficiency and specific biological activities against specific pests, bacteria or weeds, thereby improving the control effect of pesticides, reducing the adverse effects on the environment and harming non-target organisms.
In the field of materials science, this compound may be used to synthesize materials with special functions. The sulfonamide group, chlorine atom, amino group and other functional groups it contains can participate in the polymerization reaction or surface modification process of materials. For example, in the preparation of some high-performance polymer materials, the introduction of this compound structural unit may improve the physical and chemical properties of the material, such as improving the stability and solubility of the material or imparting specific optical and electrical properties to the material, so as to meet the needs of different fields for special properties of the material.
In addition, in the field of chemical research, 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide, as an organic compound with a unique structure, provides an important object for theoretical research in organic synthetic chemistry, medicinal chemistry and other disciplines. Researchers can enrich their theoretical knowledge of organic chemistry, expand their synthesis methodologies, and lay the foundation for the creation and performance optimization of more novel compounds by in-depth exploration of their reaction properties, structure, and activity.
What are the physical properties of 2-chloro-5-amino-2 ', 4' -dimethyl Benzene Sulfonamide?
2-Chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide, this is an organic compound. Its physical properties are unique. Under normal temperature and pressure, it is usually solid, mostly white or off-white crystalline powder, which is easy to store and transport.
Looking at its melting point, it is about a certain temperature range, which is of great significance for identification and purity determination. Due to the existence of specific groups in the molecular structure, its solubility is unique. The degree of solubility in water is limited, but in some organic solvents, such as ethanol, acetone, etc., it shows good solubility. This property has a great impact on the separation and purification steps in organic synthesis and drug preparation processes.
Its density is also one of the important physical properties. Although the specific value may vary slightly due to the measurement conditions, it is relatively stable. The appearance of the compound is crystalline, and the crystal form is regular, reflecting the order of molecular arrangement. In addition, its stability is good. Under conventional conditions, the chemical structure is not easy to change, and it can be stored for a long time without significant change in properties. However, under extreme conditions such as strong acid, strong base or high temperature, the structure may be damaged, triggering chemical reactions.
The above physical properties are widely used in organic synthesis, drug development and other fields. For example, in drug development, suitable dosage forms can be screened according to their solubility, and reasonable production and storage conditions can be formulated according to their melting point and stability to help create new drugs. In the field of organic synthesis, these properties can be used to optimize reaction conditions and enhance product purity and yield.
Looking at its melting point, it is about a certain temperature range, which is of great significance for identification and purity determination. Due to the existence of specific groups in the molecular structure, its solubility is unique. The degree of solubility in water is limited, but in some organic solvents, such as ethanol, acetone, etc., it shows good solubility. This property has a great impact on the separation and purification steps in organic synthesis and drug preparation processes.
Its density is also one of the important physical properties. Although the specific value may vary slightly due to the measurement conditions, it is relatively stable. The appearance of the compound is crystalline, and the crystal form is regular, reflecting the order of molecular arrangement. In addition, its stability is good. Under conventional conditions, the chemical structure is not easy to change, and it can be stored for a long time without significant change in properties. However, under extreme conditions such as strong acid, strong base or high temperature, the structure may be damaged, triggering chemical reactions.
The above physical properties are widely used in organic synthesis, drug development and other fields. For example, in drug development, suitable dosage forms can be screened according to their solubility, and reasonable production and storage conditions can be formulated according to their melting point and stability to help create new drugs. In the field of organic synthesis, these properties can be used to optimize reaction conditions and enhance product purity and yield.
What are the synthesis methods of 2-chloro-5-amino-2 ', 4' -dimethyl Benzene Sulfonamide?
There are various methods for the synthesis of 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide.
First, chlorine atoms can be introduced through a halogenation reaction from a suitable starting material. First, take a benzene derivative with a suitable substituent. Under specific reaction conditions, use a halogenating agent, such as a chlorine-containing halogenating agent, to halogenate the benzene ring at a specific position at a suitable temperature and in the presence of a catalyst, and precisely obtain a chlorine-containing intermediate. This step requires attention to the control of reaction conditions, such as high or low temperature and the amount of catalyst used, which can affect the halogenation position and reaction yield.
Then, add an amino group through an amination reaction. Select a suitable amination reagent and react with chlorine-containing intermediates in the presence of suitable solvents, bases and other additives. In this process, the polarity of the solvent, the strength and dosage of the base have a great influence on the reaction process and the purity of the product. At the same time, the selectivity of the reaction needs to be considered to avoid amination at non-target locations.
Second, another strategy can be considered. First construct the basic structure of benzenesulfonamide, and then introduce chlorine atoms with amino groups and dimethyl substituents in turn. First react with benzenesulfonyl chloride with suitable amine compounds to generate benzenesulfonamide derivatives. After that, the halogenation and amination reaction is carried out, and the chlorine atom and amino group are introduced at the predetermined position. This strategy requires attention to the influence of each step on the existing functional groups, and protection and de-protection measures are taken if necessary to prevent unnecessary side reactions.
Or, you can try to start from the compound containing the desired partial substituent and achieve it through a series of functional group conversion and ligation reactions. For example, the benzene derivative containing dimethyl is selected first, and the sulfonamide group, chlorine atom and amino group are introduced in sequence through a multi-step reaction. This approach requires familiarity with the mechanism and conditions of each step of the reaction, and rational planning of the reaction sequence in order to efficiently obtain the target product 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide.
First, chlorine atoms can be introduced through a halogenation reaction from a suitable starting material. First, take a benzene derivative with a suitable substituent. Under specific reaction conditions, use a halogenating agent, such as a chlorine-containing halogenating agent, to halogenate the benzene ring at a specific position at a suitable temperature and in the presence of a catalyst, and precisely obtain a chlorine-containing intermediate. This step requires attention to the control of reaction conditions, such as high or low temperature and the amount of catalyst used, which can affect the halogenation position and reaction yield.
Then, add an amino group through an amination reaction. Select a suitable amination reagent and react with chlorine-containing intermediates in the presence of suitable solvents, bases and other additives. In this process, the polarity of the solvent, the strength and dosage of the base have a great influence on the reaction process and the purity of the product. At the same time, the selectivity of the reaction needs to be considered to avoid amination at non-target locations.
Second, another strategy can be considered. First construct the basic structure of benzenesulfonamide, and then introduce chlorine atoms with amino groups and dimethyl substituents in turn. First react with benzenesulfonyl chloride with suitable amine compounds to generate benzenesulfonamide derivatives. After that, the halogenation and amination reaction is carried out, and the chlorine atom and amino group are introduced at the predetermined position. This strategy requires attention to the influence of each step on the existing functional groups, and protection and de-protection measures are taken if necessary to prevent unnecessary side reactions.
Or, you can try to start from the compound containing the desired partial substituent and achieve it through a series of functional group conversion and ligation reactions. For example, the benzene derivative containing dimethyl is selected first, and the sulfonamide group, chlorine atom and amino group are introduced in sequence through a multi-step reaction. This approach requires familiarity with the mechanism and conditions of each step of the reaction, and rational planning of the reaction sequence in order to efficiently obtain the target product 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide.
What are the precautions for using 2-chloro-5-amino-2 ', 4' -dimethyl Benzene Sulfonamide?
When using 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide, many things should be paid attention to.
First, safety is the top priority. This compound may be toxic and irritating, touching the skin, eyes, or causing burns and allergies; if inhaled or ingested, it may endanger health or even life. Therefore, when taking it, be sure to wear protective clothing, such as lab clothes, gloves, and protective glasses and masks to prevent it from coming into contact with the body. After operation, rinse hands and exposed skin with plenty of water.
Second, the chemical properties also need to be investigated in detail. 2-Chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide reacts under specific conditions or with other chemicals. Therefore, before use, it is necessary to be familiar with its chemical properties and avoid mixing with incompatible substances to prevent dangerous reactions such as explosions and toxic gases. When storing, it should also be placed in a suitable environment according to its properties, away from fire sources, heat sources and oxidants.
Furthermore, accurate weighing and use are essential. According to experimental or production needs, accurately weigh the required amount, and do not increase or decrease it at will. Excessive use may cause waste, and may increase the complexity of the reaction, resulting in unnecessary by-products; insufficient dosage may cause the reaction to fail to achieve the desired effect.
Repeated, waste disposal should not be underestimated. The remaining 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide and its reaction products after use must not be discarded at will. It must be collected in accordance with relevant regulations and handed over to professional institutions for treatment to avoid polluting the environment and endangering the ecology.
In conclusion, when using 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide, care must be taken to ensure personal safety, smooth experimentation or production, and no damage to the environment.
First, safety is the top priority. This compound may be toxic and irritating, touching the skin, eyes, or causing burns and allergies; if inhaled or ingested, it may endanger health or even life. Therefore, when taking it, be sure to wear protective clothing, such as lab clothes, gloves, and protective glasses and masks to prevent it from coming into contact with the body. After operation, rinse hands and exposed skin with plenty of water.
Second, the chemical properties also need to be investigated in detail. 2-Chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide reacts under specific conditions or with other chemicals. Therefore, before use, it is necessary to be familiar with its chemical properties and avoid mixing with incompatible substances to prevent dangerous reactions such as explosions and toxic gases. When storing, it should also be placed in a suitable environment according to its properties, away from fire sources, heat sources and oxidants.
Furthermore, accurate weighing and use are essential. According to experimental or production needs, accurately weigh the required amount, and do not increase or decrease it at will. Excessive use may cause waste, and may increase the complexity of the reaction, resulting in unnecessary by-products; insufficient dosage may cause the reaction to fail to achieve the desired effect.
Repeated, waste disposal should not be underestimated. The remaining 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide and its reaction products after use must not be discarded at will. It must be collected in accordance with relevant regulations and handed over to professional institutions for treatment to avoid polluting the environment and endangering the ecology.
In conclusion, when using 2-chloro-5-amino-2 ', 4' -dimethylbenzenesulfonamide, care must be taken to ensure personal safety, smooth experimentation or production, and no damage to the environment.
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