2-Chlorobenzene-1,4-Diol
Linshang Chemical
HS Code |
574296 |
Chemical Formula | C6H5ClO2 |
Molar Mass | 144.56 g/mol |
Appearance | White to off - white solid |
Odor | May have a characteristic phenolic odor |
Melting Point | 108 - 112 °C |
Boiling Point | 255 - 257 °C |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in ethanol, ether, etc. |
Density | 1.492 g/cm³ |
Pka | Around 9.4 |
As an accredited 2-Chlorobenzene-1,4-Diol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 2 - chlorobenzene - 1,4 - diol packaged in a sealed plastic container. |
Storage | 2 - Chlorobenzene - 1,4 - diol should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and evaporation. Avoid storing near incompatible substances to prevent chemical reactions. Use appropriate storage cabinets or areas dedicated to chemicals to ensure safety. |
Shipping | 2 - chlorobenzene - 1,4 - diol is shipped in accordance with strict chemical regulations. Packed in corrosion - resistant containers, it's transported by specialized carriers, ensuring safety during transit to prevent any leakage or chemical hazards. |
Competitive 2-Chlorobenzene-1,4-Diol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 2-Chlorobenzene-1,4-Diol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Looking at its chemical activity, the hydroxyl group is active and easy to react. It can complex with metal ions, such as iron ions, or show a specific color change, just like the wonderful appearance of ancient alchemy. This property is often used for chemical identification. In addition, the hydroxyl group can undergo a substitution reaction, and the halogen atom can also participate. It is just like the ancient craftsmen who skillfully spliced parts and introduced new groups to change the properties of the compound.
Its solubility also has characteristics. It has a certain solubility in organic solvents such as ethanol and ether. It is like water soluble in oil, but its solubility in water is limited. This is due to the polar structure of the molecule.
In terms of stability, due to the interaction between chlorine atoms and hydroxyl groups, phenolic hydroxyl groups are easily oxidized, just like ancient devices that are easily corroded in the air. When exposed to oxidants, the structure is changeable, and the color or properties are also changed. And because of the presence of chlorine atoms, the electron cloud density of the benzene ring changes, which affects the overall chemical stability.
In chemical reactions, it can not only be used as a nucleophilic reagent to attack the electrophilic reagent with the electron cloud of the hydroxyl group, but also because of the benzene ring conjugated system, it can be attacked by the electrophilic reagent and participate in many organic synthesis. It is like building a complex pavilion and building a structure of new These are all important chemical properties of 2-chlorobenzene-1,4-diol, which are crucial for chemical research and industrial applications.
It is a solid at room temperature and pressure, and it may appear white to light yellow crystalline powder, which is conducive to identification and processing. Its melting point is quite critical. It is about a specific temperature range. The exact value of the melting point is of great significance to its physical state transition under different conditions. It is related to the temperature at which it melts from solid to liquid, which affects its processing and application scenarios.
On solubility, 2-chlorobenzene-1,4-diol exhibits different solubility properties in organic solvents. In some organic solvents such as ethanol and acetone, it may have a certain solubility, which makes it possible to achieve dissolution, mixing and participation in reactions in organic synthesis and related chemical operations with the help of these solvents. However, the solubility in water is relatively limited, which is related to the molecular structure and polarity of the compound. The molecular polarity is different from that of water, making it difficult to dissolve in water.
In addition, the density of 2-chlorobenzene-1,4-diol is also one of its physical properties. Although the exact density value needs to be determined by accurate measurement, this parameter is of great significance for application scenarios involving mass and volume conversion. For example, when calculating the ratio of materials and materials in chemical production, density is an important consideration. The volatile properties of 2-chlorobenzene-1,4-diol also cannot be ignored. It has a low volatility and is relatively stable at room temperature, which provides a certain guarantee for its storage and use safety, and reduces the loss and potential danger caused by volatilization.
Overall, the physical properties of 2-chlorobenzene-1,4-diol determine its application scope and operation mode in chemical, pharmaceutical and other fields. In relevant research and production practices, these properties need to be carefully considered to achieve the best use effect.
In the chemical industry, this compound is often used as an intermediate for the synthesis of other organic compounds. Due to its structure containing chlorine atoms and hydroxyl groups, it is chemically active and can be derived from many chemical reactions. For example, by means of nucleophilic substitution, chlorine atoms can be replaced by other functional groups, and then complex organic molecules can be constructed, laying the foundation for the synthesis of new materials, dyes, etc.
In the field of medicine, 2-chlorobenzene-1,4-diol also has important value. Some studies have shown that it may have a certain biological activity and can be used as a lead compound in the process of drug development. By modifying and optimizing its structure, it is expected to obtain drugs with good efficacy and small side effects. In addition, some derivatives of this compound may have antibacterial, anti-inflammatory and other properties, providing possibilities for pharmaceutical innovation.
In summary, 2-chlorobenzene-1,4-diol plays a key role in chemical synthesis and pharmaceutical research and development. With its unique chemical structure, it provides assistance for the development of many fields. It is an important compound with a wide range of uses.
First, it can be obtained from the reduction of 2-chloro-p-benzoquinone. In the past, some wise men used zinc powder and acid as an agent to make 2-chloro-p-benzoquinone go through reduction in a suitable reaction environment to obtain this 2-chlorobenzene-1,4-diol. The process needs to pay attention to the reaction temperature and the concentration of acid. If the temperature is too high, the product will be variable, and the improper concentration of acid will also affect the yield.
Second, 2-chloro-1,4-dinitrobenzene is used as the starting material. First, iron filings and hydrochloric acid are used as a reducing agent to form nitro groups into amino groups to obtain 2-chloro-1,4-phenylenediamine. Then through the method of diazotization and hydrolysis, the amino groups are converted into hydroxyl groups, and then 2-chlorobenzene-1,4-diol is obtained. During this process, the diazotization step needs to be done carefully at low temperature, otherwise the diazonium salt is easy to decompose. During hydrolysis, the conditions need to be precisely controlled to make the product come into being smoothly.
Third, hydroquinone is used as the starting material and is prepared by chlorination. However, during the chlorination process, a suitable catalyst needs to be found, and the amount of chlorine and the reaction time need to be controlled. If there is too much chlorine or the reaction time is too long, it is easy to cause the formation of polychlorinated substitutes and affect the purity of the product.
This method has its advantages and disadvantages. In the past, according to the raw materials at hand, the environment and the requirements for the product, everyone chose the best one and used it to obtain a pure and sufficient amount of 2-chlorobenzene-1,4-diol.
First and foremost, safety protection must not be forgotten. 2-chlorobenzene-1,4-diol has certain toxicity, or is absorbed through the skin, inhaled through the mouth and nose, etc., endangering human health. During operation, protective clothing, gloves and goggles must be worn, and direct contact must be strictly avoided. If you accidentally touch it, rinse it with plenty of water quickly. If the situation is serious, seek medical attention immediately. Working in a well-ventilated place is also key. Ventilation equipment can be used to disperse volatile gas in time to prevent inhalation of too many harmful substances.
Furthermore, the storage conditions must be suitable. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Because of its flammability, in case of open flame, hot topic or combustion, it needs to be stored separately from oxidants, acids, etc., and should not be mixed. The storage area should also be equipped with suitable materials to contain leaks.
During use, precise control of the dosage is indispensable. According to specific needs and reaction requirements, accurately weigh an appropriate amount of 2-chlorobenzene-1,4-diol to ensure the reaction effect and avoid waste and environmental pollution. Proper disposal of the residue after use should not be discarded at will, and relevant regulations should be followed for harmless treatment.
In addition, it is also important to be familiar with emergency treatment methods. In the event of a leak, quickly evacuate personnel from the contaminated area of the leak to a safe area, isolate them, and strictly restrict access. Emergency personnel wear self-contained positive pressure breathing apparatus and anti-toxic clothing to cut off the source of the leak as much as possible. Small leaks: Mix with sand, dry lime or soda ash. You can also rinse with a lot of water, dilute the washing water and put it into the wastewater system. Large leaks: Build a dike or dig a pit for containment. Transfer to a tanker or a special collector by pump, recycle or transport to a waste treatment site for disposal.
In short, when using 2-chlorobenzene-1,4-diol, be careful and follow strict regulations to ensure safety and avoid accidents.

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