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2-Chloro-5-Methylnitrobenzene
Linshang Chemical
|
HS Code |
769521 |
| Chemical Formula | C7H6ClNO2 |
| Molar Mass | 171.58 g/mol |
| Appearance | Solid |
| Color | Yellowish |
| Odor | Characteristic |
| Melting Point | 34 - 38 °C |
| Boiling Point | 246 - 248 °C |
| Density | 1.328 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents |
As an accredited 2-Chloro-5-Methylnitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 2 - chloro - 5 - methylnitrobenzene packaged in 1 - kg bottles for chemical use. |
| Storage | 2 - Chloro - 5 - methylnitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions. |
| Shipping | 2 - Chloro - 5 - methylnitrobenzene should be shipped in tightly sealed, corrosion - resistant containers. Label it clearly as a hazardous chemical. Transport under conditions that avoid heat, sparks, and contact with incompatible substances. |
Competitive 2-Chloro-5-Methylnitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 2-Chloro-5-Methylnitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-chloro-5-methylnitrobenzene?
2-Chloro-5-methylnitrobenzene is also an organic compound. Its main uses involve a wide range of chemical fields.
In the preparation of dyes, 2-chloro-5-methylnitrobenzene is the key intermediate. After a series of chemical reactions, dyes with multiple structures can be derived, and these dyes are rich in color and good fastness. They can be widely used in fabric printing and dyeing and other industries to make fabrics get brilliant colors.
In the field of pharmaceutical synthesis, this compound also plays an important role. Due to its specific chemical structure, it can provide key starting materials or intermediates for the synthesis of specific active drug molecules. Through chemical modification and reaction, molecular structures with unique pharmacological activities can be constructed to develop drugs for the treatment of various diseases.
In the manufacture of pesticides, 2-chloro-5-methyl nitrobenzene can be used as an important component in the synthesis of pesticides. After rational chemical transformation, the obtained pesticides have high-efficiency pest control effects, can help agricultural production resist pest attacks, and ensure crop yield and quality.
Furthermore, in the field of materials science, functional materials synthesized from this raw material through specific reactions can have special optoelectronic properties, etc., or can be applied to electronic devices, optical materials, etc., contributing to the development of materials science. In conclusion, 2-chloro-5-methylnitrobenzene plays a key role in many fields of chemical industry due to its unique chemical properties, which is of great significance for promoting the development of related industries.
In the preparation of dyes, 2-chloro-5-methylnitrobenzene is the key intermediate. After a series of chemical reactions, dyes with multiple structures can be derived, and these dyes are rich in color and good fastness. They can be widely used in fabric printing and dyeing and other industries to make fabrics get brilliant colors.
In the field of pharmaceutical synthesis, this compound also plays an important role. Due to its specific chemical structure, it can provide key starting materials or intermediates for the synthesis of specific active drug molecules. Through chemical modification and reaction, molecular structures with unique pharmacological activities can be constructed to develop drugs for the treatment of various diseases.
In the manufacture of pesticides, 2-chloro-5-methyl nitrobenzene can be used as an important component in the synthesis of pesticides. After rational chemical transformation, the obtained pesticides have high-efficiency pest control effects, can help agricultural production resist pest attacks, and ensure crop yield and quality.
Furthermore, in the field of materials science, functional materials synthesized from this raw material through specific reactions can have special optoelectronic properties, etc., or can be applied to electronic devices, optical materials, etc., contributing to the development of materials science. In conclusion, 2-chloro-5-methylnitrobenzene plays a key role in many fields of chemical industry due to its unique chemical properties, which is of great significance for promoting the development of related industries.
What are the physical properties of 2-chloro-5-methylnitrobenzene?
2-Chloro-5-methylnitrobenzene is an organic compound. It has specific physical properties and is described in detail below.
Under normal temperature and pressure, it is mostly a light yellow to brown crystalline solid. The appearance is quite uniform, but the depth of color may vary slightly depending on the purity and preparation method.
As for the melting point, it is about 46-48 ° C. When the ambient temperature reaches this range, the substance gradually melts from a solid state to a liquid state. This melting point characteristic is of critical significance in the process of identification, separation and purification.
In terms of boiling point, it is about 272-274 ° C. At this temperature, 2-chloro-5-methylnitrobenzene will transform from liquid to gaseous state. This boiling point data is an important basis for chemical operations such as distillation.
In terms of density, it is about 1.32 g/cm ³, which is heavier than water. If mixed with water, it will sink to the bottom. This density characteristic cannot be ignored in practical application scenarios such as liquid-liquid separation.
In terms of solubility, 2-chloro-5-methylnitrobenzene is slightly soluble in water. Because water is a polar solvent, and the polar compound is relatively weak, it is difficult to dissolve in water according to the principle of "similar miscibility". However, it is soluble in organic solvents such as ethanol, ether, benzene, etc. In these solvents, the compound can be well dispersed and dissolved. This solubility facilitates the operation of organic synthesis and related chemical reactions. Many reactions need to be carried out smoothly in an environment suitable for organic solvents.
In addition, 2-chloro-5-methylnitrobenzene is volatile and can evaporate slowly in the air. Although its volatility is not strong, it is still necessary to pay attention when storing and using it to prevent it from escaping into the environment and causing potential harm.
Under normal temperature and pressure, it is mostly a light yellow to brown crystalline solid. The appearance is quite uniform, but the depth of color may vary slightly depending on the purity and preparation method.
As for the melting point, it is about 46-48 ° C. When the ambient temperature reaches this range, the substance gradually melts from a solid state to a liquid state. This melting point characteristic is of critical significance in the process of identification, separation and purification.
In terms of boiling point, it is about 272-274 ° C. At this temperature, 2-chloro-5-methylnitrobenzene will transform from liquid to gaseous state. This boiling point data is an important basis for chemical operations such as distillation.
In terms of density, it is about 1.32 g/cm ³, which is heavier than water. If mixed with water, it will sink to the bottom. This density characteristic cannot be ignored in practical application scenarios such as liquid-liquid separation.
In terms of solubility, 2-chloro-5-methylnitrobenzene is slightly soluble in water. Because water is a polar solvent, and the polar compound is relatively weak, it is difficult to dissolve in water according to the principle of "similar miscibility". However, it is soluble in organic solvents such as ethanol, ether, benzene, etc. In these solvents, the compound can be well dispersed and dissolved. This solubility facilitates the operation of organic synthesis and related chemical reactions. Many reactions need to be carried out smoothly in an environment suitable for organic solvents.
In addition, 2-chloro-5-methylnitrobenzene is volatile and can evaporate slowly in the air. Although its volatility is not strong, it is still necessary to pay attention when storing and using it to prevent it from escaping into the environment and causing potential harm.
What is the chemistry of 2-chloro-5-methylnitrobenzene?
2-Chloro-5-methylnitrobenzene, this is an organic compound with specific chemical properties. In its structure, chlorine atoms, methyl groups and nitro groups are attached to the benzene ring. This structure makes its chemical properties unique, which is related to the reactivity and stability.
In terms of reactivity, the electron cloud density of the benzene ring decreases due to the electron-absorbing effect of the nitro group, and the activity of the electrophilic substitution reaction decreases. However, although the chlorine atom is an ortho-para-site group, the nitro group strongly absorbs electrons, so that the electrophilic substitution reaction is less likely to occur in the ortho-site of the chlorine atom and more likely to occur in the meta-site (although the overall activity is lower than that of benzene). For example, when the electrophilic substitution such as hal
In terms of stability, due to the electron absorption of nitro and chlorine atoms, the distribution of molecular electron clouds changes and the energy state is different. The presence of nitro groups increases the polarity of molecules, which affects their physical properties, such as boiling point, melting point, etc. The electron-giving effect of methyl groups affects the benzene ring electron cloud to a certain extent, but the effect is weaker than that of nitro and chlorine atoms.
In some organic synthesis, 2-chloro-5-methyl nitrobenzene can be used as an intermediate. Due to its different substituents, chlorine atoms can be replaced by other nucleophiles through specific reactions, such as nucleophilic substitution reactions, thereby introducing new functional groups, realizing molecular structure transformation, and synthesizing more complex organic compounds. However, the reaction conditions need to be precisely regulated according to factors such as nucleophilic reagent activity and substrate characteristics.
In terms of reactivity, the electron cloud density of the benzene ring decreases due to the electron-absorbing effect of the nitro group, and the activity of the electrophilic substitution reaction decreases. However, although the chlorine atom is an ortho-para-site group, the nitro group strongly absorbs electrons, so that the electrophilic substitution reaction is less likely to occur in the ortho-site of the chlorine atom and more likely to occur in the meta-site (although the overall activity is lower than that of benzene). For example, when the electrophilic substitution such as hal
In terms of stability, due to the electron absorption of nitro and chlorine atoms, the distribution of molecular electron clouds changes and the energy state is different. The presence of nitro groups increases the polarity of molecules, which affects their physical properties, such as boiling point, melting point, etc. The electron-giving effect of methyl groups affects the benzene ring electron cloud to a certain extent, but the effect is weaker than that of nitro and chlorine atoms.
In some organic synthesis, 2-chloro-5-methyl nitrobenzene can be used as an intermediate. Due to its different substituents, chlorine atoms can be replaced by other nucleophiles through specific reactions, such as nucleophilic substitution reactions, thereby introducing new functional groups, realizing molecular structure transformation, and synthesizing more complex organic compounds. However, the reaction conditions need to be precisely regulated according to factors such as nucleophilic reagent activity and substrate characteristics.
What are 2-chloro-5-methylnitrobenzene synthesis methods?
To make 2-chloro-5-methylnitrobenzene, there are many ways to synthesize it. Common ones can be obtained by nitration of p-methylchlorobenzene. In this process, p-methylchlorobenzene interacts with nitrifying reagents such as concentrated nitric acid and concentrated sulfuric acid under appropriate reaction conditions. In the mixed acid, concentrated sulfuric acid acts as a catalyst to cause nitric acid to produce nitroyl cation (NO ²), which is electrophilic and attacks the benzene ring of p-methylchlorobenzene. Because methyl is an ortho-para-site group, chlorine is also an ortho-site group, and the positioning effect of methyl is stronger than that of chlorine, the nitro group mainly enters the para-site of methyl to generate 2-chloro-5-methylnitrobenzene.
Or you can use toluene as the starting material and nitrate to obtain p-nitrotoluene. At this time, the benzene ring of toluene is mixed with acid, and the nitro group mainly enters the para-methyl group. Then, p-nitrotoluene is chlorinated again. Under appropriate catalyst and reaction conditions, the hydrogen atom of the nitro ortho-position on the benzene ring is replaced by a chlorine atom, and 2-chloro-5-methylnitrobenzene can also be obtained.
Furthermore, with m-methylaniline as the starting material, it is first reacted by diazotization to obtain a diazonium salt. After reacting with cuprous chloride and hydrochloric acid, a Sandmeier reaction occurs, and the diazonium group is replaced by a chlorine atom to obtain m-chlorotoluene The target product 2-chloro-5-methylnitrobenzene can also be prepared by nitration of m-chlorotoluene, and the nitro group enters the para-methyl position.
Or you can use toluene as the starting material and nitrate to obtain p-nitrotoluene. At this time, the benzene ring of toluene is mixed with acid, and the nitro group mainly enters the para-methyl group. Then, p-nitrotoluene is chlorinated again. Under appropriate catalyst and reaction conditions, the hydrogen atom of the nitro ortho-position on the benzene ring is replaced by a chlorine atom, and 2-chloro-5-methylnitrobenzene can also be obtained.
Furthermore, with m-methylaniline as the starting material, it is first reacted by diazotization to obtain a diazonium salt. After reacting with cuprous chloride and hydrochloric acid, a Sandmeier reaction occurs, and the diazonium group is replaced by a chlorine atom to obtain m-chlorotoluene The target product 2-chloro-5-methylnitrobenzene can also be prepared by nitration of m-chlorotoluene, and the nitro group enters the para-methyl position.
2-chloro-5-methylnitrobenzene What are the precautions during storage and transportation?
2-Chloro-5-methylnitrobenzene is one of the organic compounds. When storing and transporting, pay attention to many matters.
First storage. This substance should be placed in a cool and well-ventilated place. Because it is easy to cause danger when heated, it is important to stay away from fire and heat sources. If heated, it may cause its chemical properties to change, and even the risk of explosion. And it needs to be stored separately from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed. Because it is easy to react chemically with various substances, once mixed, or react violently, endangering safety. Where it is stored, suitable materials should be prepared to contain leaks to prevent accidents.
Second discussion on transportation. When transporting, make sure that the container does not leak, collapse, fall or damage. Because of its certain toxicity and danger, if the container is damaged and leaks, it will pollute the environment and endanger people and animals. Transportation vehicles should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. During driving, it is necessary to prevent exposure to the sun, rain and high temperature. Summer transportation should be carried out in the morning and evening to avoid high temperature periods. Transportation should be carried out according to the specified route, and do not stop in residential areas and densely populated areas.
In short, during the storage and transportation of 2-chloro-5-methylnitrobenzene, all details are related to safety, and must be treated with caution and acted in strict accordance with regulations to ensure safety.
First storage. This substance should be placed in a cool and well-ventilated place. Because it is easy to cause danger when heated, it is important to stay away from fire and heat sources. If heated, it may cause its chemical properties to change, and even the risk of explosion. And it needs to be stored separately from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed. Because it is easy to react chemically with various substances, once mixed, or react violently, endangering safety. Where it is stored, suitable materials should be prepared to contain leaks to prevent accidents.
Second discussion on transportation. When transporting, make sure that the container does not leak, collapse, fall or damage. Because of its certain toxicity and danger, if the container is damaged and leaks, it will pollute the environment and endanger people and animals. Transportation vehicles should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. During driving, it is necessary to prevent exposure to the sun, rain and high temperature. Summer transportation should be carried out in the morning and evening to avoid high temperature periods. Transportation should be carried out according to the specified route, and do not stop in residential areas and densely populated areas.
In short, during the storage and transportation of 2-chloro-5-methylnitrobenzene, all details are related to safety, and must be treated with caution and acted in strict accordance with regulations to ensure safety.
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