Linshang Chemical
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2-Chloro-5-Cyanonitrobenzene
Linshang Chemical
|
HS Code |
383082 |
| Chemical Formula | C7H3ClN2O2 |
| Molar Mass | 182.56 g/mol |
| Appearance | Solid |
| Color | Yellowish |
| Odor | Typical organic chemical odor |
| Melting Point | 106 - 109 °C |
| Boiling Point | Decomposes before boiling |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, chloroform |
| Density | 1.49 g/cm³ (estimated) |
| Stability | Stable under normal conditions but can react with strong oxidizing and reducing agents |
| Hazard Class | Toxic, harmful to the environment |
As an accredited 2-Chloro-5-Cyanonitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 25 - kg drum packaging for 2 - chloro - 5 - cyanonitrobenzene chemical. |
| Storage | 2 - Chloro - 5 - cyanonitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage and vapor release. Store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to avoid potential chemical reactions. |
| Shipping | 2 - chloro - 5 - cyanonitrobenzene is a hazardous chemical. It should be shipped in accordance with strict regulations, using appropriate containers to prevent leakage. Special handling during transit ensures safety from potential risks. |
Competitive 2-Chloro-5-Cyanonitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-5-Cyanonitrobenzene in China?
As a trusted 2-Chloro-5-Cyanonitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-5-Cyanonitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-chloro-5-cyanonitrobenzene?
2-Chloro-5-cyanonitrobenzene has a wide range of uses. In the field of medicine, it is often a key intermediate for the synthesis of many special drugs. Due to its specific chemical structure, it can be converted into molecules with unique pharmacological activities through ingenious reactions, which is helpful for disease treatment and drug development.
In the manufacture of pesticides, it also plays an important role. It can be used as a raw material to synthesize highly efficient pesticides, fungicides and other pesticide products. Its chemical properties enable it to effectively resist pests and diseases, ensure the growth of crops, and improve the yield and quality of agricultural products.
In the dye industry, 2-chloro-5-cyanonitrobenzene is also indispensable. With its unique structure, it can synthesize dyes with bright colors and good stability, which are widely used in textile, printing and dyeing and other industries to endow fabrics with rich colors.
In addition, in the field of organic synthesis, as an important intermediate, it provides starting materials for the synthesis of many complex organic compounds. Through various chemical reactions, various chemical structures are constructed to promote the development of organic synthetic chemistry. In short, 2-chloro-5-cyanonitrobenzene is of great value in many industrial fields and has far-reaching impact on the development of related industries.
In the manufacture of pesticides, it also plays an important role. It can be used as a raw material to synthesize highly efficient pesticides, fungicides and other pesticide products. Its chemical properties enable it to effectively resist pests and diseases, ensure the growth of crops, and improve the yield and quality of agricultural products.
In the dye industry, 2-chloro-5-cyanonitrobenzene is also indispensable. With its unique structure, it can synthesize dyes with bright colors and good stability, which are widely used in textile, printing and dyeing and other industries to endow fabrics with rich colors.
In addition, in the field of organic synthesis, as an important intermediate, it provides starting materials for the synthesis of many complex organic compounds. Through various chemical reactions, various chemical structures are constructed to promote the development of organic synthetic chemistry. In short, 2-chloro-5-cyanonitrobenzene is of great value in many industrial fields and has far-reaching impact on the development of related industries.
What are the physical properties of 2-chloro-5-cyanonitrobenzene?
2-Chloro-5-cyanonitrobenzene is also an organic compound. Its physical properties are quite important, let me tell you in detail.
Looking at its appearance, it often shows a crystalline powder like white to light yellow, which can be used as an important characterization when identifying this substance. Its melting point is also a key physical property, which is about a specific temperature range. Because the exact melting point is affected by many factors, such as sample purity, the approximate range can be followed. The determination of the melting point is very useful in identifying and judging the purity of this substance.
Furthermore, the solubility of this substance also has characteristics. In organic solvents, such as some common aromatic hydrocarbons and halogenated hydrocarbon solvents, it can exhibit a certain solubility. This property is of great application value in chemical synthesis, separation and purification processes. Knowing its solubility can make a reasonable choice of suitable solvents to achieve the desired reaction or separation purpose.
As for its density, although it is not very easy to intuitively perceive, it is also indispensable in the material accounting and equipment design of chemical production. Accurate density values help to accurately plan the material ratio of the reaction system and calculate the volume of the equipment, which is related to the stability and efficiency of the production process.
In addition, the volatility of this substance is low, and it is not easy to evaporate to the gas phase in a large amount under normal temperature and pressure. This property makes it possible to reduce material loss and environmental pollution caused by volatilization during storage and operation, and also reduce related safety risks, which is of great significance in practical application scenarios.
In summary, the physical properties of 2-chloro-5-cyanonitrobenzene, such as appearance, melting point, solubility, density and volatility, play their own unique and important roles in the research and development, production and application of the chemical industry.
Looking at its appearance, it often shows a crystalline powder like white to light yellow, which can be used as an important characterization when identifying this substance. Its melting point is also a key physical property, which is about a specific temperature range. Because the exact melting point is affected by many factors, such as sample purity, the approximate range can be followed. The determination of the melting point is very useful in identifying and judging the purity of this substance.
Furthermore, the solubility of this substance also has characteristics. In organic solvents, such as some common aromatic hydrocarbons and halogenated hydrocarbon solvents, it can exhibit a certain solubility. This property is of great application value in chemical synthesis, separation and purification processes. Knowing its solubility can make a reasonable choice of suitable solvents to achieve the desired reaction or separation purpose.
As for its density, although it is not very easy to intuitively perceive, it is also indispensable in the material accounting and equipment design of chemical production. Accurate density values help to accurately plan the material ratio of the reaction system and calculate the volume of the equipment, which is related to the stability and efficiency of the production process.
In addition, the volatility of this substance is low, and it is not easy to evaporate to the gas phase in a large amount under normal temperature and pressure. This property makes it possible to reduce material loss and environmental pollution caused by volatilization during storage and operation, and also reduce related safety risks, which is of great significance in practical application scenarios.
In summary, the physical properties of 2-chloro-5-cyanonitrobenzene, such as appearance, melting point, solubility, density and volatility, play their own unique and important roles in the research and development, production and application of the chemical industry.
Is 2-chloro-5-cyanonitrobenzene chemically stable?
The chemical stability of 2-chloro-5-cyanonitrobenzene depends on its structural characteristics and the environment in which it is located. This substance has chlorine atoms, cyano groups and nitro groups on the benzene ring. Although chlorine atoms have certain electronegativity, they can reduce the electron cloud density of the benzene ring slightly, but their impact on the overall stability is limited. Cyanyl, with its carbon-nitrogen triple bond structure, is quite stable, and it also adds structural stability to the benzene ring. Nitro is not the same. The nitrogen-oxygen double bond in the nitro group is rich in electron attraction and strongly absorbs electrons, resulting in a significant reduction in the electron cloud density of the benzene ring, making the benzene ring more vulnerable to attack by nucleophiles.
If it is at room temperature and pressure without the action of special chemical reagents, 2-chloro-5-cyanonitrobenzene is still stable. However, in the case of strong reducing agents, the nitro group may be reduced. If it is treated with a mixed system of iron and hydrochloric acid, the nitro group can be gradually converted into an amino group. In the case of nucleophilic reagents, such as sodium alcohol, etc., the electron cloud density of the benzene ring is reduced due to the influence of the nitro group, and the chlorine atom can be replaced by the nucleophilic group, and the cyano group or hydrolyzed to the carboxyl group under specific conditions.
In summary, the stability of 2-chloro-5-cyanonitrobenzene is not absolute, and it is relatively stable at room temperature and pressure without special reagents. However, under a specific chemical environment, due to the characteristics of each functional group, it is easy to chemically react, and the stability is lost.
If it is at room temperature and pressure without the action of special chemical reagents, 2-chloro-5-cyanonitrobenzene is still stable. However, in the case of strong reducing agents, the nitro group may be reduced. If it is treated with a mixed system of iron and hydrochloric acid, the nitro group can be gradually converted into an amino group. In the case of nucleophilic reagents, such as sodium alcohol, etc., the electron cloud density of the benzene ring is reduced due to the influence of the nitro group, and the chlorine atom can be replaced by the nucleophilic group, and the cyano group or hydrolyzed to the carboxyl group under specific conditions.
In summary, the stability of 2-chloro-5-cyanonitrobenzene is not absolute, and it is relatively stable at room temperature and pressure without special reagents. However, under a specific chemical environment, due to the characteristics of each functional group, it is easy to chemically react, and the stability is lost.
What are the preparation methods of 2-chloro-5-cyanonitrobenzene?
There are several common methods for preparing 2-chloro-5-cyanonitrobenzene.
First, 2-chloro-5-nitrobenzoic acid is used as the starting material. First, 2-chloro-5-nitrobenzoic acid is co-heated with thionyl chloride to cause an acylation reaction to obtain 2-chloro-5-nitrobenzoyl chloride. This reaction needs to be carried out at an appropriate temperature and protected by inert gas to avoid side reactions. Subsequently, 2-chloro-5-nitrobenzoyl chloride is reacted with sodium cyanide or potassium cyanide in an organic solvent. Under the action of a suitable catalyst, after the nucleophilic substitution process, 2-chloro-5-cyanonitrobenzene is obtained. In this path, the amount and reaction conditions of thionyl chloride should be paid attention to in the acylation step to ensure the complete reaction; when nucleophilic substitution, the amount of cyanide and reaction temperature should be controlled to prevent overreaction.
Second, 2-chloro-5-nitrotoluene is used as the starting material. First, it is oxidized in a suitable oxidant, such as potassium dichromate-sulfuric acid system, to obtain 2-chloro-5-nitrobenzoic acid. After that, the steps are the same as those using 2-chloro-5-nitrobenzoic acid as the raw material, first acyl chloride, and then react with cyanide to obtain the target product. However, in this process, the oxidation step needs to strictly control the conditions to avoid excessive oxidation, and pay attention to the safety and post-treatment of oxidants such as potassium dichromate.
Third, 2-chloro-1-nitro-4-methylbenzene is used as the raw material. First, it is nitrified. Under the action of appropriate nitrifying reagents such as nitric acid-sulfuric acid mixed acid, the nitro group can be introduced in a specific temperature range to obtain 2-chloro-5-nitro-1-methylbenzene. Then the methyl group is oxidized, such as using an oxidizing agent such as potassium permanganate to oxidize to a carboxyl group to obtain 2-chloro-5-nitrobenzoic acid. Subsequent acylation and cyanide reaction are used to obtain 2-chloro-5-cyanonitrobenzene. In this route, the nitrification reaction should pay attention to the ratio of nitric acid to sulfuric acid and the reaction temperature to ensure the accurate introduction of nitro groups; the oxidation step should also control the conditions to avoid affecting other groups.
First, 2-chloro-5-nitrobenzoic acid is used as the starting material. First, 2-chloro-5-nitrobenzoic acid is co-heated with thionyl chloride to cause an acylation reaction to obtain 2-chloro-5-nitrobenzoyl chloride. This reaction needs to be carried out at an appropriate temperature and protected by inert gas to avoid side reactions. Subsequently, 2-chloro-5-nitrobenzoyl chloride is reacted with sodium cyanide or potassium cyanide in an organic solvent. Under the action of a suitable catalyst, after the nucleophilic substitution process, 2-chloro-5-cyanonitrobenzene is obtained. In this path, the amount and reaction conditions of thionyl chloride should be paid attention to in the acylation step to ensure the complete reaction; when nucleophilic substitution, the amount of cyanide and reaction temperature should be controlled to prevent overreaction.
Second, 2-chloro-5-nitrotoluene is used as the starting material. First, it is oxidized in a suitable oxidant, such as potassium dichromate-sulfuric acid system, to obtain 2-chloro-5-nitrobenzoic acid. After that, the steps are the same as those using 2-chloro-5-nitrobenzoic acid as the raw material, first acyl chloride, and then react with cyanide to obtain the target product. However, in this process, the oxidation step needs to strictly control the conditions to avoid excessive oxidation, and pay attention to the safety and post-treatment of oxidants such as potassium dichromate.
Third, 2-chloro-1-nitro-4-methylbenzene is used as the raw material. First, it is nitrified. Under the action of appropriate nitrifying reagents such as nitric acid-sulfuric acid mixed acid, the nitro group can be introduced in a specific temperature range to obtain 2-chloro-5-nitro-1-methylbenzene. Then the methyl group is oxidized, such as using an oxidizing agent such as potassium permanganate to oxidize to a carboxyl group to obtain 2-chloro-5-nitrobenzoic acid. Subsequent acylation and cyanide reaction are used to obtain 2-chloro-5-cyanonitrobenzene. In this route, the nitrification reaction should pay attention to the ratio of nitric acid to sulfuric acid and the reaction temperature to ensure the accurate introduction of nitro groups; the oxidation step should also control the conditions to avoid affecting other groups.
2-chloro-5-cyanonitrobenzene need to pay attention to when storing and transporting
2-Chloro-5-cyanonitrobenzene is an important raw material for organic synthesis. During storage and transportation, many matters need to be paid attention to.
Let's talk about storage first. This substance has certain chemical activity and potential danger, so it should be stored in a cool and ventilated warehouse. If the temperature is too high, it is easy to accelerate chemical reactions or cause danger, so the warehouse temperature should be strictly controlled and not too high. Because it is also sensitive to light, it should be avoided and can be stored in a shaded container. Furthermore, it must be stored separately from oxidants, reducing agents, acids, bases, etc., and must not be mixed. Contact with these substances may cause severe chemical reactions, causing serious consequences such as fire and explosion. And the storage area should be equipped with suitable materials to contain leaks in case of leakage, which can be dealt with in time to avoid greater harm.
As for transportation, ensure that the packaging is complete and well sealed before transportation. Packaging materials should be able to effectively prevent leakage, resist external physical shocks, and ensure the stability of substances during transportation. During transportation, vehicles should be driven on smooth roads to avoid bumps and vibrations to prevent package damage. And transportation tools should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. Escort personnel should also be familiar with the nature of this substance and emergency treatment methods, and pay close attention to the condition of the goods during transportation. If a leak occurs during transportation, do not panic. According to the established emergency plan, take prompt measures to evacuate people and prevent the spread of pollution.
The storage and transportation of 2-chloro-5-cyanonitrobenzene is related to safety and the environment, and all aspects should not be ignored. It must be operated in accordance with norms to ensure foolproof operation.
Let's talk about storage first. This substance has certain chemical activity and potential danger, so it should be stored in a cool and ventilated warehouse. If the temperature is too high, it is easy to accelerate chemical reactions or cause danger, so the warehouse temperature should be strictly controlled and not too high. Because it is also sensitive to light, it should be avoided and can be stored in a shaded container. Furthermore, it must be stored separately from oxidants, reducing agents, acids, bases, etc., and must not be mixed. Contact with these substances may cause severe chemical reactions, causing serious consequences such as fire and explosion. And the storage area should be equipped with suitable materials to contain leaks in case of leakage, which can be dealt with in time to avoid greater harm.
As for transportation, ensure that the packaging is complete and well sealed before transportation. Packaging materials should be able to effectively prevent leakage, resist external physical shocks, and ensure the stability of substances during transportation. During transportation, vehicles should be driven on smooth roads to avoid bumps and vibrations to prevent package damage. And transportation tools should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. Escort personnel should also be familiar with the nature of this substance and emergency treatment methods, and pay close attention to the condition of the goods during transportation. If a leak occurs during transportation, do not panic. According to the established emergency plan, take prompt measures to evacuate people and prevent the spread of pollution.
The storage and transportation of 2-chloro-5-cyanonitrobenzene is related to safety and the environment, and all aspects should not be ignored. It must be operated in accordance with norms to ensure foolproof operation.
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