Linshang Chemical
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2-Chlorobenzene-1-Carbohydrazide
Linshang Chemical
|
HS Code |
196683 |
| Chemical Formula | C7H7ClN2O |
| Molar Mass | 170.597 g/mol |
| Appearance | Solid |
| Odor | May have a characteristic odor |
| Melting Point | 125 - 128 °C |
| Solubility In Water | Poorly soluble |
| Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, chloroform |
| Density | Data may vary, typical organic solid density range |
| Purity | Can be of different purities commercially available, e.g., 95%+ |
| Stability | Stable under normal conditions, may decompose on heating or under certain chemical environments |
As an accredited 2-Chlorobenzene-1-Carbohydrazide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 2 - chlorobenzene - 1 - carbohydrazide packaged in a sealed plastic bag. |
| Storage | 2 - Chlorobenzene - 1 - carbohydrazide should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances such as strong oxidizing agents. Store it in a tightly closed container to prevent moisture absorption and contamination, ensuring its stability and integrity for future use. |
| Shipping | 2 - chlorobenzene - 1 - carbohydrazide is shipped in sealed, corrosion - resistant containers. These are carefully packed to prevent damage. Shipments follow strict chemical transportation regulations to ensure safety during transit. |
Competitive 2-Chlorobenzene-1-Carbohydrazide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2-Chlorobenzene-1-Carbohydrazide in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2-Chlorobenzene-1-Carbohydrazide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 2-chlorobenzene-1-carbohydrazide?
2-Chlorobenzene-1-formylhydrazide is one of the organic compounds. Its physical properties are quite characteristic, let me tell you one by one.
Looking at its appearance, at room temperature, it is mostly white to white crystalline powder. This form is easy to identify and handle, and the surface area of the powdered material is large, and it may be more active in some reactions.
When it comes to the melting point, it is about a specific temperature range. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of 2-chlorobenzene-1-formylhydrazide is an important indicator to identify its purity and characteristics. If the purity is high, the melting point is relatively fixed and close to the theoretical value; if it contains impurities, the melting point may be deviated.
As for the solubility, this substance varies in different solvents. In common organic solvents such as ethanol and acetone, there is a certain solubility. This property allows it to be used in organic synthesis and other fields. When used in organic synthesis, a suitable solvent can be selected according to the reaction requirements to promote the reaction, or to achieve its separation and purification. In water, its solubility is relatively limited. This is because the molecular structure of the compound, although there are groups that can interact with water molecules, the molecular polarity of the whole is not well matched with water molecules, so it is difficult to dissolve in water.
In addition, the stability of 2-chlorobenzene-1-formylhydrazide is also one of its important physical properties. It can remain relatively stable in a dry environment at room temperature and pressure, protected from light. However, in case of extreme conditions such as high temperature, strong oxidants or strong acids and bases, its structure may change, resulting in changes in properties. This stability feature requires special attention when storing and using the substance to ensure that its quality and performance are not affected.
Looking at its appearance, at room temperature, it is mostly white to white crystalline powder. This form is easy to identify and handle, and the surface area of the powdered material is large, and it may be more active in some reactions.
When it comes to the melting point, it is about a specific temperature range. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of 2-chlorobenzene-1-formylhydrazide is an important indicator to identify its purity and characteristics. If the purity is high, the melting point is relatively fixed and close to the theoretical value; if it contains impurities, the melting point may be deviated.
As for the solubility, this substance varies in different solvents. In common organic solvents such as ethanol and acetone, there is a certain solubility. This property allows it to be used in organic synthesis and other fields. When used in organic synthesis, a suitable solvent can be selected according to the reaction requirements to promote the reaction, or to achieve its separation and purification. In water, its solubility is relatively limited. This is because the molecular structure of the compound, although there are groups that can interact with water molecules, the molecular polarity of the whole is not well matched with water molecules, so it is difficult to dissolve in water.
In addition, the stability of 2-chlorobenzene-1-formylhydrazide is also one of its important physical properties. It can remain relatively stable in a dry environment at room temperature and pressure, protected from light. However, in case of extreme conditions such as high temperature, strong oxidants or strong acids and bases, its structure may change, resulting in changes in properties. This stability feature requires special attention when storing and using the substance to ensure that its quality and performance are not affected.
What are the chemical properties of 2-chlorobenzene-1-carbohydrazide?
2-Chlorobenzene-1-formylhydrazide, an organic compound. It has many unique chemical properties, so let me explain in detail for you.
From the structural point of view, the molecule contains a benzene ring, which endows it with certain stability and conjugation properties. The presence of chlorine atoms on the benzene ring significantly affects the distribution of its electron cloud. Chlorine atoms have an electron-absorbing induction effect, which can reduce the electron cloud density of the benzene ring and change the activity of the electrophilic substitution reaction of the benzene ring. Compared with benzene, it is more difficult to undergo electrophilic substitution, and the substitution position is affected by the positioning effect of chlorine atoms, which tends to react in the adjacent and para-positions of the chlorine atom. The formylhydrazide part of the
molecule, the -CONHNH 2O group is rich in atoms with lone pair electrons such as nitrogen and oxygen, which makes it have certain alkalinity and coordination ability. The lone pair electrons of nitrogen atoms can bind to protons, showing weak alkalinity. This group can also coordinate with metal ions to form complexes, which may have applications in catalysis, materials science and other fields.
2-chlorobenzene-1-formylhydrazide also has certain reactivity. The formylhydrazide part can react with aldons and ketones to form hydrazone compounds. This reaction is often used in organic synthesis to construct nitrogen-containing heterocycles or organic molecules with special structures. Under appropriate conditions, it can also undergo hydrolysis reaction, and the formyl hydrazide group is disconnected to form the corresponding carboxylic acid and hydrazine derivatives.
In addition, 2-chlorobenzene-1-formyl hydrazide has unique solubility in organic solvents and water due to the coexistence of benzene ring and polar group in the structure. Moderate polar organic solvents may have good solubility to it, but its solubility in water is relatively limited, but due to the polarity of the formyl hydrazide group, it may have a certain dispersion in water. This solubility characteristic needs to be taken into account when separating, purifying and selecting the reaction medium.
From the structural point of view, the molecule contains a benzene ring, which endows it with certain stability and conjugation properties. The presence of chlorine atoms on the benzene ring significantly affects the distribution of its electron cloud. Chlorine atoms have an electron-absorbing induction effect, which can reduce the electron cloud density of the benzene ring and change the activity of the electrophilic substitution reaction of the benzene ring. Compared with benzene, it is more difficult to undergo electrophilic substitution, and the substitution position is affected by the positioning effect of chlorine atoms, which tends to react in the adjacent and para-positions of the chlorine atom. The formylhydrazide part of the
molecule, the -CONHNH 2O group is rich in atoms with lone pair electrons such as nitrogen and oxygen, which makes it have certain alkalinity and coordination ability. The lone pair electrons of nitrogen atoms can bind to protons, showing weak alkalinity. This group can also coordinate with metal ions to form complexes, which may have applications in catalysis, materials science and other fields.
2-chlorobenzene-1-formylhydrazide also has certain reactivity. The formylhydrazide part can react with aldons and ketones to form hydrazone compounds. This reaction is often used in organic synthesis to construct nitrogen-containing heterocycles or organic molecules with special structures. Under appropriate conditions, it can also undergo hydrolysis reaction, and the formyl hydrazide group is disconnected to form the corresponding carboxylic acid and hydrazine derivatives.
In addition, 2-chlorobenzene-1-formyl hydrazide has unique solubility in organic solvents and water due to the coexistence of benzene ring and polar group in the structure. Moderate polar organic solvents may have good solubility to it, but its solubility in water is relatively limited, but due to the polarity of the formyl hydrazide group, it may have a certain dispersion in water. This solubility characteristic needs to be taken into account when separating, purifying and selecting the reaction medium.
What are the main uses of 2-chlorobenzene-1-carbohydrazide?
2-Chlorobenzene-1-formylhydrazide is an organic compound. It has a wide range of uses and is often used as a key intermediate in drug synthesis. Molecular structures with specific biological activities can be constructed by specific reaction pathways to develop new drugs or optimize the performance of existing drugs, improve efficacy and reduce side effects.
In terms of pesticides, it is also an important synthetic raw material. It can be chemically converted to prepare pesticide products with insecticidal, bactericidal, herbicide and other effects, which can help agricultural production, resist pest attacks, and ensure crop yield and quality.
In the field of materials science, 2-chlorobenzene-1-formylhydrazide can participate in material modification related reactions. After proper treatment, the material is endowed with characteristics such as better stability and corrosion resistance, thus expanding the application scenarios of the material, which can play a role in many fields such as aerospace and electronic devices.
At the same time, in the field of scientific research and exploration, due to its unique chemical structure and reactivity, it is often used by researchers in the study of new chemical reaction mechanisms, providing important experimental basis and theoretical support for the development of organic synthetic chemistry, promoting the continuous progress of chemistry and opening up more unknown fields.
In terms of pesticides, it is also an important synthetic raw material. It can be chemically converted to prepare pesticide products with insecticidal, bactericidal, herbicide and other effects, which can help agricultural production, resist pest attacks, and ensure crop yield and quality.
In the field of materials science, 2-chlorobenzene-1-formylhydrazide can participate in material modification related reactions. After proper treatment, the material is endowed with characteristics such as better stability and corrosion resistance, thus expanding the application scenarios of the material, which can play a role in many fields such as aerospace and electronic devices.
At the same time, in the field of scientific research and exploration, due to its unique chemical structure and reactivity, it is often used by researchers in the study of new chemical reaction mechanisms, providing important experimental basis and theoretical support for the development of organic synthetic chemistry, promoting the continuous progress of chemistry and opening up more unknown fields.
What is 2-chlorobenzene-1-carbohydrazide synthesis method?
The synthesis of 2-chlorobenzene-1-formylhydrazide is an important topic in the field of chemistry. There are various methods, such as using 2-chlorobenzoic acid as the starting material. First, 2-chlorobenzoic acid is reacted with thionyl chloride, and the carboxyl group can be converted into an acid chloride in this step. Sulfuryl chloride is mixed with 2-chlorobenzoic acid and heated properly to react to form 2-chlorobenzoyl chloride, while sulfur dioxide and hydrogen chloride gas escape.
Then, 2-chlorobenzoyl chloride is reacted with hydrazine hydrate. 2-Chlorobenzoyl chloride is slowly dropped into the solution of hydrazine hydrate. Under suitable temperature and stirring conditions, the nucleophilic substitution reaction between the acid chloride and the amino group of hydrazine hydrate occurs to obtain 2-chlorobenzene-1-formylhydrazide. After the reaction, the pure product can be obtained through post-processing steps such as filtration, washing, and recrystallization.
Another method is to use 2-chlorobenzonitrile as a raw material. First, 2-chlorobenzonitrile is hydrolyzed under alkaline conditions to produce 2-chlorobenzoate, and then acidified to obtain 2-chlorobenzoic acid. The following steps are the same as those using 2-chlorobenzoic acid as the starting material, that is, the acid chloride is first prepared, and then reacted with hydrazine hydrate to obtain the target product. This synthesis process requires attention to the control of reaction conditions, temperature, proportion of reactants and other factors, which all affect the yield and purity of the product. In this way, through a series of steps, 2-chlorobenzene-1-formylhydrazide can be obtained.
Then, 2-chlorobenzoyl chloride is reacted with hydrazine hydrate. 2-Chlorobenzoyl chloride is slowly dropped into the solution of hydrazine hydrate. Under suitable temperature and stirring conditions, the nucleophilic substitution reaction between the acid chloride and the amino group of hydrazine hydrate occurs to obtain 2-chlorobenzene-1-formylhydrazide. After the reaction, the pure product can be obtained through post-processing steps such as filtration, washing, and recrystallization.
Another method is to use 2-chlorobenzonitrile as a raw material. First, 2-chlorobenzonitrile is hydrolyzed under alkaline conditions to produce 2-chlorobenzoate, and then acidified to obtain 2-chlorobenzoic acid. The following steps are the same as those using 2-chlorobenzoic acid as the starting material, that is, the acid chloride is first prepared, and then reacted with hydrazine hydrate to obtain the target product. This synthesis process requires attention to the control of reaction conditions, temperature, proportion of reactants and other factors, which all affect the yield and purity of the product. In this way, through a series of steps, 2-chlorobenzene-1-formylhydrazide can be obtained.
What are the precautions in storage and transportation of 2-chlorobenzene-1-carbohydrazide?
2-Chlorobenzene-1-formyl hydrazide is an organic compound. During storage and transportation, the following matters must be paid attention to:
First, when storing, it must be cool, dry and well ventilated. Because it may be sensitive to humidity and temperature, it is easy to deteriorate in a high temperature and humid environment. If it is in a humid place or reacts with water vapor, it will affect its quality; under high temperature, it may cause a chemical reaction and damage its chemical properties.
Second, this compound needs to be kept away from fires and heat sources. Because of its flammability, it is dangerous to burn and explode in case of open flames and hot topics. In the storage area, smoking and open flames are strictly prohibited, and suitable fire equipment should be equipped to prepare for emergencies.
Third, it should be stored separately from oxidizing agents, acids, alkalis, etc., and must not be mixed. The chemical properties of 2-chlorobenzene-1-formylhydrazide make it easy to chemically react with the above substances, or cause serious accidents such as fire and explosion.
Fourth, when transporting, make sure that the container does not leak, collapse, fall, or damage. Because it is a chemical product, once the container is damaged, the material leaks, or pollutes the environment, endangering personal safety.
Fifth, the transportation vehicle must be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In case of emergency on the way, it can be responded to in time to reduce the harm. And the transportation process should be driven according to the specified route, do not stop in densely populated areas and residential areas.
Sixth, operators must undergo special training and strictly abide by the operating procedures. When loading and unloading, light handling is required to prevent damage to packaging and containers. Smoking, eating and drinking should be avoided at the operation site, and thorough cleaning should be done after the operation.
All these precautions are to ensure the safety of 2-chlorobenzene-1-formylhydrazide during storage and transportation, avoid accidents, and ensure the safety of personnel and the environment from pollution.
First, when storing, it must be cool, dry and well ventilated. Because it may be sensitive to humidity and temperature, it is easy to deteriorate in a high temperature and humid environment. If it is in a humid place or reacts with water vapor, it will affect its quality; under high temperature, it may cause a chemical reaction and damage its chemical properties.
Second, this compound needs to be kept away from fires and heat sources. Because of its flammability, it is dangerous to burn and explode in case of open flames and hot topics. In the storage area, smoking and open flames are strictly prohibited, and suitable fire equipment should be equipped to prepare for emergencies.
Third, it should be stored separately from oxidizing agents, acids, alkalis, etc., and must not be mixed. The chemical properties of 2-chlorobenzene-1-formylhydrazide make it easy to chemically react with the above substances, or cause serious accidents such as fire and explosion.
Fourth, when transporting, make sure that the container does not leak, collapse, fall, or damage. Because it is a chemical product, once the container is damaged, the material leaks, or pollutes the environment, endangering personal safety.
Fifth, the transportation vehicle must be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In case of emergency on the way, it can be responded to in time to reduce the harm. And the transportation process should be driven according to the specified route, do not stop in densely populated areas and residential areas.
Sixth, operators must undergo special training and strictly abide by the operating procedures. When loading and unloading, light handling is required to prevent damage to packaging and containers. Smoking, eating and drinking should be avoided at the operation site, and thorough cleaning should be done after the operation.
All these precautions are to ensure the safety of 2-chlorobenzene-1-formylhydrazide during storage and transportation, avoid accidents, and ensure the safety of personnel and the environment from pollution.
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