Linshang Chemical
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2-Chloro-Benzeneethanamine
Linshang Chemical
|
HS Code |
939469 |
| Chemical Formula | C8H10ClN |
| Molar Mass | 155.625 g/mol |
| Appearance | Colorless to light yellow liquid |
| Odor | Characteristic amine - like odor |
| Density | Approx. 1.13 g/cm³ |
| Boiling Point | 235 - 237 °C |
| Solubility In Water | Slightly soluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Flash Point | 101 °C |
| Pka | Approx. 9.3 (amine group) |
| Vapor Pressure | Low at room temperature |
As an accredited 2-Chloro-Benzeneethanamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 g of 2 - chloro - benzeneethanamine packaged in a sealed, corrosion - resistant bottle. |
| Storage | 2 - chloro - benzeneethanamine should be stored in a cool, dry, well - ventilated area away from heat, flames, and ignition sources. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, acids, and bases to prevent chemical reactions. Label the storage container clearly with its name and safety warnings. |
| Shipping | 2 - chloro - benzeneethanamine is a chemical that may require special handling. Shipping should follow strict regulations, using appropriate containers to prevent leakage, and be accompanied by safety data sheets for proper hazard communication. |
Competitive 2-Chloro-Benzeneethanamine prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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What are the physical properties of 2-chloro-benzeneethanamine?
2-Chloro-phenethylamine, this is an organic compound with specific physical properties. In terms of its color state, it is mostly a colorless to light yellow liquid at room temperature, like the initial melting of amber, slightly yellowish in the clear, and it has a smart state. In terms of smell, it emits a pungent and amine-like smell, which is like a sharp arrow, directly penetrating the olfactory defense line, which is impressive.
When talking about the boiling point, about a specific temperature range, when heated to the corresponding degree, the molecules can break free and gradually change from a liquid state to a gaseous state, just like a bird breaking free from a cage. Its melting point is in a certain range, and when it cools down to this point, the molecules are arranged in an orderly manner, and gradually solidify from a flowing state, like a frozen river, losing their agility.
Solubility is also an important property. In common organic solvents such as ethanol and ether, it can dissolve well, just like salt entering water, and the phase is seamless. Due to the principle of similar phase dissolution, its structure is compatible with organic solvents. In water, the solubility is relatively limited, just like oil floating in water, only a small amount of mixing can occur.
In terms of density, compared with water, it shows a specific value, either slightly larger than water or slightly smaller than water. This property is of great significance in separation, mixing and other operations. It can be separated from other substances by specific methods, such as extraction and liquid separation.
In addition, the vapor pressure of 2-chloro-phenethylamine also has corresponding values under specific conditions, reflecting the degree of volatilization. If the vapor pressure is high, it is easy to volatilize. It is like light smoke and gradually disperses in the air; if the vapor pressure is low, it is relatively stable, such as a rock, and it is not easy to dissipate. These many physical properties are crucial in the fields of organic synthesis, drug research and development, and lay the foundation for related operations and research.
When talking about the boiling point, about a specific temperature range, when heated to the corresponding degree, the molecules can break free and gradually change from a liquid state to a gaseous state, just like a bird breaking free from a cage. Its melting point is in a certain range, and when it cools down to this point, the molecules are arranged in an orderly manner, and gradually solidify from a flowing state, like a frozen river, losing their agility.
Solubility is also an important property. In common organic solvents such as ethanol and ether, it can dissolve well, just like salt entering water, and the phase is seamless. Due to the principle of similar phase dissolution, its structure is compatible with organic solvents. In water, the solubility is relatively limited, just like oil floating in water, only a small amount of mixing can occur.
In terms of density, compared with water, it shows a specific value, either slightly larger than water or slightly smaller than water. This property is of great significance in separation, mixing and other operations. It can be separated from other substances by specific methods, such as extraction and liquid separation.
In addition, the vapor pressure of 2-chloro-phenethylamine also has corresponding values under specific conditions, reflecting the degree of volatilization. If the vapor pressure is high, it is easy to volatilize. It is like light smoke and gradually disperses in the air; if the vapor pressure is low, it is relatively stable, such as a rock, and it is not easy to dissipate. These many physical properties are crucial in the fields of organic synthesis, drug research and development, and lay the foundation for related operations and research.
What are the chemical properties of 2-chloro-benzeneethanamine?
2-Chloro-phenethylamine, its chemical properties are quite important and characteristic. In this substance, the chlorine atom is structurally connected to phenethylamine, giving it unique properties.
In terms of reactivity, the chlorine atom has electron-absorbing properties, which can reduce the electron cloud density of the benzene ring. In this way, in the electrophilic substitution reaction, its reactivity changes compared with phenethylamine, and the specific position on the benzene ring reacts differently to the electrophilic reagent. For example, when the electrophilic reagent attacks the benzene ring, it is affected by the chlorine atom, and the reaction check point may be more inclined to the meta-position.
Furthermore, the amino group (\ (- NH_ {2}\)) is an important functional group of the molecule and has It can react with acids to form corresponding salts. In the case of hydrochloric acid, 2-chloro-phenethylamine hydrochloride can be formed. This reaction is often used in organic synthesis and drug preparation to improve the stability or solubility of compounds.
At the same time, the chlorine atom of 2-chloro-phenethylamine can participate in the nucleophilic substitution reaction. In the case of suitable nucleophilic reagents, such as sodium alcohol or amines, chlorine atoms can be replaced to form new carbon-heteroatom bonds, providing a way for the synthesis of more complex organic compounds.
In terms of redox properties, amino groups can be oxidized under specific conditions to form corresponding nitrogen-containing oxides. Although the benzene ring is relatively stable, under the action of strong oxidants, oxidation reactions may also occur, resulting in changes in the structure of the benzene ring.
In summary, 2-chloro-phenethylamine exhibits various chemical properties due to the existence of chlorine atoms and amino groups, and has important research and application value in organic synthesis, medicinal chemistry and other fields.
In terms of reactivity, the chlorine atom has electron-absorbing properties, which can reduce the electron cloud density of the benzene ring. In this way, in the electrophilic substitution reaction, its reactivity changes compared with phenethylamine, and the specific position on the benzene ring reacts differently to the electrophilic reagent. For example, when the electrophilic reagent attacks the benzene ring, it is affected by the chlorine atom, and the reaction check point may be more inclined to the meta-position.
Furthermore, the amino group (\ (- NH_ {2}\)) is an important functional group of the molecule and has It can react with acids to form corresponding salts. In the case of hydrochloric acid, 2-chloro-phenethylamine hydrochloride can be formed. This reaction is often used in organic synthesis and drug preparation to improve the stability or solubility of compounds.
At the same time, the chlorine atom of 2-chloro-phenethylamine can participate in the nucleophilic substitution reaction. In the case of suitable nucleophilic reagents, such as sodium alcohol or amines, chlorine atoms can be replaced to form new carbon-heteroatom bonds, providing a way for the synthesis of more complex organic compounds.
In terms of redox properties, amino groups can be oxidized under specific conditions to form corresponding nitrogen-containing oxides. Although the benzene ring is relatively stable, under the action of strong oxidants, oxidation reactions may also occur, resulting in changes in the structure of the benzene ring.
In summary, 2-chloro-phenethylamine exhibits various chemical properties due to the existence of chlorine atoms and amino groups, and has important research and application value in organic synthesis, medicinal chemistry and other fields.
What are the main uses of 2-chloro-benzeneethanamine?
2-Chloro-benzeneethanamine, or 2-chlorophenethylamine, has a wide range of uses. In the field of medicine, it is a key intermediate in organic synthesis and can be used to create many drugs. For example, in the preparation of some antidepressant drugs, 2-chlorophenethanamine plays an indispensable role. Through specific chemical reactions, it is cleverly combined with other compounds to build a complex molecular structure that regulates the function of neurotransmitters, thereby achieving the purpose of relieving depression symptoms.
It also has applications in materials science. The synthesis of some functional polymer materials involves its participation. Due to its special chemical structure, it can endow polymer materials with unique properties, such as improving the solubility of materials and enhancing the compatibility of materials with other substances, thereby broadening the application scope of polymer materials in different fields, such as coatings, adhesives and other industries.
In the field of organic synthetic chemistry, 2-chlorophenethylamine is more frequently used. Organic chemists can use various chemical reactions to transform and modify them based on their structural characteristics to prepare organic compounds with diverse structures and functions, providing a rich material basis and research materials for the development of organic synthetic chemistry, and promoting the creation and application of new organic compounds.
It also has applications in materials science. The synthesis of some functional polymer materials involves its participation. Due to its special chemical structure, it can endow polymer materials with unique properties, such as improving the solubility of materials and enhancing the compatibility of materials with other substances, thereby broadening the application scope of polymer materials in different fields, such as coatings, adhesives and other industries.
In the field of organic synthetic chemistry, 2-chlorophenethylamine is more frequently used. Organic chemists can use various chemical reactions to transform and modify them based on their structural characteristics to prepare organic compounds with diverse structures and functions, providing a rich material basis and research materials for the development of organic synthetic chemistry, and promoting the creation and application of new organic compounds.
What are 2-chloro-benzeneethanamine synthesis methods?
The synthesis method of Fu 2-chloro-phenethylamine often involves several paths. One method starts with styrene, first adds with hydrogen chloride to obtain 1-chloro-2-phenylethane, reacts with ammonia, and undergoes nucleophilic substitution to obtain 2-chloro-phenethylamine. Among them, when hydrogen chloride is added to styrene, a suitable temperature and a catalyst are required to make the reaction preferentially form to the desired product.
Another method uses o-chlorobenzaldehyde as the starting material. After reducing amination, it interacts with ammonia and reducing agents. For example, sodium borohydride or sodium cyanoborohydride is used as reducing agent. In an appropriate solvent, such as an alcohol solvent, 2-chloro-phenethylamine can be obtained. This process requires temperature control and reaction time to ensure complete reaction and reduce side reactions.
Furthermore, it is also possible to use o-chlorobenzyl chloride as a raw material. It first undergoes nucleophilic substitution with sodium cyanide, introduces cyanyl to obtain o-chlorophenylacetonitrile, and then catalyzes the hydrogenation of cyanyl to reduce the amino group to obtain 2-chloro-phenethylamine. When catalyzing hydrogenation, the choice of catalyst, reaction pressure, temperature and other conditions are very critical, which affect the yield and purity of the product.
All synthetic methods have their own advantages and disadvantages. The practical application needs to be weighed and selected according to factors such as the availability of raw materials, cost, and ease of control of reaction conditions, so as to achieve the purpose of efficient and economical synthesis of 2-chloro-phenethylamine.
Another method uses o-chlorobenzaldehyde as the starting material. After reducing amination, it interacts with ammonia and reducing agents. For example, sodium borohydride or sodium cyanoborohydride is used as reducing agent. In an appropriate solvent, such as an alcohol solvent, 2-chloro-phenethylamine can be obtained. This process requires temperature control and reaction time to ensure complete reaction and reduce side reactions.
Furthermore, it is also possible to use o-chlorobenzyl chloride as a raw material. It first undergoes nucleophilic substitution with sodium cyanide, introduces cyanyl to obtain o-chlorophenylacetonitrile, and then catalyzes the hydrogenation of cyanyl to reduce the amino group to obtain 2-chloro-phenethylamine. When catalyzing hydrogenation, the choice of catalyst, reaction pressure, temperature and other conditions are very critical, which affect the yield and purity of the product.
All synthetic methods have their own advantages and disadvantages. The practical application needs to be weighed and selected according to factors such as the availability of raw materials, cost, and ease of control of reaction conditions, so as to achieve the purpose of efficient and economical synthesis of 2-chloro-phenethylamine.
2-chloro-benzeneethanamine what are the precautions during use
2-Chloro-phenethylamine is an organic compound. During use, many key matters must be paid attention to to to ensure safety and effectiveness.
First, safety protection must not be forgotten. This compound may be irritating and toxic. When operating, it is necessary to wear appropriate protective equipment, such as gloves, goggles, laboratory clothes, etc., to prevent skin and eye contact. If you come into contact accidentally, you should immediately rinse with plenty of water and seek medical treatment according to the specific situation. At the same time, because it may evaporate harmful gases, it is appropriate to operate in a well-ventilated environment, preferably in a fume hood to prevent inhalation of harmful gases and damage to the respiratory tract and body.
Second, storage is also exquisite. 2-Chloro-phenethylamine should be stored in a cool, dry and ventilated place, away from fire, heat and oxidants. Due to its certain chemical activity, improper storage conditions or deterioration may even cause dangerous reactions. And ensure that the storage container is well sealed to avoid leakage.
Third, the application of chemical properties needs to be cautious. When using, its chemical properties and reactivity should be clarified, and precise operation should be carried out according to the specific reaction requirements and conditions. The chlorine atoms and amino groups in the molecule of this compound are reactive and can participate in a variety of organic synthesis reactions, such as substitution reactions, condensation reactions, etc. However, different reaction conditions vary greatly, and factors such as temperature, solvent, and catalyst can all have a significant impact on the reaction process and products. Therefore, it is necessary to understand the reaction mechanism and operation process in detail before use, and strictly control the reaction conditions to ensure the smooth progress of the reaction and the quality of the product.
Fourth, waste treatment should not be underestimated. After use, the remaining 2-chloro-phenethylamine and related waste must not be discarded at will, and should be properly disposed of in accordance with local environmental protection regulations and laboratory regulations. Generally speaking, it needs to be collected by classification, and then professionally treated to ensure that its harm to the environment is minimized.
When using 2-chloro-phenethylamine, no matter what link, it is necessary to be rigorous and meticulous, and strictly follow relevant specifications and operating procedures, so as to ensure the safety of personnel and the smooth operation of experiments and production.
First, safety protection must not be forgotten. This compound may be irritating and toxic. When operating, it is necessary to wear appropriate protective equipment, such as gloves, goggles, laboratory clothes, etc., to prevent skin and eye contact. If you come into contact accidentally, you should immediately rinse with plenty of water and seek medical treatment according to the specific situation. At the same time, because it may evaporate harmful gases, it is appropriate to operate in a well-ventilated environment, preferably in a fume hood to prevent inhalation of harmful gases and damage to the respiratory tract and body.
Second, storage is also exquisite. 2-Chloro-phenethylamine should be stored in a cool, dry and ventilated place, away from fire, heat and oxidants. Due to its certain chemical activity, improper storage conditions or deterioration may even cause dangerous reactions. And ensure that the storage container is well sealed to avoid leakage.
Third, the application of chemical properties needs to be cautious. When using, its chemical properties and reactivity should be clarified, and precise operation should be carried out according to the specific reaction requirements and conditions. The chlorine atoms and amino groups in the molecule of this compound are reactive and can participate in a variety of organic synthesis reactions, such as substitution reactions, condensation reactions, etc. However, different reaction conditions vary greatly, and factors such as temperature, solvent, and catalyst can all have a significant impact on the reaction process and products. Therefore, it is necessary to understand the reaction mechanism and operation process in detail before use, and strictly control the reaction conditions to ensure the smooth progress of the reaction and the quality of the product.
Fourth, waste treatment should not be underestimated. After use, the remaining 2-chloro-phenethylamine and related waste must not be discarded at will, and should be properly disposed of in accordance with local environmental protection regulations and laboratory regulations. Generally speaking, it needs to be collected by classification, and then professionally treated to ensure that its harm to the environment is minimized.
When using 2-chloro-phenethylamine, no matter what link, it is necessary to be rigorous and meticulous, and strictly follow relevant specifications and operating procedures, so as to ensure the safety of personnel and the smooth operation of experiments and production.
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