2-Chlorobenzenesulfonamide

Linshang Chemical

Specifications

HS Code

742508

Chemical Formula C6H6ClNO2S
Molecular Weight 191.63
Appearance Solid
Odor May have a characteristic odor
Melting Point Data varies, check literature
Boiling Point Data varies, check literature
Solubility In Water Low solubility in water
Solubility In Organic Solvents Soluble in some organic solvents
Density Data varies, check literature
Pka Data varies, check literature

As an accredited 2-Chlorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - chlorobenzenesulfonamide packaged in a sealed plastic - lined paper bag.
Storage 2 - Chlorobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances such as strong oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and contamination. Ensure the storage location is clearly labeled for easy identification and safety.
Shipping 2 - Chlorobenzenesulfonamide is shipped in accordance with strict chemical regulations. It's packaged securely in appropriate containers to prevent leakage. Shipments are handled with care, ensuring compliance with safety and environmental standards during transit.
Free Quote

Competitive 2-Chlorobenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365006308

Email: info@alchemist-chem.com

2-Chlorobenzenesulfonamide 2-Chlorobenzenesulfonamide
General Information
Where to Buy 2-Chlorobenzenesulfonamide in China?
As a trusted 2-Chlorobenzenesulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2-Chlorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of 2-chlorobenzenesulfonamide?
2-Chlorobenzenesulfonamide is one of the organic compounds. It is active and can show its unique properties in chemical reactions.
In terms of its physical properties, it is mostly solid at room temperature, colored or nearly white, and has a certain melting point and boiling point. Its melting point is within a specific range, and this value depends on the compactness of its structure and the strength of intermolecular forces. The boiling point is also related to it, reflecting the energy required for the molecule to break free.
As for chemical properties, sulfonamide groups are an important active site. Because nitrogen atoms have lone pairs of electrons, they can be used as nucleophiles and react with many electrophiles. In an acidic environment, nitrogen atoms can be protonated, causing its chemical activity to change.
Furthermore, chlorine atoms are attached to the benzene ring, which makes the electron cloud density of the benzene ring uneven. Chlorine has strong electronegativity and significant electron induction effect, which affects the electrophilic substitution reaction on the benzene ring. Generally speaking, chlorine atoms are ortho and para-sites, so that electrophilic substitution mostly occurs in the ortho and para-sites.
2 -chlorobenzenesulfonamide can also participate in a variety of organic synthesis reactions, such as condensation with amine compounds to form new nitrogen-containing compounds. It is important in the fields of drug synthesis and materials science. Its diverse chemical properties provide a broad space for the expansion of organic synthesis.
What are the main uses of 2-chlorobenzenesulfonamide?
2-Chlorobenzenesulfonamide is one of the organic compounds with a wide range of uses. In the field of medicine, this substance is often used as a key intermediate to create many drugs. For example, in the synthesis of some antibacterial drugs, the properties of 2-chlorobenzenesulfonamide can help it combine with specific targets to exert antibacterial effects to resist bacterial damage to the human body and protect health.
In the field of pesticides, 2-chlorobenzenesulfonamide also has important uses. It can be used as a raw material to produce pesticide products with insecticidal and herbicidal properties. For example, for specific weeds, it can interfere with the physiological and metabolic processes of weeds, inhibit the growth of weeds, thereby ensuring the growth space and nutrient acquisition of crops in the field, and improve the yield and quality of crops.
In the field of materials science, 2-chlorobenzenesulfonamide also plays a unique role. It can be used to synthesize special polymer materials. By polymerizing with other monomers, the polymer materials are endowed with special physical and chemical properties, such as enhancing the stability and corrosion resistance of the materials, so that the materials are suitable for more complex and harsh environments and meet the needs of different industrial scenarios.
Furthermore, in the laboratory research of organic synthetic chemistry, 2-chlorobenzenesulfonamide is often an important reagent. Researchers use it to participate in various organic reactions to construct more complex organic molecular structures, providing an important way for the research and development and exploration of new compounds, and promoting the sustainable development and progress of organic chemistry.
What are 2-chlorobenzenesulfonamide synthesis methods?
The synthesis methods of 2-chlorobenzenesulfonamide cover many kinds. The ancient synthesis method, or starting from benzenesulfonamide, is obtained by halogenation. The halogenation method often uses chlorine as a halogenating agent. Under suitable conditions, chlorine atoms are introduced into specific positions on the benzene ring of benzenesulfonamide. In this process, the control of reaction conditions is very important, such as temperature, solvent selection, and catalyst, which can all affect the yield and purity of the product.
There are also those who use o-chlorobenzenesulfonic acid as a raw material to react with ammonia or amine compounds. When o-chlorobenzenesulfonic acid reacts with ammonia, the sulfonic acid group reacts with ammonia to form 2-chlorobenzenesulfonamide. In this reaction, factors such as the amount of ammonia, reaction time and temperature all affect the process of the reaction and the quality of the product.
Furthermore, it can be synthesized from o-chloroaniline through a series of steps such as diazotization and Sandmeier reaction. First, o-chloroaniline is denitrified to obtain a diazonium salt, and then under the Sandmeier reaction conditions, the copper salt is used as a catalyst to react with sulfur dioxide and chloride to form 2-chlorobenzenesulfonyl chloride, and finally reacts with ammonia to obtain 2-chlorobenzenesulfonamide. Although this route is complex, if the conditions of each step can be well regulated, the product with higher yield and purity can also be obtained.
The above synthesis methods have their own advantages and disadvantages, and they need to be selected according to actual needs, such as the ease of obtaining raw materials, cost considerations, and product purity requirements.
2-chlorobenzenesulfonamide What are the precautions in storage and transportation?
2-Chlorobenzenesulfonamide is an organic compound. During storage and transportation, many matters must be paid attention to.
Bear the brunt, and the storage environment must be dry and cool. This substance is afraid of moisture and heat. Humidity can easily cause hydrolysis and deterioration, and high temperature may cause chemical reactions, or even lead to danger. Therefore, it should be stored in a well-ventilated place with suitable temperature, away from heat sources and water sources.
Secondly, it needs to be stored separately from oxidants, acids, bases, etc. Because of its active chemical properties, contact with the above substances is prone to violent reactions, or serious consequences such as fire and explosion. In the storage area, it should be clearly marked and stored in strict zones.
Furthermore, the packaging must be tight. Ensure that the packaging materials are of high quality, without damage or leakage. High-quality packaging can not only prevent external factors from affecting 2-chlorobenzenesulfonamide, but also avoid its leakage from causing harm to the environment and personnel.
As for transportation, it is necessary to choose a means of transportation that meets the regulations. Transportation vehicles should have corresponding protective facilities to deal with possible unexpected situations. During transportation, keep smooth driving, avoid bumps and vibrations, and prevent packaging damage. At the same time, transportation personnel should be familiar with the characteristics of 2-chlorobenzenesulfonamide and emergency treatment methods. In the event of an emergency such as a leak, they can deal with it quickly and properly.
In conclusion, the storage and transportation of 2-chlorobenzenesulfonamide requires strict treatment, following relevant regulations and operating procedures to ensure that personnel safety and the environment are not damaged.
2-chlorobenzenesulfonamide impact on the environment and human health
2-Chlorobenzenesulfonamide, the impact on the environment and human health, should be discussed in detail now.
First talk about its impact on the environment. 2-Chlorobenzenesulfonamide can cause water pollution if it flows into natural water bodies. Its chemical properties are stable, difficult to be naturally degraded, or long-term retention in water bodies. Aquatic organisms, such as fish and shrimp, if exposed to this substance, may cause physiological disorders. It may interfere with the endocrine system of aquatic organisms, impair reproductive function, and affect population reproduction. In the soil environment, if 2-chlorobenzenesulfonamide accumulates too much, it may change soil physicochemical properties, inhibit soil microbial activity, and then affect nutrient cycling in the soil and plant root absorption of nutrients, causing vegetation growth to be hindered.
Describe its impact on human health. Inhalation of air containing 2-chlorobenzenesulfonamide through the respiratory tract, or skin contact, accidental ingestion of food and water containing this substance can cause health hazards. In the human body, it may affect the immune system and weaken the body's ability to resist diseases. Studies have also shown that this substance may be potentially carcinogenic, and long-term exposure may increase the risk of cancer. And it may have adverse effects on the nervous system, causing symptoms such as headache, dizziness, memory loss, etc., affecting people's normal life and work. Therefore, 2-chlorobenzenesulfonamide has many potential hazards to the environment and human health, and it should be treated with caution and its production, use and discharge should be strictly controlled to protect the environment and human health.