Linshang Chemical
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2-Chloro-5-Nitrobenzenesulfonic Acid
Linshang Chemical
|
HS Code |
668028 |
| Chemical Formula | C6H3ClNO5S |
| Molar Mass | 253.61 g/mol |
| Appearance | Solid |
| Physical State At Room Temperature | Solid |
| Solubility In Water | Soluble |
| Melting Point | Around 130 - 135 °C |
| Boiling Point | Decomposes before boiling |
| Acidity | Acidic due to sulfonic acid group |
| Color | Yellowish - brown |
| Odor | Characteristic, pungent |
As an accredited 2-Chloro-5-Nitrobenzenesulfonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 2 - chloro - 5 - nitrobenzenesulfonic Acid packaged in a sealed plastic bottle. |
| Storage | 2 - Chloro - 5 - nitrobenzenesulfonic acid should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent moisture absorption and exposure to air. Store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to avoid chemical reactions. |
| Shipping | 2 - chloro - 5 - nitrobenzenesulfonic acid is shipped in accordance with strict hazardous chemicals regulations. It's packed in specialized containers to prevent leakage, transported via approved carriers, with proper labeling and safety documentation. |
Competitive 2-Chloro-5-Nitrobenzenesulfonic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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What are the chemical properties of 2-chloro-5-nitrobenzenesulfonic Acid?
2-Chloro-5-nitrobenzenesulfonic acid, an organic compound with unique chemical properties. It is acidic and can be partially ionized in water to release hydrogen ions, so its aqueous solution is acidic.
In terms of reactivity, due to the presence of chlorine atoms, nitro groups and sulfonic acid groups in the molecule, the reactivity is quite high. Chlorine atoms can undergo nucleophilic substitution reactions. When encountering nucleophilic reagents, nucleophilic reagents will attack the carbon atoms connected to chlorine, and the chlorine atoms will leave in the form of chloride ions to form new organic compounds.
The nitro group is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring, but can enhance the activity of the adjacent and para-carbon atoms, which is conducive to the specific nucleophilic substitution reaction. At the same time, the nitro group can be reduced under certain conditions, for example, under the action of a suitable reducing agent, it can be gradually reduced to groups such as amino groups.
The sulfonic acid group is a strong hydrophilic group, which endows the compound with good water solubility. In addition, the basic body of sulfonic acid is relatively stable, and it is not easy to react under normal conditions, but under severe conditions such as high temperature and strong acid, the sulfonic acid group may undergo reactions
2-chloro-5-nitrobenzenesulfonic acid is often used as an important intermediate in the field of organic synthesis due to its special combination of functional groups, used to prepare a variety of organic compounds with special structures and functions.
In terms of reactivity, due to the presence of chlorine atoms, nitro groups and sulfonic acid groups in the molecule, the reactivity is quite high. Chlorine atoms can undergo nucleophilic substitution reactions. When encountering nucleophilic reagents, nucleophilic reagents will attack the carbon atoms connected to chlorine, and the chlorine atoms will leave in the form of chloride ions to form new organic compounds.
The nitro group is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring, but can enhance the activity of the adjacent and para-carbon atoms, which is conducive to the specific nucleophilic substitution reaction. At the same time, the nitro group can be reduced under certain conditions, for example, under the action of a suitable reducing agent, it can be gradually reduced to groups such as amino groups.
The sulfonic acid group is a strong hydrophilic group, which endows the compound with good water solubility. In addition, the basic body of sulfonic acid is relatively stable, and it is not easy to react under normal conditions, but under severe conditions such as high temperature and strong acid, the sulfonic acid group may undergo reactions
2-chloro-5-nitrobenzenesulfonic acid is often used as an important intermediate in the field of organic synthesis due to its special combination of functional groups, used to prepare a variety of organic compounds with special structures and functions.
What are the main uses of 2-chloro-5-nitrobenzenesulfonic Acid?
2-Chloro-5-nitrobenzenesulfonic acid, which is one of the organic compounds. Its uses are quite extensive and are described as follows:
First, it is a key intermediate in the field of dye synthesis. Through specific chemical reactions, it can be converted into many colorful dyes. Due to the chlorine atoms, nitro groups and sulfonic acid groups attached to the benzene ring, it is endowed with unique chemical activity and can be cleverly combined with other compounds to construct dye molecules with different colors and properties. Dyes are indispensable in textile, printing and dyeing industries. After the fabric is dyed, it is colorful and beautiful.
Second, it also plays an important role in the field of pharmaceutical chemistry. With its special chemical structure, it can be used as a starting material to synthesize certain drug molecules with specific pharmacological activities after a series of complex reaction steps. For example, its structural properties help to design and construct compounds that interact with specific targets in organisms, providing an important cornerstone for the development of new drugs.
Third, it plays a non-negligible role in the preparation of pesticides. It can be used as a raw material for the synthesis of pesticide active ingredients. The groups in its structure can give pesticides specific biological activities, such as insecticidal, bactericidal, herbicide, etc. By reacting with other chemicals, the resulting pesticide products can effectively protect crops from pests and diseases, and improve crop yield and quality.
Fourth, in the field of organic synthesis chemistry, 2-chloro-5-nitrobenzenesulfonic acid is often used as an important reagent in organic synthesis due to its unique combination of functional groups. It can participate in various types of organic reactions, such as nucleophilic substitution reactions, electrophilic substitution reactions, etc., providing the possibility for constructing more complex organic molecular structures and assisting organic chemists to expand the types and applications of organic compounds.
First, it is a key intermediate in the field of dye synthesis. Through specific chemical reactions, it can be converted into many colorful dyes. Due to the chlorine atoms, nitro groups and sulfonic acid groups attached to the benzene ring, it is endowed with unique chemical activity and can be cleverly combined with other compounds to construct dye molecules with different colors and properties. Dyes are indispensable in textile, printing and dyeing industries. After the fabric is dyed, it is colorful and beautiful.
Second, it also plays an important role in the field of pharmaceutical chemistry. With its special chemical structure, it can be used as a starting material to synthesize certain drug molecules with specific pharmacological activities after a series of complex reaction steps. For example, its structural properties help to design and construct compounds that interact with specific targets in organisms, providing an important cornerstone for the development of new drugs.
Third, it plays a non-negligible role in the preparation of pesticides. It can be used as a raw material for the synthesis of pesticide active ingredients. The groups in its structure can give pesticides specific biological activities, such as insecticidal, bactericidal, herbicide, etc. By reacting with other chemicals, the resulting pesticide products can effectively protect crops from pests and diseases, and improve crop yield and quality.
Fourth, in the field of organic synthesis chemistry, 2-chloro-5-nitrobenzenesulfonic acid is often used as an important reagent in organic synthesis due to its unique combination of functional groups. It can participate in various types of organic reactions, such as nucleophilic substitution reactions, electrophilic substitution reactions, etc., providing the possibility for constructing more complex organic molecular structures and assisting organic chemists to expand the types and applications of organic compounds.
What is the synthesis method of 2-chloro-5-nitrobenzenesulfonic Acid?
The synthesis method of 2-chloro-5-nitrobenzenesulfonic acid, although the ancient book "Tiangong Kaiwu" does not contain this specific method in detail, it can be deduced according to the principles of chemistry.
To synthesize this compound, benzenesulfonic acid is often used as the starting material. First, benzenesulfonic acid is nitrified in a mixed acid system of nitric acid and sulfuric acid under appropriate reaction conditions. Nitric acid is catalyzed by sulfuric acid to generate nitroyl positive ions (NO ²). This positive ion has strong electrophilicity and can attack the higher electron cloud density on the benzene ring of benzenesulfonic acid. The sulfonic acid group of benzenesulfonic acid is the meta-site group, which makes the electron cloud density of the benzene ring meta-site relatively high, so the nitro group easily replaces the hydrogen atom of the benzene ring meta-site to form 3-nitrobenzenesulfonic acid.
Then, the 3-nitrobenzenesulfonic acid is chlorinated. Suitable chlorination reagents can be used, such as phosphorus trichloride (PCl), phosphorus pentachloride (PCl) or chlorine (Cl). If chlorine is used as a chlorination agent, under the condition of light or the presence of a catalyst, the chlorine gas molecules will uniformly crack and produce chlorine free radicals ( Chlorine radicals attack the 3-nitrobenzenesulfonic acid benzene ring. Due to the co-localization effect of the nitro group and the sulfonic acid group, the chlorine atom mainly replaces the hydrogen atom on the benzene ring that is in the ortho position with the nitro group and in the meso position with the sulfonic acid group, that is, 2-chloro-5-nitrobenzenesulfonic acid is formed.
During the reaction process, attention should be paid to the conditions of each step of the reaction. During the nitrification reaction, the concentration of mixed acid, the reaction temperature and time all affect the yield and purity of the product. If the temperature is too high, it is easy to cause side reactions such as polynitrification; if the temperature is too low, the reaction rate will be slow. The same is true for It is necessary to fine-tune each parameter to obtain 2-chloro-5-nitrobenzenesulfonic acid with higher yield and purity.
To synthesize this compound, benzenesulfonic acid is often used as the starting material. First, benzenesulfonic acid is nitrified in a mixed acid system of nitric acid and sulfuric acid under appropriate reaction conditions. Nitric acid is catalyzed by sulfuric acid to generate nitroyl positive ions (NO ²). This positive ion has strong electrophilicity and can attack the higher electron cloud density on the benzene ring of benzenesulfonic acid. The sulfonic acid group of benzenesulfonic acid is the meta-site group, which makes the electron cloud density of the benzene ring meta-site relatively high, so the nitro group easily replaces the hydrogen atom of the benzene ring meta-site to form 3-nitrobenzenesulfonic acid.
Then, the 3-nitrobenzenesulfonic acid is chlorinated. Suitable chlorination reagents can be used, such as phosphorus trichloride (PCl), phosphorus pentachloride (PCl) or chlorine (Cl). If chlorine is used as a chlorination agent, under the condition of light or the presence of a catalyst, the chlorine gas molecules will uniformly crack and produce chlorine free radicals ( Chlorine radicals attack the 3-nitrobenzenesulfonic acid benzene ring. Due to the co-localization effect of the nitro group and the sulfonic acid group, the chlorine atom mainly replaces the hydrogen atom on the benzene ring that is in the ortho position with the nitro group and in the meso position with the sulfonic acid group, that is, 2-chloro-5-nitrobenzenesulfonic acid is formed.
During the reaction process, attention should be paid to the conditions of each step of the reaction. During the nitrification reaction, the concentration of mixed acid, the reaction temperature and time all affect the yield and purity of the product. If the temperature is too high, it is easy to cause side reactions such as polynitrification; if the temperature is too low, the reaction rate will be slow. The same is true for It is necessary to fine-tune each parameter to obtain 2-chloro-5-nitrobenzenesulfonic acid with higher yield and purity.
What are the precautions for 2-chloro-5-nitrobenzenesulfonic Acid in storage and transportation?
2-Chloro-5-nitrobenzenesulfonic acid is a common chemical in the chemical industry. When storing and transporting, many important items need to be careful to prevent accidents and ensure the safety of personnel and the environment.
In terms of its storage, the first environmental choice. It must be placed in a cool, dry and well-ventilated place. This is because of its active chemical properties, high temperature and humid environment is prone to deterioration or chemical reactions. If the temperature is too high, it may accelerate its decomposition; if the humidity is too high, it may absorb moisture, affect the quality, and even induce dangerous reactions.
Furthermore, it needs to be properly isolated from other substances. 2-Chloro-5-nitrobenzenesulfonic acid is corrosive and oxidizing, and cannot be co-stored with flammable, explosive, reducing substances and alkalis. If it is mixed with flammable substances, once an accident occurs, it may cause violent combustion or even explosion; contact with alkalis will cause neutralization reaction, or cause sudden heat release, which is a safety hazard.
Storage containers are also crucial. Corrosive-resistant materials should be selected, such as special plastic or glass containers. Due to metal containers or reactions with the chemical, the container will be damaged and the material will leak. At the same time, the container must be well sealed to prevent leakage and volatilization, polluting the environment and endangering human health.
As for the transportation process, the packaging must be strong. Ensure that the packaging is not damaged and the materials are not leaked during handling, loading and unloading and transportation. Special chemical transport vehicles should be selected, and the necessary emergency equipment and protective equipment should be equipped in the vehicle to prepare for emergencies.
Transportation personnel also need to undergo professional training, familiar with the characteristics, hazards and emergency treatment methods of 2-chloro-5-nitrobenzenesulfonic acid. Transportation route planning should avoid sensitive areas such as densely populated areas and water source reserves to reduce the impact of accidents.
To sum up, the storage and transportation of 2-chloro-5-nitrobenzenesulfonic acid should not be ignored in terms of environment, isolation, containers, packaging, personnel, etc., and operate strictly according to specifications to ensure safety.
In terms of its storage, the first environmental choice. It must be placed in a cool, dry and well-ventilated place. This is because of its active chemical properties, high temperature and humid environment is prone to deterioration or chemical reactions. If the temperature is too high, it may accelerate its decomposition; if the humidity is too high, it may absorb moisture, affect the quality, and even induce dangerous reactions.
Furthermore, it needs to be properly isolated from other substances. 2-Chloro-5-nitrobenzenesulfonic acid is corrosive and oxidizing, and cannot be co-stored with flammable, explosive, reducing substances and alkalis. If it is mixed with flammable substances, once an accident occurs, it may cause violent combustion or even explosion; contact with alkalis will cause neutralization reaction, or cause sudden heat release, which is a safety hazard.
Storage containers are also crucial. Corrosive-resistant materials should be selected, such as special plastic or glass containers. Due to metal containers or reactions with the chemical, the container will be damaged and the material will leak. At the same time, the container must be well sealed to prevent leakage and volatilization, polluting the environment and endangering human health.
As for the transportation process, the packaging must be strong. Ensure that the packaging is not damaged and the materials are not leaked during handling, loading and unloading and transportation. Special chemical transport vehicles should be selected, and the necessary emergency equipment and protective equipment should be equipped in the vehicle to prepare for emergencies.
Transportation personnel also need to undergo professional training, familiar with the characteristics, hazards and emergency treatment methods of 2-chloro-5-nitrobenzenesulfonic acid. Transportation route planning should avoid sensitive areas such as densely populated areas and water source reserves to reduce the impact of accidents.
To sum up, the storage and transportation of 2-chloro-5-nitrobenzenesulfonic acid should not be ignored in terms of environment, isolation, containers, packaging, personnel, etc., and operate strictly according to specifications to ensure safety.
2-chloro-5-nitrobenzenesulfonic impact of Acid on the environment
2-Chloro-5-nitrobenzenesulfonic acid, the impact of this substance on the environment is particularly important and cannot be ignored.
Its properties are harmful. In terms of aquatic ecosystems, if it accidentally flows into rivers, lakes and seas and other water bodies, this substance may be toxic to aquatic organisms. Due to its special chemical structure, it contains chlorine, nitro and sulfonic acid groups and other functional groups, which may interfere with the physiological metabolism of aquatic organisms. Aquatic plants ingest water containing this substance, and their key physiological processes such as photosynthesis may be blocked, resulting in stunted growth and even withering and death. Aquatic animals such as fish, shellfish, etc., after exposure to this substance, their nervous system and respiratory system may be damaged, resulting in abnormal movement and respiratory disorders. Under long-term exposure, the population may also decrease sharply.
In the soil environment, if this substance penetrates into the soil, it may change the chemical properties of the soil. Its acidic properties, or cause soil acidification, affect the community structure and function of microorganisms in the soil. Soil microorganisms are essential for the maintenance of soil fertility and the decomposition and transformation of organic matter. Their activity and species are suppressed, and soil fertility decreases, affecting the absorption of nutrients by plant roots, resulting in a decline in crop yield and quality.
In the atmospheric environment, although this substance has limited volatilization at room temperature, if the production, transportation and other processes are not handled properly, its tiny particles or volatiles will enter the atmosphere, diffuse through atmospheric circulation, or participate in complex atmospheric chemical reactions, affecting air quality, causing irritation and damage to human and other biological respiratory systems.
Furthermore, this substance degrades slowly in the environment, easily accumulates in environmental media, and is transmitted and enriched through the food chain, eventually endangering human health at the top of the food chain. Therefore, such substances should be handled with caution to prevent them from causing serious harm to the environment.
Its properties are harmful. In terms of aquatic ecosystems, if it accidentally flows into rivers, lakes and seas and other water bodies, this substance may be toxic to aquatic organisms. Due to its special chemical structure, it contains chlorine, nitro and sulfonic acid groups and other functional groups, which may interfere with the physiological metabolism of aquatic organisms. Aquatic plants ingest water containing this substance, and their key physiological processes such as photosynthesis may be blocked, resulting in stunted growth and even withering and death. Aquatic animals such as fish, shellfish, etc., after exposure to this substance, their nervous system and respiratory system may be damaged, resulting in abnormal movement and respiratory disorders. Under long-term exposure, the population may also decrease sharply.
In the soil environment, if this substance penetrates into the soil, it may change the chemical properties of the soil. Its acidic properties, or cause soil acidification, affect the community structure and function of microorganisms in the soil. Soil microorganisms are essential for the maintenance of soil fertility and the decomposition and transformation of organic matter. Their activity and species are suppressed, and soil fertility decreases, affecting the absorption of nutrients by plant roots, resulting in a decline in crop yield and quality.
In the atmospheric environment, although this substance has limited volatilization at room temperature, if the production, transportation and other processes are not handled properly, its tiny particles or volatiles will enter the atmosphere, diffuse through atmospheric circulation, or participate in complex atmospheric chemical reactions, affecting air quality, causing irritation and damage to human and other biological respiratory systems.
Furthermore, this substance degrades slowly in the environment, easily accumulates in environmental media, and is transmitted and enriched through the food chain, eventually endangering human health at the top of the food chain. Therefore, such substances should be handled with caution to prevent them from causing serious harm to the environment.
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