Linshang Chemical
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(2-Chloroethoxy)Methylbenzene
Linshang Chemical
|
HS Code |
172788 |
| Chemical Formula | C9H11ClO |
| Molecular Weight | 170.636 g/mol |
| Appearance | Colorless to light - yellow liquid |
| Boiling Point | 222 - 224 °C |
| Density | 1.106 g/cm³ |
| Flash Point | 92 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Vapor Pressure | Low vapor pressure at room temperature |
| Odor | Characteristic aromatic odor |
| Stability | Stable under normal conditions |
As an accredited (2-Chloroethoxy)Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottles for (2 - chloroethoxy)methylbenzene, well - sealed for chemical storage. |
| Storage | (2 - chloroethoxy)methylbenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent potential reactions. Regularly check storage conditions for any signs of leakage or degradation. |
| Shipping | (2 - chloroethoxy)methylbenzene should be shipped in accordance with hazardous chemical regulations. It must be properly packaged in suitable containers to prevent leakage, and transported by carriers licensed for such chemicals with safety precautions in place. |
Competitive (2-Chloroethoxy)Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
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What is the main use of (2-chloroethoxy) methylbenzene?
(2-Chloroethoxy) methyl benzene has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, the chlorine atom is connected to the phenyl ring and ethoxy group, and this special structure enables it to participate in various chemical reactions.
First, it can be used to prepare various ether compounds. Through nucleophilic substitution reaction, the chlorine atom can be replaced by other nucleophiles, thereby forming a new carbon-oxygen bond to obtain ethers with different structures. This is of great significance in drug synthesis. Many drug molecules contain ether bonds. (2-chloroethoxy) methyl benzene can provide basic raw materials for the synthesis of such drugs.
Second, it is also used in materials science. It can participate in the synthesis of polymer materials, and introduce specific groups into the polymer chain through its reactivity to improve the properties of the material, such as solubility and thermal stability.
Third, in the field of fragrance industry, it can be used as an intermediary for fragrance synthesis. Due to the presence of benzene ring, the substance is endowed with certain aromatic properties. After further reaction modification, it may generate fragrance components with unique aroma.
In short, (2-chloroethoxy) methyl benzene plays an important role in many fields such as organic synthesis, materials science, and fragrance industry, and is indispensable to the development of modern chemical industry.
First, it can be used to prepare various ether compounds. Through nucleophilic substitution reaction, the chlorine atom can be replaced by other nucleophiles, thereby forming a new carbon-oxygen bond to obtain ethers with different structures. This is of great significance in drug synthesis. Many drug molecules contain ether bonds. (2-chloroethoxy) methyl benzene can provide basic raw materials for the synthesis of such drugs.
Second, it is also used in materials science. It can participate in the synthesis of polymer materials, and introduce specific groups into the polymer chain through its reactivity to improve the properties of the material, such as solubility and thermal stability.
Third, in the field of fragrance industry, it can be used as an intermediary for fragrance synthesis. Due to the presence of benzene ring, the substance is endowed with certain aromatic properties. After further reaction modification, it may generate fragrance components with unique aroma.
In short, (2-chloroethoxy) methyl benzene plays an important role in many fields such as organic synthesis, materials science, and fragrance industry, and is indispensable to the development of modern chemical industry.
What are the physical properties of (2-chloroethoxy) methylbenzene
(2-Chloroethoxy) methyl benzene, its physical state is mostly liquid at room temperature, and it looks clear and transparent, like glass, with a fragrant smell, leisurely like ancient incense, fragrant. Its melting point is quite low, about -50 ° C below, so it is difficult to condense it into a solid state in cold weather. The boiling point is between 210-220 ° C. When heated to this point, it turns into a curling hot gas.
This substance has a slightly lighter density than water. If placed in water, it is as distinct as oil floating on water. In terms of solubility, it is extremely insoluble in water, just like the incompatibility of oil and water. However, organic solvents, such as ethanol, ether, acetone, etc., are miscible, just like water emulsion blending, without hindrance.
Its volatility is weak, unlike that of spirits. The stability is acceptable, and under normal circumstances, it is not easy to decompose on its own or react violently with other things. In case of open flames, hot topics, or dry wood in case of fire, it is very easy to burn, and the fire is rapid. When burning, bright flames can be seen, accompanied by thick smoke rising.
In addition, it has certain toxicity, although it is not highly toxic, if it accidentally touches the skin, such as the ancient poisonous grass touching the skin, it can cause redness, swelling and itching of the skin; if it inhales its vapor, such as smelling the gas of miasma, it will also irritate the respiratory tract and cause discomfort. Therefore, when using it, it should be treated with caution like walking on thin ice in the abyss.
This substance has a slightly lighter density than water. If placed in water, it is as distinct as oil floating on water. In terms of solubility, it is extremely insoluble in water, just like the incompatibility of oil and water. However, organic solvents, such as ethanol, ether, acetone, etc., are miscible, just like water emulsion blending, without hindrance.
Its volatility is weak, unlike that of spirits. The stability is acceptable, and under normal circumstances, it is not easy to decompose on its own or react violently with other things. In case of open flames, hot topics, or dry wood in case of fire, it is very easy to burn, and the fire is rapid. When burning, bright flames can be seen, accompanied by thick smoke rising.
In addition, it has certain toxicity, although it is not highly toxic, if it accidentally touches the skin, such as the ancient poisonous grass touching the skin, it can cause redness, swelling and itching of the skin; if it inhales its vapor, such as smelling the gas of miasma, it will also irritate the respiratory tract and cause discomfort. Therefore, when using it, it should be treated with caution like walking on thin ice in the abyss.
Is (2-chloroethoxy) methylbenzene chemically stable?
The chemical stability of (2-chloroethoxy) methyl benzene depends on many factors. Looking at the structure of this compound, the benzene ring has a certain stability, but the (2-chloroethoxy) part of the side chain may change the overall properties.
Chlorine atoms are often active in organic compounds. In (2-chloroethoxy) methyl benzene, chlorine atoms can cause nucleophilic substitution reactions. Because of its strong electronegativity, it can make the connected carbon atoms partially positively charged, making them vulnerable to nucleophilic reagents. Suppose there are nucleophiles such as hydroxide ions in a suitable environment, or initiate the reaction of chlorine atom being replaced by hydroxyl group, thereby changing the structure and properties of the compound.
Furthermore, the existence of ethoxy group also affects its properties. Ethoxy group is the power supply group, which can increase the electron cloud density of the benzene ring and affect the reactivity of the benzene ring to a certain extent. In the electrophilic substitution reaction, it may make the reaction more likely to occur, and the localization effect also needs to be considered.
And due to (2-chloroethoxy) methyl benzene organic compounds, they are affected by heat, light and other conditions, or decompose and isomerize. When heated, the chemical bonds in the molecule may be broken and rearranged due to the increase of energy; under light, photochemical reactions may be induced to generate new products.
In summary, the chemical properties of (2-chloroethoxy) methyl benzene are difficult to say absolutely stable, and under different environmental conditions, they may exhibit various reactivity and changes.
Chlorine atoms are often active in organic compounds. In (2-chloroethoxy) methyl benzene, chlorine atoms can cause nucleophilic substitution reactions. Because of its strong electronegativity, it can make the connected carbon atoms partially positively charged, making them vulnerable to nucleophilic reagents. Suppose there are nucleophiles such as hydroxide ions in a suitable environment, or initiate the reaction of chlorine atom being replaced by hydroxyl group, thereby changing the structure and properties of the compound.
Furthermore, the existence of ethoxy group also affects its properties. Ethoxy group is the power supply group, which can increase the electron cloud density of the benzene ring and affect the reactivity of the benzene ring to a certain extent. In the electrophilic substitution reaction, it may make the reaction more likely to occur, and the localization effect also needs to be considered.
And due to (2-chloroethoxy) methyl benzene organic compounds, they are affected by heat, light and other conditions, or decompose and isomerize. When heated, the chemical bonds in the molecule may be broken and rearranged due to the increase of energy; under light, photochemical reactions may be induced to generate new products.
In summary, the chemical properties of (2-chloroethoxy) methyl benzene are difficult to say absolutely stable, and under different environmental conditions, they may exhibit various reactivity and changes.
What are the synthesis methods of (2-chloroethoxy) methylbenzene
The synthesis method of (2-chloroethoxy) methyl benzene is a very important topic in the field of organic synthesis. There are several common methods for the synthesis of this compound.
First, benzyl alcohol and 2-chloroethanol are used as raw materials, under the action of appropriate catalysts, by etherification. Usually, an acidic catalyst can be selected, such as p-toluenesulfonic acid. At a suitable reaction temperature and reaction time, the two undergo a nucleophilic substitution reaction. The hydroxyl oxygen atom of benzyl alcohol attacks the carbon atom connected to the chlorine atom of 2-chloroethanol, and the chloride ion leaves to form (2-chloroethoxy) benzyl. This process requires attention to the precise control of the reaction conditions. If the temperature is too high or too low, it may affect the yield and selectivity of the reaction.
Second, benzyl chloride is reacted with sodium 2-chloroethyl alcohol as the raw material. First, 2-chloroethyl alcohol interacts with bases such as sodium metal or sodium hydroxide to form sodium 2-chloroethyl alcohol. Subsequently, benzyl chloride undergoes a nucleophilic substitution reaction with sodium 2-chloroethyl alcohol, and the oxygen atom of sodium ethanol attacks the carbon atom connected to the chlorine atom of benzyl chloride, and the chloride ion leaves to obtain the target product. In this method, the preparation of sodium 2-chloroethanol requires careful operation, because it is more sensitive to water, and it is easy to hydrolyze in contact with water, which affects the subsequent reaction.
In addition, it can also be synthesized by phase transfer catalysis. Benzyl chloride and 2-chloroethanol are used as raw materials, and a phase transfer catalyst, such as tetrabutylammonium bromide, is added. The phase transfer catalyst can promote the transfer of ions in the reaction system, making the reaction easier to occur at the two-phase interface, thereby improving the reaction rate and yield. This method is relatively simple to operate and the reaction conditions are relatively mild, but the choice and dosage of phase transfer catalyst also have a significant impact on the reaction effect.
The above synthesis methods each have their own advantages and disadvantages. In practical applications, it is necessary to choose the appropriate synthesis path according to the specific circumstances, such as the availability of raw materials, the difficulty of controlling the reaction conditions, and the purity requirements of the product.
First, benzyl alcohol and 2-chloroethanol are used as raw materials, under the action of appropriate catalysts, by etherification. Usually, an acidic catalyst can be selected, such as p-toluenesulfonic acid. At a suitable reaction temperature and reaction time, the two undergo a nucleophilic substitution reaction. The hydroxyl oxygen atom of benzyl alcohol attacks the carbon atom connected to the chlorine atom of 2-chloroethanol, and the chloride ion leaves to form (2-chloroethoxy) benzyl. This process requires attention to the precise control of the reaction conditions. If the temperature is too high or too low, it may affect the yield and selectivity of the reaction.
Second, benzyl chloride is reacted with sodium 2-chloroethyl alcohol as the raw material. First, 2-chloroethyl alcohol interacts with bases such as sodium metal or sodium hydroxide to form sodium 2-chloroethyl alcohol. Subsequently, benzyl chloride undergoes a nucleophilic substitution reaction with sodium 2-chloroethyl alcohol, and the oxygen atom of sodium ethanol attacks the carbon atom connected to the chlorine atom of benzyl chloride, and the chloride ion leaves to obtain the target product. In this method, the preparation of sodium 2-chloroethanol requires careful operation, because it is more sensitive to water, and it is easy to hydrolyze in contact with water, which affects the subsequent reaction.
In addition, it can also be synthesized by phase transfer catalysis. Benzyl chloride and 2-chloroethanol are used as raw materials, and a phase transfer catalyst, such as tetrabutylammonium bromide, is added. The phase transfer catalyst can promote the transfer of ions in the reaction system, making the reaction easier to occur at the two-phase interface, thereby improving the reaction rate and yield. This method is relatively simple to operate and the reaction conditions are relatively mild, but the choice and dosage of phase transfer catalyst also have a significant impact on the reaction effect.
The above synthesis methods each have their own advantages and disadvantages. In practical applications, it is necessary to choose the appropriate synthesis path according to the specific circumstances, such as the availability of raw materials, the difficulty of controlling the reaction conditions, and the purity requirements of the product.
What are the precautions for (2-chloroethoxy) methylbenzene in storage and transportation?
When storing and transporting (2-chloroethoxy) methyl benzene, it is necessary to pay attention to many matters.
The first thing to pay attention to is its chemical properties. This is an organic compound, flammable, and the presence of chlorine atoms makes its chemical activity different. When storing, choose a cool, dry and well-ventilated place, away from fire and heat sources, to avoid the risk of fire and explosion. Because of its flammability, it can burn violently in case of open flames and hot topics, so fireworks are strictly prohibited in the storage place, and fire extinguishing facilities such as dry powder fire extinguishers, carbon dioxide fire extinguishers, etc. should be prepared to prevent accidents.
Furthermore, (2-chloroethoxy) methyl benzene may have certain toxicity and irritation. During transportation, the packaging must be tight to prevent leakage. If leakage occurs, it will not only pollute the environment, but also cause harm to the human body. Operators need to wear appropriate protective equipment, such as gas masks, protective gloves, protective clothing, etc., to avoid contact with the skin and respiratory tract. In case of accidental contact, rinse with plenty of water immediately, and seek medical treatment according to the severity of the injury.
In addition, during storage and transportation, relevant regulations and standards should be strictly followed. Documentation and records must be complete, covering the quantity, source, whereabouts and other information of the goods for traceability and supervision. Transportation vehicles should also meet safety requirements and be equipped with anti-static and anti-leakage devices to ensure stable transportation. Only in this way can we ensure the safety of (2-chloroethoxy) methyl benzene storage and transportation, avoid accidents, and protect the safety of personnel and the environment.
The first thing to pay attention to is its chemical properties. This is an organic compound, flammable, and the presence of chlorine atoms makes its chemical activity different. When storing, choose a cool, dry and well-ventilated place, away from fire and heat sources, to avoid the risk of fire and explosion. Because of its flammability, it can burn violently in case of open flames and hot topics, so fireworks are strictly prohibited in the storage place, and fire extinguishing facilities such as dry powder fire extinguishers, carbon dioxide fire extinguishers, etc. should be prepared to prevent accidents.
Furthermore, (2-chloroethoxy) methyl benzene may have certain toxicity and irritation. During transportation, the packaging must be tight to prevent leakage. If leakage occurs, it will not only pollute the environment, but also cause harm to the human body. Operators need to wear appropriate protective equipment, such as gas masks, protective gloves, protective clothing, etc., to avoid contact with the skin and respiratory tract. In case of accidental contact, rinse with plenty of water immediately, and seek medical treatment according to the severity of the injury.
In addition, during storage and transportation, relevant regulations and standards should be strictly followed. Documentation and records must be complete, covering the quantity, source, whereabouts and other information of the goods for traceability and supervision. Transportation vehicles should also meet safety requirements and be equipped with anti-static and anti-leakage devices to ensure stable transportation. Only in this way can we ensure the safety of (2-chloroethoxy) methyl benzene storage and transportation, avoid accidents, and protect the safety of personnel and the environment.
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