Linshang Chemical
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(2-Chloroehyl)Benzene
Linshang Chemical
|
HS Code |
897941 |
| Chemical Formula | C8H9Cl |
| Molar Mass | 140.61 g/mol |
| Appearance | Colorless to light - yellow liquid |
| Odor | Aromatic odor |
| Density | 1.069 g/cm³ (at 20 °C) |
| Boiling Point | 197 - 199 °C |
| Melting Point | -43 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in most organic solvents |
| Vapor Pressure | 0.13 kPa at 29.2 °C |
| Flash Point | 72 °C |
As an accredited (2-Chloroehyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | (2 - chloroethyl)benzene packaged in 5 - liter containers. |
| Storage | (2 - chloroethyl)benzene should be stored in a cool, well - ventilated area, away from heat and ignition sources. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents, strong acids, and bases to avoid chemical reactions. Use appropriate storage cabinets or areas compliant with safety regulations for this flammable and potentially hazardous chemical. |
| Shipping | (2 - chloroethyl)benzene is shipped in accordance with hazardous chemical regulations. It's typically transported in specialized containers, ensuring proper containment to prevent leakage and comply with safety and environmental standards during transit. |
Competitive (2-Chloroehyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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What are the chemical properties of (2-chloroethyl) benzene
(2-Chloroethyl) benzene is also an organic compound. In its molecular structure, the benzene ring is connected to the 2-chloroethyl group. The chemical properties of this compound are unique and valuable to explore.
In terms of its chemical activity, the presence of chlorine atoms makes the 2-chloroethyl part exhibit certain electrophilicity. Chlorine atoms have an electron-absorbing induction effect, which can reduce the electron cloud density of the carbon atoms connected to them, and then make them vulnerable to attack by nucleophiles. In case of nucleophiles such as hydroxyl negative ions, chlorine atoms can be replaced to form new compounds containing hydroxyl groups. In the field of organic synthesis, this substitution reaction is often an important way to construct new carbon-oxygen bonds or carbon-nitrogen bonds.
Furthermore, the presence of benzene rings also endows (2-chloroethyl) benzene with special chemical properties. The benzene ring has a conjugated system and its properties are relatively stable. However, under appropriate conditions, various reactions can also occur. For example, under the catalysis of Lewis acid, it can undergo Fu-gram alkylation with haloalkanes, introducing new alkyl substituents on the benzene ring. Or under the action of specific oxidants, the benzene ring can be oxidized to form oxygen-containing compounds.
In addition, the halogenation reaction of (2-chloroethyl) benzene is also worthy of attention. Due to the characteristics of electron cloud density distribution on the benzene ring, halogen atoms can selectively replace hydrogen atoms on the benzene ring to form halogenated products at different positions. The selectivity of this reaction is closely related to the reaction conditions and the type of catalyst.
In short, (2-chloroethyl) benzene has a unique molecular structure and rich and diverse chemical properties, and has a wide range of applications and research values in organic synthesis, pharmaceutical chemistry and many other fields.
In terms of its chemical activity, the presence of chlorine atoms makes the 2-chloroethyl part exhibit certain electrophilicity. Chlorine atoms have an electron-absorbing induction effect, which can reduce the electron cloud density of the carbon atoms connected to them, and then make them vulnerable to attack by nucleophiles. In case of nucleophiles such as hydroxyl negative ions, chlorine atoms can be replaced to form new compounds containing hydroxyl groups. In the field of organic synthesis, this substitution reaction is often an important way to construct new carbon-oxygen bonds or carbon-nitrogen bonds.
Furthermore, the presence of benzene rings also endows (2-chloroethyl) benzene with special chemical properties. The benzene ring has a conjugated system and its properties are relatively stable. However, under appropriate conditions, various reactions can also occur. For example, under the catalysis of Lewis acid, it can undergo Fu-gram alkylation with haloalkanes, introducing new alkyl substituents on the benzene ring. Or under the action of specific oxidants, the benzene ring can be oxidized to form oxygen-containing compounds.
In addition, the halogenation reaction of (2-chloroethyl) benzene is also worthy of attention. Due to the characteristics of electron cloud density distribution on the benzene ring, halogen atoms can selectively replace hydrogen atoms on the benzene ring to form halogenated products at different positions. The selectivity of this reaction is closely related to the reaction conditions and the type of catalyst.
In short, (2-chloroethyl) benzene has a unique molecular structure and rich and diverse chemical properties, and has a wide range of applications and research values in organic synthesis, pharmaceutical chemistry and many other fields.
What are the main uses of (2-chloroethyl) benzene
(2-Chloroethyl) benzene is one of the organic compounds with a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Through a series of chemical reactions, it can be converted into other important organic compounds. If it interacts with nucleophiles, new carbon-carbon bonds or carbon-heteroatomic bonds can be formed, laying the foundation for the construction of complex organic molecular structures.
In materials science, (2-chloroethyl) benzene also plays an important role. It can participate in the preparation of special polymer materials. After polymerization, its structural units are introduced into the polymer chain, giving the material unique properties, such as improving the solubility, thermal stability and mechanical properties of the material, to meet the strict requirements of material properties in different application scenarios.
In the field of pharmaceutical chemistry, (2-chloroethyl) benzene also shows important value. As a pharmaceutical intermediate, it can be used to synthesize drug molecules with specific biological activities. It can be seen in the synthesis path of many drugs. By modifying and modifying its structure, innovative drugs with different pharmacological effects can be developed, making contributions to human health.
In addition, in the fragrance industry, (2-chloroethyl) benzene can be used as a raw material for synthesizing fragrances. After ingenious chemical reactions, compounds with unique aromas are generated, which are used to prepare various flavors and fragrances, add the aroma charm of products, and are widely used in perfumes, cosmetics, food and other industries to enhance product quality and market competitiveness.
In materials science, (2-chloroethyl) benzene also plays an important role. It can participate in the preparation of special polymer materials. After polymerization, its structural units are introduced into the polymer chain, giving the material unique properties, such as improving the solubility, thermal stability and mechanical properties of the material, to meet the strict requirements of material properties in different application scenarios.
In the field of pharmaceutical chemistry, (2-chloroethyl) benzene also shows important value. As a pharmaceutical intermediate, it can be used to synthesize drug molecules with specific biological activities. It can be seen in the synthesis path of many drugs. By modifying and modifying its structure, innovative drugs with different pharmacological effects can be developed, making contributions to human health.
In addition, in the fragrance industry, (2-chloroethyl) benzene can be used as a raw material for synthesizing fragrances. After ingenious chemical reactions, compounds with unique aromas are generated, which are used to prepare various flavors and fragrances, add the aroma charm of products, and are widely used in perfumes, cosmetics, food and other industries to enhance product quality and market competitiveness.
What are the synthesis methods of (2-chloroethyl) benzene
The synthesis method of (2-chloroethyl) benzene has existed in ancient times and is described in this article.
First, benzene and chloroethanol are used as raw materials, and appropriate catalysts, such as aluminum trichloride, can be used to form this compound under suitable temperature and reaction conditions. This reaction is an electrophilic substitution reaction. The benzene ring is electron-rich. The hydroxyl group of chloroethanol acts as a catalyst to form an electrophilic intermediate, attacks the benzene ring, and undergoes a substitution reaction to obtain (2-chloroethyl) benzene.
Second, ethylene and hydrogen chloride can be added to obtain chloroethane first, and then benzene and chloroethane can be used as raw materials. In the presence of a catalyst, it is prepared by an alkylation reaction of Fu-g. This reaction requires attention to control the reaction conditions, because the Fu-gram alkylation reaction is prone to polyalkylation side reactions, which affect the purity of the product. Therefore, the appropriate amount of catalyst, reaction temperature and time must be selected to improve the yield of the target product.
Third, the reaction of phenylethanol with chlorination reagents can also be achieved. Commonly used chlorination reagents such as thionyl chloride, phosphorus trichloride, etc. The hydroxyl group of phenylethanol reacts with the chlorination reagent, and the hydroxyl group is replaced by the chlorine atom to obtain (2-chloroethyl) benzene. This method has relatively mild reaction conditions and is relatively easy to operate.
All synthetic methods have their own advantages and disadvantages. In practical application, the most suitable method should be selected based on factors such as the availability of raw materials, cost, and product purity requirements.
First, benzene and chloroethanol are used as raw materials, and appropriate catalysts, such as aluminum trichloride, can be used to form this compound under suitable temperature and reaction conditions. This reaction is an electrophilic substitution reaction. The benzene ring is electron-rich. The hydroxyl group of chloroethanol acts as a catalyst to form an electrophilic intermediate, attacks the benzene ring, and undergoes a substitution reaction to obtain (2-chloroethyl) benzene.
Second, ethylene and hydrogen chloride can be added to obtain chloroethane first, and then benzene and chloroethane can be used as raw materials. In the presence of a catalyst, it is prepared by an alkylation reaction of Fu-g. This reaction requires attention to control the reaction conditions, because the Fu-gram alkylation reaction is prone to polyalkylation side reactions, which affect the purity of the product. Therefore, the appropriate amount of catalyst, reaction temperature and time must be selected to improve the yield of the target product.
Third, the reaction of phenylethanol with chlorination reagents can also be achieved. Commonly used chlorination reagents such as thionyl chloride, phosphorus trichloride, etc. The hydroxyl group of phenylethanol reacts with the chlorination reagent, and the hydroxyl group is replaced by the chlorine atom to obtain (2-chloroethyl) benzene. This method has relatively mild reaction conditions and is relatively easy to operate.
All synthetic methods have their own advantages and disadvantages. In practical application, the most suitable method should be selected based on factors such as the availability of raw materials, cost, and product purity requirements.
What are the precautions for (2-chloroethyl) benzene in storage and transportation?
For (2-chloroethyl) benzene, there are many precautions to keep in mind when storing and transporting.
This chemical is toxic and must be stored in a cool and ventilated warehouse. Because of the cool and ventilated place, it can avoid high temperature causing its volatilization to intensify or cause chemical reactions. The temperature of the warehouse should be controlled within a reasonable range and should not be too high to prevent danger. And keep away from fire and heat sources. Open flames and hot topics can cause combustion and explosion, which is the most important thing.
Furthermore, it should be stored separately from oxidants and edible chemicals, and should not be mixed. Due to its active chemical properties, it is easy to react violently when in contact with oxidants, endangering safety; it is mixed with edible chemicals, and in case of leakage, it may cause serious consequences such as accidental ingestion.
During transportation, there are also many precautions. The transportation vehicle must be clean and free of other chemicals to avoid adverse reactions with it. And the transportation process needs to be stable and slow to prevent the package from being damaged due to bumps and collisions, resulting in leakage of (2-chloroethyl) benzene.
Packaging is also crucial, and it must be tightly sealed with suitable packaging materials. Such as strong barrels or bottles, to prevent leakage due to poor packaging during transportation. In the event of leakage, emergency measures should be taken quickly to evacuate the surrounding people and isolate the leakage area. Do not panic.
In short, the storage and transportation of (2-chloroethyl) benzene, from environmental control to packaging and transportation, are all about safety, and must not be sloppy at all. Only by following regulations can we be safe.
This chemical is toxic and must be stored in a cool and ventilated warehouse. Because of the cool and ventilated place, it can avoid high temperature causing its volatilization to intensify or cause chemical reactions. The temperature of the warehouse should be controlled within a reasonable range and should not be too high to prevent danger. And keep away from fire and heat sources. Open flames and hot topics can cause combustion and explosion, which is the most important thing.
Furthermore, it should be stored separately from oxidants and edible chemicals, and should not be mixed. Due to its active chemical properties, it is easy to react violently when in contact with oxidants, endangering safety; it is mixed with edible chemicals, and in case of leakage, it may cause serious consequences such as accidental ingestion.
During transportation, there are also many precautions. The transportation vehicle must be clean and free of other chemicals to avoid adverse reactions with it. And the transportation process needs to be stable and slow to prevent the package from being damaged due to bumps and collisions, resulting in leakage of (2-chloroethyl) benzene.
Packaging is also crucial, and it must be tightly sealed with suitable packaging materials. Such as strong barrels or bottles, to prevent leakage due to poor packaging during transportation. In the event of leakage, emergency measures should be taken quickly to evacuate the surrounding people and isolate the leakage area. Do not panic.
In short, the storage and transportation of (2-chloroethyl) benzene, from environmental control to packaging and transportation, are all about safety, and must not be sloppy at all. Only by following regulations can we be safe.
What are the effects of (2-chloroethyl) benzene on the environment and human health?
The impact of (2-chloroethyl) benzene on the environment and human health is of paramount importance.
At the environmental end, (2-chloroethyl) benzene has a certain volatility and can escape into the atmosphere. In the atmosphere, it may participate in photochemical reactions, which may disturb the chemical composition of the atmosphere, thereby affecting air quality. And if it settles into soil and water bodies through processes such as rainwater initialization, in soil, it may affect the community structure and function of soil microorganisms and hinder the normal recycling of substances in soil; in water bodies, it will endanger aquatic organisms. Due to its toxicity, it may cause the growth and reproduction of aquatic organisms to be trapped, and even cause the death of some sensitive species, thereby destroying the balance of aquatic ecosystems.
As for human health, (2-chloroethyl) benzene can invade the human body through respiratory tract, skin contact and other pathways. After entering the body, it may cause damage to the nervous system, causing headaches, dizziness, fatigue, drowsiness and other discomforts. Long-term exposure may involve important organs such as the liver and kidneys, affecting their normal metabolism and detoxification functions. In addition, studies have shown that (2-chloroethyl) benzene may be potentially carcinogenic, and long-term exposure to the environment containing this substance may increase the risk of human cancer. Therefore, the use and discharge of (2-chloroethyl) benzene should be strictly controlled to protect the environment and human well-being.
At the environmental end, (2-chloroethyl) benzene has a certain volatility and can escape into the atmosphere. In the atmosphere, it may participate in photochemical reactions, which may disturb the chemical composition of the atmosphere, thereby affecting air quality. And if it settles into soil and water bodies through processes such as rainwater initialization, in soil, it may affect the community structure and function of soil microorganisms and hinder the normal recycling of substances in soil; in water bodies, it will endanger aquatic organisms. Due to its toxicity, it may cause the growth and reproduction of aquatic organisms to be trapped, and even cause the death of some sensitive species, thereby destroying the balance of aquatic ecosystems.
As for human health, (2-chloroethyl) benzene can invade the human body through respiratory tract, skin contact and other pathways. After entering the body, it may cause damage to the nervous system, causing headaches, dizziness, fatigue, drowsiness and other discomforts. Long-term exposure may involve important organs such as the liver and kidneys, affecting their normal metabolism and detoxification functions. In addition, studies have shown that (2-chloroethyl) benzene may be potentially carcinogenic, and long-term exposure to the environment containing this substance may increase the risk of human cancer. Therefore, the use and discharge of (2-chloroethyl) benzene should be strictly controlled to protect the environment and human well-being.
What are the main uses of (2-chloroethyl) benzene?
(2-Chloroethyl) benzene has a wide range of main uses. In the field of organic synthesis, it can be called a key raw material. With its unique structure, it can undergo many chemical reactions to derive a wide range of organic compounds.
In the field of drug development, (2-chloroethyl) benzene also plays an important role. In the synthesis of many drugs, it is used as a starting material. Through exquisite reaction design, molecular structures with specific pharmacological activities are shaped, thus contributing to human health.
Furthermore, in the field of materials science, it also shows extraordinary value. It can be used as a basic material for the preparation of materials with special properties. Through appropriate reaction and processing, the material is endowed with characteristics such as excellent stability and unique optical properties to meet the special needs of materials in different fields.
In the dye industry, (2-chloroethyl) benzene is also useful. With the help of its participation in the reaction, it can provide novel structural units for the synthesis of dyes, enabling dyes to have more brilliant colors, better dyeing properties, and higher light resistance and washing fastness, thereby enhancing the quality and market competitiveness of dye products.
To sum up, (2-chloroethyl) benzene plays an indispensable role in many fields such as organic synthesis, drug development, materials science, and dye industry, and is an extremely important organic compound.
In the field of drug development, (2-chloroethyl) benzene also plays an important role. In the synthesis of many drugs, it is used as a starting material. Through exquisite reaction design, molecular structures with specific pharmacological activities are shaped, thus contributing to human health.
Furthermore, in the field of materials science, it also shows extraordinary value. It can be used as a basic material for the preparation of materials with special properties. Through appropriate reaction and processing, the material is endowed with characteristics such as excellent stability and unique optical properties to meet the special needs of materials in different fields.
In the dye industry, (2-chloroethyl) benzene is also useful. With the help of its participation in the reaction, it can provide novel structural units for the synthesis of dyes, enabling dyes to have more brilliant colors, better dyeing properties, and higher light resistance and washing fastness, thereby enhancing the quality and market competitiveness of dye products.
To sum up, (2-chloroethyl) benzene plays an indispensable role in many fields such as organic synthesis, drug development, materials science, and dye industry, and is an extremely important organic compound.
What are the physical properties of (2-chloroethyl) benzene
(2-Chloroethyl) benzene is also an organic compound. Its physical properties are many, as follows:
Looking at its properties, under room temperature and pressure, (2-chloroethyl) benzene is a colorless and transparent liquid, with a clear and fluid appearance. It can be seen as an ordinary oily liquid, without a special crystal structure.
Smell the smell, this compound emits an aromatic smell, but its smell is slightly different from common aromatic hydrocarbons. Due to the chlorine atoms, the smell may be slightly irritating, but it is not extremely strong and pungent.
When it comes to the boiling point, the boiling point of (2-chloroethyl) benzene is quite high, about 205 ° C - 208 ° C. Due to the intermolecular force, the structure of benzene ring and chloroethyl group in the molecule enhances the attractive force between molecules. To transform it from liquid to gaseous state, a higher temperature is required to overcome this attractive force.
In terms of melting point, it is about -43 ° C. At this low temperature, (2-chloroethyl) benzene condenses from liquid to solid state, showing the characteristics of solid matter.
Above the density, (2-chloroethyl) benzene is larger than water, about 1.072g/cm ³. Therefore, if it is mixed with water, it will sink to the bottom of the water, and the two will be stratified due to density differences.
In terms of solubility, (2-chloroethyl) benzene is insoluble in water, because water is a polar molecule, and (2-chloroethyl) benzene is a non-polar or weakly polar molecule. According to the principle of "similar miscibility", the two are difficult to dissolve each other. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc., and can be uniformly dispersed in such organic solvents to form a uniform and stable solution.
Volatility, (2-chloroethyl) benzene has a certain degree of volatility. Although it is not as volatile as low-boiling organic solvents, some molecules will escape into the air in an open environment after a certain period of time.
Looking at its properties, under room temperature and pressure, (2-chloroethyl) benzene is a colorless and transparent liquid, with a clear and fluid appearance. It can be seen as an ordinary oily liquid, without a special crystal structure.
Smell the smell, this compound emits an aromatic smell, but its smell is slightly different from common aromatic hydrocarbons. Due to the chlorine atoms, the smell may be slightly irritating, but it is not extremely strong and pungent.
When it comes to the boiling point, the boiling point of (2-chloroethyl) benzene is quite high, about 205 ° C - 208 ° C. Due to the intermolecular force, the structure of benzene ring and chloroethyl group in the molecule enhances the attractive force between molecules. To transform it from liquid to gaseous state, a higher temperature is required to overcome this attractive force.
In terms of melting point, it is about -43 ° C. At this low temperature, (2-chloroethyl) benzene condenses from liquid to solid state, showing the characteristics of solid matter.
Above the density, (2-chloroethyl) benzene is larger than water, about 1.072g/cm ³. Therefore, if it is mixed with water, it will sink to the bottom of the water, and the two will be stratified due to density differences.
In terms of solubility, (2-chloroethyl) benzene is insoluble in water, because water is a polar molecule, and (2-chloroethyl) benzene is a non-polar or weakly polar molecule. According to the principle of "similar miscibility", the two are difficult to dissolve each other. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc., and can be uniformly dispersed in such organic solvents to form a uniform and stable solution.
Volatility, (2-chloroethyl) benzene has a certain degree of volatility. Although it is not as volatile as low-boiling organic solvents, some molecules will escape into the air in an open environment after a certain period of time.
What are the chemical properties of (2-chloroethyl) benzene
(2-Chloroethyl) benzene, its chemical properties can be studied. This compound contains benzene ring and chloroethyl group, so it has the characteristics of both.
As far as the benzene ring is concerned, it is aromatic and can undergo electrophilic substitution reaction. In case of ferric bromide catalysis, it can interact with bromine elemental phase, and the bromine atom replaces the hydrogen atom on the benzene ring to obtain brominated (2-chloroethyl) benzene. It can also be co-heated with mixed acids (mixed sulfuric acid and nitric acid), and nitro is introduced into the benzene ring to obtain nitro (2-chloroethyl) benzene.
And the chloroethyl group in its side chain is active. When exposed to an aqueous solution of sodium hydroxide, a hydrolysis reaction can occur, and the chlorine atom is replaced by a hydroxyl group to obtain (2-hydroxyethyl) benzene. If it is co-heated with sodium hydroxide in an alcohol solution, an elimination reaction occurs, resulting in vinyl benzene and hydrogen chloride.
(2-chloroethyl) benzene can also participate in free radical reactions. When there are initiators such as peroxides, the hydrogen on the methylene side chain can be replaced by free radicals such as halogen atoms.
Because of its certain chemical activity, it is quite useful in the field of organic synthesis. It can be used as a raw material for the synthesis of various organic compounds. With its reaction characteristics, a variety of organic molecular structures can be constructed.
As far as the benzene ring is concerned, it is aromatic and can undergo electrophilic substitution reaction. In case of ferric bromide catalysis, it can interact with bromine elemental phase, and the bromine atom replaces the hydrogen atom on the benzene ring to obtain brominated (2-chloroethyl) benzene. It can also be co-heated with mixed acids (mixed sulfuric acid and nitric acid), and nitro is introduced into the benzene ring to obtain nitro (2-chloroethyl) benzene.
And the chloroethyl group in its side chain is active. When exposed to an aqueous solution of sodium hydroxide, a hydrolysis reaction can occur, and the chlorine atom is replaced by a hydroxyl group to obtain (2-hydroxyethyl) benzene. If it is co-heated with sodium hydroxide in an alcohol solution, an elimination reaction occurs, resulting in vinyl benzene and hydrogen chloride.
(2-chloroethyl) benzene can also participate in free radical reactions. When there are initiators such as peroxides, the hydrogen on the methylene side chain can be replaced by free radicals such as halogen atoms.
Because of its certain chemical activity, it is quite useful in the field of organic synthesis. It can be used as a raw material for the synthesis of various organic compounds. With its reaction characteristics, a variety of organic molecular structures can be constructed.
What are the synthesis methods of (2-chloroethyl) benzene
For (2-chloroethyl) benzene, there are various methods for synthesis. One is to use benzene and chloroethanol as raw materials, and sulfuric acid or anhydrous zinc chloride as catalysts to carry out nucleophilic substitution. In this reaction, the aromatic ring of benzene has an electron cloud density, and the hydroxyl group of chloroethyl alcohol is converted into an easy-to-leave group under the action of the catalyst, and then the electron cloud of benzene attacks the carbon center to form (2-chloroethyl) benzene.
Furthermore, ethylene and benzene can be alkylated by Fu-g under the action of an appropriate catalyst such as aluminum trichloride to obtain ethylbenzene. Then, the side chain of ethylbenzene is halogenated with chlorine gas as a halogenating agent in the presence of light or an initiator. Due to the reactivity of side chain α-hydrogen, it is easy to form a free radical intermediate under the action of light or an initiator, and the chlorine radical is combined with the intermediate to obtain (2-chloroethyl) benzene.
There are also those who use styrene as a raw material to first add styrene to hydrogen chloride. This addition follows the Markov rule. The hydrogen atom is added to the double-bonded carbon atom with more hydrogen, and the chlorine atom is added to the double-bonded carbon atom with less hydrogen, thereby generating (2-chloroethyl) benzene. The reaction conditions are mild and the operation is relatively simple.
This number method has its own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively weigh the availability of raw materials, cost, reaction conditions and product purity and other factors to choose the appropriate method.
Furthermore, ethylene and benzene can be alkylated by Fu-g under the action of an appropriate catalyst such as aluminum trichloride to obtain ethylbenzene. Then, the side chain of ethylbenzene is halogenated with chlorine gas as a halogenating agent in the presence of light or an initiator. Due to the reactivity of side chain α-hydrogen, it is easy to form a free radical intermediate under the action of light or an initiator, and the chlorine radical is combined with the intermediate to obtain (2-chloroethyl) benzene.
There are also those who use styrene as a raw material to first add styrene to hydrogen chloride. This addition follows the Markov rule. The hydrogen atom is added to the double-bonded carbon atom with more hydrogen, and the chlorine atom is added to the double-bonded carbon atom with less hydrogen, thereby generating (2-chloroethyl) benzene. The reaction conditions are mild and the operation is relatively simple.
This number method has its own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively weigh the availability of raw materials, cost, reaction conditions and product purity and other factors to choose the appropriate method.
What are the precautions for (2-chloroethyl) benzene during use?
(2-Chloroethyl) benzene is also a chemical substance. During the course of use, it is important to pay attention to it.
First, it is toxic to a certain extent, and it can cause harm if it is exposed or inhaled. If the skin is connected, wash it with a large amount of water as soon as possible, and wash it with soap. If it enters the eye, immediately wash it with a large amount of water and ask for it as soon as possible. If inhaled, it is necessary to give artificial respiration as soon as possible.
Second, (2-chloroethyl) benzene is flammable, and it is easy to ignite and explode when exposed to open flames and high temperatures. If you want to store it, avoid open flames and sources, and keep it in the right place. And it should not exceed 30 ° C. Oxidation and other substances should be used to prevent fire and explosions.
Furthermore, the use of anti-toxins must be properly prevented. The operator wears anti-toxin work clothes, wears chemical safety and anti-eye protection, anti-toxin work shoes, and rubber oil-resistant gloves for his own safety.
In addition, the use of (2-chloroethyl) benzene is good. It can be partially discharged or fully passed to reduce its temperature in the air and avoid the risk of poisoning.
The last one, the (2-chloroethyl) benzene, should not be used. According to the phase method, leave it in place to properly manage and avoid staining the environment.
In addition, use (2-chloroethyl) benzene, and pay attention to all things, so that the security is complete and the harm is avoided.
First, it is toxic to a certain extent, and it can cause harm if it is exposed or inhaled. If the skin is connected, wash it with a large amount of water as soon as possible, and wash it with soap. If it enters the eye, immediately wash it with a large amount of water and ask for it as soon as possible. If inhaled, it is necessary to give artificial respiration as soon as possible.
Second, (2-chloroethyl) benzene is flammable, and it is easy to ignite and explode when exposed to open flames and high temperatures. If you want to store it, avoid open flames and sources, and keep it in the right place. And it should not exceed 30 ° C. Oxidation and other substances should be used to prevent fire and explosions.
Furthermore, the use of anti-toxins must be properly prevented. The operator wears anti-toxin work clothes, wears chemical safety and anti-eye protection, anti-toxin work shoes, and rubber oil-resistant gloves for his own safety.
In addition, the use of (2-chloroethyl) benzene is good. It can be partially discharged or fully passed to reduce its temperature in the air and avoid the risk of poisoning.
The last one, the (2-chloroethyl) benzene, should not be used. According to the phase method, leave it in place to properly manage and avoid staining the environment.
In addition, use (2-chloroethyl) benzene, and pay attention to all things, so that the security is complete and the harm is avoided.
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