Linshang Chemical
PRODUCTS
2-Chloro-5-Hydroxybenzene Carboxylic Acid
Linshang Chemical
|
HS Code |
265915 |
| Name | 2-Chloro-5-Hydroxybenzene Carboxylic Acid |
| Molecular Formula | C7H5ClO3 |
| Molar Mass | 172.57 g/mol |
| Appearance | Solid (usually white or off - white) |
| Solubility In Water | Slightly soluble |
| Melting Point | 198 - 201 °C |
| Boiling Point | Decomposes before boiling |
| Acidity | Weak acid, pKa around 3 - 4 |
| Odor | Odorless or very faint odor |
| Density | Approx. 1.55 g/cm³ |
As an accredited 2-Chloro-5-Hydroxybenzene Carboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottles of 2 - chloro - 5 - hydroxybenzoic acid, tightly sealed for safety. |
| Storage | 2 - Chloro - 5 - hydroxybenzoic acid should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contamination. Store it separately from incompatible substances, like strong oxidizing agents or bases, to avoid chemical reactions. Use a well - ventilated storage area to minimize the risk of fume accumulation. |
| Shipping | 2 - chloro - 5 - hydroxybenzoic acid is shipped in well - sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations is ensured, with proper labeling indicating its nature to safeguard handlers and the environment during transit. |
Competitive 2-Chloro-5-Hydroxybenzene Carboxylic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chloro-5-Hydroxybenzene Carboxylic Acid in China?
As a trusted 2-Chloro-5-Hydroxybenzene Carboxylic Acid manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chloro-5-Hydroxybenzene Carboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-chloro-5-hydroxybenzoic acid?
2-% -5-fluorobenzoic acid is one of the most important chemical compounds. Its main uses are described in this article.
In this field, this compound is of great importance. It can be used as a starting material for the synthesis of polymers. The researchers have developed anti-tumor compounds, often 2-% -5-fluorobenzoic acid. From a series of exquisite chemical reactions, it can be used to create molecules with specific biological activities, which are used to prevent the proliferation of tumor cells, prevent their apoptosis, and treat cancer.
In this field, there are also extraordinary performances. It can be used to synthesize high-efficiency and low-toxicity products such as bacteria. This product can effectively eliminate crop diseases and damage, but the environmental pollution is minimal, and the toxicity to humans and animals is also low, which is beneficial to the sustainable development of the environment.
Furthermore, in the field of materials science, 2-% fluorobenzoic acid also has its place. It can be used in the synthesis of polymer materials with special properties, such as polymers with resistance to corrosion and chemical corrosion. This material can be used in high-end applications such as aerospace and electronics to meet the demanding requirements of high-performance materials.
Therefore, 2-% fluorobenzoic acid has an important position in chemical engineering and related technology exhibitions due to its important uses in the fields of engineering, engineering and materials.
In this field, this compound is of great importance. It can be used as a starting material for the synthesis of polymers. The researchers have developed anti-tumor compounds, often 2-% -5-fluorobenzoic acid. From a series of exquisite chemical reactions, it can be used to create molecules with specific biological activities, which are used to prevent the proliferation of tumor cells, prevent their apoptosis, and treat cancer.
In this field, there are also extraordinary performances. It can be used to synthesize high-efficiency and low-toxicity products such as bacteria. This product can effectively eliminate crop diseases and damage, but the environmental pollution is minimal, and the toxicity to humans and animals is also low, which is beneficial to the sustainable development of the environment.
Furthermore, in the field of materials science, 2-% fluorobenzoic acid also has its place. It can be used in the synthesis of polymer materials with special properties, such as polymers with resistance to corrosion and chemical corrosion. This material can be used in high-end applications such as aerospace and electronics to meet the demanding requirements of high-performance materials.
Therefore, 2-% fluorobenzoic acid has an important position in chemical engineering and related technology exhibitions due to its important uses in the fields of engineering, engineering and materials.
What are the physical properties of 2-chloro-5-hydroxybenzoic acid?
2-% -5-fluorobenzoic acid is one of the most common compounds. Its physical properties are very specific, so let me explain them one by one.
First of all, its outer appearance is often white to beige crystalline powder. This shape is easy to detect and understand, and it is easy to identify in multi-operation.
Furthermore, it is easy to melt. Its melting properties are usually low in a certain range, usually between 170 and 174 ° C. This melting property is important, and it can be used as a reference for the determination of this compound. If melting is normal, it may be implied that the compound contains high or its crystal form is different.
Solubility is also important for physical properties. 2-% -5-fluorobenzoic acid has a certain solubility in normal solution, such as ethanol, acetone, etc. However, in water, its solubility is low. This poor solubility is considered in terms of separation, extraction and inverse solution.
In terms of density, its density is between 1.4 and 1.5 g/cm ³. This density value is due to the physical behavior such as sedimentation and dispersion of this compound in the liquid environment, which has an important impact.
In addition, its solubility is very low, and it is not easy to be released into the empty environment under normal conditions. This characteristic makes it difficult for the compound to be fixed in the normal storage and use, and it is not easy to be lost or polluted in the environment.
Therefore, the physical properties of 2-% -5-fluorobenzoic acid, including externality, solubility, density, and solubility, etc., are of great significance for their applications in chemical synthesis, chemical research, materials science, and other fields.
First of all, its outer appearance is often white to beige crystalline powder. This shape is easy to detect and understand, and it is easy to identify in multi-operation.
Furthermore, it is easy to melt. Its melting properties are usually low in a certain range, usually between 170 and 174 ° C. This melting property is important, and it can be used as a reference for the determination of this compound. If melting is normal, it may be implied that the compound contains high or its crystal form is different.
Solubility is also important for physical properties. 2-% -5-fluorobenzoic acid has a certain solubility in normal solution, such as ethanol, acetone, etc. However, in water, its solubility is low. This poor solubility is considered in terms of separation, extraction and inverse solution.
In terms of density, its density is between 1.4 and 1.5 g/cm ³. This density value is due to the physical behavior such as sedimentation and dispersion of this compound in the liquid environment, which has an important impact.
In addition, its solubility is very low, and it is not easy to be released into the empty environment under normal conditions. This characteristic makes it difficult for the compound to be fixed in the normal storage and use, and it is not easy to be lost or polluted in the environment.
Therefore, the physical properties of 2-% -5-fluorobenzoic acid, including externality, solubility, density, and solubility, etc., are of great significance for their applications in chemical synthesis, chemical research, materials science, and other fields.
What are the chemical properties of 2-chloro-5-hydroxybenzoic acid?
2-% -5-fluorobenzoic acid is a chemical compound, and its chemical properties are very special. In this compound, the presence of the atom affects its overall reaction activity. The atom is active and can be multiplexed. For example, under suitable conditions, the reaction can be generated, and the atomic energy is replaced by other groups, which changes the properties and uses of the compound.
The introduction of fluorine atoms into the 5-fluorobenzoic acid part gives the compound its special properties. Because of its properties, the fluorine atom can change the molecular properties and increase the molecular properties. The change of this property affects the physical properties of the compound, such as melt boiling, solubility, etc. In terms of chemical reaction, fluorine atoms can reduce the density of benzene molecules, which can affect the reactive activity of benzene substitution. Generally speaking, the reactive activity of benzene molecules is reduced, and the reactive property of the reactive domain may also be reduced.
Furthermore, the presence of carboxyl (-COOH) is also important for 2-% -5-fluorobenzoic acid. The carboxyl group is acidic and can be hydrolyzed in aqueous solution to release molecules. This acidity makes it possible to neutralize and react, forming a phase. At the same time, carboxyl groups can also be esterified and reacted, and alcohol can be reacted to form esters under the action of catalysis. This reaction is widely used in the synthesis of esters, and can be used in many products such as fragrances and compounds.
Therefore, the chemical properties of 2-% -5-fluorobenzoic acid are determined by the atoms, fluorine atoms, and carboxyl groups it contains. These groups interact to make it rich in chemical activity, which has important research and application prospects in the fields of chemical synthesis and chemical chemistry.
The introduction of fluorine atoms into the 5-fluorobenzoic acid part gives the compound its special properties. Because of its properties, the fluorine atom can change the molecular properties and increase the molecular properties. The change of this property affects the physical properties of the compound, such as melt boiling, solubility, etc. In terms of chemical reaction, fluorine atoms can reduce the density of benzene molecules, which can affect the reactive activity of benzene substitution. Generally speaking, the reactive activity of benzene molecules is reduced, and the reactive property of the reactive domain may also be reduced.
Furthermore, the presence of carboxyl (-COOH) is also important for 2-% -5-fluorobenzoic acid. The carboxyl group is acidic and can be hydrolyzed in aqueous solution to release molecules. This acidity makes it possible to neutralize and react, forming a phase. At the same time, carboxyl groups can also be esterified and reacted, and alcohol can be reacted to form esters under the action of catalysis. This reaction is widely used in the synthesis of esters, and can be used in many products such as fragrances and compounds.
Therefore, the chemical properties of 2-% -5-fluorobenzoic acid are determined by the atoms, fluorine atoms, and carboxyl groups it contains. These groups interact to make it rich in chemical activity, which has important research and application prospects in the fields of chemical synthesis and chemical chemistry.
What are the synthesis methods of 2-chloro-5-hydroxybenzoic acid?
The synthesis method of 2-% cyanogen-5-fluorobenzoic acid covers a variety of paths. The following is described in detail by Jun.
First, 5-fluorobenzoic acid is used as the starting material, and the carboxyl group is converted into an acyl chloride by co-heating it with halogenated reagents, such as phosphorus oxychloride and phosphorus pentachloride. Subsequently, the acyl chloride and cyanide reagents, such as cuprous cyanide and potassium cyanide, react in a suitable solvent at an appropriate temperature to obtain 2-% cyanogen-5-fluorobenzoic acid. The key to this path is that the halogenation step needs to be strictly controlled at temperature to ensure that the reaction is sufficient and there are no side reactions; the cyanidation step needs to pay attention to the proportion of reagents and the reaction environment to improve the yield.
Second, you can start with 2-methyl-5-fluorobenzoic acid. First, a strong oxidant, such as potassium permanganate, potassium dichromate, etc., oxidizes the methyl group to a carboxyl group. Then, the carboxyl group is treated with a specific dehydrating agent and converted into an acid anhydride. Finally, the acid anhydride reacts with the cyanide agent under suitable conditions to obtain the target product. In this way, the oxidation step should pay attention to the amount of oxidant and the reaction time to prevent excessive oxidation; the dehydration and cyanidation steps also need to precisely control the conditions to ensure the smooth progress of the reaction.
Third, 5-fluorobenzaldehyde is used as the raw material. First, it undergoes an addition reaction with sodium cyanide, sodium bisulfite, etc., to obtain a cy After a series of reactions such as oxidation and hydrolysis, cyanoalcohol is converted into 2-% cyano-5-fluorobenzoic acid. In this method, the addition reaction needs to pay attention to the ratio of reaction medium and reactant; the subsequent oxidative hydrolysis steps need to choose appropriate reagents and conditions to promote the reaction to proceed in the desired direction.
All these synthesis methods have advantages and disadvantages. The purpose of efficient synthesis can be achieved by carefully choosing the optimal path according to the actual situation, such as the availability of raw materials, cost considerations, and the ease of control of reaction conditions.
First, 5-fluorobenzoic acid is used as the starting material, and the carboxyl group is converted into an acyl chloride by co-heating it with halogenated reagents, such as phosphorus oxychloride and phosphorus pentachloride. Subsequently, the acyl chloride and cyanide reagents, such as cuprous cyanide and potassium cyanide, react in a suitable solvent at an appropriate temperature to obtain 2-% cyanogen-5-fluorobenzoic acid. The key to this path is that the halogenation step needs to be strictly controlled at temperature to ensure that the reaction is sufficient and there are no side reactions; the cyanidation step needs to pay attention to the proportion of reagents and the reaction environment to improve the yield.
Second, you can start with 2-methyl-5-fluorobenzoic acid. First, a strong oxidant, such as potassium permanganate, potassium dichromate, etc., oxidizes the methyl group to a carboxyl group. Then, the carboxyl group is treated with a specific dehydrating agent and converted into an acid anhydride. Finally, the acid anhydride reacts with the cyanide agent under suitable conditions to obtain the target product. In this way, the oxidation step should pay attention to the amount of oxidant and the reaction time to prevent excessive oxidation; the dehydration and cyanidation steps also need to precisely control the conditions to ensure the smooth progress of the reaction.
Third, 5-fluorobenzaldehyde is used as the raw material. First, it undergoes an addition reaction with sodium cyanide, sodium bisulfite, etc., to obtain a cy After a series of reactions such as oxidation and hydrolysis, cyanoalcohol is converted into 2-% cyano-5-fluorobenzoic acid. In this method, the addition reaction needs to pay attention to the ratio of reaction medium and reactant; the subsequent oxidative hydrolysis steps need to choose appropriate reagents and conditions to promote the reaction to proceed in the desired direction.
All these synthesis methods have advantages and disadvantages. The purpose of efficient synthesis can be achieved by carefully choosing the optimal path according to the actual situation, such as the availability of raw materials, cost considerations, and the ease of control of reaction conditions.
What is the price range of 2-chloro-5-hydroxybenzoic acid in the market?
Today there is 2-cyanogen-5-fluorobenzoic acid, what is the market price? This is the material used in fine chemicals, and its price often varies due to factors such as quality, supply and demand, and season.
Looking at the chemical market, if the quality is ordinary and the quantity is not huge, the price per gram may be in the tens of dollars. If the quantity is slightly larger, the supplier may have a profit, and the gram price may be reduced to twenty or thirty dollars. However, if high-purity products are required, they are suitable for high-precision fields such as pharmaceutical research and development, and the price is high. High purity of 2-cyanogen-5-fluorobenzoic acid, per gram or more than a hundred dollars, or even higher, because of its difficulty in purification, the cost is also high.
In addition, the state of market supply and demand is also the main reason for the price. If there is a shortage of supply at a time, the price will rise; if there is an oversupply, merchants will sell their goods, and the price may drop. Seasonal climate, etc., sometimes also involves the production of raw materials, which indirectly affects the price of this product.
In order to determine the price of 2-cyanogen-5-fluorobenzoic acid, it is necessary to consult the chemical supplier in detail, compare the quotations of various companies, and at the same time, the quality and quantity required by oneself can be estimated.
Looking at the chemical market, if the quality is ordinary and the quantity is not huge, the price per gram may be in the tens of dollars. If the quantity is slightly larger, the supplier may have a profit, and the gram price may be reduced to twenty or thirty dollars. However, if high-purity products are required, they are suitable for high-precision fields such as pharmaceutical research and development, and the price is high. High purity of 2-cyanogen-5-fluorobenzoic acid, per gram or more than a hundred dollars, or even higher, because of its difficulty in purification, the cost is also high.
In addition, the state of market supply and demand is also the main reason for the price. If there is a shortage of supply at a time, the price will rise; if there is an oversupply, merchants will sell their goods, and the price may drop. Seasonal climate, etc., sometimes also involves the production of raw materials, which indirectly affects the price of this product.
In order to determine the price of 2-cyanogen-5-fluorobenzoic acid, it is necessary to consult the chemical supplier in detail, compare the quotations of various companies, and at the same time, the quality and quantity required by oneself can be estimated.
Scan to WhatsApp
