Linshang Chemical
PRODUCTS
2-Chloro-5-Fluoronitrobenzene
Linshang Chemical
|
HS Code |
172798 |
| Chemical Formula | C6H3ClFNO2 |
| Appearance | Yellow to light brown solid |
| Boiling Point | 233 - 235 °C |
| Melting Point | 37 - 41 °C |
| Density | 1.493 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
| Flash Point | 104 °C |
| Vapor Pressure | Low at room temperature |
As an accredited 2-Chloro-5-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 25 kg drum packaging for 2 - chloro - 5 - fluoronitrobenzene chemical. |
| Storage | 2 - Chloro - 5 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions. |
| Shipping | 2 - chloro - 5 - fluoronitrobenzene is shipped in tightly sealed, corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, ensuring proper labeling and handling to prevent spills and ensure transportation safety. |
Competitive 2-Chloro-5-Fluoronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-5-Fluoronitrobenzene in China?
As a trusted 2-Chloro-5-Fluoronitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-5-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-chloro-5-fluoronitrobenzene?
2-Chloro-5-fluoronitrobenzene is an important intermediate in organic synthesis. Its main uses cover a wide range of fields.
In the synthesis of medicine, it can be used as a key raw material to prepare a variety of specific drugs. Such as antibacterial and antiviral drugs, 2-chloro-5-fluoronitrobenzene can be converted into compounds with specific pharmacological activities through a series of exquisite chemical reactions, escorting human health. In the construction of drug molecular structure, it relies on its own unique chemical functional groups to ingeniously introduce specific groups to endow drugs with precise therapeutic effects.
In the process of pesticide creation, it is also an indispensable component. After rational design and synthesis, high-efficiency and low-toxicity pesticides can be prepared. Such pesticides can effectively resist crop diseases and insect pests and ensure a bumper crop harvest. For example, they can be converted into insecticides and fungicides that target specific pests or bacteria. By virtue of their structural characteristics, they can precisely act on target organisms, reduce the impact on the environment and non-target organisms, and achieve sustainable agricultural development.
In the field of dye synthesis, 2-chloro-5-fluoronitrobenzene plays an important role. Through the chemical reactions it participates in, colorful and high-performance dyes can be synthesized. These dyes are widely used in textile, printing and dyeing industries, giving fabrics brilliant color and good color fastness, satisfying people's pursuit of textile beauty and quality.
In addition, in the field of materials science, there are also potential uses. Or through specific processes, organic materials with special properties, such as photoelectric materials, can be prepared to provide a material basis for the development of emerging technologies.
In summary, 2-chloro-5-fluoronitrobenzene has a wide range of uses and is of great value in many industries such as chemical industry, medicine, agriculture, etc., promoting technological innovation and development in various fields.
In the synthesis of medicine, it can be used as a key raw material to prepare a variety of specific drugs. Such as antibacterial and antiviral drugs, 2-chloro-5-fluoronitrobenzene can be converted into compounds with specific pharmacological activities through a series of exquisite chemical reactions, escorting human health. In the construction of drug molecular structure, it relies on its own unique chemical functional groups to ingeniously introduce specific groups to endow drugs with precise therapeutic effects.
In the process of pesticide creation, it is also an indispensable component. After rational design and synthesis, high-efficiency and low-toxicity pesticides can be prepared. Such pesticides can effectively resist crop diseases and insect pests and ensure a bumper crop harvest. For example, they can be converted into insecticides and fungicides that target specific pests or bacteria. By virtue of their structural characteristics, they can precisely act on target organisms, reduce the impact on the environment and non-target organisms, and achieve sustainable agricultural development.
In the field of dye synthesis, 2-chloro-5-fluoronitrobenzene plays an important role. Through the chemical reactions it participates in, colorful and high-performance dyes can be synthesized. These dyes are widely used in textile, printing and dyeing industries, giving fabrics brilliant color and good color fastness, satisfying people's pursuit of textile beauty and quality.
In addition, in the field of materials science, there are also potential uses. Or through specific processes, organic materials with special properties, such as photoelectric materials, can be prepared to provide a material basis for the development of emerging technologies.
In summary, 2-chloro-5-fluoronitrobenzene has a wide range of uses and is of great value in many industries such as chemical industry, medicine, agriculture, etc., promoting technological innovation and development in various fields.
What are the physical properties of 2-chloro-5-fluoronitrobenzene?
2-Chloro-5-fluoronitrobenzene is a kind of organic compound. It has unique physical properties and is widely used in the field of chemistry.
In terms of its physical properties, 2-chloro-5-fluoronitrobenzene is mostly solid at room temperature, and its color may be light yellow to light brown. Due to the existence of chlorine, fluorine and nitro groups in the molecular structure, it affects its light absorption and reflection. Its melting point and boiling point are also determined by intermolecular forces. The melting point is about [X] ° C, and the boiling point is about [X] ° C. This melting point boiling point value is derived from the chemical bond energy between atoms in the molecule, and the interaction between Van der Waals forces and hydrogen bonds between molecules.
Furthermore, the density of 2-chloro-5-fluoronitrobenzene is larger than that of water, about [X] g/cm ³, due to the increase in the weight of chlorine and fluorine in the molecule. Its solubility is also an important property. It has a certain solubility in common organic solvents such as ethanol and ether, and its organic molecular structure is similar to that of organic solvents. However, in water, the solubility is very small, and it is difficult to form effective intermolecular forces due to the large difference between molecular polarity and water molecular polarity.
And because its molecules contain chlorine, fluorine, nitro and other functional groups, it has a certain stability. However, in the event of high temperature, open flame or strong oxidizing agent, there is also a potential danger, or a violent reaction. It needs to be properly stored and used to prevent accidents.
In terms of its physical properties, 2-chloro-5-fluoronitrobenzene is mostly solid at room temperature, and its color may be light yellow to light brown. Due to the existence of chlorine, fluorine and nitro groups in the molecular structure, it affects its light absorption and reflection. Its melting point and boiling point are also determined by intermolecular forces. The melting point is about [X] ° C, and the boiling point is about [X] ° C. This melting point boiling point value is derived from the chemical bond energy between atoms in the molecule, and the interaction between Van der Waals forces and hydrogen bonds between molecules.
Furthermore, the density of 2-chloro-5-fluoronitrobenzene is larger than that of water, about [X] g/cm ³, due to the increase in the weight of chlorine and fluorine in the molecule. Its solubility is also an important property. It has a certain solubility in common organic solvents such as ethanol and ether, and its organic molecular structure is similar to that of organic solvents. However, in water, the solubility is very small, and it is difficult to form effective intermolecular forces due to the large difference between molecular polarity and water molecular polarity.
And because its molecules contain chlorine, fluorine, nitro and other functional groups, it has a certain stability. However, in the event of high temperature, open flame or strong oxidizing agent, there is also a potential danger, or a violent reaction. It needs to be properly stored and used to prevent accidents.
What are 2-chloro-5-fluoronitrobenzene synthesis methods?
2-Chloro-5-fluoronitrobenzene is an important intermediate in organic synthesis. There are several common methods for its synthesis.
One is halogenation. The corresponding benzene derivative is used as the starting material, and the nitro group is first introduced through nitration reaction, and then halogenated. If 5-fluoronitrobenzene is used as the substrate, 2-chloro-5-fluoronitrobenzene can be obtained under appropriate halogenation reagents, such as chlorine-containing halogenating agents and suitable reaction conditions. In this halogenation step, the appropriate catalyst, temperature and reaction time need to be selected. If the halogenating agent is chlorine, iron powder or iron trichloride is often used as a catalyst, and the reaction is carried out in an appropriate solvent and temperature is controlled to obtain a higher yield.
The second is the fluorination method. The chlorine-containing nitrobenzene compounds are first prepared, and then fluorine atoms are introduced through the fluorination reaction. For example, 2-chloro-5-nitrobenzene is used as a raw material, and a suitable fluorination reagent, such as potassium fluoride, is heated in a specific reaction medium in the presence of a phase transfer catalyst. In this process, the choice and dosage of the phase transfer catalyst are very critical, which can promote the transfer of anions and cations in the reaction system, speed up the reaction process, and improve the yield of the product.
The third is the direct nitrohalogenation method. Using benzene or its simple derivatives as the starting material, the nitrification and halogenation reactions are completed in one step by rationally designing the reaction conditions. This method requires precise control of the reaction conditions, such as the proportion of reactants, reaction temperature, reaction time, and the catalyst used. For example, in the presence of a specific mixed acid system and halogenating agent, the benzene derivative is directly reacted, and the reaction parameters are skillfully adjusted, which is expected to directly generate 2-chloro-5-fluoronitrobenzene. However, this method requires strict reaction conditions and is difficult to operate. It requires fine control to be successful.
One is halogenation. The corresponding benzene derivative is used as the starting material, and the nitro group is first introduced through nitration reaction, and then halogenated. If 5-fluoronitrobenzene is used as the substrate, 2-chloro-5-fluoronitrobenzene can be obtained under appropriate halogenation reagents, such as chlorine-containing halogenating agents and suitable reaction conditions. In this halogenation step, the appropriate catalyst, temperature and reaction time need to be selected. If the halogenating agent is chlorine, iron powder or iron trichloride is often used as a catalyst, and the reaction is carried out in an appropriate solvent and temperature is controlled to obtain a higher yield.
The second is the fluorination method. The chlorine-containing nitrobenzene compounds are first prepared, and then fluorine atoms are introduced through the fluorination reaction. For example, 2-chloro-5-nitrobenzene is used as a raw material, and a suitable fluorination reagent, such as potassium fluoride, is heated in a specific reaction medium in the presence of a phase transfer catalyst. In this process, the choice and dosage of the phase transfer catalyst are very critical, which can promote the transfer of anions and cations in the reaction system, speed up the reaction process, and improve the yield of the product.
The third is the direct nitrohalogenation method. Using benzene or its simple derivatives as the starting material, the nitrification and halogenation reactions are completed in one step by rationally designing the reaction conditions. This method requires precise control of the reaction conditions, such as the proportion of reactants, reaction temperature, reaction time, and the catalyst used. For example, in the presence of a specific mixed acid system and halogenating agent, the benzene derivative is directly reacted, and the reaction parameters are skillfully adjusted, which is expected to directly generate 2-chloro-5-fluoronitrobenzene. However, this method requires strict reaction conditions and is difficult to operate. It requires fine control to be successful.
2-chloro-5-fluoronitrobenzene What are the precautions during storage and transportation?
2-Chloro-5-fluoronitrobenzene is an organic compound. During storage and transportation, many matters need to be paid attention to.
When storing, choose the first environment. It must be placed in a cool and ventilated warehouse, away from fires and heat sources. This material may be at risk of combustion and explosion due to heat or open flame. The temperature of the warehouse should be strictly controlled, not too high, to prevent changes in the properties of the compound.
Furthermore, it should be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with them can easily cause chemical reactions or cause dangerous accidents.
Packaging is also crucial. Be sure to ensure that the package is well sealed and there is no risk of leakage. If the package is damaged, 2-chloro-5-fluoronitrobenzene will escape, which will not only pollute the environment, but also pose a threat to the health of surrounding personnel.
During transportation, the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During driving, it is necessary to protect against sun exposure, rain and high temperature.
When loading and unloading, operators should wear appropriate protective equipment, such as gas masks, chemical protective clothing, etc., be careful, pack and unload lightly to avoid damage to packaging and containers. During transportation, do not stop in densely populated areas or busy areas.
In this way, the safety of 2-chloro-5-fluoronitrobenzene during storage and transportation is guaranteed, and accidents are avoided.
When storing, choose the first environment. It must be placed in a cool and ventilated warehouse, away from fires and heat sources. This material may be at risk of combustion and explosion due to heat or open flame. The temperature of the warehouse should be strictly controlled, not too high, to prevent changes in the properties of the compound.
Furthermore, it should be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with them can easily cause chemical reactions or cause dangerous accidents.
Packaging is also crucial. Be sure to ensure that the package is well sealed and there is no risk of leakage. If the package is damaged, 2-chloro-5-fluoronitrobenzene will escape, which will not only pollute the environment, but also pose a threat to the health of surrounding personnel.
During transportation, the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During driving, it is necessary to protect against sun exposure, rain and high temperature.
When loading and unloading, operators should wear appropriate protective equipment, such as gas masks, chemical protective clothing, etc., be careful, pack and unload lightly to avoid damage to packaging and containers. During transportation, do not stop in densely populated areas or busy areas.
In this way, the safety of 2-chloro-5-fluoronitrobenzene during storage and transportation is guaranteed, and accidents are avoided.
2-chloro-5-fluoronitrobenzene impact on the environment and human health
2-Chloro-5-fluoronitrobenzene is also an organic compound. It has many effects on the environment and human health.
As far as the environment is concerned, if this substance is released in nature, it can remain in the soil and water body for a long time because of its chemical stability and difficulty in being decomposed by microorganisms. In the soil, it may cause soil quality deterioration, affect the growth of vegetation, prevent its absorption of nutrients, or cause abnormal plant development, short leaves and yellow plants, and greatly reduce yield. In the water body, it can cause water pollution and endanger the survival of aquatic organisms. Fish may suffer from damage to their gills, breathing difficulties, and even death; algae growth may also be disturbed, disrupting the balance of water ecosystems, causing increased eutrophication of water bodies, and foul odor in water quality.
As for human health, 2-chloro-5-fluoronitrobenzene is toxic. If people enter the body through breathing, skin contact, or accidental ingestion, it can damage multiple organ systems. Breathing its vapor can irritate the respiratory tract, causing cough, asthma, breathing difficulties, long-term exposure or lung diseases. Skin contact can cause skin allergies, redness, swelling, itching, rash, severe or ulceration. Eating it by mistake can damage the digestive system, cause nausea, vomiting, abdominal pain, diarrhea, etc., and even damage important organs such as the liver and kidneys, affecting their normal functions, such as liver detoxification, impaired renal excretion, and accumulation of toxins in the body, endangering life. In addition, it may be potentially carcinogenic, and long-term exposure or increased risk of cancer.
From this point of view, the production, use and disposal of 2-chloro-5-fluoronitrobenzene should be treated with caution to prevent it from harming the environment and human health.
As far as the environment is concerned, if this substance is released in nature, it can remain in the soil and water body for a long time because of its chemical stability and difficulty in being decomposed by microorganisms. In the soil, it may cause soil quality deterioration, affect the growth of vegetation, prevent its absorption of nutrients, or cause abnormal plant development, short leaves and yellow plants, and greatly reduce yield. In the water body, it can cause water pollution and endanger the survival of aquatic organisms. Fish may suffer from damage to their gills, breathing difficulties, and even death; algae growth may also be disturbed, disrupting the balance of water ecosystems, causing increased eutrophication of water bodies, and foul odor in water quality.
As for human health, 2-chloro-5-fluoronitrobenzene is toxic. If people enter the body through breathing, skin contact, or accidental ingestion, it can damage multiple organ systems. Breathing its vapor can irritate the respiratory tract, causing cough, asthma, breathing difficulties, long-term exposure or lung diseases. Skin contact can cause skin allergies, redness, swelling, itching, rash, severe or ulceration. Eating it by mistake can damage the digestive system, cause nausea, vomiting, abdominal pain, diarrhea, etc., and even damage important organs such as the liver and kidneys, affecting their normal functions, such as liver detoxification, impaired renal excretion, and accumulation of toxins in the body, endangering life. In addition, it may be potentially carcinogenic, and long-term exposure or increased risk of cancer.
From this point of view, the production, use and disposal of 2-chloro-5-fluoronitrobenzene should be treated with caution to prevent it from harming the environment and human health.
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